Page last updated: 2024-09-05

troleandomycin and nicardipine

troleandomycin has been researched along with nicardipine in 2 studies

Compound Research Comparison

Studies (troleandomycin)	Trials (troleandomycin)	Recent Studies (post-2010) (troleandomycin)	Studies (nicardipine)	Trials (nicardipine)	Recent Studies (post-2010) (nicardipine)
569	26	23	2,646	444	312

Protein Interaction Comparison

Protein	Taxonomy	nicardipine (IC50)
Bile salt export pump	Homo sapiens (human)	8.314
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	8
ATP-dependent translocase ABCB1	Homo sapiens (human)	4.2992
Cytochrome P450 3A4	Homo sapiens (human)	0.42
Cytochrome P450 2C9	Homo sapiens (human)	1.69
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	2.5
Cytochrome P450 2J2	Homo sapiens (human)	1.69
Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)	4.925
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	4.8

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1

Other Studies

2 other study(ies) available for troleandomycin and nicardipine

Article	Year
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors. Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2 Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors	2001
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013

Article

Year

Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.

Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2

Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors

2001

Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.

Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013