Compounds > troleandomycin
Page last updated: 2024-09-05

troleandomycin and nadp

troleandomycin has been researched along with nadp in 11 studies

Compound Research Comparison

Studies
(troleandomycin)		Trials
(troleandomycin)		Recent Studies (post-2010)
(troleandomycin)		Studies
(nadp)		Trials
(nadp)		Recent Studies (post-2010) (nadp)
569262321,608253,484

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's4 (36.36)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belghiti, J; Larrey, D; Lettéron, P; Loeper, J; Maurel, P; Pessayre, D; Tinel, M1
Ciaccio, PJ; Halpert, JR1
Attisano, C; Guengerich, FP; Lapenson, DP; Waxman, DJ1
Correia, MA; Decker, C; Sugiyama, K; Underwood, M1
Lange, R; Larroque, C1
Hanssen, BR; Lindstrom, TD; Wrighton, SA1
Mason, SR; Read, MA; Reilly, PE1
Arai, N; Fujimaki, Y; Inaba, T1
Floreani, M; Geroni, C; Napoli, E; Quintieri, L; Rosato, A; Sola, F; Zanovello, P1
Baillie, TA; Braun, MP; Chen, Q; Didolkar, V; Doss, GA; Evans, DC; Liu, W; Stearns, RA; Strauss, JR; Tang, W; Tang, YS; Tung, EC; Wang, RW1
Amunom, I; Cai, J; Conklin, DJ; Dieter, LJ; Guengerich, FP; Martin, MV; Prough, RA; Srivastava, S; Tamasi, V1

Other Studies

11 other study(ies) available for troleandomycin and nadp

ArticleYear
Metabolic activation of the new tricyclic antidepressant tianeptine by human liver cytochrome P450.
    Biochemical pharmacology, 1990, Aug-01, Volume: 40, Issue:3

    Topics: Antidepressive Agents, Tricyclic; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Glutathione; Humans; Isoenzymes; Microsomes, Liver; NADP; Oxygen; Piperonyl Butoxide; Pyridines; Quinidine; Troleandomycin

1990
Characterization of a phenobarbital-inducible dog liver cytochrome P450 structurally related to rat and human enzymes of the P450IIIA (steroid-inducible) gene subfamily.
    Archives of biochemistry and biophysics, 1989, Volume: 271, Issue:2

    Topics: Amino Acid Sequence; Animals; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Enzyme Induction; Immunoblotting; Immunoglobulin G; Kinetics; Male; Microsomes, Liver; Molecular Sequence Data; Molecular Weight; NADP; Phenobarbital; Rats; Spectrophotometry; Steroid Hydroxylases; Troleandomycin

1989
Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme.
    Archives of biochemistry and biophysics, 1988, Volume: 263, Issue:2

    Topics: Androstenedione; Animals; Cross Reactions; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Humans; Male; Microsomes, Liver; NADP; Progesterone; Rats; Steroid Hydroxylases; Substrate Specificity; Testosterone; Troleandomycin

1988
Inactivation of rat hepatic cytochrome P-450 by spironolactone.
    Biochemical and biophysical research communications, 1986, May-14, Volume: 136, Issue:3

    Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Dexamethasone; Drug Synergism; Heme; Male; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains; Spironolactone; Time Factors; Troleandomycin

1986
Interaction of carbon tetrachloride and progesterone metabolism in liver microsomes from triacetyloleandomycin-treated rats.
    Archives of toxicology, 1987, Volume: 60, Issue:1-3

    Topics: Animals; Carbon Tetrachloride; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Male; Microsomes, Liver; NADP; Progesterone; Rats; Rats, Inbred Strains; Troleandomycin

1987
Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Humans; In Vitro Techniques; Macrolides; Male; Microsomes, Liver; NADP; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Troleandomycin

1993
Human, rat and crocodile liver microsomal monooxygenase activities measured using diazepam and nifedipine: effects of CYP3A inhibitors and relationship to immunochemically detected CYP3A apoprotein.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1999, Volume: 122, Issue:2

    Topics: Alligators and Crocodiles; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Enzyme Inhibitors; Female; Humans; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nifedipine; Oxidoreductases, N-Demethylating; Rats; Rats, Wistar; Sex Characteristics; Species Specificity; Substrate Specificity; Troleandomycin

1999
Identification of cytochromes P450 involved in human liver microsomal metabolism of ecabapide, a prokinetic agent.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:12

    Topics: Anti-Ulcer Agents; Benzamides; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Inactivation, Metabolic; Isoenzymes; Ketoconazole; Miconazole; Microsomes, Liver; NADP; Substrate Specificity; Troleandomycin

1999
In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
    Cancer research, 2000, Jun-15, Volume: 60, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Bone Marrow; Coculture Techniques; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Doxorubicin; Erythromycin; Female; Leukemia, Experimental; Liver; Liver Neoplasms, Experimental; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; NADP; Neoplasm Transplantation; Neoplasms, Experimental; Oxidoreductases, N-Demethylating; Pregnenolone Carbonitrile; Protein Synthesis Inhibitors; Time Factors; Troleandomycin; Tumor Cells, Cultured

2000
Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:1

    Topics: Animals; Chromatography, Liquid; Female; Glutathione; Hepatocytes; Humans; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Spectrometry, Mass, Electrospray Ionization; Tolmetin; Tritium; Troleandomycin

2006
Cytochromes P450 catalyze the reduction of α,β-unsaturated aldehydes.
    Chemical research in toxicology, 2011, Aug-15, Volume: 24, Issue:8

    Topics: Aldehydes; Animals; Anthracenes; Biocatalysis; Cells, Cultured; Cyanamide; Cytochrome P-450 CYP3A; Hepatocytes; Humans; Hydroxy Acids; Male; Mice; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Troleandomycin

2011