troleandomycin has been researched along with meperidine in 3 studies
| Studies (troleandomycin) | Trials (troleandomycin) | Recent Studies (post-2010) (troleandomycin) | Studies (meperidine) | Trials (meperidine) | Recent Studies (post-2010) (meperidine) |
|---|---|---|---|---|---|
| 569 | 26 | 23 | 5,748 | 1,228 | 343 |
| Protein | Taxonomy | troleandomycin (IC50) | meperidine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.5 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.5 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.4075 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.5 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 1.435 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.5 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.5 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.3236 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Al-Shurbaji, A; Annas, A; Artursson, P; Lazorova, L; Svensson, JO; Yasar, U | 1 |
3 other study(ies) available for troleandomycin and meperidine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Caco-2 Cells; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Isonipecotic Acids; Ketoconazole; Kinetics; Meperidine; Microsomes, Liver; Mutagenesis, Site-Directed; Phenols; Substrate Specificity; Sulfaphenazole; Troleandomycin; Verapamil | 2005 |