troleandomycin has been researched along with loratadine in 1 studies
| Studies (troleandomycin) | Trials (troleandomycin) | Recent Studies (post-2010) (troleandomycin) | Studies (loratadine) | Trials (loratadine) | Recent Studies (post-2010) (loratadine) |
|---|---|---|---|---|---|
| 569 | 26 | 23 | 1,317 | 462 | 339 |
| Protein | Taxonomy | troleandomycin (IC50) | loratadine (IC50) |
|---|---|---|---|
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.016 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.23 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.245 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.1717 | |
| Bile acid receptor | Homo sapiens (human) | 3.07 | |
| Sodium-dependent neutral amino acid transporter B(0)AT2 | Homo sapiens (human) | 4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cayen, MN; Chen, KJ; Clement, RP; Huie, K; Snow, M; Yumibe, N | 1 |
1 other study(ies) available for troleandomycin and loratadine
| Article | Year |
|---|---|
Identification of human liver cytochrome P450 enzymes that metabolize the nonsedating antihistamine loratadine. Formation of descarboethoxyloratadine by CYP3A4 and CYP2D6.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Binding Sites; Biotransformation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Histamine H1 Antagonists; Humans; In Vitro Techniques; Ketoconazole; Loratadine; Microsomes, Liver; Mixed Function Oxygenases; Models, Molecular; Oxidation-Reduction; Piperidines; Pyridines; Quinidine; Recombinant Proteins; Substrate Specificity; Troleandomycin | 1996 |