Page last updated: 2024-09-05

troleandomycin and leucine

troleandomycin has been researched along with leucine in 2 studies

Compound Research Comparison

Studies (troleandomycin)	Trials (troleandomycin)	Recent Studies (post-2010) (troleandomycin)	Studies (leucine)	Trials (leucine)	Recent Studies (post-2010) (leucine)
569	26	23	28,515	744	4,178

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Fowler, SM; Friedberg, T; Riley, RJ; Taylor, JM; Wolf, CR	1

Other Studies

2 other study(ies) available for troleandomycin and leucine

Article	Year
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
CYP3A4 active site volume modification by mutagenesis of leucine 211. Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:4 Topics: Amino Acid Substitution; Anti-Anxiety Agents; Anti-Bacterial Agents; Binding Sites; Coumarins; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diazepam; Enzyme Activation; Enzyme Inhibitors; Erythromycin; Hydroxylation; Kinetics; Leucine; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Oxidation-Reduction; Structure-Activity Relationship; Substrate Specificity; Testosterone; Troleandomycin	2002

Article

Year

Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.

Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012

CYP3A4 active site volume modification by mutagenesis of leucine 211.

Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:4

Topics: Amino Acid Substitution; Anti-Anxiety Agents; Anti-Bacterial Agents; Binding Sites; Coumarins; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diazepam; Enzyme Activation; Enzyme Inhibitors; Erythromycin; Hydroxylation; Kinetics; Leucine; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Oxidation-Reduction; Structure-Activity Relationship; Substrate Specificity; Testosterone; Troleandomycin

2002