troleandomycin has been researched along with ibuprofen in 5 studies
| Studies (troleandomycin) | Trials (troleandomycin) | Recent Studies (post-2010) (troleandomycin) | Studies (ibuprofen) | Trials (ibuprofen) | Recent Studies (post-2010) (ibuprofen) |
|---|---|---|---|---|---|
| 569 | 26 | 23 | 10,245 | 1,781 | 4,267 |
| Protein | Taxonomy | troleandomycin (IC50) | ibuprofen (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 2.9 | |
| Prostaglandin G/H synthase 2 | Bos taurus (cattle) | 1.1 | |
| Albumin | Bos taurus (cattle) | 3 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 4.0919 | |
| Prostaglandin G/H synthase 1 | Mus musculus (house mouse) | 0.22 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 1.6273 | |
| Caspase-1 | Homo sapiens (human) | 7.2667 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 1.1 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 3.0687 | |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | 1.3 | |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | 10 | |
| Caspase-3 | Homo sapiens (human) | 7.2667 | |
| Caspase-4 | Homo sapiens (human) | 7.2667 | |
| 4-aminobutyrate aminotransferase, mitochondrial | Rattus norvegicus (Norway rat) | 1.1 | |
| Caspase-5 | Homo sapiens (human) | 7.2667 | |
| Caspase-9 | Homo sapiens (human) | 7.2667 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 1.1375 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 2.9 | |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | 5 | |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 0.54 | |
| Solute carrier family 22 member 6 | Homo sapiens (human) | 8 | |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | 1.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
5 other study(ies) available for troleandomycin and ibuprofen
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |