troleandomycin has been researched along with ethinyl estradiol in 8 studies
| Studies (troleandomycin) | Trials (troleandomycin) | Recent Studies (post-2010) (troleandomycin) | Studies (ethinyl estradiol) | Trials (ethinyl estradiol) | Recent Studies (post-2010) (ethinyl estradiol) |
|---|---|---|---|---|---|
| 569 | 26 | 23 | 9,070 | 1,566 | 1,732 |
| Protein | Taxonomy | troleandomycin (IC50) | ethinyl estradiol (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 2 | Homo sapiens (human) | 2.2 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Estrogen receptor | Homo sapiens (human) | 0.0035 | |
| Glucocorticoid receptor | Homo sapiens (human) | 1.71 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 1.71 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.959 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 5.678 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 4.8812 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 1.71 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 1.71 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.959 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 1.71 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.054 | |
| Sulfotransferase 1A1 | Homo sapiens (human) | 0.02 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.559 | |
| Aldehyde oxidase | Homo sapiens (human) | 0.57 | |
| Nuclear receptor subfamily 1 group I member 3 | Homo sapiens (human) | 3 | |
| Estrogen receptor beta | Homo sapiens (human) | 0.0129 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Back, DJ; Houlgrave, R; Orme, ML; Tjia, JF; Ward, S | 1 |
| Guengerich, FP | 1 |
| Andrieu, J; Doll, J; Gardon, JD; Jean, F | 1 |
1 review(s) available for troleandomycin and ethinyl estradiol
| Article | Year |
|---|---|
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
7 other study(ies) available for troleandomycin and ethinyl estradiol
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Effect of the progestogens, gestodene, 3-keto desogestrel, levonorgestrel, norethisterone and norgestimate on the oxidation of ethinyloestradiol and other substrates by human liver microsomes.
Topics: Contraceptives, Oral; Cytochrome P-450 Enzyme Inhibitors; Diazepam; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hydroxylation; In Vitro Techniques; Microsomes, Liver; Norethindrone; Norgestrel; Norpregnenes; Progestins; Troleandomycin | 1991 |
Oxidation of 17 alpha-ethynylestradiol by human liver cytochrome P-450.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ethinyl Estradiol; Humans; Immunologic Techniques; In Vitro Techniques; Microsomes, Liver; Nifedipine; Oxidation-Reduction; Substrate Specificity; Troleandomycin | 1988 |
[Cholestatic icterus in the course of ethinyl-estradiol therapy].
Topics: Ethinyl Estradiol; Female; Humans; Jaundice; Middle Aged; Troleandomycin | 1981 |