Page last updated: 2024-09-05

troleandomycin and ergotamine

troleandomycin has been researched along with ergotamine in 6 studies

Compound Research Comparison

Studies
(troleandomycin)
Trials
(troleandomycin)
Recent Studies (post-2010)
(troleandomycin)
Studies
(ergotamine)
Trials
(ergotamine)
Recent Studies (post-2010) (ergotamine)
56926232,352103103

Protein Interaction Comparison

ProteinTaxonomytroleandomycin (IC50)ergotamine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.056
Tyrosine-protein kinase LckHomo sapiens (human)6.499
Tyrosine-protein kinase FynHomo sapiens (human)3.16
Beta-2 adrenergic receptorHomo sapiens (human)2.761
Beta-1 adrenergic receptorHomo sapiens (human)4.142
Cytochrome P450 3A4Homo sapiens (human)1
Alpha-2A adrenergic receptorHomo sapiens (human)0.0021
D(2) dopamine receptorHomo sapiens (human)0.0043
Alpha-2B adrenergic receptorHomo sapiens (human)0.0038
Alpha-2C adrenergic receptorHomo sapiens (human)0.012
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0008
D(1A) dopamine receptorHomo sapiens (human)1.728
Thromboxane-A synthase Homo sapiens (human)3.064
Alpha-1D adrenergic receptorHomo sapiens (human)0.049
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0065
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.056
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0008
D(3) dopamine receptorHomo sapiens (human)0.0043
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0035
5-hydroxytryptamine receptor 6Homo sapiens (human)0.002

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dantzig, AH; Ekins, S; Kim, RB; Lan, LB; Leake, BF; Schuetz, EG; Schuetz, JD; Shepard, RL; Wikel, JH; Winter, MA; Wrighton, SA; Yasuda, K1
Furuya, K; Lan, LB; Sanglard, D; Schuetz, EG; Schuetz, JD; Yasuda, K1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Aimez, P; Bigorie, B; Bour, H; di Maria, G; Guy-Grand, B; Samama, F; Soria, RJ1
Lesca, H; Ossard, D; Reynier, P1
Hayton, AC1

Other Studies

6 other study(ies) available for troleandomycin and ergotamine

ArticleYear
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein.
    Molecular pharmacology, 2002, Volume: 61, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Ergonovine; Fluoxetine; Humans; Models, Molecular; Oxytocics; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Swine; Transfection; Vinblastine

2002
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroergocryptine; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; Mice; Mice, Knockout; Microsomes, Liver; Oxidoreductases, N-Demethylating; Recombinant Proteins; Reserpine; Swine; Tissue Distribution; Transfection; Vinblastine

2002
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Is triacetyl oleandomycin-ergotamine tartrate combination dangerous?].
    La Nouvelle presse medicale, 1975, Nov-08, Volume: 4, Issue:38

    Topics: Adolescent; Drug Therapy, Combination; Ergotamine; Extremities; Heart Murmurs; Humans; Infections; Ischemia; Male; Paresthesia; Pharyngitis; Troleandomycin

1975
Risk of combination of tri-acetyl-oleandomycin and ergotamine tartrate.
    La Nouvelle presse medicale, 1976, Sep-11, Volume: 5, Issue:29

    Topics: Adult; Drug Therapy, Combination; Ergotamine; Ergotism; Female; Humans; Ischemia; Leg; Troleandomycin

1976
Precipitation of acute ergotism by triacetyloleandomycin.
    The New Zealand medical journal, 1969, Volume: 69, Issue:440

    Topics: Adult; Ergotamine; Ergotism; Humans; Liver; Male; Migraine Disorders; Tartrates; Troleandomycin

1969