Compounds > troleandomycin
Page last updated: 2024-09-05

troleandomycin and digitoxin

troleandomycin has been researched along with digitoxin in 4 studies

Compound Research Comparison

Studies
(troleandomycin)		Trials
(troleandomycin)		Recent Studies (post-2010)
(troleandomycin)		Studies
(digitoxin)		Trials
(digitoxin)		Recent Studies (post-2010) (digitoxin)
56926235,25990219

Protein Interaction Comparison

ProteinTaxonomytroleandomycin (IC50)digitoxin (IC50)
STAT3, partialHomo sapiens (human)0.7
Bile salt export pumpHomo sapiens (human)10
Sodium/potassium-transporting ATPase subunit alpha-1 Homo sapiens (human)0.008
Sodium/potassium-transporting ATPase subunit beta-1Homo sapiens (human)0.008
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.23
Sodium/potassium-transporting ATPase subunit alpha-3Homo sapiens (human)0.008
Sodium/potassium-transporting ATPase subunit beta-2Homo sapiens (human)0.008
Sodium/potassium-transporting ATPase subunit alpha-2Homo sapiens (human)0.008
Sodium/potassium-transporting ATPase subunit alpha-1Canis lupus familiaris (dog)0.008
Sodium/potassium-transporting ATPase subunit beta-3Homo sapiens (human)0.008
Sodium/potassium-transporting ATPase subunit gammaHomo sapiens (human)0.008
Sodium/potassium-transporting ATPase subunit alpha-4Homo sapiens (human)0.008
Solute carrier organic anion transporter family member 4C1Homo sapiens (human)0.12

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Eberhart, D; Fitzgerald, K; Parkinson, A1
Arlotto, MP; McKinney, MM; Parkinson, A; Sonderfan, AJ1

Other Studies

4 other study(ies) available for troleandomycin and digitoxin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Evidence for the involvement of a distinct form of cytochrome P450 3A in the oxidation of digitoxin by rat liver microsomes.
    Journal of biochemical toxicology, 1992,Spring, Volume: 7, Issue:1

    Topics: Aging; Analysis of Variance; Animals; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Digitoxin; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains; Sex Characteristics; Testosterone; Troleandomycin; Xenobiotics

1992
Digitoxin metabolism by liver microsomal cytochrome P-450 and UDP-glucuronosyltransferase and its role in the protection of rats from digitoxin toxicity by pregnenolone-16 alpha-carbonitrile.
    Archives of biochemistry and biophysics, 1986, Nov-15, Volume: 251, Issue:1

    Topics: Age Factors; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Digitoxin; Female; Glucuronosyltransferase; Male; Microsomes, Liver; Pregnenolone Carbonitrile; Rats; Sex Factors; Troleandomycin

1986