troleandomycin has been researched along with dapsone in 7 studies
| Studies (troleandomycin) | Trials (troleandomycin) | Recent Studies (post-2010) (troleandomycin) | Studies (dapsone) | Trials (dapsone) | Recent Studies (post-2010) (dapsone) |
|---|---|---|---|---|---|
| 569 | 26 | 23 | 5,116 | 379 | 862 |
| Protein | Taxonomy | troleandomycin (IC50) | dapsone (IC50) |
|---|---|---|---|
| Myeloperoxidase | Homo sapiens (human) | 0.42 | |
| Dihydrofolate reductase | Pneumocystis carinii | 1.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Kalhorn, TF; Kharasch, ED; Mitra, AK; Slattery, JT; Thummel, KE; Unadkat, JD | 1 |
| Moss, RB | 1 |
| Spector, SL | 1 |
2 review(s) available for troleandomycin and dapsone
| Article | Year |
|---|---|
Alternative pharmacotherapies for steroid-dependent asthma.
Topics: Adrenal Cortex Hormones; Asthma; Clinical Trials as Topic; Cyclosporine; Dapsone; Furosemide; Gold; Humans; Hydroxychloroquine; Magnesium Sulfate; Methotrexate; Treatment Outcome; Troleandomycin | 1995 |
Alternative treatments in the patient with intractable asthma.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Infective Agents; Antirheumatic Agents; Asthma; Cyclosporine; Dapsone; Humans; Hydroxychloroquine; Immunization, Passive; Immunosuppressive Agents; Methotrexate; Organogold Compounds; SRS-A; Troleandomycin | 1997 |
1 trial(s) available for troleandomycin and dapsone
| Article | Year |
|---|---|
Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo.
Topics: Adult; Alcohol Deterrents; Anti-Bacterial Agents; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dapsone; Disulfiram; Drug Interactions; Female; Humans; Hydroxylation; Leprostatic Agents; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Troleandomycin | 1995 |
4 other study(ies) available for troleandomycin and dapsone
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |