troleandomycin has been researched along with cycloguanil in 1 studies
| Studies (troleandomycin) | Trials (troleandomycin) | Recent Studies (post-2010) (troleandomycin) | Studies (cycloguanil) | Trials (cycloguanil) | Recent Studies (post-2010) (cycloguanil) |
|---|---|---|---|---|---|
| 569 | 26 | 23 | 231 | 16 | 37 |
| Protein | Taxonomy | troleandomycin (IC50) | cycloguanil (IC50) |
|---|---|---|---|
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 5.8 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | 2.985 | |
| Dihydrofolate reductase | Pneumocystis carinii | 0.45 | |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | 0.11 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, SL; Lu, AH; Ou-Yang, DS; Shu, Y; Wang, W; Zhou, HH | 1 |
1 other study(ies) available for troleandomycin and cycloguanil
| Article | Year |
|---|---|
In vitro proguanil activation to cycloguanil is mediated by CYP2C19 and CYP3A4 in adult Chinese liver microsomes.
Topics: Adult; Antimalarials; Aryl Hydrocarbon Hydroxylases; Asian People; Biotransformation; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Proguanil; Triazines; Troleandomycin | 2000 |