Compounds > troleandomycin
Page last updated: 2024-09-05

troleandomycin and buthionine sulfoximine

troleandomycin has been researched along with buthionine sulfoximine in 3 studies

Compound Research Comparison

Studies
(troleandomycin)		Trials
(troleandomycin)		Recent Studies (post-2010)
(troleandomycin)		Studies
(buthionine sulfoximine)		Trials
(buthionine sulfoximine)		Recent Studies (post-2010) (buthionine sulfoximine)
56926232,4608408

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Drobitch, RK; Kloss, KA; Svensson, CK1
Jiang, H; Ma, L; Shen, Q; Tian, Y; Wang, L; Yu, L; Zeng, S; Zhou, H; Zhou, Q; Zuo, M1
Fukami, T; Iida, A; Nakajima, M; Sasaki, E; Tsuneyama, K; Yano, A; Yokoi, T1

Other Studies

3 other study(ies) available for troleandomycin and buthionine sulfoximine

ArticleYear
Effect of glutathione depletion on the in vivo inhibition of drug metabolism by agents forming an inactive cytochrome P-450 Fe(II):metabolite complex. Studies with amiodarone and troleandomycin.
    Journal of pharmaceutical sciences, 1991, Volume: 80, Issue:3

    Topics: Amiodarone; Animals; Antimetabolites; Antipyrine; Buthionine Sulfoximine; Cytochrome P-450 Enzyme System; Glutathione; Liver; Male; Maleates; Methionine Sulfoximine; Pharmaceutical Preparations; Rats; Rats, Inbred Strains; Troleandomycin

1991
Demethylation of neferine in human liver microsomes and formation of quinone methide metabolites mediated by CYP3A4 accentuates its cytotoxicity.
    Chemico-biological interactions, 2014, Dec-05, Volume: 224

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Benzylisoquinolines; Buthionine Sulfoximine; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dogs; Glutathione; Hep G2 Cells; Humans; Indolequinones; Ketoconazole; Kinetics; Madin Darby Canine Kidney Cells; Microsomes, Liver; Troleandomycin

2014
Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2015, Volume: 43, Issue:7

    Topics: Alanine Transaminase; Animals; Anti-Bacterial Agents; Antifungal Agents; Buthionine Sulfoximine; Carbamazepine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Enzyme Induction; Enzyme Inhibitors; Glutathione; Hydroxylation; Ketoconazole; Liver; Male; Microsomes, Liver; Rats; Rats, Inbred F344; Troleandomycin

2015