troleandomycin has been researched along with bromocriptine in 5 studies
| Studies (troleandomycin) | Trials (troleandomycin) | Recent Studies (post-2010) (troleandomycin) | Studies (bromocriptine) | Trials (bromocriptine) | Recent Studies (post-2010) (bromocriptine) |
|---|---|---|---|---|---|
| 569 | 26 | 23 | 7,121 | 727 | 499 |
| Protein | Taxonomy | troleandomycin (IC50) | bromocriptine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.532 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 2.4 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 2.4996 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.015 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0016 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 2.281 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.035 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.52 | |
| D | Rattus norvegicus (Norway rat) | 0.0279 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0279 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0056 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.514 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 2.889 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.514 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.514 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.03 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0279 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.036 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.532 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.0056 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0279 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0006 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0083 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.022 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0279 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dantzig, AH; Ekins, S; Kim, RB; Lan, LB; Leake, BF; Schuetz, EG; Schuetz, JD; Shepard, RL; Wikel, JH; Winter, MA; Wrighton, SA; Yasuda, K | 1 |
| Furuya, K; Lan, LB; Sanglard, D; Schuetz, EG; Schuetz, JD; Yasuda, K | 1 |
| Pratim Roy, P; Roy, K | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fukui, Y; Matsubayashi, K; Matsumoto, H | 1 |
5 other study(ies) available for troleandomycin and bromocriptine
| Article | Year |
|---|---|
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Ergonovine; Fluoxetine; Humans; Models, Molecular; Oxytocics; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Swine; Transfection; Vinblastine | 2002 |
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroergocryptine; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; Mice; Mice, Knockout; Microsomes, Liver; Oxidoreductases, N-Demethylating; Recombinant Proteins; Reserpine; Swine; Tissue Distribution; Transfection; Vinblastine | 2002 |
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques.
Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Contribution of cytochrome P450 3A pathway to bromocriptine metabolism and effects of ferrous iron and hypoxia-re-oxygenation on its elimination in the perfused rat liver.
Topics: Amitrole; Animals; Aryl Hydrocarbon Hydroxylases; Body Fluid Compartments; Bromocriptine; Cell Hypoxia; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Ferrous Compounds; Liver; Male; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Oxygen; Perfusion; Rats; Rats, Wistar; Troleandomycin | 1997 |