Page last updated: 2024-09-05

troleandomycin and amlodipine

troleandomycin has been researched along with amlodipine in 3 studies

Compound Research Comparison

Studies
(troleandomycin)
Trials
(troleandomycin)
Recent Studies (post-2010)
(troleandomycin)
Studies
(amlodipine)
Trials
(amlodipine)
Recent Studies (post-2010) (amlodipine)
56926234,2001,5041,671

Protein Interaction Comparison

ProteinTaxonomytroleandomycin (IC50)amlodipine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)1.2
Potassium channel subfamily K member 2Homo sapiens (human)0.4
Alpha-2A adrenergic receptorHomo sapiens (human)0.602
Alpha-2C adrenergic receptorHomo sapiens (human)1.8
5-hydroxytryptamine receptor 6Homo sapiens (human)2.898
Sodium-dependent dopamine transporter Homo sapiens (human)5.521
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)2.7
Potassium channel subfamily K member 2 Bos taurus (cattle)0.43

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Kim, EJ; Kwon, JW; Lee, JH; Lee, MG; Yoo, M1

Other Studies

3 other study(ies) available for troleandomycin and amlodipine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Negligible pharmacokinetic interaction between oral DA-8159, a new erectogenic, and amlodipine in rats.
    Biopharmaceutics & drug disposition, 2006, Volume: 27, Issue:3

    Topics: Administration, Oral; Amlodipine; Animals; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Inhibitors; Feces; Gastrointestinal Tract; Injections, Intraperitoneal; Injections, Intravenous; Male; Penile Erection; Phosphodiesterase Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Sulfonamides; Time Factors; Troleandomycin; Tyrosine

2006