Compounds > troleandomycin
Page last updated: 2024-09-05

troleandomycin and aflatoxin b1

troleandomycin has been researched along with aflatoxin b1 in 7 studies

Compound Research Comparison

Studies
(troleandomycin)		Trials
(troleandomycin)		Recent Studies (post-2010)
(troleandomycin)		Studies
(aflatoxin b1)		Trials
(aflatoxin b1)		Recent Studies (post-2010) (aflatoxin b1)
56926234,532491,715

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Eaton, DL; Eddy, AC; Parkinson, A; Ramsdell, HS1
Guengerich, FP; Shimada, T1
Halvorson, MR; Parkinson, A; Phillips, TD; Safe, SH1
Hashimoto, H; Itoh, S; Kamataki, T; Nakagawa, T; Sawada, M; Yokoi, T1
Eaton, DL; Gallagher, EP; Kunze, KL; Stapleton, PL; Wienkers, LC1

Other Studies

7 other study(ies) available for troleandomycin and aflatoxin b1

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Bioactivation of aflatoxin B1 by human liver microsomes: role of cytochrome P450 IIIA enzymes.
    Toxicology and applied pharmacology, 1991, Volume: 108, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Benzoflavones; Biotransformation; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Microsomes, Liver; Nifedipine; Oxidation-Reduction; Troleandomycin

1991
Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Antibodies; Benzoflavones; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Immunochemistry; Microsomes, Liver; Mixed Function Oxygenases; Nifedipine; Oxidation-Reduction; Sterigmatocystin; Troleandomycin

1989
Aflatoxin B1 hydroxylation by the pregnenolone-16 alpha-carbonitrile-inducible form of rat liver microsomal cytochrome P-450.
    Carcinogenesis, 1988, Volume: 9, Issue:11

    Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Hydroxylation; Microsomes, Liver; Mutagenicity Tests; Pregnenolone Carbonitrile; Rats; Sex Factors; Troleandomycin

1988
Fetus-specific CYP3A7 and adult-specific CYP3A4 expressed in Chinese hamster CHL cells have similar capacity to activate carcinogenic mycotoxins.
    Cancer research, 1995, Feb-15, Volume: 55, Issue:4

    Topics: Adult; Aflatoxin B1; Aging; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Biotransformation; Carcinogens; Cell Line; Clone Cells; Cricetinae; Cricetulus; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Drug Interactions; Fetus; Gene Expression; Guinea Pigs; Humans; Mycotoxins; Sensitivity and Specificity; Transfection; Transformation, Genetic; Troleandomycin

1995
Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1.
    Cancer research, 1994, Jan-01, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Aflatoxin B1; Biotransformation; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Female; Humans; Hydroxylation; Lymphocytes; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Oxidation-Reduction; Oxidoreductases; Theophylline; Troleandomycin

1994