Compounds > troglitazone
Page last updated: 2024-08-16

troglitazone and troglitazone sulfate

troglitazone has been researched along with troglitazone sulfate in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Funk, C; Gasser, R; Jehle, L; Lazendic, M; Pantze, M; Ponelle, C; Scheuermann, G1
Goto, A; Nakajima, M; Nezu, J; Nozawa, T; Sugiura, S; Tamai, I; Tsuji, A; Yokoi, T1
Chan, EC; Chui, WK; Ho, HK; New, LS; Saha, S1
Abrahamsson, A; Foster, JR; Jacobsen, M; Pickup, K; Randall, K; Samuelsson, K; Sarda, S; Weidolf, L; Wilson, I1
Brouwer, KL; Köck, K; Pfeifer, ND; Yang, K1
Boisbrun, M; Flament, S; Geoffroy, M; Grandemange, S; Grillier-Vuissoz, I; Hupont, S; Kleinclauss, A; Kuntz, S1
Chijiwa, H; Ito, S; Kamimura, H; Okuzono, T; Suemizu, H; Yamamoto, Y; Yamazaki, H1

Other Studies

7 other study(ies) available for troglitazone and troglitazone sulfate

ArticleYear
Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile salt
    Toxicology, 2001, Oct-05, Volume: 167, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biliary Tract; Biological Transport, Active; Cholestasis, Intrahepatic; Chromans; Cytosol; Female; Glyburide; Hypoglycemic Agents; Liver; Male; Rats; Rats, Wistar; Sex Factors; Sulfates; Taurocholic Acid; Thiazoles; Thiazolidinediones; Troglitazone

2001
Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: implications for understanding troglitazone hepatotoxicity.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:3

    Topics: Biological Transport, Active; Chemical and Drug Induced Liver Injury; Chromans; Cloning, Molecular; DNA, Complementary; Estrone; Hepatocytes; Humans; Hypoglycemic Agents; Molecular Sequence Data; Oocytes; Organic Anion Transporters; Pioglitazone; Protein Binding; Quinones; Reverse Transcriptase Polymerase Chain Reaction; Thiazolidinediones; Troglitazone

2004
Direct toxicity effects of sulfo-conjugated troglitazone on human hepatocytes.
    Toxicology letters, 2010, Jun-02, Volume: 195, Issue:2-3

    Topics: Cell Line; Cell Survival; Chromans; Glutathione; Hepatocytes; Humans; Hypoglycemic Agents; Oxidative Stress; Protein Carbonylation; Sulfotransferases; Sulfuric Acid Esters; Thiazolidinediones; Troglitazone

2010
Troglitazone metabolism and transporter effects in chimeric mice: a comparison between chimeric humanized and chimeric murinized FRG mice.
    Xenobiotica; the fate of foreign compounds in biological systems, 2014, Volume: 44, Issue:2

    Topics: Animals; Bile; Blood Chemical Analysis; Chromans; Hepatocytes; Humans; Hydrolases; Inactivation, Metabolic; Liver; Male; Membrane Transport Proteins; Mice; Mice, Transgenic; Sulfuric Acid Esters; Thiazolidinediones; Transplantation Chimera; Troglitazone

2014
Species differences in hepatobiliary disposition of taurocholic acid in human and rat sandwich-cultured hepatocytes: implications for drug-induced liver injury.
    The Journal of pharmacology and experimental therapeutics, 2015, Volume: 353, Issue:2

    Topics: Adult; Animals; Bile Ducts; Biological Transport; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chromans; Dehydroepiandrosterone; Female; Hepatocytes; Humans; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Rats; Species Specificity; Sulfuric Acid Esters; Taurocholic Acid; Thiazolidinediones; Troglitazone

2015
Pro-apoptotic effect of Δ2-TGZ in "claudin-1-low" triple-negative breast cancer cells: involvement of claudin-1.
    Breast cancer research and treatment, 2017, Volume: 165, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Claudin-1; Female; Gene Expression Regulation; Humans; Protein Transport; Sulfuric Acid Esters; Thiazolidinediones; Triple Negative Breast Neoplasms; Troglitazone

2017
Human plasma concentration-time profiles of troglitazone and troglitazone sulfate simulated by in vivo experiments with chimeric mice with humanized livers and semi-physiological pharmacokinetic modeling.
    Drug metabolism and pharmacokinetics, 2020, Volume: 35, Issue:6

    Topics: Animals; Computer Simulation; Hepatocytes; Humans; Hypoglycemic Agents; Liver; Male; Metabolic Detoxication, Phase II; Mice, Transgenic; Models, Biological; Sulfuric Acid Esters; Transplantation Chimera; Troglitazone

2020