troglitazone has been researched along with leptin in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (29.63) | 18.2507 |
| 2000's | 17 (62.96) | 29.6817 |
| 2010's | 2 (7.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caro, JF; Considine, RV; Nolan, JJ; Nyce, MR; Olefsky, JM | 1 |
| Dunaif, A; Flier, JS; Mantzoros, CS | 1 |
| Koyama, K; Lee, Y; Shimabukuro, M; Unger, RH | 1 |
| Burant, CF; Davidson, NO; Graves, RA; Hirano, K; Lohmiller, J; Lukens, J; Ross, S; Sreenan, S; Tai, TA | 1 |
| Akanuma, Y; Fujiwara, T; Horikoshi, H; Iwamoto, K; Kadowaki, T; Mori, Y; Okuno, A; Tamemoto, H; Tobe, K; Ueki, K; Umesono, K; Yazaki, Y | 1 |
| Kobayashi, I; Mori, M; Sato, N; Shimizu, H; Shimomura, Y; Tsuchiya, T | 1 |
| Addya, S; Boden, G; Murer, E; Sinha, D | 1 |
| Collier, G; Zimmet, P | 1 |
| Higa, M; Kakuma, T; Lee, Y; Pan, W; Shimomura, I; Unger, RH; Wang, Zw | 1 |
| Considine, RV; Fawcett, RL; Huse, J; Inman, M; Jones, R; Kogon, BE; Waechter, AS; Williams, LB; Zhang, P | 1 |
| Andersen, RN; Bahouth, SW; Buffington, C; Cowan, GS; Fain, JN; Pouncey, L | 1 |
| Gruenewald, DA; Marck, BT; Matsumoto, AM; Naai, MA; Wolden-Hanson, T | 1 |
| Doyle, PJ; Naderali, EK; Pickavance, LC; Wilding, JP; Williams, G | 1 |
| Maher, J | 1 |
| Chang, CT; Chen, CC; Chen, RH; Sheen, LY; Shih, HC; Wang, HJ; Wang, TY | 1 |
| Iwamoto, Y; Kanamuro, R; Maruyama, S; Teno, S; Yanagisawa, K | 1 |
| Marck, BT; Matsumoto, AM; Wolden-Hanson, T | 1 |
| Brant, BP; Garvey, WT; Kennedy, A; Rogers, NL; Wallace, P; Willi, SM | 1 |
| Ganaway, E; Garvey, WT; Kennedy, A; Rogers, NL; Wallace, P; Willi, SM | 1 |
| Kakuma, T; Lee, Y; Unger, RH | 1 |
| Bungenstock, A; Czupalla, C; Eilers, F; Fleck, E; Goetze, S; Graf, K; Gräfe, M; Kintscher, U; Law, RE; Nürnberg, B; Spencer-Hänsch, C; Stawowy, P | 1 |
| Fujita, H; Fujita, T; Fukumoto, S; Nakano, T; Takeuchi, Y; Watanabe, S | 1 |
| Agarwal, AK; Duplomb, L; Lee, Y; Park, BH; Takaishi, K; Unger, RH; Wang, MY | 1 |
| Caldefie-Chézet, F; Enreille-Leger, A; Poulin, A; Vasson, MP | 1 |
| Blum, WF; Hauner, H; Skurk, T; van Harmelen, V | 1 |
| Noh, M | 1 |
| Cristino, L; Di Marzo, V; Imperatore, R; Martella, A; Morello, G; Palomba, L; Piscitelli, F; Silvestri, C | 1 |
1 review(s) available for troglitazone and leptin
| Article | Year |
|---|---|
Clinical efficacy of metformin against insulin resistance parameters: sinking the iceberg.
Topics: Animals; Blood Glucose; Cardiovascular Diseases; Chromans; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Male; Metformin; Rats; Risk Factors; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
5 trial(s) available for troglitazone and leptin
| Article | Year |
|---|---|
Leptin concentrations in the polycystic ovary syndrome.
Topics: Adult; Body Mass Index; Chromans; Double-Blind Method; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Obesity; Osmolar Concentration; Polycystic Ovary Syndrome; Proteins; Thiazoles; Thiazolidinediones; Troglitazone | 1997 |
Troglitazone reduces plasma leptin concentration but increases hunger in NIDDM patients.
Topics: Blood Glucose; Body Mass Index; Chromans; Diabetes Mellitus, Type 2; Energy Intake; Feeding Behavior; Glycated Hemoglobin; Humans; Hunger; Hypoglycemic Agents; Insulin Resistance; Islets of Langerhans; Leptin; Lipids; Middle Aged; Proteins; Thiazoles; Thiazolidinediones; Troglitazone | 1998 |
Serum leptin level as an indicator to predict the clinical efficacy of troglitazone in patients with type 2 diabetes mellitus.
Topics: Biomarkers; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Fasting; Female; Glycated Hemoglobin; Homeostasis; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Male; Middle Aged; Models, Biological; Predictive Value of Tests; Regression Analysis; Thiazoles; Thiazolidinediones; Time Factors; Troglitazone | 2001 |
Troglitazone antagonizes metabolic effects of glucocorticoids in humans: effects on glucose tolerance, insulin sensitivity, suppression of free fatty acids, and leptin.
Topics: Adult; Chromans; Dexamethasone; Drug Interactions; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucocorticoids; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin Resistance; Leptin; Male; Middle Aged; Thiazoles; Thiazolidinediones; Troglitazone | 2002 |
Decrease in serum leptin by troglitazone is associated with preventing bone loss in type 2 diabetic patients.
Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Bone Density; Chromans; Collagen; Collagen Type I; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Leptin; Lumbar Vertebrae; Male; Middle Aged; Osteoporosis; Peptides; Prospective Studies; Thiazolidinediones; Troglitazone | 2003 |
21 other study(ies) available for troglitazone and leptin
| Article | Year |
|---|---|
Effect of troglitazone on leptin production. Studies in vitro and in human subjects.
Topics: Adipocytes; Adult; Animals; Blood Glucose; Cells, Cultured; Chromans; Fasting; Female; Glucose; Humans; Hyperinsulinism; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Leptin; Male; Middle Aged; Obesity; Protein Biosynthesis; Proteins; Thiazoles; Thiazolidinediones; Troglitazone | 1996 |
Leptin- or troglitazone-induced lipopenia protects islets from interleukin 1beta cytotoxicity.
Topics: Animals; Cell Survival; Cells, Cultured; Chromans; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Gene Transfer Techniques; Interleukin-1; Islets of Langerhans; Leptin; Lipids; Nitric Oxide; Obesity; Proteins; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone | 1997 |
Troglitazone action is independent of adipose tissue.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Cholesterol; Chromans; Diabetes Mellitus, Type 2; Eating; Fatty Acids; Glycogen; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Leptin; Lipoproteins, LDL; Lipoproteins, VLDL; Mice; Mice, Transgenic; Organ Size; Proteins; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Triglycerides; Troglitazone | 1997 |
Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats.
Topics: Adipocytes; Adipose Tissue; Animals; Apoptosis; Blood Glucose; Blotting, Northern; Body Weight; Chromans; DNA; DNA, Complementary; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Male; Mesentery; Polymerase Chain Reaction; Proteins; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Retroperitoneal Space; RNA; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Triglycerides; Troglitazone; Tumor Necrosis Factor-alpha | 1998 |
15-Deoxy-delta(12,14) prostaglandin J2: a putative endogenous promoter of adipogenesis suppresses the ob gene.
Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Chromans; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; Indomethacin; Leptin; Monosaccharide Transport Proteins; Muscle Proteins; Nuclear Proteins; Obesity; Prostaglandin D2; Proteins; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 1999 |
Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets.
Topics: Adenoviridae; Animals; CCAAT-Enhancer-Binding Proteins; Chromans; DNA-Binding Proteins; Genetic Vectors; Hyperinsulinism; Hypolipidemic Agents; Islets of Langerhans; Leptin; Liver; Male; Nuclear Proteins; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Up-Regulation | 2000 |
Leptin production in adipocytes from morbidly obese subjects: stimulation by dexamethasone, inhibition with troglitazone, and influence of gender.
Topics: Adipocytes; Cells, Cultured; Chromans; Dexamethasone; Female; Gene Expression Regulation; Humans; Leptin; Male; Obesity, Morbid; Omentum; Reverse Transcriptase Polymerase Chain Reaction; Sex Characteristics; Thiazoles; Thiazolidinediones; Transcription, Genetic; Troglitazone | 2000 |
Regulation of leptin release by troglitazone in human adipose tissue.
Topics: Adipose Tissue; Adult; Aged; Chromans; Culture Techniques; Dexamethasone; Female; Humans; Hypoglycemic Agents; Insulin; Leptin; Male; Middle Aged; Prostaglandins; RNA, Messenger; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Aging and the neuroendocrine regulation of reproduction and body weight.
Topics: Aging; Animals; Arcuate Nucleus of Hypothalamus; Body Composition; Body Weight; Chromans; Eating; Gene Expression Regulation, Developmental; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Humans; Hypoglycemic Agents; Insulin; Leptin; Male; Models, Animal; Neuropeptide Y; Neurosecretory Systems; Pituitary Gland; Rats; Rats, Inbred BN; Reproduction; RNA, Messenger; Testis; Thiazoles; Thiazolidinediones; Troglitazone; Weight Gain | 2000 |
Troglitazone corrects metabolic changes but not vascular dysfunction in dietary-obese rats.
Topics: Acetylcholine; Animals; Blood Glucose; Body Weight; Chromans; Diet; Dose-Response Relationship, Drug; Endothelium, Vascular; Energy Metabolism; Fatty Acids, Nonesterified; Female; Hypoglycemic Agents; In Vitro Techniques; Insulin; Leptin; Mesenteric Arteries; Nitroprusside; Norepinephrine; Obesity; Potassium Chloride; Rats; Rats, Wistar; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Antidiabetic treatment for NASH?
Topics: Animals; CCAAT-Enhancer-Binding Proteins; Chromans; Diabetes Mellitus; DNA-Binding Proteins; Fatty Liver; Hepatitis; Hypoglycemic Agents; Islets of Langerhans; Leptin; Liver; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |
Comparison of the metabolic effects of metformin and troglitazone on fructose-induced insulin resistance in male Sprague-Dawley rats.
Topics: Animals; Chromans; Fatty Acids, Nonesterified; Fructose; Hypoglycemic Agents; Insulin Resistance; Leptin; Male; Metformin; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones; Troglitazone | 2001 |
Troglitazone treatment of aging Brown Norway rats improves food intake and weight gain after fasting without increasing hypothalamic NPY gene expression.
Topics: Aging; Animals; Body Composition; Chromans; Eating; Fasting; Gene Expression; Hypoglycemic Agents; Hypothalamus; In Situ Hybridization; Insulin; Leptin; Male; Neuropeptide Y; Protein Precursors; Rats; Rats, Inbred BN; RNA, Messenger; Thiazoles; Thiazolidinediones; Troglitazone; Weight Gain | 2002 |
Effective use of thiazolidinediones for the treatment of glucocorticoid-induced diabetes.
Topics: Administration, Oral; Adult; Biomarkers; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Fructosamine; Glucocorticoids; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Leptin; Middle Aged; Prednisone; Thiazoles; Thiazolidinediones; Troglitazone | 2002 |
Effects of leptin, troglitazone, and dietary fat on stearoyl CoA desaturase.
Topics: Adenoviridae; Animals; Antioxidants; Chromans; Dietary Fats; DNA, Complementary; Down-Regulation; Fats; Leptin; Linear Models; Liver; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Rats, Zucker; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Stearoyl-CoA Desaturase; Thiazoles; Thiazolidinediones; Troglitazone; Up-Regulation | 2002 |
Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands.
Topics: Androstadienes; Cell Line; Cell Movement; Chemotaxis; Chromans; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Leptin; Ligands; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Suppressor Proteins; Wortmannin | 2002 |
Increased expression and activity of 11beta-HSD-1 in diabetic islets and prevention with troglitazone.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Animals, Genetically Modified; Blotting, Western; Chromans; Cushing Syndrome; Diabetes Mellitus, Experimental; Fatty Acids; Glucose; Hyperglycemia; Hypoglycemic Agents; Islets of Langerhans; Leptin; Microsomes, Liver; Obesity; Oleic Acid; Palmitates; Phenotype; Prednisone; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazolidinediones; Troglitazone | 2004 |
Troglitazone reduces leptinemia during experimental dexamethasone-induced stress.
Topics: Adipocytes; Adipose Tissue; Animals; Anorexia; Blood Glucose; Body Weight; Chemical and Drug Induced Liver Injury; Chromans; Dexamethasone; Disease Models, Animal; Eating; Glucocorticoids; Hypoglycemic Agents; Insulin; Leptin; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Physiological; Thiazolidinediones; Troglitazone | 2005 |
Angiotensin II promotes leptin production in cultured human fat cells by an ERK1/2-dependent pathway.
Topics: Adipocytes; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Butadienes; Cells, Cultured; Chromans; Drug Interactions; Extracellular Signal-Regulated MAP Kinases; Female; Fibrinolytic Agents; Humans; Leptin; MAP Kinase Signaling System; Nitriles; Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Thiazolidinediones; Troglitazone | 2005 |
Interleukin-17A increases leptin production in human bone marrow mesenchymal stem cells.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adipogenesis; Adiponectin; Bone Marrow Cells; Cell Differentiation; Chromans; Dexamethasone; Glucocorticoids; Humans; Hypoglycemic Agents; Insulin; Interleukin-17; Leptin; Mesenchymal Stem Cells; Osteoblasts; Osteogenesis; Thiazolidinediones; Troglitazone; Up-Regulation | 2012 |
Negative Regulation of Leptin-induced Reactive Oxygen Species (ROS) Formation by Cannabinoid CB1 Receptor Activation in Hypothalamic Neurons.
Topics: Adipocytes; Animals; Animals, Newborn; Arachidonic Acids; Benzamides; Body Weight; Cannabinoids; Catalase; Cells, Cultured; Chromans; Endocannabinoids; Gene Expression Regulation; Gene Silencing; Hydrolysis; Hypothalamus; Leptin; Mice; Mice, Inbred C57BL; Neurons; PPAR alpha; PPAR gamma; Pyridines; Reactive Oxygen Species; Receptor, Cannabinoid, CB1; RNA, Small Interfering; Thiazolidinediones; Troglitazone | 2015 |