Compounds > troglitazone
Page last updated: 2024-08-16

troglitazone and l-165041

troglitazone has been researched along with l-165041 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Brown, PJ; Henke, BR; Sternbach, DD; Willson, TM1
Altieri, F; Azzariti, A; Cervoni, L; Crestani, M; Di Giovanni, C; Fracchiolla, G; Gilardi, F; Giudici, M; Guerrini, U; Laghezza, A; Lavecchia, A; Loiodice, F; Mitro, N; Montanari, R; Paradiso, A; Piemontese, L; Pochetti, G; Porcelli, L; Simone, GM; Tortorella, P1
Kiem, PV; Kim, YH; Minh, CV; Ngan, NT; Quang, TH; Song, SB; Tai, BH; Thao, NP1
Anh, Hle T; Choi, CW; Kiem, PV; Kim, YH; Luyen, BT; Minh, CV; Ngan, NT; Nhiem, NX; Quang, TH; Tai, BH; Thao, NP; Yang, SY; Yen, PH1
Chen, S; Chen, X; Gong, Z; Guo, F; He, H; Hou, L; Jiang, Z; Li, H; Li, J; Liu, X; Liu, Z; Long, C; Shen, L; Wang, J; Xu, D; Yuan, Z; Zhang, J; Zhang, X1
Choi, S; Fang, S; Kim, DK; Kim, I; Krishnaiah, M; Kwon, Y; Lee, HJ; Lee, Y; Oh, AR; Park, J; Park, S; Sankham, MR; Shim, S; Shin, I; Vu, TNL1
Chopra, B; Georgopoulos, NT; Hinley, J; Nicholl, A; Oleksiewicz, MB; Southgate, J1
Chen, CY; Hsu, CY; Jian, JH; Leu, JG; Liang, YJ; Shih, CY1

Reviews

1 review(s) available for troglitazone and l-165041

ArticleYear
The PPARs: from orphan receptors to drug discovery.
    Journal of medicinal chemistry, 2000, Feb-24, Volume: 43, Issue:4

    Topics: Animals; Diabetes Mellitus; Drug Design; Humans; Hyperlipidemias; Hypertension; Inflammation; Ligands; Models, Molecular; Neoplasms; Nuclear Proteins; Obesity; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2000

Other Studies

7 other study(ies) available for troglitazone and l-165041

ArticleYear
Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Adipocytes; Animals; Antineoplastic Agents; Benzoxazoles; Body Weight; Calorimetry; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Partial Agonism; Drug Screening Assays, Antitumor; Fibric Acids; Fibroblasts; Gene Expression Profiling; Humans; Insulin Resistance; Intra-Abdominal Fat; Liver; Mice; Mice, Inbred C57BL; Models, Molecular; PPAR alpha; PPAR gamma; Propionates; Stereoisomerism; Structure-Activity Relationship; Urea

2012
Anti-inflammatory and PPAR transactivational effects of secondary metabolites from the roots of Asarum sieboldii.
    Bioorganic & medicinal chemistry letters, 2012, Apr-01, Volume: 22, Issue:7

    Topics: Anti-Inflammatory Agents; Asarum; Cyclooxygenase 2; Dose-Response Relationship, Drug; Furans; Hep G2 Cells; Humans; Inflammation; Magnetic Resonance Spectroscopy; Mass Spectrometry; NF-kappa B; Nitric Oxide Synthase Type II; Phenols; Plant Roots; PPAR alpha; Republic of Korea; Transcription, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha

2012
Diarylheptanoid glycosides from Tacca plantaginea and their effects on NF-κB activation and PPAR transcriptional activity.
    Bioorganic & medicinal chemistry letters, 2012, Nov-01, Volume: 22, Issue:21

    Topics: Antimetabolites; Diarylheptanoids; Dioscoreaceae; Enzyme Activation; Glycosides; Hep G2 Cells; Humans; Magnetic Resonance Spectroscopy; Methanol; Molecular Structure; NF-kappa B; Peroxisome Proliferator-Activated Receptors; Transcription, Genetic

2012
Discovery of a Novel Selective Dual Peroxisome Proliferator-Activated Receptor α/δ Agonist for the Treatment of Primary Biliary Cirrhosis.
    ACS medicinal chemistry letters, 2019, Jul-11, Volume: 10, Issue:7

    Topics:

2019
Discovery of (
    Journal of medicinal chemistry, 2022, 07-28, Volume: 65, Issue:14

    Topics: Acrylates; Animals; Bile Acids and Salts; Esters; Intestines; Liver; Mice; Non-alcoholic Fatty Liver Disease; Rats; Receptors, Cytoplasmic and Nuclear

2022
Structurally diverse peroxisome proliferator-activated receptor agonists induce apoptosis in human uro-epithelial cells by a receptor-independent mechanism involving store-operated calcium channels.
    Cell proliferation, 2009, Volume: 42, Issue:5

    Topics: Apoptosis; Calcium; Calcium Channels; Caspase 3; Caspase 9; Cell Division; Cells, Cultured; Chromans; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Fenofibrate; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Membrane Potential, Mitochondrial; Oxazines; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptors; Phenoxyacetates; Phenylpropionates; Rosiglitazone; Thiazolidinediones; Troglitazone; Urothelium

2009
L-165,041, troglitazone and their combination treatment to attenuate high glucose-induced receptor for advanced glycation end products (RAGE) expression.
    European journal of pharmacology, 2013, Sep-05, Volume: 715, Issue:1-3

    Topics: Apoptosis; Chromans; Cytokines; Drug Interactions; Gene Expression Regulation; Glucose; HEK293 Cells; Humans; Hyperglycemia; NF-kappa B; Oxidative Stress; Phenoxyacetates; PPAR delta; PPAR gamma; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Thiazolidinediones; Troglitazone

2013