Compounds > troglitazone
Page last updated: 2024-08-16

troglitazone and gw 1929

troglitazone has been researched along with gw 1929 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Blanchard, SG; Brackeen, MF; Brown, KK; Cobb, JE; Collins, JL; Harrington, WW; Hashim, MA; Henke, BR; Hull-Ryde, EA; Kaldor, I; Kliewer, SA; Lake, DH; Leesnitzer, LM; Lehmann, JM; Lenhard, JM; Miller, JF; Mook, RA; Noble, SA; Oliver, W; Orband-Miller, LA; Parks, DJ; Plunket, KD; Szewczyk, JR; Willson, TM1
Brown, PJ; Henke, BR; Sternbach, DD; Willson, TM1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Ahn, S; Cheong, JH; Jacobson, KA; Jeong, LS; Jin, SH; Kim, G; Kim, HJ; Kim, J; Lee, E; Lee, M; Noh, M; Yu, J1
Ahn, S; An, S; Choi, H; Jeong, LS; Ko, H; Noh, M; Pyo, JJ; Shin, JC; Yu, J1
Ahn, S; An, S; Choi, WJ; Gong, J; Hwang, SY; Jang, H; Kim, H; Ko, H; Kwak, SY; Noh, M; Oh, S; Park, IG1
Adkison, K; Binz, JG; Blanchard, SG; Brown, HR; Brown, KK; Cobb, JE; Faison, W; Harrington, WW; Hashim, MA; Henke, BR; Kaldor, I; Kliewer, SA; Lehmann, JM; Lenhard, JM; Menius, JA; Mook, R; Noble, SA; Novak, PJ; Oliver, WO; Parks, DJ; Plunket, KD; Tong, WQ; Willson, TM1
Chang, KC; Kim, HJ; Kim, YM; Lee, JH; Nizamutdinova, IT; Seo, HG1

Reviews

1 review(s) available for troglitazone and gw 1929

ArticleYear
The PPARs: from orphan receptors to drug discovery.
    Journal of medicinal chemistry, 2000, Feb-24, Volume: 43, Issue:4

    Topics: Animals; Diabetes Mellitus; Drug Design; Humans; Hyperlipidemias; Hypertension; Inflammation; Ligands; Models, Molecular; Neoplasms; Nuclear Proteins; Obesity; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2000

Other Studies

7 other study(ies) available for troglitazone and gw 1929

ArticleYear
N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents.
    Journal of medicinal chemistry, 1998, Dec-03, Volume: 41, Issue:25

    Topics: Administration, Oral; Aminopyridines; Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; DNA-Binding Proteins; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Ligands; Lipids; Male; Mice; Oxazoles; Propionates; Radioligand Assay; Rats; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Stereoisomerism; Structure-Activity Relationship; Transcription Factors; Transfection; Tyrosine

1998
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Polypharmacology of N
    Journal of medicinal chemistry, 2017, 09-14, Volume: 60, Issue:17

    Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adiponectin; Animals; Cell Line; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Insulin Resistance; Ligands; Male; Mice; Mice, Inbred C57BL; Polypharmacology; PPAR delta; PPAR gamma; Receptor, Adenosine A3

2017
Selenium bioisosteric replacement of adenosine derivatives promoting adiponectin secretion increases the binding affinity to peroxisome proliferator-activated receptor δ.
    Bioorganic & medicinal chemistry, 2020, 01-01, Volume: 28, Issue:1

    Topics: Adenosine; Adiponectin; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Mesenchymal Stem Cells; Molecular Docking Simulation; Molecular Structure; PPAR delta; Selenium; Structure-Activity Relationship

2020
Galangin 3-benzyl-5-methylether derivatives function as an adiponectin synthesis-promoting peroxisome proliferator-activated receptor γ partial agonist.
    Bioorganic & medicinal chemistry, 2022, 01-15, Volume: 54

    Topics: Adiponectin; Cells, Cultured; Dose-Response Relationship, Drug; Flavonoids; Humans; Hypoglycemic Agents; Molecular Docking Simulation; Molecular Structure; PPAR gamma; Structure-Activity Relationship

2022
A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat.
    Diabetes, 1999, Volume: 48, Issue:7

    Topics: Animals; Benzophenones; Chromans; Clone Cells; Diabetes Mellitus, Experimental; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Immunohistochemistry; Logistic Models; Obesity; Phenotype; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tyrosine

1999
Carbon monoxide (from CORM-2) inhibits high glucose-induced ICAM-1 expression via AMP-activated protein kinase and PPAR-gamma activations in endothelial cells.
    Atherosclerosis, 2009, Volume: 207, Issue:2

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Anilides; Anti-Inflammatory Agents; Benzophenones; Carbon Monoxide; Cell Adhesion; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Enzyme Activators; Glucose; Humans; Hypoglycemic Agents; Intercellular Adhesion Molecule-1; Organometallic Compounds; PPAR gamma; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Ribonucleotides; Signal Transduction; Thiazolidinediones; Time Factors; Transfection; Troglitazone; Tyrosine

2009