troglitazone has been researched along with glyburide in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (27.27) | 18.2507 |
| 2000's | 12 (36.36) | 29.6817 |
| 2010's | 11 (33.33) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Funk, C; Gasser, R; Jehle, L; Lazendic, M; Pantze, M; Ponelle, C; Scheuermann, G | 1 |
| Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ | 1 |
| Bergström, CA; Hubatsch, I; Johansson, K; Wassvik, CM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ahn, S; Cheong, JH; Jacobson, KA; Jeong, LS; Jin, SH; Kim, G; Kim, HJ; Kim, J; Lee, E; Lee, M; Noh, M; Yu, J | 1 |
| Ahn, S; An, S; Hwang, J; Hyun, S; Lee, J; Lee, M; Noh, M | 1 |
| Norman, BH | 1 |
| Horikoshi, H; Ishida, H; Kato, S; Masuda, K; Miura, T; Okamoto, Y; Seino, Y; Tsuda, K; Tsuura, Y | 1 |
| Antonucci, TK; Driscoll, JH; Faja, BW; Ghazzi, MN; Huang, SM; Perez, JE; Whitcomb, RW | 1 |
| Faulds, D; Plosker, GL | 1 |
| Awata, T; Chen, S; Katayama, S; Kosegawa, I; Negishi, K | 1 |
| Fukuzawa, M; Ikehata, F; Miyaguchi, S; Nakazawa, T; Ohta, S; Qiang, X; Sakata, Y; Satoh, J; Toyota, T | 1 |
| Horikoshi, H; Ikeda, Y; Mori, Y; Murakawa, Y; Okada, K; Tajima, N; Yokoyama, J | 1 |
| Dandona, P; Izzo, JL; Sung, BH; Wilson, MF | 1 |
| Gonoi, T; Inagaki, N; Ishida, H; Seino, S; Seino, Y; Sunaga, Y; Yamada, Y | 1 |
| Aaronson, PI; Mishra, SK | 1 |
| Fonseca, V; Foyt, HL; Shen, K; Whitcomb, R | 1 |
| Izumiya, Y; Usuda, R; Yokoyama, M; Yoshizawa, M | 1 |
| Akutsu, H; Funada, J; Otani, T; Sekiya, M; Suzuki, J; Watanabe, K | 1 |
| Ebihara, L; Koide, H; Nakamura, T; Sekizuka, K; Shimada, N; Suzuki, S; Ushiyama, C | 1 |
| Armstrong, D; Baxi, S; Caulfield, M; Chu, NV; Deutsch, R; Henry, RR; Kim, DD; Kong, AP; Mudaliar, SR; Reaven, PD; Reitz, R | 1 |
| Abe, T; Ishibashi, S; Ishikawa, S; Kawakami, A; Kusaka, I; Nagasaka, S; Nakamura, T; Saito, T | 1 |
| Aroda, V; Bandukwala, R; Baxi, S; Carter, L; Ciaraldi, TP; Henry, RR; Kong, AP; Mudaliar, SR; Phillips, SA | 1 |
| Herédi-Szabó, K; Ioja, E; Kis, E; Krajcsi, P; Nagy, T; Szente, L | 1 |
| Benoit-Biancamano, MO; Fortin, JS | 1 |
| Adams, LA; Bedwell, DW; Calvert, NA; Cassidy, KC; Cramer, JW; Mohutsky, MA; Moulton, RD; Rougée, LR; Ruterbories, KJ; Yumibe, NP; Zhou, X | 1 |
3 review(s) available for troglitazone and glyburide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug Induced Liver Injury (DILI). Mechanisms and Medicinal Chemistry Avoidance/Mitigation Strategies.
Topics: Animals; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Drug Discovery; Drug Evaluation, Preclinical; Hepatocytes; Humans; Liver; Mitochondria, Liver; Pharmaceutical Preparations; Risk Assessment; Tissue Distribution | 2020 |
Troglitazone: a review of its use in the management of type 2 diabetes mellitus.
Topics: Adult; Aged; Animals; Area Under Curve; Chromans; Diabetes Mellitus, Type 2; Drug Interactions; Glucose; Glyburide; Half-Life; Humans; Hypoglycemic Agents; Randomized Controlled Trials as Topic; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
8 trial(s) available for troglitazone and glyburide
| Article | Year |
|---|---|
Cardiac and glycemic benefits of troglitazone treatment in NIDDM. The Troglitazone Study Group.
Topics: Blood Glucose; C-Peptide; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Chromans; Confidence Intervals; Diabetes Mellitus, Type 2; Echocardiography; Female; Glyburide; Glycated Hemoglobin; Heart; Heart Function Tests; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Stroke Volume; Thiazoles; Thiazolidinediones; Time Factors; Triglycerides; Troglitazone | 1997 |
Effect of troglitazone on body fat distribution in type 2 diabetic patients.
Topics: Abdomen; Adipose Tissue; Blood Glucose; Blood Pressure; Body Mass Index; Chromans; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glucose Tolerance Test; Glyburide; Humans; Hypoglycemic Agents; Lipids; Male; Middle Aged; Skin; Thiazoles; Thiazolidinediones; Tomography, X-Ray Computed; Troglitazone; Viscera | 1999 |
Vasodilatory effects of troglitazone improve blood pressure at rest and during mental stress in type 2 diabetes mellitus.
Topics: Adult; Blood Pressure; Chromans; Diabetes Mellitus, Type 2; Female; Glyburide; Hemodynamics; Humans; Hypoglycemic Agents; Male; Middle Aged; Reference Values; Rest; Stress, Psychological; Thiazoles; Thiazolidinediones; Troglitazone; Vasodilation | 1999 |
Long-term effects of troglitazone: open-label extension studies in type 2 diabetic patients.
Topics: Blood Glucose; C-Peptide; Chromans; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Lipids; Lipoproteins, HDL; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Beneficial effect of troglitazone, an insulin-sensitizing antidiabetic agent, on coronary circulation in patients with non-insulin-dependent diabetes mellitus.
Topics: Adenosine Triphosphate; Aged; Blood Glucose; Case-Control Studies; Chromans; Coronary Circulation; Diabetes Mellitus, Type 2; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; Thallium Radioisotopes; Thiazoles; Thiazolidinediones; Troglitazone; Vasodilator Agents | 2001 |
Effect of troglitazone on urinary albumin excretion and serum type IV collagen concentrations in Type 2 diabetic patients with microalbuminuria or macroalbuminuria.
Topics: Albuminuria; Animals; Blood Pressure; Chromans; Collagen; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Middle Aged; Reference Values; Thiazoles; Thiazolidinediones; Troglitazone | 2001 |
Differential effects of metformin and troglitazone on cardiovascular risk factors in patients with type 2 diabetes.
Topics: Blood Glucose; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Chromans; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipids; Lipoproteins, LDL; Male; Metformin; Middle Aged; Plasminogen Activator Inhibitor 1; Risk Factors; Thiazoles; Thiazolidinediones; Troglitazone | 2002 |
Modulation of circulating and adipose tissue adiponectin levels by antidiabetic therapy.
Topics: Adipocytes; Adiponectin; Adipose Tissue; Adult; Aged; Biopsy; Chromans; Culture Media, Conditioned; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Male; Metformin; Middle Aged; Molecular Weight; Obesity; Proteins; Thiazoles; Thiazolidinediones; Tissue Distribution; Troglitazone | 2003 |
22 other study(ies) available for troglitazone and glyburide
| Article | Year |
|---|---|
Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile salt
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biliary Tract; Biological Transport, Active; Cholestasis, Intrahepatic; Chromans; Cytosol; Female; Glyburide; Hypoglycemic Agents; Liver; Male; Rats; Rats, Wistar; Sex Factors; Sulfates; Taurocholic Acid; Thiazoles; Thiazolidinediones; Troglitazone | 2001 |
Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport, Active; Biomarkers; Cells, Cultured; Drug Interactions; Fluorescent Dyes; Humans | 2003 |
Poorly soluble marketed drugs display solvation limited solubility.
Topics: Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Principal Component Analysis; Solubility; Tandem Mass Spectrometry; Thermodynamics | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Polypharmacology of N
Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adiponectin; Animals; Cell Line; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Insulin Resistance; Ligands; Male; Mice; Mice, Inbred C57BL; Polypharmacology; PPAR delta; PPAR gamma; Receptor, Adenosine A3 | 2017 |
2-Formyl-komarovicine promotes adiponectin production in human mesenchymal stem cells through PPARγ partial agonism.
Topics: Adipogenesis; Adiponectin; Binding Sites; Bone Marrow Cells; Cell Line; Chromans; Fluorescence Resonance Energy Transfer; Humans; Indoles; Ligands; Mesenchymal Stem Cells; Molecular Docking Simulation; PPAR gamma; Protein Binding; Protein Structure, Tertiary; Pyridines; Quinolines; Thiazolidinediones; Troglitazone | 2018 |
Effects of Troglitazone (CS-045) on insulin secretion in isolated rat pancreatic islets and HIT cells: an insulinotropic mechanism distinct from glibenclamide.
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Binding Sites; Cell Line; Cells, Cultured; Chromans; Cricetinae; Glucose; Glucose Transporter Type 2; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Monosaccharide Transport Proteins; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Receptors, Drug; Sulfonylurea Receptors; Thiazoles; Thiazolidinediones; Troglitazone | 1995 |
Troglitazone and metformin, but not glibenclamide, decrease blood pressure in Otsuka Long Evans Tokushima Fatty rats.
Topics: Animals; Blood Glucose; Blood Pressure; Catecholamines; Chromans; Diabetes Mellitus, Type 2; Glucose Transporter Type 4; Glyburide; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Male; Metformin; Monosaccharide Transport Proteins; Muscle Proteins; Rats; Rats, Inbred OLETF; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
Inhibition of tumor necrosis factor-alpha with anti-diabetic agents.
Topics: Animals; Biological Assay; Cells, Cultured; Chromans; Enzyme-Linked Immunosorbent Assay; Female; Gliclazide; Glyburide; Humans; Hypoglycemic Agents; Interleukin-1; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Thiazoles; Thiazolidinediones; Troglitazone; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Troglitazone but not pioglitazone affects ATP-sensitive K(+) channel activity.
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Chromans; COS Cells; Diazoxide; Electrophysiology; Glyburide; Membrane Potentials; Pinacidil; Pioglitazone; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Recombinant Fusion Proteins; Rubidium Radioisotopes; Sulfonylurea Receptors; Thiazoles; Thiazolidinediones; Transfection; Troglitazone | 1999 |
Differential block by troglitazone and rosiglitazone of glibenclamide-sensitive K(+) current in rat aorta myocytes.
Topics: Animals; Aorta, Thoracic; Chromans; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Potassium Channel Blockers; Rats; Rats, Wistar; Rosiglitazone; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
Acute rhabdomyolysis associated with troglitazone.
Topics: Chromans; Creatine Kinase; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Isoenzymes; Middle Aged; Rhabdomyolysis; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Pioglitazone-induced hepatic injury in a patient previously receiving troglitazone with success.
Topics: Chromans; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Liver; Middle Aged; Pioglitazone; Thiazoles; Thiazolidinediones; Troglitazone | 2002 |
Effect of membrane cholesterol on BSEP/Bsep activity: species specificity studies for substrates and inhibitors.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biological Transport, Active; Blotting, Western; Cell Line; Cell Membrane; Cholesterol; Chromans; Cyclosporine; Electrophoresis, Polyacrylamide Gel; Glyburide; Humans; Hypoglycemic Agents; Immunosuppressive Agents; Insecta; Kinetics; Mice; Rats; Species Specificity; Substrate Specificity; Thiazolidinediones; Troglitazone; Vesicular Transport Proteins | 2009 |
In vitro evaluation of hypoglycemic agents to target human islet amyloid polypeptide: a key protein involved in amyloid deposition and beta-cell loss.
Topics: Amyloid; Amyloidosis; Animals; Carbamates; Cell Survival; Chromans; Circular Dichroism; Glyburide; Humans; Hypoglycemic Agents; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Piperidines; Protein Structure, Secondary; Rats; Thiazolidinediones; Troglitazone | 2015 |
Difference in the Pharmacokinetics and Hepatic Metabolism of Antidiabetic Drugs in Zucker Diabetic Fatty and Sprague-Dawley Rats.
Topics: Administration, Intravenous; Animals; Biotransformation; Canagliflozin; Chromans; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Glyburide; Hepatocytes; Humans; Hypoglycemic Agents; Liver; Male; Metformin; Rats, Sprague-Dawley; Rats, Zucker; Rosiglitazone; Species Specificity; Substrate Specificity; Sulfotransferases; Thiazolidinediones; Troglitazone | 2016 |