troglitazone has been researched along with dactinomycin in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Tafuri, SR | 1 |
| Fleck, E; Goetze, S; Gotlibowski, T; Hsueh, WA; Kawano, H; Law, RE; Xi, XP | 1 |
| Leff, T; Su, TZ; Wang, M; Wise, SC | 1 |
| Goto, K; Mu, YM; Nawata, H; Nishi, Y; Takayanagi, R; Yanase, T | 1 |
| Brunmair, B; Fürnsinn, C; Gras, F; Neschen, S; Roden, M; Wagner, L; Waldhäusl, W | 1 |
| Baek, SJ; Eling, TE; Hsi, LC; Wilson, LC | 1 |
| Cheon, H; Choi, SJ; Ji, JD; Kim, HJ; Lee, YH; Rho, YH; Sohn, J; Song, GG; Um, JW | 1 |
| Bertin, I; Dauça, M; Domenjoud, L; Fiatte, C; Huin, C; Lesuffleur, T; Plénat, F; Pluvinet, A; Schohn, H; Touche, N | 1 |
1 review(s) available for troglitazone and dactinomycin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
12 other study(ies) available for troglitazone and dactinomycin
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Troglitazone enhances differentiation, basal glucose uptake, and Glut1 protein levels in 3T3-L1 adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Adipocytes; Animals; Biological Transport; Cell Differentiation; Chromans; Dactinomycin; Deoxyglucose; Glucose; Glucose Transporter Type 1; Humans; Hypoglycemic Agents; Insulin; Mice; Monosaccharide Transport Proteins; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Transcription, Genetic; Troglitazone | 1996 |
PPAR gamma-ligands inhibit migration mediated by multiple chemoattractants in vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Cells, Cultured; Chemotactic Factors; Chromans; Cycloheximide; Dactinomycin; Enzyme Activation; Insulin-Like Growth Factor I; Ligands; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Prostaglandin D2; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Thrombin; Transcription Factors; Troglitazone | 1999 |
Troglitazone, an antidiabetic agent, inhibits cholesterol biosynthesis through a mechanism independent of peroxisome proliferator-activated receptor-gamma.
Topics: 3T3 Cells; Animals; Anticholesteremic Agents; Cell Line; CHO Cells; Cholesterol; Chromans; Cricetinae; Cycloheximide; Dactinomycin; Hypoglycemic Agents; Mice; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Receptors, Cytoplasmic and Nuclear; RNA; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 1999 |
Combined treatment with specific ligands for PPARgamma:RXR nuclear receptor system markedly inhibits the expression of cytochrome P450arom in human granulosa cancer cells.
Topics: Aromatase; Cell Division; Chromans; Dactinomycin; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Induction; Estrone; Female; Granulosa Cell Tumor; Humans; Ligands; Nicotinic Acids; Ovary; Promoter Regions, Genetic; Radioimmunoassay; Receptors, Cytoplasmic and Nuclear; Receptors, FSH; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone; Tumor Cells, Cultured | 2001 |
Direct thiazolidinedione action on isolated rat skeletal muscle fuel handling is independent of peroxisome proliferator-activated receptor-gamma-mediated changes in gene expression.
Topics: Animals; Chromans; Cycloheximide; Dactinomycin; Drug Interactions; Energy Metabolism; Gene Expression; In Vitro Techniques; Insulin Resistance; Ligands; Male; Muscle, Skeletal; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone | 2001 |
Troglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma ) ligand, selectively induces the early growth response-1 gene independently of PPAR gamma. A novel mechanism for its anti-tumorigenic activity.
Topics: 3' Untranslated Regions; Antineoplastic Agents; Apoptosis; Base Sequence; Cell Division; Chromans; Colorectal Neoplasms; Dactinomycin; DNA Primers; DNA-Binding Proteins; Early Growth Response Protein 1; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immediate-Early Proteins; K562 Cells; Plasmids; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Transfection; Troglitazone; Tumor Cells, Cultured; Zinc Fingers | 2003 |
15-Deoxy-delta12,14-PGJ2 inhibits IL-6-induced Stat3 phosphorylation in lymphocytes.
Topics: Arthritis, Rheumatoid; Chromans; Cycloheximide; Dactinomycin; DNA-Binding Proteins; Gene Expression Regulation; Humans; Hypoglycemic Agents; Interleukin-6; Jurkat Cells; Lymphocytes; NF-kappa B; Phosphorylation; PPAR gamma; Prostaglandin D2; Protein Synthesis Inhibitors; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Thiazolidinediones; Trans-Activators; Troglitazone | 2005 |
Genetic analysis of peroxisome proliferator-activated receptor gamma1 splice variants in human colorectal cell lines.
Topics: Base Sequence; Caco-2 Cells; Chromans; Chromosome Mapping; Colonic Neoplasms; Cycloheximide; Dactinomycin; Exons; HCT116 Cells; HT29 Cells; Humans; Pioglitazone; PPAR gamma; Protein Isoforms; RNA, Messenger; Thiazolidinediones; Troglitazone; Untranslated Regions | 2006 |