troglitazone has been researched along with d-alpha tocopherol in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.70) | 18.7374 |
| 1990's | 11 (40.74) | 18.2507 |
| 2000's | 11 (40.74) | 29.6817 |
| 2010's | 4 (14.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aizawa, Y; Fujita, T; Hasegawa, K; Horikoshi, H; Kanai, T; Kurumada, T; Yoshioka, T | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Morita, M; Naito, Y; Niki, E; Yoshikawa, T | 1 |
| Kaku, K; Kaneko, T; Nagasaka, Y; Nakamura, K | 1 |
| Horikoshi, H; Kato, Y; Kodama, T; Niki, E; Noguchi, N; Sakai, H; Tsuchiya, J; Yamamoto, Y | 1 |
| Campagnola, M; Cominacini, L; Davoli, A; Fratta Pasini, A; Garbin, U; Lo Cascio, V; Pastorino, AM; Rigoni, A | 1 |
| Inoue, I; Katayama, S; Komoda, T; Miyazaki, T; Negishi, K; Sonoda, M; Takahashi, K | 1 |
| Campagnola, M; Cominacini, L; Davoli, A; Ferrannini, E; Foot, E; Fratta Pasini, A; Garbin, U; Lo Cascio, V; Sighieri, G; Sironi, AM | 1 |
| Ishizawa, M; Ishizuka, T; Itaya, S; Kajita, K; Kanoh, Y; Kimura, M; Miura, A; Muto, N; Wada, H; Yasuda, K | 1 |
| Fujimura, S; Nakamura, K; Ono, J; Suzumiya, J | 1 |
| Fujiwara, T; Horikoshi, H; Ikeda, K; Matsuda, K; Ohsawa, T; Okuno, A; Takahashi, S; Ushiyama, S | 1 |
| McCarty, MF | 1 |
| Bashan, N; Khamaisi, M; Potashnik, R; Rudich, A; Tirosh, A | 1 |
| Campagnola, M; Cominacini, L; Davoli, A; Garbin, U; Lo Cascio, V; Pasini, AF; Rigoni, A; Tosetti, L | 1 |
| Kobayashi, K; Nagai, Y; Nohara, E; Ohta, MY; Takamura, T | 1 |
| Menzel, J; Sobal, G | 1 |
| Hisatome, I; Ogino, K; Shigemasa, C; Shimoyama, M; Uchida, K | 1 |
| Hishinuma, T; Mizugaki, M; Yamazaki, T | 1 |
| May, JM; Qu, ZC | 1 |
| Arima, S; Ikeda, Y; Ito, S; Kudo, M; Sato, K; Sugawara, A; Takeuchi, K; Taniyama, Y; Uruno, A | 1 |
| Chvojková, S; Divisová, J; Kazdová, L | 1 |
| Davies, GF; Khandelwal, RL; McFie, PJ; Roesler, WJ | 1 |
| Ahmad, H; Brown, RD; Fox, J; Gen, M; Greyson, C; Long, CS; Lu, L; Perlov, D; Schwartz, GG; Weiss, SO; Xu, Y; Zhu, P | 1 |
| Adachi, N; Fukunaga-Takenaka, R; Merida, I; Merino, E; Saito, N; Sakai, N; Shirai, Y; Yagi, K | 1 |
| O'Brien, PJ; Tafazoli, S; Wright, JS | 1 |
| Arnold, LL; Cohen, SM; Kakiuchi-Kiyota, S; Koza-Taylor, P; Pennington, KL; Suzuki, S; Varney, M; Yokohira, M | 1 |
1 review(s) available for troglitazone and d-alpha tocopherol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for troglitazone and d-alpha tocopherol
| Article | Year |
|---|---|
Troglitazone reduces LDL oxidation and lowers plasma E-selectin concentration in NIDDM patients.
Topics: Analysis of Variance; Arteriosclerosis; Cholesterol, LDL; Chromans; Diabetes Mellitus, Type 2; Double-Blind Method; E-Selectin; Endothelium, Vascular; Female; Fluorescence; Humans; Hypoglycemic Agents; Male; Middle Aged; Oxidation-Reduction; Peroxides; Thiazoles; Thiazolidinediones; Thiobarbituric Acid Reactive Substances; Troglitazone; Vitamin E | 1998 |
25 other study(ies) available for troglitazone and d-alpha tocopherol
| Article | Year |
|---|---|
Studies on hindered phenols and analogues. 1. Hypolipidemic and hypoglycemic agents with ability to inhibit lipid peroxidation.
Topics: Animals; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Peroxidation; Male; Mice; Mice, Inbred BALB C; Phenols; Rats; Structure-Activity Relationship | 1989 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Inhibition of plasma lipid oxidation induced by peroxyl radicals, peroxynitrite, hypochlorite, 15-lipoxygenase, and singlet oxygen by clinical drugs.
Topics: Animals; Antioxidants; Antipyrine; Arachidonate 15-Lipoxygenase; Edaravone; Free Radicals; Hypochlorous Acid; Lipid Metabolism; Lipids; Mice; Oxidants; Oxidation-Reduction; Peroxides; Peroxynitrous Acid; Plasma; Probucol; Singlet Oxygen | 2016 |
The new oral hypoglycemic agent, CS-045, inhibits the lipid peroxidation of human plasma low density lipoprotein in vitro.
Topics: Administration, Oral; Amidines; Chromans; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Lipid Peroxidation; Lipoproteins, LDL; Thiazoles; Thiazolidinediones; Thiobarbituric Acid Reactive Substances; Time Factors; Troglitazone; Vitamin E | 1995 |
Inhibition of oxidation of low density lipoprotein by troglitazone.
Topics: Antioxidants; Ascorbic Acid; Benzhydryl Compounds; Chromans; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hypoglycemic Agents; Lipid Peroxidation; Lipoproteins, LDL; Oxidation-Reduction; Thiazoles; Thiazolidinediones; Thiobarbituric Acid Reactive Substances; Troglitazone; Vitamin E | 1996 |
Effects of troglitazone on in vitro oxidation of LDL and HDL induced by copper ions and endothelial cells.
Topics: Arteriosclerosis; Cells, Cultured; Chromans; Copper; Diabetes Mellitus; Endothelium; Humans; Hypoglycemic Agents; Lipoproteins, HDL; Lipoproteins, LDL; Oxidation-Reduction; Thiazoles; Thiazolidinediones; Troglitazone; Vitamin E | 1997 |
Troglitazone has a scavenging effect on reactive oxygen species.
Topics: Antioxidants; Chromans; Cytochrome c Group; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Humans; Hydrogen Peroxide; Iron; Molecular Structure; Neutrophils; Pioglitazone; Reactive Oxygen Species; Spin Labels; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Troglitazone; Vitamin E; Xanthine; Xanthine Oxidase; Xanthines | 1997 |
Differential effect of the antidiabetic thiazolidinediones troglitazone and pioglitazone on human platelet aggregation mechanism.
Topics: Adenosine Diphosphate; Blood Platelets; Blood Proteins; Chromans; Collagen; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Hypoglycemic Agents; In Vitro Techniques; Isoenzymes; Kinetics; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphorylation; Pioglitazone; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Thiazoles; Thiazolidinediones; Thrombin; Troglitazone; Vitamin E | 1998 |
Effects of troglitazone on the growth and differentiation of hematopoietic cell lines.
Topics: Animals; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Division; Cell Line; Chromans; G1 Phase; Hematopoietic Stem Cells; HL-60 Cells; Humans; Hypoglycemic Agents; Mice; Monocytes; Phosphorylation; Retinoblastoma Protein; Thiazoles; Thiazolidinediones; Troglitazone; Vitamin E | 1998 |
Troglitazone, a new antidiabetic agent possessing radical scavenging ability, improved decreased skin blood flow in diabetic rats.
Topics: Animals; Aorta, Thoracic; Blood Glucose; Chromans; Diabetes Mellitus, Experimental; Dinoprostone; Epoprostenol; Fibroblasts; Free Radical Scavengers; Guinea Pigs; Hindlimb; Hypoglycemic Agents; In Vitro Techniques; Lipoxygenase Inhibitors; Male; Rats; Rats, Sprague-Dawley; Rats, Wistar; Regional Blood Flow; Skin; Thiazoles; Thiazolidinediones; Troglitazone; Vasodilation; Vitamin E | 1998 |
Complementary measures for promoting insulin sensitivity in skeletal muscle.
Topics: Adipocytes; Animals; Chromans; Chromium; Fatty Acids, Nonesterified; Fish Oils; Humans; Hypoglycemic Agents; Insulin Resistance; Islets of Langerhans; Liver; Muscle, Skeletal; Protein Kinase C; Receptor, Insulin; Thiazoles; Thiazolidinediones; Troglitazone; Vanadium; Vitamin E | 1998 |
Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Ascorbic Acid; Biological Transport; Chromans; Glucose; Glucose Oxidase; Glucose Transporter Type 4; Glutathione; Hydrogen Peroxide; Hypoglycemic Agents; Insulin; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Oxidative Stress; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Thiazoles; Thiazolidinediones; Thioctic Acid; Troglitazone; Vitamin E | 1999 |
The expression of adhesion molecules on endothelial cells is inhibited by troglitazone through its antioxidant activity.
Topics: Antioxidants; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; E-Selectin; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; NF-kappa B; Signal Transduction; Thiazoles; Thiazolidinediones; Troglitazone; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1; Vitamin E | 1999 |
Inhibitory effect of troglitazone on tumor necrosis factor alpha-induced expression of monocyte chemoattractant protein-1 in human mesangial cells.
Topics: Blotting, Northern; Cell Count; Cell Survival; Cells, Cultured; Chemokine CCL2; Chromans; Enzyme-Linked Immunosorbent Assay; Glomerular Mesangium; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hypoglycemic Agents; RNA, Messenger; Thiazoles; Thiazolidinediones; Troglitazone; Tumor Necrosis Factor-alpha; Vitamin E | 2000 |
The role of antioxidants in the long-term glycation of low density lipoprotein and its Cu2+-catalyzed oxidation.
Topics: Antioxidants; Aspirin; Chromans; Copper; Edetic Acid; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Humans; Lipoproteins, LDL; Oxidation-Reduction; Spectrometry, Fluorescence; Thiazoles; Thiazolidinediones; Troglitazone; Vitamin E | 2000 |
Acute hemodynamic effects of insulin-sensitizing agents in isolated perfused rat hearts.
Topics: Animals; Chromans; Dose-Response Relationship, Drug; Hemodynamics; Hypoglycemic Agents; Indomethacin; Isoxazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Pioglitazone; Prostaglandins; Rats; Rats, Wistar; Rosiglitazone; Thiazoles; Thiazolidinediones; Troglitazone; Vitamin E | 2000 |
Troglitazone has a reducing effect on thromboxane production.
Topics: Arachidonic Acid; Blood Platelets; Chromans; Diabetes Mellitus, Type 2; Fibrinolytic Agents; Gas Chromatography-Mass Spectrometry; Humans; Leukemia, Erythroblastic, Acute; Rosiglitazone; Thiazoles; Thiazolidinediones; Thromboxane A2; Troglitazone; Tumor Cells, Cultured; Vitamin E | 2000 |
Troglitazone protects human erythrocytes from oxidant damage.
Topics: Antioxidants; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Erythrocyte Membrane; Erythrocytes; Free Radicals; Humans; Lipid Peroxides; Liposomes; Oxidative Stress; Thiazoles; Thiazolidinediones; Time Factors; Troglitazone; Vitamin E | 2000 |
Differential effects among thiazolidinediones on the transcription of thromboxane receptor and angiotensin II type 1 receptor genes.
Topics: alpha-Tocopherol; Animals; Cells, Cultured; Chromans; Gene Expression; Hypoglycemic Agents; Muscle, Smooth, Vascular; Pioglitazone; Promoter Regions, Genetic; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cytoplasmic and Nuclear; Receptors, Thromboxane; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone | 2001 |
A comparison of the effects of troglitazone and vitamin E on the fatty acid composition of serum phospholipids in an experimental model of insulin resistance.
Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Chromans; Disease Models, Animal; Fatty Acids; Female; Hyperinsulinism; Hypertriglyceridemia; Hypoglycemic Agents; Insulin Resistance; Rats; Rats, Mutant Strains; Rats, Wistar; Thiazoles; Thiazolidinediones; Troglitazone; Vitamin E | 2001 |
Unique ability of troglitazone to up-regulate peroxisome proliferator-activated receptor-gamma expression in hepatocytes.
Topics: Animals; Blotting, Northern; Blotting, Western; Chromans; Hepatocytes; Humans; Hypoglycemic Agents; Ligands; Male; Mice; Mice, Inbred C57BL; Plasmids; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Troglitazone; Up-Regulation; Vitamin E | 2002 |
PPAR-gamma activation fails to provide myocardial protection in ischemia and reperfusion in pigs.
Topics: alpha-Tocopherol; Animals; Antioxidants; Chromans; Coronary Circulation; Cytokines; Energy Metabolism; Fatty Acids, Nonesterified; Female; Hypoglycemic Agents; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; PPAR gamma; RNA, Messenger; Rosiglitazone; Sus scrofa; Thiazolidinediones; Troglitazone; Ventricular Function, Left | 2005 |
Importance of chroman ring and tyrosine phosphorylation in the subtype-specific translocation and activation of diacylglycerol kinase alpha by D-alpha-tocopherol.
Topics: alpha-Tocopherol; Animals; Cells, Cultured; Chromans; Cricetinae; Diacylglycerol Kinase; Enzyme Activation; Green Fluorescent Proteins; Humans; Isoenzymes; Mutation; Phosphorylation; Protein Kinase Inhibitors; Protein Transport; Recombinant Fusion Proteins; Thiazolidinediones; Tocopherols; Troglitazone; Tyrosine; Vitamin E | 2005 |
Prooxidant and antioxidant activity of vitamin E analogues and troglitazone.
Topics: Animals; Antioxidants; Cell Survival; Cell-Free System; Chromans; Glutathione; Hepatocytes; Hydrogen Peroxide; Lipid Peroxidation; Male; Microsomes, Liver; Oxidants; Oxidation-Reduction; Peroxidase; Phenols; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Thiazolidinediones; Tocopherols; Troglitazone; Vitamin E | 2005 |
Evaluation of direct and indirect effects of the PPARγ agonist troglitazone on mouse endothelial cell proliferation.
Topics: Adipose Tissue; Animals; Antineoplastic Agents; Body Weight; Cell Growth Processes; Cell Hypoxia; Cell Line; Chromans; Drinking; Endothelial Cells; Fatty Liver; Female; Gene Expression Regulation; Gene Regulatory Networks; Hemangiosarcoma; Hepatocytes; Histocytochemistry; Insulin-Like Growth Factor I; Liver; Mice; Organ Size; Oxidative Stress; PPAR gamma; Reproducibility of Results; Thiazolidinediones; Troglitazone; Vitamin E | 2011 |