Page last updated: 2024-08-16

troglitazone and ascorbic acid

troglitazone has been researched along with ascorbic acid in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (22.22)	18.2507
2000's	2 (22.22)	29.6817
2010's	5 (55.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Atanasov, AG; Bauer, J; Bauer, R; Baumgartner, L; Bodensieck, A; Dirsch, VM; Fakhrudin, N; Favero, GD; Heiss, EH; Ladurner, A; Loggia, RD; Ponti, C; Rollinger, JM; Schwaiger, S; Sosa, S; Stuppner, H; Tubaro, A; Werz, O; Widowitz, U	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Horikoshi, H; Kato, Y; Kodama, T; Niki, E; Noguchi, N; Sakai, H; Tsuchiya, J; Yamamoto, Y	1
Bashan, N; Khamaisi, M; Potashnik, R; Rudich, A; Tirosh, A	1
Aso, Y; Inukai, T; Takanashi, K; Takemura, Y; Tayama, K	1
He, K; Talaat, RE; Woolf, TF	1

Reviews

1 review(s) available for troglitazone and ascorbic acid

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for troglitazone and ascorbic acid

Article	Year
High glucose concentrations abolish the superoxide dismutase response of leukocytes to ascorbic acid or troglitazone in type 2 diabetes mellitus. Life sciences, 2002, Apr-05, Volume: 70, Issue:20 Topics: Aged; Albuminuria; Antioxidants; Ascorbic Acid; Chromans; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Female; Glucose; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Leukocytes; Male; Middle Aged; Superoxide Dismutase; Thiazoles; Thiazolidinediones; Troglitazone	2002

Article

Year

High glucose concentrations abolish the superoxide dismutase response of leukocytes to ascorbic acid or troglitazone in type 2 diabetes mellitus.

Life sciences, 2002, Apr-05, Volume: 70, Issue:20

Topics: Aged; Albuminuria; Antioxidants; Ascorbic Acid; Chromans; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Female; Glucose; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Leukocytes; Male; Middle Aged; Superoxide Dismutase; Thiazoles; Thiazolidinediones; Troglitazone

2002

Other Studies

7 other study(ies) available for troglitazone and ascorbic acid

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and pro-inflammatory mediators in vitro. Journal of natural products, 2011, Aug-26, Volume: 74, Issue:8 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Austria; Benzofurans; Cyclooxygenase 1; Edema; Intramolecular Oxidoreductases; Krameriaceae; Lignans; Male; Mice; NF-kappa B; Plant Roots; Prostaglandin-E Synthases	2011
Inhibition of oxidation of low density lipoprotein by troglitazone. Atherosclerosis, 1996, Volume: 123, Issue:1-2 Topics: Antioxidants; Ascorbic Acid; Benzhydryl Compounds; Chromans; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hypoglycemic Agents; Lipid Peroxidation; Lipoproteins, LDL; Oxidation-Reduction; Thiazoles; Thiazolidinediones; Thiobarbituric Acid Reactive Substances; Troglitazone; Vitamin E	1996
Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes. Diabetologia, 1999, Volume: 42, Issue:8 Topics: 3T3 Cells; Adipocytes; Animals; Ascorbic Acid; Biological Transport; Chromans; Glucose; Glucose Oxidase; Glucose Transporter Type 4; Glutathione; Hydrogen Peroxide; Hypoglycemic Agents; Insulin; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Oxidative Stress; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Thiazoles; Thiazolidinediones; Thioctic Acid; Troglitazone; Vitamin E	1999
Incorporation of an oxygen from water into troglitazone quinone by cytochrome P450 and myeloperoxidase. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:4 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Ascorbic Acid; Benzene Derivatives; Carbon Radioisotopes; Catalase; Chromans; Chromatography, Liquid; Cysteine; Dexamethasone; Horseradish Peroxidase; Humans; Iodobenzenes; Male; Microsomes, Liver; Molecular Structure; Oxygen; Oxygen Isotopes; Peroxidase; Quinones; Rats; Rats, Inbred F344; Spectrometry, Mass, Electrospray Ionization; Superoxide Dismutase; Thiazolidinediones; Troglitazone; Water	2004