Page last updated: 2024-08-16

troglitazone and 2,4-thiazolidinedione

troglitazone has been researched along with 2,4-thiazolidinedione in 48 studies

Research

Studies (48)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (10.42)	18.2507
2000's	37 (77.08)	29.6817
2010's	4 (8.33)	24.3611
2020's	2 (4.17)	2.80

Authors

Authors	Studies
Akatsuka, H; Arakawa, K; Homma, K; Iijima, I; Inamasu, M; Kawanami, S; Matsumoto, M; Okumura, K; Ozeki, M; Saiga, Y; Watanabe, A; Yasuda, K	1
Cooksey, RC; Garvey, WT; Hebert, LF; McClain, DA; Wofford, P; Zhu, JH	1
Fleck, E; Goetze, S; Gotlibowski, T; Hsueh, WA; Kawano, H; Law, RE; Xi, XP	1
Hirase, N; Mu, Y; Muta, K; Nawata, H; Takayanagi, R; Umemura, T; Yanase, T	1
Kuzuya, T	1
Haneda, M; Isshiki, K; Kikkawa, R; Koya, D; Maeda, S; Sugimoto, T	1
Breyer, MD; Breyer, RM; Davis, L; Guan, YF; Zhang, YH	1
Daida, H; Sunayama, S; Watanabe, Y; Yamaguchi, H	1
Barbehenn, E; Lurie, P; Sasich, LD; Wolfe, SM	1
Adzet, T; Alegret, M; Cabrero, A; Laguna, JC; Sánchez, RM; Vázquez, M	1
Arioglu, E; Chao, L; Gavrilova, O; Marcus-Samuels, B; Mason, MM; Moitra, J; Reitman, ML; Vinson, C	1
Hirosumi, J; Kojo, H; Mutoh, S; Notsu, Y; Suzuki, A; Yasuno, T	1
Albrektsen, T; Fleckner, J	1
Dean, RG; Hausman, DB; Hausman, GJ; Tchoukalova, YD	1
Banerji, MA; Lebovitz, HE	1
Janka, HU	1
Hayashi, T; Hosoda, K; Inoue, G; Inoue, R; Masuzaki, H; Nakao, K; Nishimura, H; Ogawa, Y; Shintani, M; Yamamoto, Y; Yonemitsu, S	1
Abe, I; Eto, K; Fujishima, M; Nakamura, Y; Ohya, Y	1
Csermely, P; Jermendy, G	1
Palazzolo, MR; Solomon, SS; Usdan, LS	1
Jazet, IM; Meinders, AE	1
Inoue, K; Kawahito, Y; Kohno, M; Sano, H; Tsubouchi, Y; Yoshikawa, T; Yoshimura, R	1
Iwata, M; Kobayashi, M	1
Kitamura, R; Tanaka, Y	1
Scheen, AJ	1
Hiraoka, S; Kitamura, S; Kiyohara, T; Matsuzawa, Y; Miyazaki, Y; Nagasawa, Y; Shinomura, Y; Takakura, R; Toyota, M	1
Nelson, SD	1
Fujiwara, T; Hayashi, N; Horikoshi, H; Kobayashi, M; Shimizu, K; Shiratori, K	1
Montague, CT	1
Dixon, C; Doseff, AI; Hilbelink, T; Kotur, M; Lu, L; Rovin, BH; Wilmer, WA	1
Tolman, KG	1
Abourjaily, HM; Alsheikh-Ali, AA; Karas, RH	1
Brant, BP; Garvey, WT; Kennedy, A; Rogers, NL; Wallace, P; Willi, SM	1
Campbell, N; Chen, JH; Cory, DG; Dorfman, D; Enloe, BM; Fletcher, CD; Singer, S; Weybright, P	1
Plutzky, J; Raji, A	1
Hosaka, D; Imai, Y; Kawazu, S; Ohmura, E	1
Sakura, H	1
Chen, ZJ; Yang, LY; Yang, YN	1
Barrett, PH; Chait, A; Little, PJ; Tannock, LR; Tsoi, C; Wight, TN	1
Ahmad, H; Brown, RD; Fox, J; Gen, M; Greyson, C; Long, CS; Lu, L; Perlov, D; Schwartz, GG; Weiss, SO; Xu, Y; Zhu, P	1
Chen, CS; Gardner, OS; Graves, LM; Shiau, CW	1
Brandt, U; Brüne, B; Dröse, S; Soller, M; von Knethen, A	1
Chan, EC; Chui, WK; Ho, HK; New, LS; Saha, S	1
Furumura, M; Hashimoto, T; Karashima, T; Numata, S; Ohyama, B; Tanida, N; Teye, K; Yan, Y	1
Ding, RG; Fan, X; Hu, D; Li, ZJ; Liu, Y; Wang, QJ; Wu, CQ	1
Delgado, TC; Gaspar, JM; Jones, JG; Macedo, MP; Martins, FO; O'Doherty, RM; Scott, DK; Viegas, J	1
Bales, ES; Doyle, AS; Houck, JA; Julian, CG; Lane, SL; Lorca, RA; Moore, LG	1
Gopal, K; Haque, M; Kashfi, K; Pérez, DJ; Tabatabaei Dakhili, SA; Ussher, JR; Velázquez-Martínez, CA	1

Reviews

14 review(s) available for troglitazone and 2,4-thiazolidinedione

Article	Year
[The development of thiazolidinedione drugs as anti-diabetic agents]. Nihon rinsho. Japanese journal of clinical medicine, 2000, Volume: 58, Issue:2 Topics: Animals; Chemical and Drug Induced Liver Injury; Chromans; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin Resistance; Mice; Rosiglitazone; Thiazoles; Thiazolidinediones; Troglitazone	2000
Thiazolidinediones, dyslipidaemia and insulin resistance syndrome. Current opinion in lipidology, 2000, Volume: 11, Issue:4 Topics: Chromans; Clinical Trials as Topic; Glucose; Humans; Hyperlipidemias; Hypoglycemic Agents; Insulin Resistance; Phenotype; Thiazoles; Thiazolidinediones; Troglitazone	2000
Insulin resistance and its treatment by thiazolidinediones. Recent progress in hormone research, 2001, Volume: 56 Topics: Adipose Tissue; Binding Sites; Chromans; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dimerization; Drug Interactions; Endothelium, Vascular; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Islets of Langerhans; Male; Models, Biological; Muscle, Smooth; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Sex Factors; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone	2001
[Glitazones. Profile of a new class of substances]. Der Internist, 2001, Volume: 42, Issue:4 Topics: Albuminuria; Animals; Anticholesteremic Agents; Chromans; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Germany; Humans; Hypoglycemic Agents; Isoenzymes; Pioglitazone; Rosiglitazone; Thiazoles; Thiazolidinediones; Troglitazone; United States	2001
[Thiazolidinediones--a new class of oral antidiabetic drugs]. Orvosi hetilap, 2001, Jul-22, Volume: 142, Issue:29 Topics: Animals; Chromans; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metabolic Syndrome; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone	2001
[The thiazolidinedione derivates: a new class of oral blood glucose lowering agents]. Nederlands tijdschrift voor geneeskunde, 2001, Aug-11, Volume: 145, Issue:32 Topics: Administration, Oral; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone	2001
[Evaluation of thiazolidinedione derivative drugs for safety]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:11 Topics: Animals; Chemical and Drug Induced Liver Injury; Chromans; Clinical Trials as Topic; Edema; Heart Failure; Humans; Hypoglycemic Agents; Pioglitazone; Thiazoles; Thiazolidinediones; Troglitazone	2001
[Clinical usefulness of combination treatment with thiazolidinedione and insulin]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:11 Topics: Chromans; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Insulin; Multicenter Studies as Topic; Pioglitazone; Thiazoles; Thiazolidinediones; Troglitazone	2001
Hepatotoxicity with thiazolidinediones: is it a class effect? Drug safety, 2001, Volume: 24, Issue:12 Topics: Aged; Chemical and Drug Induced Liver Injury; Chromans; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Pioglitazone; Rosiglitazone; Structure-Activity Relationship; Thiazoles; Thiazolidinediones; Troglitazone	2001
Structure toxicity relationships--how useful are they in predicting toxicities of new drugs? Advances in experimental medicine and biology, 2001, Volume: 500 Topics: Analgesics; Androgen Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Benzophenones; Bromobenzenes; Chromans; Drug-Related Side Effects and Adverse Reactions; Flutamide; Humans; Hypoglycemic Agents; Indoles; Molecular Structure; Oxindoles; Pharmaceutical Preparations; Quinolones; Structure-Activity Relationship; Thiazoles; Thiazolidinediones; Thiophenes; Troglitazone	2001
Thiazolidinedione hepatotoxicity: a class effect? International journal of clinical practice. Supplement, 2000, Issue:113 Topics: Chemical and Drug Induced Liver Injury; Chromans; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Thiazoles; Thiazolidinediones; Troglitazone	2000
Insulin resistance, diabetes, and atherosclerosis: thiazolidinediones as therapeutic interventions. Current cardiology reports, 2002, Volume: 4, Issue:6 Topics: Adipose Tissue; Animals; Chromans; Coronary Artery Disease; Diabetes Mellitus; Diabetic Angiopathies; Humans; Hypoglycemic Agents; Insulin Resistance; Lipoproteins; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone	2002
[Combination therapy of insulin sensitizer, thiazolidinedione drugs, and sulfonylurea]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 9 Topics: Blood Glucose; Chromans; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Pioglitazone; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones; Troglitazone	2002
[Combination therapy with biguanides]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 10 Topics: Acarbose; Biguanides; Chromans; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Metformin; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones; Treatment Outcome; Troglitazone	2002

Other Studies

34 other study(ies) available for troglitazone and 2,4-thiazolidinedione

Article	Year
Novel benzoxazole 2,4-thiazolidinediones as potent hypoglycemic agents. Synthesis and structure-activity relationships. Chemical & pharmaceutical bulletin, 1997, Volume: 45, Issue:12 Topics: Animals; Benzopyrans; Benzoxazoles; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Male; Mice; Obesity; Pioglitazone; Rosiglitazone; Structure-Activity Relationship; Thiazoles; Thiazolidinediones; Troglitazone	1997
Mechanism of hexosamine-induced insulin resistance in transgenic mice overexpressing glutamine:fructose-6-phosphate amidotransferase: decreased glucose transporter GLUT4 translocation and reversal by treatment with thiazolidinedione. Endocrinology, 1999, Volume: 140, Issue:3 Topics: Animals; Chromans; Gene Expression Regulation, Enzymologic; Glucose; Glucose Clamp Technique; Glucose Transporter Type 4; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Hexosamines; Hypoglycemic Agents; Insulin Resistance; Liver; Mice; Mice, Transgenic; Monosaccharide Transport Proteins; Muscle Proteins; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone	1999
PPAR gamma-ligands inhibit migration mediated by multiple chemoattractants in vascular smooth muscle cells. Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:5 Topics: Animals; Aorta, Thoracic; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Cells, Cultured; Chemotactic Factors; Chromans; Cycloheximide; Dactinomycin; Enzyme Activation; Insulin-Like Growth Factor I; Ligands; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Prostaglandin D2; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Thrombin; Transcription Factors; Troglitazone	1999
Thiazolidinedione induces apoptosis and monocytic differentiation in the promyelocytic leukemia cell line HL60. Oncology, 1999, Volume: 57 Suppl 2 Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Differentiation; Chromans; Drug Synergism; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Monocytes; Nicotinic Acids; Proto-Oncogene Proteins; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Troglitazone	1999
Thiazolidinedione compounds ameliorate glomerular dysfunction independent of their insulin-sensitizing action in diabetic rats. Diabetes, 2000, Volume: 49, Issue:6 Topics: Albuminuria; Animals; Chromans; Diabetes Mellitus, Experimental; Diglycerides; Extracellular Matrix Proteins; Hemodynamics; Insulin; Kidney Glomerulus; Male; Mitogen-Activated Protein Kinases; Pioglitazone; Protein Kinase C; Rats; Rats, Sprague-Dawley; Renal Circulation; RNA, Messenger; Thiazoles; Thiazolidinediones; Transforming Growth Factor beta; Troglitazone	2000
Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in human transitional bladder cancer and its role in inducing cell death. Neoplasia (New York, N.Y.), 1999, Volume: 1, Issue:4 Topics: Alitretinoin; Antineoplastic Agents; Apoptosis; Carcinoma, Transitional Cell; Carrier Proteins; Cell Death; Chromans; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; G1 Phase; Humans; Immunoblotting; In Situ Hybridization; Ligands; Luciferases; Myelin P2 Protein; Neoplasm Proteins; Nicotinic Acids; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Ribonucleases; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Transfection; Tretinoin; Troglitazone; Tumor Cells, Cultured; Tumor Suppressor Proteins; Urinary Bladder Neoplasms	1999
Information on thiazolidinediones. Lancet (London, England), 2000, Jul-15, Volume: 356, Issue:9225 Topics: Chromans; Drug Industry; Humans; Hypoglycemic Agents; Internet; Ligands; Pioglitazone; Rosiglitazone; Thiazoles; Thiazolidinediones; Troglitazone; United States; United States Food and Drug Administration	2000
Down-regulation of uncoupling protein-3 and -2 by thiazolidinediones in C2C12 myotubes. FEBS letters, 2000, Oct-27, Volume: 484, Issue:1 Topics: Acyl-CoA Dehydrogenase; Animals; Atorvastatin; Bezafibrate; Carnitine O-Palmitoyltransferase; Carrier Proteins; Cell Line; Cholesterol; Chromans; Down-Regulation; Fatty Acid Desaturases; Heptanoic Acids; Hypoglycemic Agents; Ion Channels; Ligands; Membrane Transport Proteins; Mice; Mitochondrial Proteins; Muscles; Oleic Acid; Peroxisome Proliferators; Proteins; Pyrimidines; Pyrroles; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Triazenes; Troglitazone; Uncoupling Protein 2; Uncoupling Protein 3	2000
Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones. The Journal of clinical investigation, 2000, Volume: 106, Issue:10 Topics: Adipose Tissue; Animals; Blood Glucose; Chromans; Diabetes Mellitus, Lipoatrophic; Disease Models, Animal; Female; Hypoglycemic Agents; Insulin; Ligands; Liver; Mice; Mice, Inbred C57BL; Mice, Transgenic; Receptors, Cytoplasmic and Nuclear; Respiratory Function Tests; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Triglycerides; Troglitazone	2000
Alteration in expression profiles of a series of diabetes-related genes in db/db mice following treatment with thiazolidinediones. Japanese journal of pharmacology, 2000, Volume: 84, Issue:2 Topics: Adipocytes; Animals; Blood Glucose; Body Weight; Chromans; Diabetes Mellitus, Experimental; Female; Gene Expression; Gene Expression Profiling; Hypoglycemic Agents; Liver; Mice; Muscles; Pioglitazone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone	2000
The transcription factor Fos-related antigen 1 is induced by thiazolidinediones during differentiation of 3T3-L1 cells. Molecular pharmacology, 2001, Volume: 59, Issue:3 Topics: 3T3 Cells; Animals; Cell Differentiation; Cell Nucleus; Chromans; Dimerization; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypoglycemic Agents; Mice; Pioglitazone; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Cytoplasmic and Nuclear; RNA Stability; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Troglitazone; Up-Regulation	2001
Enhancing effect of troglitazone on porcine adipocyte differentiation in primary culture: a comparison with dexamethasone. Obesity research, 2000, Volume: 8, Issue:9 Topics: Adipocytes; Adipose Tissue; Animals; Blotting, Western; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Cells, Cultured; Chromans; Dexamethasone; Drug Synergism; Enhancer Elements, Genetic; Glucocorticoids; Immunochemistry; Morphogenesis; Receptors, Cytoplasmic and Nuclear; Sugar Alcohol Dehydrogenases; Swine; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone	2000
Troglitazone induces GLUT4 translocation in L6 myotubes. Diabetes, 2001, Volume: 50, Issue:5 Topics: Animals; Biological Transport; Cell Line; Cell Membrane; Chromans; Cycloheximide; Deoxyglucose; Gene Expression Regulation; Glucose Transporter Type 1; Glucose Transporter Type 3; Glucose Transporter Type 4; Insulin; Kinetics; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Nerve Tissue Proteins; Protein Transport; Rats; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone	2001
Comparative actions of insulin sensitizers on ion channels in vascular smooth muscle. European journal of pharmacology, 2001, Jun-29, Volume: 423, Issue:1 Topics: Analysis of Variance; Animals; Barium; Calcium; Chromans; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; Humans; Insulin Resistance; Ion Channels; Isoxazoles; Membrane Potentials; Muscle, Smooth, Vascular; Pioglitazone; Potassium Channels; Prostaglandin D2; Rosiglitazone; Thiazoles; Thiazolidinediones; Troglitazone	2001
Mechanisms involved in tumor necrosis factor-alpha induction of insulin resistance and its reversal by thiazolidinedione(s). The American journal of the medical sciences, 2001, Volume: 322, Issue:2 Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Chromans; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Insulin Resistance; Ligands; Liver Neoplasms; Rats; Thiazoles; Thiazolidinediones; Troglitazone; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	2001
Expression of peroxisome proliferator-activated receptor gamma in renal cell carcinoma and growth inhibition by its agonists. Biochemical and biophysical research communications, 2001, Sep-28, Volume: 287, Issue:3 Topics: Antineoplastic Agents; Blotting, Western; Carcinoma, Renal Cell; Cell Division; Chromans; Coloring Agents; Dose-Response Relationship, Drug; Humans; Hypoglycemic Agents; Immunohistochemistry; Immunologic Factors; Kidney Neoplasms; Ligands; Pioglitazone; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Cells, Cultured; Up-Regulation	2001
PPARgamma agonists inhibit cell growth and suppress the expression of cyclin D1 and EGF-like growth factors in ras-transformed rat intestinal epithelial cells. International journal of cancer, 2001, Nov-01, Volume: 94, Issue:3 Topics: Animals; Blotting, Northern; Blotting, Western; Cell Division; Cell Line; Cell Line, Transformed; Cell Nucleus; Chromans; Cyclin D1; DNA, Complementary; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial Cells; Flow Cytometry; Humans; Hypoglycemic Agents; Intestines; Ligands; Luciferases; Plasmids; Promoter Regions, Genetic; ras Proteins; Rats; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Troglitazone	2001
Thiazolidinedione derivatives as novel therapeutic agents to prevent the development of chronic pancreatitis. Pancreas, 2002, Volume: 24, Issue:2 Topics: Amylases; Animals; Antineoplastic Agents; Blood Glucose; Chromans; Chronic Disease; Disease Models, Animal; DNA; Gene Expression; Hypoglycemic Agents; Insulin; Interleukin-8; Macrophages, Peritoneal; Male; Organ Size; Pancreatitis; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Necrosis Factor-alpha	2002
A treatment for Mr WP: thiazolidinediones after troglitazone. Diabetic medicine : a journal of the British Diabetic Association, 2002, Volume: 19 Suppl 1 Topics: Aged; Animals; Body Mass Index; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Mice, Knockout; Obesity; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone	2002
15-Deoxy-Delta12,14-prostaglandin J2 regulates mesangial cell proliferation and death. Kidney international, 2002, Volume: 61, Issue:4 Topics: 1-Phosphatidylinositol 4-Kinase; Cell Death; Cell Division; Cells, Cultured; Chromans; Chromones; Enzyme Inhibitors; Glomerular Mesangium; Humans; Morpholines; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone	2002
Risk of adverse events with concomitant use of atorvastatin or simvastatin and glucose-lowering drugs (thiazolidinediones, metformin, sulfonylurea, insulin, and acarbose). The American journal of cardiology, 2002, Jun-01, Volume: 89, Issue:11 Topics: Acarbose; Adverse Drug Reaction Reporting Systems; Anticholesteremic Agents; Atorvastatin; Chromans; Drug Interactions; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Pyrroles; Simvastatin; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones; Troglitazone	2002
Effective use of thiazolidinediones for the treatment of glucocorticoid-induced diabetes. Diabetes research and clinical practice, 2002, Volume: 58, Issue:2 Topics: Administration, Oral; Adult; Biomarkers; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Fructosamine; Glucocorticoids; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Leptin; Middle Aged; Prednisone; Thiazoles; Thiazolidinediones; Troglitazone	2002
Biochemical correlates of thiazolidinedione-induced adipocyte differentiation by high-resolution magic angle spinning NMR spectroscopy. Magnetic resonance in medicine, 2002, Volume: 48, Issue:4 Topics: 3T3 Cells; Adipocytes; Animals; Antineoplastic Agents; Cell Differentiation; Cells, Cultured; Chromans; Flow Cytometry; Humans; Ligands; Liposarcoma; Magnetic Resonance Spectroscopy; Mice; Phosphatidylcholines; Phosphorylcholine; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone	2002
[The effect of peroxisome proliferator-activated receptor alpha and gamma ligands on free fatty acid-induced INS-1 cell impairment]. Zhonghua nei ke za zhi, 2003, Volume: 42, Issue:12 Topics: Animals; Anticholesteremic Agents; Apoptosis; Cell Line, Tumor; Chromans; Clofibrate; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulinoma; Receptors, Cytoplasmic and Nuclear; Thiazolidinediones; Transcription Factors; Troglitazone	2003
Thiazolidinediones reduce the LDL binding affinity of non-human primate vascular cell proteoglycans. Diabetologia, 2004, Volume: 47, Issue:5 Topics: Animals; Binding Sites; Cells, Cultured; Chromans; Hypoglycemic Agents; Lipoproteins, LDL; Macaca nemestrina; Muscle, Smooth, Vascular; Proteoglycans; Thiazolidinediones; Troglitazone	2004
PPAR-gamma activation fails to provide myocardial protection in ischemia and reperfusion in pigs. American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:3 Topics: alpha-Tocopherol; Animals; Antioxidants; Chromans; Coronary Circulation; Cytokines; Energy Metabolism; Fatty Acids, Nonesterified; Female; Hypoglycemic Agents; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; PPAR gamma; RNA, Messenger; Rosiglitazone; Sus scrofa; Thiazolidinediones; Troglitazone; Ventricular Function, Left	2005
Peroxisome proliferator-activated receptor gamma-independent activation of p38 MAPK by thiazolidinediones involves calcium/calmodulin-dependent protein kinase II and protein kinase R: correlation with endoplasmic reticulum stress. The Journal of biological chemistry, 2005, Mar-18, Volume: 280, Issue:11 Topics: Animals; Antineoplastic Agents; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromans; Culture Media, Serum-Free; eIF-2 Kinase; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Enzyme Activation; Epithelial Cells; Immunoblotting; Immunoprecipitation; Ligands; Liver; MAP Kinase Kinase 3; MAP Kinase Kinase 6; Models, Biological; Models, Chemical; p38 Mitogen-Activated Protein Kinases; Phosphorylation; PPAR gamma; Protein Binding; Rats; Signal Transduction; Sulfonamides; Thiazolidinediones; Time Factors; Troglitazone	2005
Mechanism of thiazolidinedione-dependent cell death in Jurkat T cells. Molecular pharmacology, 2007, Volume: 71, Issue:6 Topics: Adenosine Triphosphate; Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Chromans; Humans; Jurkat Cells; Mitochondria; Necrosis; PPAR gamma; Reactive Oxygen Species; Rosiglitazone; T-Lymphocytes; Thiazolidinediones; Troglitazone	2007
Investigation of the role of the thiazolidinedione ring of troglitazone in inducing hepatotoxicity. Toxicology letters, 2010, Feb-01, Volume: 192, Issue:2 Topics: Cell Line; Cell Survival; Chromans; Drug Stability; Glutathione; Hepatocytes; Humans; Hypoglycemic Agents; Liver; Liver Failure; PPAR gamma; Protein Carbonylation; Thiazolidinediones; Troglitazone	2010
Various peroxisome proliferator-activated receptor (PPAR)-γ agonists differently induce differentiation of cultured human keratinocytes. Experimental dermatology, 2015, Volume: 24, Issue:1 Topics: Anti-Inflammatory Agents; Benzimidazoles; Benzoates; Cell Differentiation; Cells, Cultured; Chromans; Filaggrin Proteins; Gene Expression Regulation; Humans; Intermediate Filament Proteins; Keratinocytes; Membrane Proteins; Microscopy, Fluorescence; Pioglitazone; PPAR gamma; RNA, Messenger; Rosiglitazone; Skin; Telmisartan; Thiazolidinediones; Troglitazone	2015
Characterizing the mechanism of thiazolidinedione-induced hepatotoxicity: An in vitro model in mitochondria. Toxicology and applied pharmacology, 2015, Apr-15, Volume: 284, Issue:2 Topics: Cell Line, Tumor; Chromans; DNA, Mitochondrial; Electron Transport; Humans; Hypoglycemic Agents; Liver; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Pioglitazone; Reactive Oxygen Species; Rosiglitazone; Thiazolidinediones; Troglitazone	2015
Mechanisms by which the thiazolidinedione troglitazone protects against sucrose-induced hepatic fat accumulation and hyperinsulinaemia. British journal of pharmacology, 2016, Volume: 173, Issue:2 Topics: Animals; Chromans; Fatty Liver; Hyperinsulinism; Hypoglycemic Agents; Male; Protective Agents; Rats; Rats, Wistar; Sucrose; Thiazolidinediones; Troglitazone	2016
Peroxisome proliferator-activated receptor gamma blunts endothelin-1-mediated contraction of the uterine artery in a murine model of high-altitude pregnancy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:3 Topics: Animals; Disease Models, Animal; Endothelin-1; Female; Fetal Growth Retardation; Hypoxia; Immunohistochemistry; Mice; Phenylephrine; Placenta; PPAR gamma; Pregnancy; Thiazolidinediones; Troglitazone; Uterine Artery	2020
SP1-independent inhibition of FOXM1 by modified thiazolidinediones. European journal of medicinal chemistry, 2021, Jan-01, Volume: 209 Topics: Amino Acid Sequence; Antineoplastic Agents; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Forkhead Box Protein M1; Gene Expression Regulation, Neoplastic; Humans; Models, Molecular; Protein Binding; Sp1 Transcription Factor; Thiazolidinediones; Triple Negative Breast Neoplasms; Troglitazone	2021