trispheridine has been researched along with hemanthamine* in 2 studies
2 other study(ies) available for trispheridine and hemanthamine
| Article | Year |
|---|---|
[Study on the chemical constituents from the bulbs of Zephyranthes candida].
To study the chemical constituents from the bulbs of Zephyranthes candida.. The chemical constituents were separated and purified by means of several chromatographies and their structures were elucidated by spectroscopic methods.. Six compounds were isolated and identified as trisphaeridine (I), p-hydroxybenzaldehyde (II), sucrose (III), (-)-amarbellisine (IV), lycorine (V), (+)-haemanthamine (VI).. Compounds I - IV are obtained from this genus for the first time. Topics: Amaryllidaceae Alkaloids; Benzaldehydes; Dioxoles; Ethanol; Liliaceae; Magnetic Resonance Spectroscopy; Phenanthridines; Plant Roots; Sucrose | 2010 |
Antiproliferative amaryllidaceae alkaloids isolated from the bulbs of Sprekelia formosissima and Hymenocallis x festalis.
Seven alkaloids were isolated from Sprekelia formosissima, and five from Hymenocallis x festalis. Tazettine, lycorine, haemanthidine and haemanthamine were evaluated for antiproliferative and multidrug resistance (mdr) reversing activity on mouse lymphoma cells. Lycorine, haemanthidine and haemanthamine displayed pronounced cell growth inhibitory activities against both drug-sensitive and drug-resistant cell lines, but did not significantly inhibit mdr-1 p-glycoprotein. Thus, the tested alkaloids are apparently not substrates for the mdr efflux pump. Assays for interactions with DNA and RNA revealed that the antiproliferative effects of lycorine and haemanthamine result from their complex formation with RNA. Topics: Alkaloids; Amaryllidaceae Alkaloids; Aniline Compounds; Animals; Antineoplastic Agents, Phytogenic; Dioxoles; DNA; Drug Resistance, Multiple; Leukemia L5178; Magnoliopsida; Mice; Molecular Structure; Nucleic Acid Denaturation; Phenanthridines; Plant Stems; RNA, Transfer; Tumor Cells, Cultured; Verapamil | 2002 |