Page last updated: 2024-08-24

triptonide and triptolide

triptonide has been researched along with triptolide in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (36.84)29.6817
2010's8 (42.11)24.3611
2020's4 (21.05)2.80

Authors

AuthorsStudies
Aiyama, R; Aoyagi, Y; Fukaya, H; Hashimoto, S; Hasuda, T; Hitotsuyanagi, Y; Matsuzaki, T; Takeya, K2
Aiyama, R; Aoyagi, Y; Fukaya, H; Hashimoto, S; Hasuda, T; Hitotsuyanagi, Y; Matsuyama, S; Matsuzaki, T; Takeya, K1
Deng, G; Ding, J; Feng, H; Li, Y; Miao, Z; Yang, Y; Zhou, B1
Chen, Y; Feng, H; Li, Y; Tang, H; Xu, H1
Cen, S; He, Y; Hu, L; Li, Q; Li, X; Liu, Y; Wu, M; Zhou, J1
Chen, X; Hou, S; Mo, L; Ning, C; Tu, W; Wu, J; Xu, J1
Kinghorn, AD; Ren, Y1
Xu, M; Yang, D; Ye, XY1
Lin, N; Liu, QL; Qian, SZ; Xu, Y; Zhang, JW1
Bi, KS; Guo, DA; Guo, HZ; Han, J; Ning, LL; Zhang, XY1
Guo, D; Wang, Z; Wen, J; Xing, J1
Chan, JK; Chan, KL; Fan, ST; Luk, JM; Tam, P; Wong, KF; Yang, D1
Chen, R; Li, C; Li, H; Li, Y; Tang, Y; Xue, J; Zhang, H1
Feng, H; Li, Y; Tang, H; Xu, H1
Chen, Z; He, L; Liang, Z; Peng, L; Zhao, F1
Chen, X; Li, M; Liu, C; Luo, Q; Qiu, F; Sun, X; Tao, Y1
Dai, L; He, GN; Song, J1
Chen, B; He, QL; Huang, Q; Lin, GQ; Meng, H; Tan, C; Wang, Z; Zhang, W; Zheng, C1

Reviews

1 review(s) available for triptonide and triptolide

ArticleYear
A comprehensive review on celastrol, triptolide and triptonide: Insights on their pharmacological activity, toxicity, combination therapy, new dosage form and novel drug delivery routes.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 162

    Topics: Diterpenes; Epoxy Compounds; Humans; Neoplasms; Phenanthrenes; Triterpenes

2023

Other Studies

18 other study(ies) available for triptonide and triptolide

ArticleYear
Semisynthesis of C-ring modified triptolide analogues and their cytotoxic activities.
    Bioorganic & medicinal chemistry letters, 2006, Apr-01, Volume: 16, Issue:7

    Topics: Cell Line, Tumor; Diterpenes; Drug Screening Assays, Antitumor; Epoxy Compounds; Humans; Models, Molecular; Phenanthrenes; Structure-Activity Relationship

2006
Fluorination of triptolide and its analogues and their cytotoxicity.
    Bioorganic & medicinal chemistry letters, 2008, Apr-01, Volume: 18, Issue:7

    Topics: Antineoplastic Agents; Cell Line, Tumor; Diethylamines; Diterpenes; Epoxy Compounds; Fluorides; Fluorine; HT29 Cells; Humans; Hydrocarbons, Fluorinated; Models, Chemical; Phenanthrenes; Stereoisomerism; Structure-Activity Relationship; Sulfur Compounds

2008
Synthesis and biological evaluation of novel triptolide analogues for anticancer activity.
    Bioorganic & medicinal chemistry letters, 2010, Nov-01, Volume: 20, Issue:21

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Crystallography, X-Ray; Diterpenes; Drug Screening Assays, Antitumor; Epoxy Compounds; Humans; Indicators and Reagents; Models, Molecular; Phenanthrenes; Structure-Activity Relationship; Tripterygium

2010
Semisynthesis of triptolide analogues: effect of γ-lactone and C-14 substituents on cytotoxic activities.
    Bioorganic & medicinal chemistry letters, 2011, May-15, Volume: 21, Issue:10

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Diterpenes; Epoxy Compounds; Humans; Lactones; Molecular Structure; Phenanthrenes

2011
Semisynthesis of triptolide analogues: effect of B-ring substituents on cytotoxic activities.
    Bioorganic & medicinal chemistry letters, 2014, Dec-15, Volume: 24, Issue:24

    Topics: Antineoplastic Agents; Cell Proliferation; Diterpenes; Drug Screening Assays, Antitumor; Epoxy Compounds; Glioma; Humans; Male; Models, Molecular; Molecular Structure; Organic Chemicals; Phenanthrenes; Prostatic Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured

2014
Identification of Triptophenolide from
    ACS medicinal chemistry letters, 2016, Dec-08, Volume: 7, Issue:12

    Topics:

2016
Triptolide derivatives as potential multifunctional anti-Alzheimer agents: Synthesis and structure-activity relationship studies.
    Bioorganic & medicinal chemistry letters, 2018, 02-15, Volume: 28, Issue:4

    Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Transformed; Diterpenes; Epoxy Compounds; Memantine; Mice; Neurons; Neuroprotective Agents; Peptide Fragments; Phenanthrenes; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2018
Development of Potential Antitumor Agents from the Scaffolds of Plant-Derived Terpenoid Lactones.
    Journal of medicinal chemistry, 2020, 12-24, Volume: 63, Issue:24

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Products; Diterpenes; Humans; Neoplasms; Sesquiterpenes; Structure-Activity Relationship; Triterpenes

2020
Enantioselective total synthesis of (-)-triptolide, (-)-triptonide, (+)-triptophenolide, and (+)-triptoquinonide.
    The Journal of organic chemistry, 2000, Apr-07, Volume: 65, Issue:7

    Topics: Crystallography, X-Ray; Cyclization; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Phenanthrenes; Stereoisomerism; Triterpenes

2000
[Effects of chlorotriptolide and triptonide on chromosome aberration and micronuclei of bone marrow cell in male rats].
    Zhonghua nan ke xue = National journal of andrology, 2002, Volume: 8, Issue:6

    Topics: Animals; Bone Marrow Cells; Chromosome Aberrations; Diterpenes; Epoxy Compounds; Infertility, Male; Male; Micronuclei, Chromosome-Defective; Phenanthrenes; Rats; Rats, Sprague-Dawley; Tripterygium; Triterpenes

2002
Biotransformation of triptolide and triptonide by cell suspension cultures of Catharanthus roseus.
    Journal of Asian natural products research, 2004, Volume: 6, Issue:2

    Topics: Biotransformation; Catharanthus; Cells, Cultured; Diterpenes; Epoxy Compounds; Phenanthrenes; Triterpenes

2004
Determination of triptolide and triptonide in human plasma by high-performance liquid chromatography.
    Biomedical chromatography : BMC, 2005, Volume: 19, Issue:1

    Topics: Adult; Chromatography, High Pressure Liquid; Diterpenes; Epoxy Compounds; Female; Humans; Phenanthrenes; Plant Extracts; Reproducibility of Results; Triterpenes

2005
Immunochemical characterization of the functional constituents of Tripterygium wilfordii contributing to its anti-inflammatory property.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cell Proliferation; Cell Survival; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Epoxy Compounds; Humans; Immunosuppressive Agents; Inhibitory Concentration 50; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Molecular Structure; Phenanthrenes; Plant Extracts; Rats; Rats, Inbred Lew; Structure-Activity Relationship; Tripterygium; Triterpenes

2008
New facile enantio- and diastereo-selective syntheses of (-)-triptonide and (-)-triptolide.
    Organic & biomolecular chemistry, 2014, Feb-07, Volume: 12, Issue:5

    Topics: Catalysis; Chemistry Techniques, Synthetic; Diterpenes; Epoxy Compounds; Models, Molecular; Molecular Conformation; Phenanthrenes; Stereoisomerism; Substrate Specificity; Triterpenes

2014
Divergent total synthesis of triptolide, triptonide, tripdiolide, 16-hydroxytriptolide, and their analogues.
    The Journal of organic chemistry, 2014, Nov-07, Volume: 79, Issue:21

    Topics: Catalysis; Diterpenes; Epoxy Compounds; Indium; Lactones; Palladium; Phenanthrenes; Triterpenes

2014
Modulation of IL-37 expression by triptolide and triptonide in THP-1 cells.
    Cellular & molecular immunology, 2015, Volume: 12, Issue:4

    Topics: Anti-Inflammatory Agents; Cell Line, Tumor; Diterpenes; Epoxy Compounds; Gene Expression Regulation; Humans; Interleukin-1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phenanthrenes; Tripterygium; Triterpenes

2015
Screening of major hepatotoxic components of Tripterygium wilfordii based on hepatotoxic injury patterns.
    BMC complementary medicine and therapies, 2023, Jan-10, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Mice; RNA, Messenger; Tripterygium; Tumor Necrosis Factor-alpha; Zebrafish

2023
DCTPP1, a reliable Q-biomarker for comprehensive evaluation of the quality of tripterygium glycoside tablets based on chemical references.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 119

    Topics: Biomarkers; Cardiac Glycosides; Drugs, Chinese Herbal; Glycosides; Molecular Docking Simulation; Tablets; Tandem Mass Spectrometry; Tripterygium

2023