triphenylethylene has been researched along with stilbenes in 64 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 25 (39.06) | 18.7374 |
1990's | 15 (23.44) | 18.2507 |
2000's | 9 (14.06) | 29.6817 |
2010's | 12 (18.75) | 24.3611 |
2020's | 3 (4.69) | 2.80 |
Authors | Studies |
---|---|
De Mieri, M; Hamburger, M; Hering, S; Jähne, EA; Raith, M; Rueda, DC; Schöffmann, A | 1 |
Desombre, ER; Gatley, SJ; Hughes, A; Li, J; Mease, RC; Pan, ML; Seevers, RE | 1 |
Arnstein, HR; Cannon, M; Halliwell, B; Smith, C; Wiseman, H | 1 |
Bignon, E; Crastes de Paulet, A; Doré, JC; Gilbert, J; Miquel, JF; Ojasoo, T; Pons, M; Raynaud, JP | 2 |
Leclercq, G; Legros, N; McCague, R | 1 |
Metzler, M; Schiffmann, D | 1 |
Bignon, E; Crastes de Paulet, A; Gilbert, J; Ojasoo, T; Pons, M; Raynaud, JP | 1 |
Bignon, E; Gilbert, J; Nishizuka, Y; Pons, M | 1 |
Dey, SK; Huet-Hudson, YM | 1 |
Clark, JH; Guthrie, S | 1 |
Barrera, G; Dianzani, MU; Farina, A; Ferretti, C; Frati, L; Gulino, A; Paradisi, L; Parola, M; Screpanti, I; Vacca, A | 1 |
Barrera, G; Dianzani, MU; Farina, A; Ferretti, C; Frati, L; Gulino, A; Screpanti, I; Vacca, A | 1 |
Bignon, E; Crastes de Paulet, A; Gilbert, J; Pons, M | 1 |
Anderson, BW; O'Brian, CA; Ward, NE | 1 |
Liskamp, RM; O'Brian, CA; Solomon, DH; Weinstein, IB | 1 |
Clark, JH; Guthrie, SC; Mitchell, WC | 1 |
Farina, A; Frati, L; Gulino, A; Modesti, A; Screpanti, I; Vacca, A | 1 |
Papendorp, JT; Sonnenschein, C; Soto, AM | 1 |
Clark, JH; Guthrie, SC; Winneker, RC | 1 |
Grinenko, GS; Kappusheva, LM; Kareva, EN; Savel'eva, GM; Sergeev, PV; Solov'eva, EV | 1 |
Blankenstein, MA; Thijssen, JH; van den Koedijk, CD | 1 |
Blankenstein, MA; Govers, RM; Thijssen, JH; van den Koedijk, CD | 1 |
Chiappetta, C; Hyder, SM; Stancel, GM | 1 |
Bérubé, G; Gicquaud, C; Grenier, G | 1 |
Bérubé, G; Gaudreault, RC; Séné, A | 1 |
De Los Reyes, A; England, G; Jordan, VC; Lee, ES; O'Regan, RM; Schafer, JM; Yao, K | 1 |
Clegg, NJ; Scanlan, TS; Weatherman, RV | 1 |
Bahamonde, MI; Diaz, M; Hardy, SP; Lock, H; Muñoz, FJ; Posas, F; Valverde, MA | 1 |
Díaz, M | 1 |
Barrell, KJ; Kirby, A; LE Lain, R; Nicholls, PJ; Saeed, GS; Simons, C; Smith, HJ | 1 |
Chu, FM; Guan, MZ; Guo, ZR; Liang, XT; Wang, NG; Xu, BL | 1 |
APELGOT, S; CHEUTIN, A; HURST, L; MARS, S | 1 |
BUU-HOI, NP; DELOR, J; GLEY, P; NAM, NH; XUONG, ND | 1 |
BUU-HOI, NP; CORRE-HURST, L; XUONG, ND | 1 |
APELGOT, S; MORIN, GA | 1 |
STUCKI, JC; THOMPSON, CR | 1 |
BORIS, A; FOX, HH | 1 |
NISHIZUKA, Y | 1 |
DAVIES, JS; ROBSON, JM; TEBRICH, W | 1 |
APELGOT, S; BUU-HOI, NP; COSTEROUSSE, O; DAUDEL, P; LACASSAGNE, A | 1 |
Awasthi, S; Blesson, CS; Daverey, A; Dwivedi, A; Kharkwal, G | 1 |
Liu, ZL; Wei, Q; Yang, L; Zheng, L; Zhou, B | 1 |
Blackmore, PF; Chatterjie, N; Dobrydneva, Y; Fichandler, CE; Fitzgerald, MC; Morrell, MM; Trebley, JP; Weatherman, RV | 1 |
TARDOS, W | 1 |
FARAHAT, K; ROBSON, JM; TARDOS, W | 1 |
CARTER, PR; HEY, DH | 1 |
ROBSON, JM; TADROS, W | 1 |
BERGER, M; BUN-HOI, NP | 1 |
EMMENS, CW | 1 |
Chi, ZG; Li, HY; Li, XF; Liu, SW; Xu, BJ; Xu, JR; Zhang, XQ; Zhang, Y; Zhou, W | 1 |
Mombelli, E | 1 |
Chen, H; Gu, Y; Li, S; Li, X; Wang, K; Yao, Y; Zhao, J; Zhou, L | 1 |
Chen, H; Li, S; Li, X; Lv, M; Yao, Y; Zhao, L | 1 |
Curpan, R; Jordan, VC; Obiorah, I; Sengupta, S | 1 |
Chen, H; Gu, Y; Li, S; Li, X; Lv, M; Tan, G; Wang, K; Yao, Y | 1 |
Barth, BM; Cabot, MC; Claxton, DF; Feith, DJ; Fox, TE; Kester, M; Loughran, TP; Morad, SA; Tan, SF | 1 |
Cushman, M; Flockhart, DA; Ipe, J; Jin, HS; Liu, J; Lv, W; Skaar, TC; Zhao, LM | 1 |
Abderrahman, B; Curpan, RF; Fan, P; Fanning, SW; Greene, GL; Greenland, JA; Jordan, VC; Maximov, PY; Rajan, SS; Rincon, DMQ; Sengupta, S | 1 |
Krysan, DJ; Montoya, MC | 1 |
Chen, H; Cui, N; Lin, DD; Shen, Y; Shi, JG; Shi, JH; Wang, B; Zhao, MZ; Zheng, L | 1 |
Abderrahman, B; Broom, BM; Chen, Y; Curpan, RF; Fan, P; Fanning, SW; Foulds, CE; Greene, GL; Greenland, JA; Han, R; Hawsawi, YM; Jain, A; Jordan, VC; Malovannaya, A; Maximov, PY; Quintana Rincon, DM | 1 |
Luxami, V; Paul, K; Rani, S | 1 |
Abadi, AH; Ahmed, NS; Hassan, AS; Vollmer, G; Wober, J | 1 |
2 review(s) available for triphenylethylene and stilbenes
Article | Year |
---|---|
Speculation on the mechanism of action of triphenylethylene antioestrogens.
Topics: Animals; Binding Sites; Breast Neoplasms; Estradiol; Estrogen Antagonists; Estrogen Replacement Therapy; Humans; Receptors, Estrogen; Stilbenes; Tamoxifen | 1994 |
Repurposing Estrogen Receptor Antagonists for the Treatment of Infectious Disease.
Topics: Animals; Bacteria; Communicable Diseases; Drug Repositioning; Estrogen Receptor Antagonists; Female; Humans; Mice; Parasites; Stilbenes; Tamoxifen; Toremifene; Viruses | 2018 |
62 other study(ies) available for triphenylethylene and stilbenes
Article | Year |
---|---|
Identification of dihydrostilbenes in Pholidota chinensis as a new scaffold for GABAA receptor modulators.
Topics: Animals; Oocytes; Orchidaceae; Patch-Clamp Techniques; Plant Extracts; Plant Roots; Plant Stems; Protein Subunits; Receptors, GABA-A; Stilbenes; Xenopus laevis | 2014 |
Synthesis, purification and stability of no carrier added radioiodinated 1,1-bis(4-hydroxyphenyl)-2-iodo-2-phenylethylene (IBHPE), a prototype triphenylethylene estrogen-receptor binding radiopharmaceutical.
Topics: Aging; Animals; Chromatography, High Pressure Liquid; Drug Stability; Estrogen Antagonists; Female; Rats; Receptors, Estrogen; Stilbenes; Tissue Distribution; Ultracentrifugation; Uterus | 1991 |
The antioxidant action of ketoconazole and related azoles: comparison with tamoxifen and cholesterol.
Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Cattle; Cholesterol; Ergosterol; Estrogen Antagonists; Ferric Compounds; Iron; Ketoconazole; Lipid Peroxidation; Liposomes; Male; Microsomes, Liver; Phospholipids; Rats; Stilbenes; Tamoxifen | 1991 |
Influence of di- and tri-phenylethylene estrogen/antiestrogen structure on the mechanisms of protein kinase C inhibition and activation as revealed by a multivariate analysis.
Topics: Animals; Binding Sites; Enzyme Activation; Estrogen Antagonists; Models, Molecular; Multivariate Analysis; Protein Kinase C; Rats; Stilbenes; Structure-Activity Relationship; Styrenes | 1991 |
Effect of estrogenic and antiestrogenic triphenylethylene derivatives on progesterone and estrogen receptors levels of MCF-7 cells.
Topics: Animals; Binding, Competitive; Cytosol; Estrogen Antagonists; Estrogens; Phosphorylation; Receptors, Estrogen; Receptors, Progesterone; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured | 1991 |
Structural requirements for the in vitro transformation of Syrian hamster embryo cells by stilbene estrogens and triphenylethylene-type antiestrogens.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Estrogen Antagonists; Estrogens, Non-Steroidal; Fibrosarcoma; Mesocricetus; Mice; Mice, Nude; Stilbenes; Structure-Activity Relationship | 1991 |
Hydroxylated triphenylacrylonitriles adopt a unique orientation within the binding site of the estrogen receptor.
Topics: Animals; Binding Sites; Cattle; Estrogen Antagonists; Female; Hydroxylation; Models, Molecular; Molecular Conformation; Molecular Structure; Receptors, Estrogen; Stilbenes; Structure-Activity Relationship; Uterus | 1990 |
Multiple mechanisms of protein kinase C inhibition by triphenylacrylonitrile antiestrogens.
Topics: Acrylonitrile; Animals; Binding Sites; Diglycerides; Enzyme Activation; Estrogen Antagonists; Phosphatidylserines; Protein Kinase C; Rats; Stilbenes | 1990 |
Differential effects of ovarian steroids and triphenylethylene compounds on macromolecular uptake and thymidine incorporation in the mouse uterus.
Topics: Animals; Capillary Permeability; Clomiphene; DNA; Estradiol; Estriol; Estrogens; Female; Mice; Nitromifene; Progesterone; Serum Albumin, Bovine; Stilbenes; Uterus | 1990 |
Subcellular localization of triphenylethylene antiestrogen binding sites (TABS) in rat liver.
Topics: Animals; Cell Fractionation; Cell Nucleus; Charcoal; Dextrans; Estrogen Antagonists; Female; Liver; Microsomes, Liver; Mitochondria, Liver; Potassium Chloride; Rats; Rats, Inbred Strains; Stilbenes; Tamoxifen | 1986 |
Structure-activity relationships of calmodulin antagonism by triphenylethylene antiestrogens.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Calmodulin; Estradiol; Estrogen Antagonists; Nafoxidine; Stilbenes; Structure-Activity Relationship; Tamoxifen | 1986 |
Calmodulin antagonism and growth-inhibiting activity of triphenylethylene antiestrogens in MCF-7 human breast cancer cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Breast Neoplasms; Calmodulin; Cell Division; Cell Line; Cyclic Nucleotide Phosphodiesterases, Type 1; Estrogen Antagonists; Female; Humans; Protein Kinase C; Stilbenes; Tamoxifen; Tetradecanoylphorbol Acetate | 1986 |
Analogies and differences in the modulation of progesterone receptor induction and cell proliferation by estrogens and antiestrogens in MCF-7 human breast cancer cells: study with 24 triphenylacrylonitrile derivatives.
Topics: Breast Neoplasms; Cell Division; Cell Line; Estrogen Antagonists; Estrogens; Humans; Phenolsulfonphthalein; Receptors, Progesterone; Stilbenes; Structure-Activity Relationship | 1988 |
Role of specific interactions between protein kinase C and triphenylethylenes in inhibition of the enzyme.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Chromatography, Agarose; Peptide Fragments; Protein Kinase C; Rats; Stilbenes; Tamoxifen | 1988 |
Triphenylethylenes: a new class of protein kinase C inhibitors.
Topics: Animals; Brain; Cells, Cultured; Estrogen Antagonists; Fibroblasts; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Stilbenes; Structure-Activity Relationship; Tamoxifen | 1986 |
Triphenylethylene antiestrogen binding sites (TABS) specificity.
Topics: Animals; Binding Sites; Cholesterol; Estrogen Antagonists; Female; In Vitro Techniques; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, Estrogen; Stilbenes; Structure-Activity Relationship; Tamoxifen; Trifluoperazine | 1987 |
Subcellular and extracellular localization of specific binding sites for triphenylethylene antiestrogens in human breast cancer.
Topics: Binding Sites; Breast Neoplasms; Humans; In Vitro Techniques; Receptors, Drug; Receptors, Estrogen; Stilbenes; Tamoxifen | 1986 |
Estrogenic effect of tamoxifen and its derivatives on the proliferation of MCF7 human breast tumor cells.
Topics: Breast Neoplasms; Cell Division; Cell Line; Culture Media; Estrogens; Female; Humans; Stilbenes; Tamoxifen | 1985 |
Characterization of a triphenylethylene-antiestrogen-binding site on rat serum low density lipoprotein.
Topics: Animals; Binding Sites; Binding, Competitive; Estrogen Antagonists; Female; Kinetics; Lipoproteins, LDL; Male; Protein Binding; Rats; Rats, Inbred Strains; Stilbenes; Tamoxifen | 1983 |
[The search for active antitumor agents among triphenylethylene derivatives].
Topics: Animals; Antineoplastic Agents; Estrogen Antagonists; Rats; Stilbenes | 1995 |
Species specificity of triphenylethylene derivatives and of compounds with a steroidal backbone for human and rat liver antioestrogen binding site (AEBS).
Topics: Animals; Benzofurans; Binding Sites; Binding, Competitive; Estrogen Antagonists; Humans; Mitochondria, Liver; Rats; Rats, Wistar; Regression Analysis; Species Specificity; Stilbenes; Tamoxifen | 1993 |
Relative involvement of protein kinase C and of the estrogen receptor in the cytotoxic action of a population of triphenylethylenes on MCF7 cells as revealed by correspondence factorial (CF) analysis.
Topics: Animals; Binding, Competitive; Breast Neoplasms; Calcium; Cattle; Cell Death; Cell Division; Cytosol; Estradiol; Estrogen Antagonists; Female; Humans; Multivariate Analysis; Phosphatidylserines; Protein Kinase C; Receptors, Estrogen; Stilbenes; Styrenes; Tumor Cells, Cultured | 1993 |
Triphenylethylene antiestrogens induce uterine vascular endothelial growth factor expression via their partial estrogen agonist activity.
Topics: Animals; Blotting, Northern; Clomiphene; Dose-Response Relationship, Drug; Endothelial Growth Factors; Estradiol; Estrogen Antagonists; Estrogens; Female; Lymphokines; Nafoxidine; Ovariectomy; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stilbenes; Tamoxifen; Time Factors; Uterus; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1997 |
Effects of new triphenylethylene platinum(II) complexes on the interaction with phosphatidylcholine liposomes.
Topics: Antineoplastic Agents; Calorimetry, Differential Scanning; Cell Membrane Permeability; Cisplatin; Liposomes; Phosphatidylcholines; Stilbenes; Structure-Activity Relationship | 1998 |
Synthesis and preliminary in vitro cytotoxic activity of novel cisplatin and carboplatin analogues.
Topics: Antineoplastic Agents; Breast Neoplasms; Carboplatin; Cisplatin; Diamines; Female; Humans; In Vitro Techniques; Platinum Compounds; Stilbenes; Tamoxifen; Tumor Cells, Cultured | 1998 |
Cross-resistance of triphenylethylene-type antiestrogens but not ICI 182,780 in tamoxifen-stimulated breast tumors grown in athymic mice.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Stilbenes; Tamoxifen; Time Factors; Toremifene; Tumor Cells, Cultured | 2000 |
Differential SERM activation of the estrogen receptors (ERalpha and ERbeta) at AP-1 sites.
Topics: Cinnamates; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Genes, Regulator; HeLa Cells; Humans; Protein Binding; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Stilbenes; Tamoxifen; Transcription Factor AP-1; Transcription, Genetic | 2001 |
Okadaic acid-sensitive activation of Maxi Cl(-) channels by triphenylethylene antioestrogens in C1300 mouse neuroblastoma cells.
Topics: Animals; Carcinogens; Chloride Channels; Chlorides; Cyclic AMP; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Ion Channel Gating; Mice; Neuroblastoma; Okadaic Acid; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Phosphorylation; Selective Estrogen Receptor Modulators; Signal Transduction; Staurosporine; Stilbenes; Tamoxifen; Toremifene; Tumor Cells, Cultured | 2001 |
Triphenylethylene antiestrogen-induced acute relaxation of mouse duodenal muscle. Possible involvement of Ca2+ channels.
Topics: Animals; Calcium; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Duodenum; Estrogen Receptor Modulators; In Vitro Techniques; Male; Mice; Muscle Relaxation; Stilbenes | 2002 |
Some coumarins and triphenylethene derivatives as inhibitors of human testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD type 3): further studies with tamoxifen on the rat testes microsomal enzyme.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Coumarins; Enzyme Inhibitors; Estrogen Antagonists; Humans; Male; Microsomes; Molecular Structure; Rats; Stilbenes; Structure-Activity Relationship; Testis | 2002 |
[Synthesis of triphenylethylene with aliphatic cyclic moiety and its antagonism on estrogen receptor].
Topics: Animals; Crystallography; Female; Mice; Molecular Conformation; Molecular Structure; Organ Size; Receptors, Estrogen; Stilbenes; Uterus | 2001 |
[Remarks on radiobromo-triphenylethylene and its metabolism after injection into mice in massive doses].
Topics: Animals; Estrous Cycle; Estrus; Ethylenes; Female; Mice; Stilbenes | 1952 |
[The biological properties of ketones in the series of the thiophene isosteres of stilbene and of triphenylethylene].
Topics: Furans; Ketones; Stilbenes; Thiophenes | 1954 |
[Prolonged estrogenic activity of fluorinated derivatives of 1, 2, 2-triphenylethylene].
Topics: Estradiol Congeners; Estrogens; Ethylenes; Stilbenes | 1955 |
[In vitro debromination of triphenylethylene bromide].
Topics: Bromides; In Vitro Techniques; Stilbenes | 1955 |
Anti-inflammatory activity of amidines of substituted triphenylethylenes.
Topics: Amidines; Anti-Inflammatory Agents; Humans; Inflammation; Stilbenes | 1962 |
ANTIGONADOTROPIC ACTIVITY OF SOME SUBSTITUTED TRIPHENYLETHYLENE DERIVATIVES.
Topics: Aniline Compounds; Biphenyl Compounds; Castration; Cycloparaffins; Estrogens; Female; Gonadotropins; Gonadotropins, Pituitary; Humans; Hydrocarbons; Ovary; Pharmacology; Pituitary Gland; Rats; Research; Stilbenes | 1964 |
Lymphoma induction in mice by synthetic estrogens of triphenylethylene type.
Topics: Animals; Contraceptive Agents, Female; Estradiol Congeners; Estrogens; Female; Humans; Lymphoma; Mice; Stilbenes | 1961 |
Chemical constitution and sex-hormone activity: some analogues of triphenylethylene.
Topics: Estradiol Congeners; Estrogens; Gonadal Steroid Hormones; Humans; Stilbenes | 1950 |
[Metabolism of triphenylethylene bromide, observed in the mouse with the aid of radioactive tracers].
Topics: Animals; Bromides; Bromine; Bromine Radioisotopes; Mice; Radioactive Tracers; Radioactivity; Stilbenes; Styrene; Styrenes | 1950 |
Modulation of estrogen receptor transactivation and estrogen-induced gene expression by ormeloxifene-a triphenylethylene derivative.
Topics: Animals; Benzopyrans; Chlorocebus aethiops; COS Cells; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Molecular Structure; Ovariectomy; Rats; Receptors, Progesterone; Response Elements; Stilbenes; Transcriptional Activation; Uterus | 2006 |
Synthesis of 1,1,2-triphenylethylenes and their antiproliferative effect on human cancer cell lines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Stilbenes | 2007 |
Tamoxifen stimulates calcium entry into human platelets.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Calcium; Calcium Signaling; Diethylstilbestrol; Drug Synergism; Estradiol; Estrenes; Estrogen Antagonists; Ethamoxytriphetol; Female; Fulvestrant; Humans; Male; Middle Aged; Molecular Structure; Phosphodiesterase Inhibitors; Pyrrolidinones; Stilbenes; Structure-Activity Relationship; Tamoxifen; Thrombin; Vasopressins | 2007 |
Synthetic oestrogens related to triphenylethylene.
Topics: Contraceptive Agents, Female; Estradiol Congeners; Estrogens; Female; Humans; Stilbenes; Styrene; Styrenes | 1949 |
Synthetic oestrogens related to triphenylethylene.
Topics: Contraceptive Agents, Female; Estradiol Congeners; Estrogens; Female; Humans; Stilbenes; Styrene; Styrenes | 1949 |
Synthetic oestrogens of the triphenylethylene series.
Topics: Contraceptive Agents, Female; Estradiol Congeners; Estrogens; Female; Humans; Stilbenes | 1948 |
Highly active triphenylethylene derivatives.
Topics: Stilbenes; Styrenes | 1947 |
Treatment of prostatic cancer with alpha-bromo-alpha beta. beta-triphenylethylene (Y59).
Topics: Bromides; Bromine; Bromine Compounds; Humans; Male; Neoplasms; Prostatic Neoplasms; Stilbenes | 1947 |
Halogen-substituted oestrogens related to triphenylethylene.
Topics: Estrogens; Halogens; Humans; Stilbenes; Styrenes | 1947 |
Synthesis and characterization of triphenylethylene derivatives with aggregation-induced emission characteristics.
Topics: Fluorescence; Luminescent Measurements; Molecular Structure; Quantum Theory; Stereoisomerism; Stilbenes | 2011 |
Evaluation of the OECD (Q)SAR Application Toolbox for the profiling of estrogen receptor binding affinities.
Topics: Animals; Binding Sites; Chemical Phenomena; Endocrine Disruptors; Flavonoids; Humans; Phthalic Acids; Quantitative Structure-Activity Relationship; Rats; Receptors, Estrogen; Software; Steroids; Stilbenes | 2012 |
Design, synthesis, and anti-tumor activities of novel triphenylethylene-coumarin hybrids, and their interactions with Ct-DNA.
Topics: Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; Cell Proliferation; Coumarins; DNA; Drug Design; Drug Screening Assays, Antitumor; Humans; Intercalating Agents; Neoplasms; Stilbenes | 2013 |
Cytotoxicity and DNA binding property of triphenylethylene-coumarin hybrids with two amino side chains.
Topics: Amino Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Circular Dichroism; Coumarins; DNA; Drug Design; Humans; Stilbenes; Structure-Activity Relationship | 2014 |
Defining the conformation of the estrogen receptor complex that controls estrogen-induced apoptosis in breast cancer.
Topics: Apoptosis; Breast Neoplasms; Crystallography, X-Ray; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Estrogens; Female; Humans; MCF-7 Cells; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Stilbenes | 2014 |
Cytotoxicity and DNA binding property of the dimers of triphenylethylene-coumarin hybrid with one amino side chain.
Topics: Amines; Animals; Antineoplastic Agents; Binding Sites; Cattle; Cell Line, Tumor; Cell Proliferation; Coumarins; Dimerization; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; K562 Cells; MCF-7 Cells; Molecular Structure; Osteoblasts; Stilbenes; Structure-Activity Relationship | 2014 |
Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics.
Topics: Cytotoxins; Enzyme Activation; Estrogen Antagonists; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Lipid Metabolism; Phosphotransferases (Alcohol Group Acceptor); Sphingolipids; Stilbenes; Tamoxifen; Tumor Cells, Cultured | 2015 |
A new Suzuki synthesis of triphenylethylenes that inhibit aromatase and bind to estrogen receptors α and β.
Topics: Aromatase; Aromatase Inhibitors; Binding Sites; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; MCF-7 Cells; Molecular Structure; Protein Binding; Stilbenes; Structure-Activity Relationship | 2016 |
Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Topics: Breast Neoplasms; Cell Proliferation; Cell Survival; Crystallography, X-Ray; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Receptors, Estrogen; Stilbenes; Tamoxifen | 2018 |
Triphenylethylene-Coumarin Hybrid TCH-5c Suppresses Tumorigenic Progression in Breast Cancer Mainly Through the Inhibition of Angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Breast Neoplasms; Carcinogenesis; Coumarins; Female; Humans; Mice, Nude; Neovascularization, Pathologic; Stilbenes | 2019 |
The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Humans; MCF-7 Cells; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Stilbenes; Structure-Activity Relationship | 2020 |
Synthesis of Triphenylethylene-Naphthalimide Conjugates as topoisomerase-IIα inhibitor and HSA binder.
Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Naphthalimides; Poly-ADP-Ribose Binding Proteins; Serum Albumin, Human; Stilbenes; Topoisomerase II Inhibitors | 2021 |
Flexible Etherified and Esterified Triphenylethylene Derivatives and Their Evaluation on ER-positive and Triple-Negative Breast Cancer Cell Lines.
Topics: Breast Neoplasms; Female; Humans; MCF-7 Cells; Stilbenes; Tamoxifen; Triple Negative Breast Neoplasms | 2022 |