Page last updated: 2024-08-17

triphenylethylene and stilbenes

triphenylethylene has been researched along with stilbenes in 64 studies

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-199025 (39.06)18.7374
1990's15 (23.44)18.2507
2000's9 (14.06)29.6817
2010's12 (18.75)24.3611
2020's3 (4.69)2.80

Authors

AuthorsStudies
De Mieri, M; Hamburger, M; Hering, S; Jähne, EA; Raith, M; Rueda, DC; Schöffmann, A1
Desombre, ER; Gatley, SJ; Hughes, A; Li, J; Mease, RC; Pan, ML; Seevers, RE1
Arnstein, HR; Cannon, M; Halliwell, B; Smith, C; Wiseman, H1
Bignon, E; Crastes de Paulet, A; Doré, JC; Gilbert, J; Miquel, JF; Ojasoo, T; Pons, M; Raynaud, JP2
Leclercq, G; Legros, N; McCague, R1
Metzler, M; Schiffmann, D1
Bignon, E; Crastes de Paulet, A; Gilbert, J; Ojasoo, T; Pons, M; Raynaud, JP1
Bignon, E; Gilbert, J; Nishizuka, Y; Pons, M1
Dey, SK; Huet-Hudson, YM1
Clark, JH; Guthrie, S1
Barrera, G; Dianzani, MU; Farina, A; Ferretti, C; Frati, L; Gulino, A; Paradisi, L; Parola, M; Screpanti, I; Vacca, A1
Barrera, G; Dianzani, MU; Farina, A; Ferretti, C; Frati, L; Gulino, A; Screpanti, I; Vacca, A1
Bignon, E; Crastes de Paulet, A; Gilbert, J; Pons, M1
Anderson, BW; O'Brian, CA; Ward, NE1
Liskamp, RM; O'Brian, CA; Solomon, DH; Weinstein, IB1
Clark, JH; Guthrie, SC; Mitchell, WC1
Farina, A; Frati, L; Gulino, A; Modesti, A; Screpanti, I; Vacca, A1
Papendorp, JT; Sonnenschein, C; Soto, AM1
Clark, JH; Guthrie, SC; Winneker, RC1
Grinenko, GS; Kappusheva, LM; Kareva, EN; Savel'eva, GM; Sergeev, PV; Solov'eva, EV1
Blankenstein, MA; Thijssen, JH; van den Koedijk, CD1
Blankenstein, MA; Govers, RM; Thijssen, JH; van den Koedijk, CD1
Chiappetta, C; Hyder, SM; Stancel, GM1
Bérubé, G; Gicquaud, C; Grenier, G1
Bérubé, G; Gaudreault, RC; Séné, A1
De Los Reyes, A; England, G; Jordan, VC; Lee, ES; O'Regan, RM; Schafer, JM; Yao, K1
Clegg, NJ; Scanlan, TS; Weatherman, RV1
Bahamonde, MI; Diaz, M; Hardy, SP; Lock, H; Muñoz, FJ; Posas, F; Valverde, MA1
Díaz, M1
Barrell, KJ; Kirby, A; LE Lain, R; Nicholls, PJ; Saeed, GS; Simons, C; Smith, HJ1
Chu, FM; Guan, MZ; Guo, ZR; Liang, XT; Wang, NG; Xu, BL1
APELGOT, S; CHEUTIN, A; HURST, L; MARS, S1
BUU-HOI, NP; DELOR, J; GLEY, P; NAM, NH; XUONG, ND1
BUU-HOI, NP; CORRE-HURST, L; XUONG, ND1
APELGOT, S; MORIN, GA1
STUCKI, JC; THOMPSON, CR1
BORIS, A; FOX, HH1
NISHIZUKA, Y1
DAVIES, JS; ROBSON, JM; TEBRICH, W1
APELGOT, S; BUU-HOI, NP; COSTEROUSSE, O; DAUDEL, P; LACASSAGNE, A1
Awasthi, S; Blesson, CS; Daverey, A; Dwivedi, A; Kharkwal, G1
Liu, ZL; Wei, Q; Yang, L; Zheng, L; Zhou, B1
Blackmore, PF; Chatterjie, N; Dobrydneva, Y; Fichandler, CE; Fitzgerald, MC; Morrell, MM; Trebley, JP; Weatherman, RV1
TARDOS, W1
FARAHAT, K; ROBSON, JM; TARDOS, W1
CARTER, PR; HEY, DH1
ROBSON, JM; TADROS, W1
BERGER, M; BUN-HOI, NP1
EMMENS, CW1
Chi, ZG; Li, HY; Li, XF; Liu, SW; Xu, BJ; Xu, JR; Zhang, XQ; Zhang, Y; Zhou, W1
Mombelli, E1
Chen, H; Gu, Y; Li, S; Li, X; Wang, K; Yao, Y; Zhao, J; Zhou, L1
Chen, H; Li, S; Li, X; Lv, M; Yao, Y; Zhao, L1
Curpan, R; Jordan, VC; Obiorah, I; Sengupta, S1
Chen, H; Gu, Y; Li, S; Li, X; Lv, M; Tan, G; Wang, K; Yao, Y1
Barth, BM; Cabot, MC; Claxton, DF; Feith, DJ; Fox, TE; Kester, M; Loughran, TP; Morad, SA; Tan, SF1
Cushman, M; Flockhart, DA; Ipe, J; Jin, HS; Liu, J; Lv, W; Skaar, TC; Zhao, LM1
Abderrahman, B; Curpan, RF; Fan, P; Fanning, SW; Greene, GL; Greenland, JA; Jordan, VC; Maximov, PY; Rajan, SS; Rincon, DMQ; Sengupta, S1
Krysan, DJ; Montoya, MC1
Chen, H; Cui, N; Lin, DD; Shen, Y; Shi, JG; Shi, JH; Wang, B; Zhao, MZ; Zheng, L1
Abderrahman, B; Broom, BM; Chen, Y; Curpan, RF; Fan, P; Fanning, SW; Foulds, CE; Greene, GL; Greenland, JA; Han, R; Hawsawi, YM; Jain, A; Jordan, VC; Malovannaya, A; Maximov, PY; Quintana Rincon, DM1
Luxami, V; Paul, K; Rani, S1
Abadi, AH; Ahmed, NS; Hassan, AS; Vollmer, G; Wober, J1

Reviews

2 review(s) available for triphenylethylene and stilbenes

ArticleYear
Speculation on the mechanism of action of triphenylethylene antioestrogens.
    Biochemical pharmacology, 1994, Jun-01, Volume: 47, Issue:11

    Topics: Animals; Binding Sites; Breast Neoplasms; Estradiol; Estrogen Antagonists; Estrogen Replacement Therapy; Humans; Receptors, Estrogen; Stilbenes; Tamoxifen

1994
Repurposing Estrogen Receptor Antagonists for the Treatment of Infectious Disease.
    mBio, 2018, 12-18, Volume: 9, Issue:6

    Topics: Animals; Bacteria; Communicable Diseases; Drug Repositioning; Estrogen Receptor Antagonists; Female; Humans; Mice; Parasites; Stilbenes; Tamoxifen; Toremifene; Viruses

2018

Other Studies

62 other study(ies) available for triphenylethylene and stilbenes

ArticleYear
Identification of dihydrostilbenes in Pholidota chinensis as a new scaffold for GABAA receptor modulators.
    Bioorganic & medicinal chemistry, 2014, Feb-15, Volume: 22, Issue:4

    Topics: Animals; Oocytes; Orchidaceae; Patch-Clamp Techniques; Plant Extracts; Plant Roots; Plant Stems; Protein Subunits; Receptors, GABA-A; Stilbenes; Xenopus laevis

2014
Synthesis, purification and stability of no carrier added radioiodinated 1,1-bis(4-hydroxyphenyl)-2-iodo-2-phenylethylene (IBHPE), a prototype triphenylethylene estrogen-receptor binding radiopharmaceutical.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1991, Volume: 18, Issue:7

    Topics: Aging; Animals; Chromatography, High Pressure Liquid; Drug Stability; Estrogen Antagonists; Female; Rats; Receptors, Estrogen; Stilbenes; Tissue Distribution; Ultracentrifugation; Uterus

1991
The antioxidant action of ketoconazole and related azoles: comparison with tamoxifen and cholesterol.
    Chemico-biological interactions, 1991, Volume: 79, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Cattle; Cholesterol; Ergosterol; Estrogen Antagonists; Ferric Compounds; Iron; Ketoconazole; Lipid Peroxidation; Liposomes; Male; Microsomes, Liver; Phospholipids; Rats; Stilbenes; Tamoxifen

1991
Influence of di- and tri-phenylethylene estrogen/antiestrogen structure on the mechanisms of protein kinase C inhibition and activation as revealed by a multivariate analysis.
    Biochemical pharmacology, 1991, Sep-12, Volume: 42, Issue:7

    Topics: Animals; Binding Sites; Enzyme Activation; Estrogen Antagonists; Models, Molecular; Multivariate Analysis; Protein Kinase C; Rats; Stilbenes; Structure-Activity Relationship; Styrenes

1991
Effect of estrogenic and antiestrogenic triphenylethylene derivatives on progesterone and estrogen receptors levels of MCF-7 cells.
    Biochemical pharmacology, 1991, Oct-09, Volume: 42, Issue:9

    Topics: Animals; Binding, Competitive; Cytosol; Estrogen Antagonists; Estrogens; Phosphorylation; Receptors, Estrogen; Receptors, Progesterone; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured

1991
Structural requirements for the in vitro transformation of Syrian hamster embryo cells by stilbene estrogens and triphenylethylene-type antiestrogens.
    American journal of clinical oncology, 1991, Volume: 14 Suppl 2

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Estrogen Antagonists; Estrogens, Non-Steroidal; Fibrosarcoma; Mesocricetus; Mice; Mice, Nude; Stilbenes; Structure-Activity Relationship

1991
Hydroxylated triphenylacrylonitriles adopt a unique orientation within the binding site of the estrogen receptor.
    Journal of steroid biochemistry, 1990, Aug-14, Volume: 36, Issue:5

    Topics: Animals; Binding Sites; Cattle; Estrogen Antagonists; Female; Hydroxylation; Models, Molecular; Molecular Conformation; Molecular Structure; Receptors, Estrogen; Stilbenes; Structure-Activity Relationship; Uterus

1990
Multiple mechanisms of protein kinase C inhibition by triphenylacrylonitrile antiestrogens.
    FEBS letters, 1990, Oct-01, Volume: 271, Issue:1-2

    Topics: Acrylonitrile; Animals; Binding Sites; Diglycerides; Enzyme Activation; Estrogen Antagonists; Phosphatidylserines; Protein Kinase C; Rats; Stilbenes

1990
Differential effects of ovarian steroids and triphenylethylene compounds on macromolecular uptake and thymidine incorporation in the mouse uterus.
    Journal of steroid biochemistry, 1990, Volume: 35, Issue:1

    Topics: Animals; Capillary Permeability; Clomiphene; DNA; Estradiol; Estriol; Estrogens; Female; Mice; Nitromifene; Progesterone; Serum Albumin, Bovine; Stilbenes; Uterus

1990
Subcellular localization of triphenylethylene antiestrogen binding sites (TABS) in rat liver.
    Journal of steroid biochemistry, 1986, Volume: 25, Issue:5A

    Topics: Animals; Cell Fractionation; Cell Nucleus; Charcoal; Dextrans; Estrogen Antagonists; Female; Liver; Microsomes, Liver; Mitochondria, Liver; Potassium Chloride; Rats; Rats, Inbred Strains; Stilbenes; Tamoxifen

1986
Structure-activity relationships of calmodulin antagonism by triphenylethylene antiestrogens.
    Biochemical pharmacology, 1986, Sep-01, Volume: 35, Issue:17

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Calmodulin; Estradiol; Estrogen Antagonists; Nafoxidine; Stilbenes; Structure-Activity Relationship; Tamoxifen

1986
Calmodulin antagonism and growth-inhibiting activity of triphenylethylene antiestrogens in MCF-7 human breast cancer cells.
    Cancer research, 1986, Volume: 46, Issue:12 Pt 1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Breast Neoplasms; Calmodulin; Cell Division; Cell Line; Cyclic Nucleotide Phosphodiesterases, Type 1; Estrogen Antagonists; Female; Humans; Protein Kinase C; Stilbenes; Tamoxifen; Tetradecanoylphorbol Acetate

1986
Analogies and differences in the modulation of progesterone receptor induction and cell proliferation by estrogens and antiestrogens in MCF-7 human breast cancer cells: study with 24 triphenylacrylonitrile derivatives.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:6

    Topics: Breast Neoplasms; Cell Division; Cell Line; Estrogen Antagonists; Estrogens; Humans; Phenolsulfonphthalein; Receptors, Progesterone; Stilbenes; Structure-Activity Relationship

1988
Role of specific interactions between protein kinase C and triphenylethylenes in inhibition of the enzyme.
    Journal of the National Cancer Institute, 1988, Dec-21, Volume: 80, Issue:20

    Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Chromatography, Agarose; Peptide Fragments; Protein Kinase C; Rats; Stilbenes; Tamoxifen

1988
Triphenylethylenes: a new class of protein kinase C inhibitors.
    Journal of the National Cancer Institute, 1986, Volume: 76, Issue:6

    Topics: Animals; Brain; Cells, Cultured; Estrogen Antagonists; Fibroblasts; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Stilbenes; Structure-Activity Relationship; Tamoxifen

1986
Triphenylethylene antiestrogen binding sites (TABS) specificity.
    Journal of steroid biochemistry, 1987, Volume: 26, Issue:4

    Topics: Animals; Binding Sites; Cholesterol; Estrogen Antagonists; Female; In Vitro Techniques; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, Estrogen; Stilbenes; Structure-Activity Relationship; Tamoxifen; Trifluoperazine

1987
Subcellular and extracellular localization of specific binding sites for triphenylethylene antiestrogens in human breast cancer.
    Biochemical pharmacology, 1986, Nov-01, Volume: 35, Issue:21

    Topics: Binding Sites; Breast Neoplasms; Humans; In Vitro Techniques; Receptors, Drug; Receptors, Estrogen; Stilbenes; Tamoxifen

1986
Estrogenic effect of tamoxifen and its derivatives on the proliferation of MCF7 human breast tumor cells.
    Life sciences, 1985, Jul-29, Volume: 37, Issue:4

    Topics: Breast Neoplasms; Cell Division; Cell Line; Culture Media; Estrogens; Female; Humans; Stilbenes; Tamoxifen

1985
Characterization of a triphenylethylene-antiestrogen-binding site on rat serum low density lipoprotein.
    Endocrinology, 1983, Volume: 112, Issue:5

    Topics: Animals; Binding Sites; Binding, Competitive; Estrogen Antagonists; Female; Kinetics; Lipoproteins, LDL; Male; Protein Binding; Rats; Rats, Inbred Strains; Stilbenes; Tamoxifen

1983
[The search for active antitumor agents among triphenylethylene derivatives].
    Voprosy onkologii, 1995, Volume: 41, Issue:2

    Topics: Animals; Antineoplastic Agents; Estrogen Antagonists; Rats; Stilbenes

1995
Species specificity of triphenylethylene derivatives and of compounds with a steroidal backbone for human and rat liver antioestrogen binding site (AEBS).
    Biochemical pharmacology, 1993, Nov-17, Volume: 46, Issue:10

    Topics: Animals; Benzofurans; Binding Sites; Binding, Competitive; Estrogen Antagonists; Humans; Mitochondria, Liver; Rats; Rats, Wistar; Regression Analysis; Species Specificity; Stilbenes; Tamoxifen

1993
Relative involvement of protein kinase C and of the estrogen receptor in the cytotoxic action of a population of triphenylethylenes on MCF7 cells as revealed by correspondence factorial (CF) analysis.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:3

    Topics: Animals; Binding, Competitive; Breast Neoplasms; Calcium; Cattle; Cell Death; Cell Division; Cytosol; Estradiol; Estrogen Antagonists; Female; Humans; Multivariate Analysis; Phosphatidylserines; Protein Kinase C; Receptors, Estrogen; Stilbenes; Styrenes; Tumor Cells, Cultured

1993
Triphenylethylene antiestrogens induce uterine vascular endothelial growth factor expression via their partial estrogen agonist activity.
    Cancer letters, 1997, Dec-09, Volume: 120, Issue:2

    Topics: Animals; Blotting, Northern; Clomiphene; Dose-Response Relationship, Drug; Endothelial Growth Factors; Estradiol; Estrogen Antagonists; Estrogens; Female; Lymphokines; Nafoxidine; Ovariectomy; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stilbenes; Tamoxifen; Time Factors; Uterus; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1997
Effects of new triphenylethylene platinum(II) complexes on the interaction with phosphatidylcholine liposomes.
    Chemical & pharmaceutical bulletin, 1998, Volume: 46, Issue:9

    Topics: Antineoplastic Agents; Calorimetry, Differential Scanning; Cell Membrane Permeability; Cisplatin; Liposomes; Phosphatidylcholines; Stilbenes; Structure-Activity Relationship

1998
Synthesis and preliminary in vitro cytotoxic activity of novel cisplatin and carboplatin analogues.
    Drug design and discovery, 1998, Volume: 15, Issue:4

    Topics: Antineoplastic Agents; Breast Neoplasms; Carboplatin; Cisplatin; Diamines; Female; Humans; In Vitro Techniques; Platinum Compounds; Stilbenes; Tamoxifen; Tumor Cells, Cultured

1998
Cross-resistance of triphenylethylene-type antiestrogens but not ICI 182,780 in tamoxifen-stimulated breast tumors grown in athymic mice.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:12

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Stilbenes; Tamoxifen; Time Factors; Toremifene; Tumor Cells, Cultured

2000
Differential SERM activation of the estrogen receptors (ERalpha and ERbeta) at AP-1 sites.
    Chemistry & biology, 2001, Volume: 8, Issue:5

    Topics: Cinnamates; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Genes, Regulator; HeLa Cells; Humans; Protein Binding; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Stilbenes; Tamoxifen; Transcription Factor AP-1; Transcription, Genetic

2001
Okadaic acid-sensitive activation of Maxi Cl(-) channels by triphenylethylene antioestrogens in C1300 mouse neuroblastoma cells.
    The Journal of physiology, 2001, Oct-01, Volume: 536, Issue:Pt 1

    Topics: Animals; Carcinogens; Chloride Channels; Chlorides; Cyclic AMP; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Ion Channel Gating; Mice; Neuroblastoma; Okadaic Acid; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Phosphorylation; Selective Estrogen Receptor Modulators; Signal Transduction; Staurosporine; Stilbenes; Tamoxifen; Toremifene; Tumor Cells, Cultured

2001
Triphenylethylene antiestrogen-induced acute relaxation of mouse duodenal muscle. Possible involvement of Ca2+ channels.
    European journal of pharmacology, 2002, Jun-12, Volume: 445, Issue:3

    Topics: Animals; Calcium; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Duodenum; Estrogen Receptor Modulators; In Vitro Techniques; Male; Mice; Muscle Relaxation; Stilbenes

2002
Some coumarins and triphenylethene derivatives as inhibitors of human testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD type 3): further studies with tamoxifen on the rat testes microsomal enzyme.
    Journal of enzyme inhibition and medicinal chemistry, 2002, Volume: 17, Issue:2

    Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Coumarins; Enzyme Inhibitors; Estrogen Antagonists; Humans; Male; Microsomes; Molecular Structure; Rats; Stilbenes; Structure-Activity Relationship; Testis

2002
[Synthesis of triphenylethylene with aliphatic cyclic moiety and its antagonism on estrogen receptor].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2001, Volume: 36, Issue:3

    Topics: Animals; Crystallography; Female; Mice; Molecular Conformation; Molecular Structure; Organ Size; Receptors, Estrogen; Stilbenes; Uterus

2001
[Remarks on radiobromo-triphenylethylene and its metabolism after injection into mice in massive doses].
    Bulletin de la Societe de chimie biologique, 1952, Volume: 34, Issue:10

    Topics: Animals; Estrous Cycle; Estrus; Ethylenes; Female; Mice; Stilbenes

1952
[The biological properties of ketones in the series of the thiophene isosteres of stilbene and of triphenylethylene].
    Bulletin de la Societe de chimie biologique, 1954, Volume: 36, Issue:9

    Topics: Furans; Ketones; Stilbenes; Thiophenes

1954
[Prolonged estrogenic activity of fluorinated derivatives of 1, 2, 2-triphenylethylene].
    Bulletin de la Societe de chimie biologique, 1955, Volume: 37, Issue:7-8

    Topics: Estradiol Congeners; Estrogens; Ethylenes; Stilbenes

1955
[In vitro debromination of triphenylethylene bromide].
    Bulletin de la Societe de chimie biologique, 1955, Volume: 37, Issue:11

    Topics: Bromides; In Vitro Techniques; Stilbenes

1955
Anti-inflammatory activity of amidines of substituted triphenylethylenes.
    Toxicology and applied pharmacology, 1962, Volume: 4

    Topics: Amidines; Anti-Inflammatory Agents; Humans; Inflammation; Stilbenes

1962
ANTIGONADOTROPIC ACTIVITY OF SOME SUBSTITUTED TRIPHENYLETHYLENE DERIVATIVES.
    Archives internationales de pharmacodynamie et de therapie, 1964, Oct-01, Volume: 151

    Topics: Aniline Compounds; Biphenyl Compounds; Castration; Cycloparaffins; Estrogens; Female; Gonadotropins; Gonadotropins, Pituitary; Humans; Hydrocarbons; Ovary; Pharmacology; Pituitary Gland; Rats; Research; Stilbenes

1964
Lymphoma induction in mice by synthetic estrogens of triphenylethylene type.
    Mie medical journal, 1961, Volume: 11

    Topics: Animals; Contraceptive Agents, Female; Estradiol Congeners; Estrogens; Female; Humans; Lymphoma; Mice; Stilbenes

1961
Chemical constitution and sex-hormone activity: some analogues of triphenylethylene.
    British journal of pharmacology and chemotherapy, 1950, Volume: 5, Issue:3

    Topics: Estradiol Congeners; Estrogens; Gonadal Steroid Hormones; Humans; Stilbenes

1950
[Metabolism of triphenylethylene bromide, observed in the mouse with the aid of radioactive tracers].
    Bulletin de la Societe de chimie biologique, 1950, Volume: 32, Issue:3-4

    Topics: Animals; Bromides; Bromine; Bromine Radioisotopes; Mice; Radioactive Tracers; Radioactivity; Stilbenes; Styrene; Styrenes

1950
Modulation of estrogen receptor transactivation and estrogen-induced gene expression by ormeloxifene-a triphenylethylene derivative.
    Steroids, 2006, Volume: 71, Issue:11-12

    Topics: Animals; Benzopyrans; Chlorocebus aethiops; COS Cells; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Molecular Structure; Ovariectomy; Rats; Receptors, Progesterone; Response Elements; Stilbenes; Transcriptional Activation; Uterus

2006
Synthesis of 1,1,2-triphenylethylenes and their antiproliferative effect on human cancer cell lines.
    Anti-cancer drugs, 2007, Volume: 18, Issue:9

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Stilbenes

2007
Tamoxifen stimulates calcium entry into human platelets.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:4

    Topics: Adenosine Diphosphate; Adult; Blood Platelets; Calcium; Calcium Signaling; Diethylstilbestrol; Drug Synergism; Estradiol; Estrenes; Estrogen Antagonists; Ethamoxytriphetol; Female; Fulvestrant; Humans; Male; Middle Aged; Molecular Structure; Phosphodiesterase Inhibitors; Pyrrolidinones; Stilbenes; Structure-Activity Relationship; Tamoxifen; Thrombin; Vasopressins

2007
Synthetic oestrogens related to triphenylethylene.
    Journal of the Chemical Society, 1949, Volume: 27

    Topics: Contraceptive Agents, Female; Estradiol Congeners; Estrogens; Female; Humans; Stilbenes; Styrene; Styrenes

1949
Synthetic oestrogens related to triphenylethylene.
    Journal of the Chemical Society, 1949, Volume: 26

    Topics: Contraceptive Agents, Female; Estradiol Congeners; Estrogens; Female; Humans; Stilbenes; Styrene; Styrenes

1949
Synthetic oestrogens of the triphenylethylene series.
    Journal of the Chemical Society, 1948

    Topics: Contraceptive Agents, Female; Estradiol Congeners; Estrogens; Female; Humans; Stilbenes

1948
Highly active triphenylethylene derivatives.
    Nature, 1947, Jul-05, Volume: 160, Issue:4053

    Topics: Stilbenes; Styrenes

1947
Treatment of prostatic cancer with alpha-bromo-alpha beta. beta-triphenylethylene (Y59).
    Lancet (London, England), 1947, Aug-02, Volume: 2, Issue:6466

    Topics: Bromides; Bromine; Bromine Compounds; Humans; Male; Neoplasms; Prostatic Neoplasms; Stilbenes

1947
Halogen-substituted oestrogens related to triphenylethylene.
    The Journal of endocrinology, 1947, Volume: 5, Issue:3

    Topics: Estrogens; Halogens; Humans; Stilbenes; Styrenes

1947
Synthesis and characterization of triphenylethylene derivatives with aggregation-induced emission characteristics.
    Journal of fluorescence, 2011, Volume: 21, Issue:5

    Topics: Fluorescence; Luminescent Measurements; Molecular Structure; Quantum Theory; Stereoisomerism; Stilbenes

2011
Evaluation of the OECD (Q)SAR Application Toolbox for the profiling of estrogen receptor binding affinities.
    SAR and QSAR in environmental research, 2012, Volume: 23, Issue:1-2

    Topics: Animals; Binding Sites; Chemical Phenomena; Endocrine Disruptors; Flavonoids; Humans; Phthalic Acids; Quantitative Structure-Activity Relationship; Rats; Receptors, Estrogen; Software; Steroids; Stilbenes

2012
Design, synthesis, and anti-tumor activities of novel triphenylethylene-coumarin hybrids, and their interactions with Ct-DNA.
    Bioorganic & medicinal chemistry letters, 2013, Sep-01, Volume: 23, Issue:17

    Topics: Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; Cell Proliferation; Coumarins; DNA; Drug Design; Drug Screening Assays, Antitumor; Humans; Intercalating Agents; Neoplasms; Stilbenes

2013
Cytotoxicity and DNA binding property of triphenylethylene-coumarin hybrids with two amino side chains.
    Bioorganic & medicinal chemistry letters, 2014, Feb-01, Volume: 24, Issue:3

    Topics: Amino Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Circular Dichroism; Coumarins; DNA; Drug Design; Humans; Stilbenes; Structure-Activity Relationship

2014
Defining the conformation of the estrogen receptor complex that controls estrogen-induced apoptosis in breast cancer.
    Molecular pharmacology, 2014, Volume: 85, Issue:5

    Topics: Apoptosis; Breast Neoplasms; Crystallography, X-Ray; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Estrogens; Female; Humans; MCF-7 Cells; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Stilbenes

2014
Cytotoxicity and DNA binding property of the dimers of triphenylethylene-coumarin hybrid with one amino side chain.
    Bioorganic & medicinal chemistry letters, 2014, Jul-01, Volume: 24, Issue:13

    Topics: Amines; Animals; Antineoplastic Agents; Binding Sites; Cattle; Cell Line, Tumor; Cell Proliferation; Coumarins; Dimerization; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; K562 Cells; MCF-7 Cells; Molecular Structure; Osteoblasts; Stilbenes; Structure-Activity Relationship

2014
Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics.
    Biochimica et biophysica acta, 2015, Volume: 1851, Issue:7

    Topics: Cytotoxins; Enzyme Activation; Estrogen Antagonists; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Lipid Metabolism; Phosphotransferases (Alcohol Group Acceptor); Sphingolipids; Stilbenes; Tamoxifen; Tumor Cells, Cultured

2015
A new Suzuki synthesis of triphenylethylenes that inhibit aromatase and bind to estrogen receptors α and β.
    Bioorganic & medicinal chemistry, 2016, 11-01, Volume: 24, Issue:21

    Topics: Aromatase; Aromatase Inhibitors; Binding Sites; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; MCF-7 Cells; Molecular Structure; Protein Binding; Stilbenes; Structure-Activity Relationship

2016
Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
    Molecular pharmacology, 2018, Volume: 94, Issue:2

    Topics: Breast Neoplasms; Cell Proliferation; Cell Survival; Crystallography, X-Ray; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Receptors, Estrogen; Stilbenes; Tamoxifen

2018
Triphenylethylene-Coumarin Hybrid TCH-5c Suppresses Tumorigenic Progression in Breast Cancer Mainly Through the Inhibition of Angiogenesis.
    Anti-cancer agents in medicinal chemistry, 2019, Volume: 19, Issue:10

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Breast Neoplasms; Carcinogenesis; Coumarins; Female; Humans; Mice, Nude; Neovascularization, Pathologic; Stilbenes

2019
The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells.
    Molecular pharmacology, 2020, Volume: 98, Issue:1

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Humans; MCF-7 Cells; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Stilbenes; Structure-Activity Relationship

2020
Synthesis of Triphenylethylene-Naphthalimide Conjugates as topoisomerase-IIα inhibitor and HSA binder.
    ChemMedChem, 2021, 06-07, Volume: 16, Issue:11

    Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Naphthalimides; Poly-ADP-Ribose Binding Proteins; Serum Albumin, Human; Stilbenes; Topoisomerase II Inhibitors

2021
Flexible Etherified and Esterified Triphenylethylene Derivatives and Their Evaluation on ER-positive and Triple-Negative Breast Cancer Cell Lines.
    ChemMedChem, 2022, 04-05, Volume: 17, Issue:7

    Topics: Breast Neoplasms; Female; Humans; MCF-7 Cells; Stilbenes; Tamoxifen; Triple Negative Breast Neoplasms

2022