tripdiolide has been researched along with tripchlorolide* in 1 studies
1 other study(ies) available for tripdiolide and tripchlorolide
| Article | Year |
|---|---|
Male antifertility compounds from Tripterygium wilfordii Hook f.
Extracts of the Chinese medicinal plant, Tripterygium wilfordii, cause reversible infertility in male animals. Sub-fractionation studies have now revealed that the plant extracts contain a number of compounds which are potent antifertility agents in male mammals, including the diterpenes triptolide and tripdiolide and an isomer of the latter. A triptolide, 12,13-chlorohydrin, which is a transformation product formed reversibly by interaction of triptolide with HCl, was also found to be active. Topics: Animals; Biological Assay; Chromatography, High Pressure Liquid; Diterpenes; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Epoxy Compounds; Fertility; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Organ Size; Phenanthrenes; Rats; Serial Extraction; Sperm Count; Sperm Motility; Spermatocidal Agents; Tablets; Testis; Weight Gain | 1993 |