tripchlorolide has been researched along with phenanthrenes in 38 studies
| Studies (tripchlorolide) | Trials (tripchlorolide) | Recent Studies (post-2010) (tripchlorolide) | Studies (phenanthrenes) | Trials (phenanthrenes) | Recent Studies (post-2010) (phenanthrenes) |
|---|---|---|---|---|---|
| 39 | 0 | 7 | 7,618 | 110 | 3,211 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (39.47) | 18.2507 |
| 2000's | 15 (39.47) | 29.6817 |
| 2010's | 7 (18.42) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, XT; Wang, HB; Yu, DQ; Zhang, DM | 1 |
| He, LY; Yu, DQ; Zhang, DM | 1 |
| Lu, X | 1 |
| Yao, Q; Zhang, N | 1 |
| Bi, Z; Li, X; Liu, T; Yang, J | 1 |
| Bi, Z; Li, X; Zhang, L | 1 |
| Yao, QP; Zhang, NZ | 1 |
| Den, Y; Huang, Y; Xue, S; Ye, W | 1 |
| Amor, SR; Belenguer, A; Matlin, SA; Pearce, CM; Qian, SZ; Sanders, JK; Stacey, VE; Xu, Y; Zhang, JW | 1 |
| Yao, Q; Zeng, Z; Zhang, N | 1 |
| Wang, N; Zuo, X | 1 |
| Zeng, X; Zhang, N | 1 |
| Cao, L; Gu, ZP; Mao, BY; Qian, SZ; Wang, ZP; Xu, Y; You, GD | 1 |
| Zeng, XJ; Zhang, NZ | 1 |
| Qiu, HB; Yang, Y; Zhou, SX | 1 |
| Cheng, XX; Han, JS; He, QH; Li, FQ; Liang, XB; Wang, XH; Wang, XM; Xue, B | 1 |
| Gao, Y; Li, L; Li, X; Lin, J; Su, Y | 1 |
| Cheng, XX; Han, JS; Huang, M; Li, FQ; Wang, XM | 1 |
| Jiang, MR; Li, YC; Wu, JR; Yang, Y | 1 |
| Dong, Y; Guo, Y; Jiang, Y; Song, Q; Yu, M | 1 |
| Ren, Y; Wu, JR; Xiong, L | 1 |
| Ren, Y; Wu, JR | 1 |
| Jin, Y; Wei, Y; Wu, JR; Xiong, L; Yang, Y | 1 |
| Jin, Y; Leung, WK; Sung, JJ; Wu, JR | 1 |
| Bai, J; Chen, Y; Li, B; Li, Z; Wang, L; Yang, G | 1 |
| Bai, L; Chen, SD; Gu, J; Hong, Z; Pan, J; Wang, G; Zhang, S | 1 |
| Smith, PF | 1 |
| Chen, LM; Chen, XC; Huang, HP; Huang, TW; Pan, XD; Ye, QY; Zhang, J; Zhu, YG | 2 |
| Chen, XC; Pan, XD | 1 |
| Chen, XC; Lin, N; Pan, XD; Wu, M; Zhang, J; Zhu, YG | 1 |
| Chen, L; Chen, X; Huang, Z; Li, Z; Lin, T; Liu, Q; Wu, F | 1 |
| Chen, AQ; Chen, XC; Lin, N; Pan, XD; Wu, M; Zhang, J; Zhu, YG | 1 |
| Chen, X; Dai, X; Lin, N; Lu, J; Pan, X; Shen, H; Zeng, Y; Zhang, J; Zhou, M; Zhu, Y | 1 |
| Chen, XC; Huang, TW; Kang, DY; Pan, XD; Zeng, YQ; Zhang, J | 1 |
| Chen, LM; Chen, XC; Lin, N; Pan, XD; Shi, YQ; Zhang, J; Zhu, YG | 1 |
| Hu, JC; Yao, XL; Yao, ZH; Zhang, SF; Zhang, Y | 1 |
| Chen, LM; Chen, YQ; Huang, PT; Lin, XH; Song, TJ | 1 |
2 review(s) available for tripchlorolide and phenanthrenes
| Article | Year |
|---|---|
Inflammation in Parkinson's disease: an update.
Topics: Animals; Anti-Inflammatory Agents; Benzoates; Bridged-Ring Compounds; Diterpenes; Drug Evaluation, Preclinical; Glucosides; Humans; Inflammation; Monoterpenes; Parkinson Disease; Phenanthrenes; Purines | 2008 |
[Advances in the study of immunopharmacological effects and mechanisms of extracts of Tripterygium wilfordii Hook. f. in neuroimmunologic disorders].
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Humans; Neurodegenerative Diseases; NF-kappa B; Phenanthrenes; Structure-Activity Relationship; Tripterygium | 2008 |
36 other study(ies) available for tripchlorolide and phenanthrenes
| Article | Year |
|---|---|
[Structure modification of triptolide, a diterpenoid from Tripterygium wilfordii].
Topics: Animals; Antibody Formation; Diterpenes; Drugs, Chinese Herbal; Lymphocyte Activation; Mice; Phenanthrenes; Structure-Activity Relationship | 1992 |
[Quantitative analysis of tripchlorolide in pharmaceutical preparation by RP-HPLC].
Topics: Capsules; Chromatography, High Pressure Liquid; Diterpenes; Phenanthrenes | 1992 |
[The isolation and structure of tripchlorolide (T4) from Tripterygium wilfordii].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Diterpenes; Drugs, Chinese Herbal; Glucosides; Molecular Conformation; Phenanthrenes; Tripterygium | 1990 |
[Effects of tripchlorolide (T4) of Tripterygium wilfordii Hook on the proliferation of peripheral blood mononuclear cells of rheumatoid arthritis patients].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cell Division; Diterpenes; Female; Humans; Leukocytes, Mononuclear; Male; Phenanthrenes | 1994 |
[The experimental study of immunosuppressive effect of tripchlorolide on the cardiac allograft rats].
Topics: Animals; Diterpenes; Drugs, Chinese Herbal; Female; Graft Rejection; Heart Transplantation; Immunosuppressive Agents; Male; Phenanthrenes; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1994 |
[Inhibitory effects of monomer T4 from Tripterygium wilfordii hook on cultured mesangial cells proliferation and IL-1 production].
Topics: Animals; Cell Division; Cells, Cultured; Diterpenes; Drugs, Chinese Herbal; Glomerular Mesangium; Immunosuppressive Agents; Interleukin-1; Male; Mice; Mice, Inbred BALB C; Phenanthrenes | 1994 |
[Effects of tripchlorolide (T4) of Tripterygium wilfordii hook on the production of prostaglandin E2 by synovial cells of rheumatoid arthritis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cells, Cultured; Dinoprostone; Diterpenes; Drugs, Chinese Herbal; Female; Humans; Male; Middle Aged; Phenanthrenes; Synovial Membrane; Tripterygium | 1994 |
Antispermatogenic effect of Tripterygium wilfordii and tripchlorolide (T4) on rat gametogenesis and spermatozoa.
Topics: Animals; Antispermatogenic Agents; Diterpenes; Drugs, Chinese Herbal; Male; Phenanthrenes; Rats; Rats, Wistar; Spermatogenesis; Spermatozoa; Tripterygium | 1994 |
Male antifertility compounds from Tripterygium wilfordii Hook f.
Topics: Animals; Biological Assay; Chromatography, High Pressure Liquid; Diterpenes; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Epoxy Compounds; Fertility; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Organ Size; Phenanthrenes; Rats; Serial Extraction; Sperm Count; Sperm Motility; Spermatocidal Agents; Tablets; Testis; Weight Gain | 1993 |
[Effect of tripchlorolide (T4) of Tripterygium wilfordii Hook on the production of endothelin-1 by endothelial cells of human umbilical vein].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Diterpenes; Drugs, Chinese Herbal; Endothelins; Endothelium, Vascular; Humans; Immunosuppressive Agents; Phenanthrenes; Tripterygium; Umbilical Veins | 1995 |
[Study on antifertility mechanisms of tripchlorolide (T4)].
Topics: Animals; Diterpenes; Epididymis; Glutathione; Hyaluronoglucosaminidase; Male; Phenanthrenes; Rats; Rats, Wistar; Spermatocidal Agents; Testis | 1995 |
[The effects of a single active ingredient (T4) of Tripterygium Wilfordii Hook on the production of tumor necrosis factor by the peripheral blood mononuclear cells and synovium cells of rheumatoid arthritis patients].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cells, Cultured; Diterpenes; Drugs, Chinese Herbal; Female; Humans; Immunosuppressive Agents; Leukocytes, Mononuclear; Male; Phenanthrenes; Synovial Membrane; Tripterygium; Tumor Necrosis Factor-alpha | 1996 |
Effects of tripchlorolide on the epididymides and testes of rats.
Topics: Animals; Body Weight; Contraceptive Agents, Male; Diterpenes; Epididymis; Fertility; Male; Organ Size; Phenanthrenes; Rats; Rats, Sprague-Dawley; Sperm Motility; Testis | 1999 |
[Effects of tripchlorolide (T4) of Tripterygium Wilfordii Hook on the production of immunoglobulins by peripheral blood mononuclear cells and by synovial cells of rheumatoid arthritis patients in vitro].
Topics: Adult; Arthritis, Rheumatoid; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Humans; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; Leukocytes, Mononuclear; Male; Phenanthrenes; Synovial Membrane | 1997 |
Effects of tripcholorolide on inflammatory reaction of mouse alveolar macrophages in vitro.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cell Separation; Dexamethasone; Diterpenes; Interleukin-10; Interleukin-6; Macrophages, Alveolar; Magnoliopsida; Male; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenanthrenes; Plants, Medicinal; RNA, Messenger; Tripterygium; Tumor Necrosis Factor-alpha | 2000 |
Neurotrophic and neuroprotective effects of tripchlorolide, an extract of Chinese herb Tripterygium wilfordii Hook F, on dopaminergic neurons.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Axotomy; Brain-Derived Neurotrophic Factor; Cell Division; Cells, Cultured; Corpus Striatum; Diterpenes; Dopamine; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Homovanillic Acid; Immunohistochemistry; Immunosuppressive Agents; Medial Forebrain Bundle; Neurites; Neurons; Neuroprotective Agents; Phenanthrenes; Rats; Rats, Sprague-Dawley; Recovery of Function; RNA, Messenger; Tripterygium | 2003 |
[Effects of cyclosporin A combined with T4 on collagen IV production, coll alpha 1 (IV) mRNA and TGF beta 1 mRNA expression in cultured human mesangial cells].
Topics: Cells, Cultured; Collagen Type IV; Cyclosporine; Diterpenes; Drug Synergism; Drugs, Chinese Herbal; Glomerular Mesangium; Humans; Phenanthrenes; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 1999 |
[Protective effect of tripchlorolide on dopaminergic neurons in partially lesioned rat model of Parkinson's disease].
Topics: Animals; Behavior, Animal; Brain; Corpus Striatum; Diterpenes; Dopamine; Drugs, Chinese Herbal; Interleukin-2; Male; Neurons; Neuroprotective Agents; Parkinson Disease; Phenanthrenes; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2002 |
c-Myc degradation induced by DNA damage results in apoptosis of CHO cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; CHO Cells; Cricetinae; Cysteine Endopeptidases; Diterpenes; DNA Damage; Multienzyme Complexes; Phenanthrenes; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-myc; Ubiquitin | 2003 |
[Effect of Tripterygium Wilfordii Hook T4 monomer on proliferation and interleukin-6 production of synovial fibroblasts of patients with rheumatoid arthritis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cell Division; Cells, Cultured; Diterpenes; Drug Antagonism; Female; Fibroblasts; Humans; Interleukin-1; Interleukin-6; Male; Middle Aged; Phenanthrenes; Synovial Membrane; Tripterygium | 2000 |
Induction of mitochondrion-mediated apoptosis of CHO cells by tripchlorolide.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; CHO Cells; Cricetinae; Cytochromes c; Diterpenes; Drugs, Chinese Herbal; Humans; Mitochondria; Phenanthrenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2 | 2003 |
Differential activation of intra-S-phase checkpoint in response to tripchlorolide and its effects on DNA replication.
Topics: Animals; Cell Cycle Proteins; Checkpoint Kinase 1; CHO Cells; Cricetinae; Diterpenes; DNA Damage; DNA Replication; Phenanthrenes; Phosphorylation; Protein Kinases; S Phase | 2004 |
Differential regulation of survivin by p53 contributes to cell cycle dependent apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; CHO Cells; Cricetinae; Cricetulus; Diterpenes; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation; HeLa Cells; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Oncogene Proteins, Viral; Phenanthrenes; Survivin; Tumor Suppressor Protein p53 | 2005 |
p53-independent pRB degradation contributes to a drug-induced apoptosis in AGS cells.
Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Comet Assay; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytosol; Diterpenes; DNA Damage; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Flow Cytometry; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, Dominant; Humans; Mitochondria; Phenanthrenes; Plasmids; Proteasome Endopeptidase Complex; Retinoblastoma Protein; Stomach Neoplasms; Tumor Suppressor Protein p53 | 2005 |
Monitoring of the conversion from triptolide to tripchlorolide in Triptergium wilfordii by micellar electrokinetic caillary chromatography.
Topics: Calibration; Chromatography, Micellar Electrokinetic Capillary; Diterpenes; Epoxy Compounds; Hydrogen-Ion Concentration; Methanol; Molecular Structure; Phenanthrenes; Plant Extracts; Plant Roots; Reproducibility of Results; Sodium Dodecyl Sulfate; Temperature; Time Factors; Tripterygium | 2005 |
Tripchlorolide protects against MPTP-induced neurotoxicity in C57BL/6 mice.
Topics: Animals; Cell Death; Chromatography, High Pressure Liquid; Diterpenes; Dopamine; Immunohistochemistry; Locomotion; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neostriatum; Nerve Degeneration; Nerve Fibers; Neuroprotective Agents; Phenanthrenes; Postural Balance; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase | 2007 |
Neuroprotective role of tripchlorolide on inflammatory neurotoxicity induced by lipopolysaccharide-activated microglia.
Topics: Animals; Blotting, Western; Cell Culture Techniques; Cell Line; Cell Survival; Culture Media, Conditioned; Cyclooxygenase 2; Dinoprostone; Diterpenes; Interleukin-1beta; Lipopolysaccharides; Mice; Microglia; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Nitric Oxide; Nitric Oxide Synthase Type II; Phenanthrenes; Tumor Necrosis Factor-alpha | 2008 |
Tripchlorolide protects neuronal cells from microglia-mediated beta-amyloid neurotoxicity through inhibiting NF-kappaB and JNK signaling.
Topics: Amyloid beta-Peptides; Animals; Brain; Cell Line; Cells, Cultured; Diterpenes; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Microglia; Neuroimmunomodulation; Neurons; Neuroprotective Agents; NF-kappa B p50 Subunit; Peptide Fragments; Phenanthrenes | 2009 |
[Involvement of Wnt/beta-catenin signaling in tripchlorolide protecting against oligomeric beta-amyloid-(1-42)-induced neuronal apoptosis].
Topics: Amyloid beta-Peptides; Animals; Apoptosis; beta Catenin; Cell Survival; Cells, Cultured; Cerebral Cortex; Diterpenes; Female; Fetus; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Neurons; Neuroprotective Agents; Peptide Fragments; Phenanthrenes; Phosphorylation; Plants, Medicinal; Pregnancy; Rats; Rats, Sprague-Dawley; Signal Transduction; Tripterygium; Wnt Proteins | 2010 |
Tripchlorolide induces cell death in lung cancer cells by autophagy.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Autophagy; Cell Death; Cell Line, Tumor; Cell Survival; Diterpenes; Humans; Lung Neoplasms; Phenanthrenes; Signal Transduction; Up-Regulation | 2012 |
Tripchlorolide improves age-associated cognitive deficits by reversing hippocampal synaptic plasticity impairment and NMDA receptor dysfunction in SAMP8 mice.
Topics: Aging; Animals; Cognition; Cognition Disorders; Diterpenes; Hippocampus; Male; Maze Learning; Mice; Neuronal Plasticity; Phenanthrenes; Receptors, N-Methyl-D-Aspartate; Synapses | 2014 |
Tripchlorolide improves cognitive deficits by reducing amyloid β and upregulating synapse-related proteins in a transgenic model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Diterpenes; Humans; Immunosuppressive Agents; Maze Learning; Mice; Mice, Transgenic; Phenanthrenes; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Psychomotor Performance; Synapses; TOR Serine-Threonine Kinases | 2015 |
Tripchlorolide ameliorates experimental autoimmune encephalomyelitis by down-regulating ERK1/2-NF-κB and JAK/STAT signaling pathways.
Topics: Animals; Demyelinating Diseases; Diterpenes; Down-Regulation; Encephalomyelitis, Autoimmune, Experimental; Female; Immunosuppressive Agents; Inflammation; Janus Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; Phenanthrenes; Signal Transduction; Spinal Cord; STAT1 Transcription Factor | 2015 |
Tripchlorolide Attenuates β-amyloid Generation via Suppressing PPARγ-Regulated BACE1 Activity in N2a/APP695 Cells.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cell Line, Tumor; Cell Survival; Diterpenes; Humans; Mice; Mice, Transgenic; Phenanthrenes; PPAR gamma; Protein Biosynthesis; RNA, Messenger; Transcription, Genetic | 2016 |
Tripchlorolide May Improve Spatial Cognition Dysfunction and Synaptic Plasticity after Chronic Cerebral Hypoperfusion.
Topics: Animals; Brain Ischemia; Cognitive Dysfunction; Dendritic Spines; Diterpenes; Hippocampus; Male; Neuronal Plasticity; Phenanthrenes; Rats; Rats, Sprague-Dawley; Spatial Learning | 2019 |
T4 reduces cisplatin resistance by inhibiting AEG-1 gene expression in lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cisplatin; Diterpenes; Drug Resistance, Neoplasm; Gene Expression; Humans; Lung Neoplasms; Membrane Proteins; Phenanthrenes; RNA-Binding Proteins; Transcription Factors | 2022 |