Page last updated: 2024-08-16

trimipramine and clomipramine

trimipramine has been researched along with clomipramine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19907 (25.00)18.7374
1990's4 (14.29)18.2507
2000's7 (25.00)29.6817
2010's9 (32.14)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Blakely, RD; Groshan, K; Richelson, E; Tatsumi, M1
Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Bellman, K; Knegtel, RM; Settimo, L1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL1
Kocher, R1
Baba, O; Fujiwara, J; Hanaoka, M; Ishino, H; Sasaki, K1
Detaevernier, MR; Dryon, L; Massart, DL1
Baumann, P; Cuendet, C; Eap, CB1
Jones, RS; Olpe, HR1
Lader, M1
Abernethy, DR; Greenblatt, DJ; Shader, RI1
Inagaki, M; Katsumoto, T; Nanba, E; Ohno, K; Suehiro, S; Takeshita, K1
Kumazawa, T; Lee, XP; Sato, K; Suzuki, O1
Fernandez-Belda, F; Fortea, I; Plenge-Tellechea, F; Soler, F1
Booth-Genthe, CL; Grimm, SW; Guo, J; Linnenbach, AJ; Zhou, D1
Hosseiny Davarani, SS; Memarian, E; Moazami, HR; Nojavan, S1
Alexovič, M; Nojavan, S; Shokri, A; Tabani, H; Tizro, S; Varanusupakul, P1
Ciszek, R; Ekolle Ndode-Ekane, X; Hämäläinen, E; Hiltunen, M; Hujo, M; Kansanen, E; Levonen, AL; Lipponen, A; Natunen, T; Paananen, J; Pitkänen, A; Poulsen, D; Tohka, J1

Reviews

2 review(s) available for trimipramine and clomipramine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Combined use of tricyclic antidepressants and monoamine oxidase inhibitors.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:9 Pt 2

    Topics: Adult; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Drug Therapy, Combination; Female; Fever; Humans; Male; Monoamine Oxidase Inhibitors; Psychiatric Status Rating Scales; Tranylcypromine; Trimipramine

1983

Trials

1 trial(s) available for trimipramine and clomipramine

ArticleYear
Combined use of tricyclic antidepressants and monoamine oxidase inhibitors.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:9 Pt 2

    Topics: Adult; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Drug Therapy, Combination; Female; Fever; Humans; Male; Monoamine Oxidase Inhibitors; Psychiatric Status Rating Scales; Tranylcypromine; Trimipramine

1983

Other Studies

26 other study(ies) available for trimipramine and clomipramine

ArticleYear
Pharmacological profile of antidepressants and related compounds at human monoamine transporters.
    European journal of pharmacology, 1997, Dec-11, Volume: 340, Issue:2-3

    Topics: Antidepressive Agents; Brain; Carrier Proteins; Cell Line; Dopamine Plasma Membrane Transport Proteins; Humans; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Radioligand Assay; Serotonin Plasma Membrane Transport Proteins; Symporters; Synaptosomes

1997
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship

1999
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
    RSC medicinal chemistry, 2022, Feb-23, Volume: 13, Issue:2

    Topics:

2022
[The treatment of chronic pain symptoms with psychotropic drugs (author's transl)].
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1976, Volume: 9, Issue:6

    Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bone Diseases; Clomipramine; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Neoplasms; Neuralgia; Pain; Palliative Care; Promazine; Trimipramine

1976
Effect of flupenthixol on depression with special reference to combination use with tricyclic antidepressants. An uncontrolled pilot study with 45 patients.
    Acta psychiatrica Scandinavica, 1976, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Clomipramine; Depression; Drug Evaluation; Drug Therapy, Combination; Female; Flupenthixol; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Pilot Projects; Thioxanthenes; Trimipramine

1976
The separation of some tricyclic antidepressants by high-performance liquid chromatography.
    Journal of chromatography, 1976, Nov-17, Volume: 128, Issue:1

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Microchemistry; Nortriptyline; Protriptyline; Trimipramine

1976
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:2

    Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine

1988
An increase in sensitivity of rat cingulate cortical neurones to substance P occurs following withdrawal of chronic administration of antidepressant drugs.
    British journal of pharmacology, 1984, Volume: 81, Issue:4

    Topics: Action Potentials; Animals; Antidepressive Agents; Clomipramine; Desipramine; Diazepam; Drug Resistance; Fluphenazine; Gyrus Cinguli; Male; Neurons; Rats; Substance P; Time Factors; Trimipramine; Zimeldine

1984
Trimipramine kinetics and absolute bioavailability: use of gas-liquid chromatography with nitrogen-phosphorus detection.
    Clinical pharmacology and therapeutics, 1984, Volume: 35, Issue:3

    Topics: Administration, Oral; Adult; Aged; Biological Availability; Chromatography, Gas; Clomipramine; Dibenzazepines; Female; Humans; Infusions, Parenteral; Kinetics; Male; Middle Aged; Trimipramine

1984
Lysosomal glycosphingolipid storage in chloroquine-induced alpha-galactosidase-deficient human endothelial cells with transformation by simian virus 40: in vitro model of Fabry disease.
    Acta neuropathologica, 1993, Volume: 85, Issue:3

    Topics: Cell Transformation, Viral; Chloroquine; Clomipramine; Endothelium, Vascular; Fabry Disease; Galactosidases; Glycosphingolipids; Humans; Lysosomes; Microscopy, Electron; Simian virus 40; Trimipramine

1993
Detection of tricyclic antidepressants in whole blood by headspace solid-phase microextraction and capillary gas chromatography.
    Journal of chromatographic science, 1997, Volume: 35, Issue:7

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Humans; Imipramine; Male; Rats; Rats, Wistar; Sodium Hydroxide; Trimipramine; Water

1997
Clomipramine and related structures as inhibitors of the skeletal sarcoplasmic reticulum Ca2+ pump.
    Journal of bioenergetics and biomembranes, 2000, Volume: 32, Issue:2

    Topics: Adenosine Triphosphate; Animals; Antidepressive Agents, Tricyclic; Calcium; Calcium-Transporting ATPases; Clomipramine; Desipramine; Enzyme Inhibitors; Imipramine; Magnesium; Muscle, Skeletal; Phosphorylation; Rabbits; Sarcoplasmic Reticulum; Trimipramine

2000
Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:5

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biocatalysis; Clomipramine; Enzyme Inhibitors; Glucuronic Acid; Glucuronides; Glucuronosyltransferase; Humans; Imipramine; Kinetics; Microsomes, Liver; Nicotine; Recombinant Proteins; Sapogenins; Trimipramine

2010
Electromembrane extraction through a virtually rotating supported liquid membrane.
    Electrophoresis, 2016, Volume: 37, Issue:2

    Topics: Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Chemical Fractionation; Clomipramine; Electrochemical Techniques; Electrodes; Equipment Design; Humans; Limit of Detection; Membranes, Artificial; Rotation; Trimipramine; Urinalysis; Verapamil; Wastewater; Water Pollutants, Chemical; Water Purification

2016
Evaluation of dispersive liquid-liquid microextraction by coupling with green-based agarose gel-electromembrane extraction: An efficient method to the tandem extraction of basic drugs from biological fluids.
    Talanta, 2019, Jul-01, Volume: 199

    Topics: Chromatography, Gas; Clomipramine; Gels; Humans; Hydrogen-Ion Concentration; Liquid Phase Microextraction; Sepharose; Trimipramine

2019
In Vitro and In Vivo Pipeline for Validation of Disease-Modifying Effects of Systems Biology-Derived Network Treatments for Traumatic Brain Injury-Lessons Learned.
    International journal of molecular sciences, 2019, Oct-29, Volume: 20, Issue:21

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Brain Injuries, Traumatic; Cell Line; Clomipramine; Coculture Techniques; Cytokines; Disease; Gene Expression; In Vitro Techniques; Ionomycin; Machine Learning; Male; Microglia; Neurons; Neuroprotection; Neuroprotective Agents; NF-E2-Related Factor 2; Nitrites; Rats; Sirolimus; Systems Biology; Transcriptome; Trimipramine; Tumor Necrosis Factor-alpha; Up-Regulation

2019