Page last updated: 2024-08-16

trimipramine and amitriptyline

trimipramine has been researched along with amitriptyline in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199012 (31.58)18.7374
1990's8 (21.05)18.2507
2000's9 (23.68)29.6817
2010's8 (21.05)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Gozalbes, R; Pineda-Lucena, A1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL1
Boudouresque, G; Bourhis, A; Fondarai, J; Pellet, W; Ponzio, J; Spitalier, JM1
Baba, O; Fujiwara, J; Hanaoka, M; Ishino, H; Sasaki, K1
Detaevernier, MR; Dryon, L; Massart, DL1
Boulton, AA; Yu, PH1
Tyber, MA1
Casas Carnicero, J; Fernández de la Gandara, F; Velasco Martin, A1
Caille, G; Cournoyer, G; de Montigny, C; Elie, R; Langlois, R; le Morvan, P; Ouellette, J1
Baumann, P; Cuendet, C; Eap, CB1
Vajda, L1
Tunkl, E1
Planche, R1
Caillé, G; Cournoyer, G; de Montigny, C; Langlois, R; Morissette, R1
Kline, NS1
Robins, E; Welner, A; Welner, Z1
Court, F; Fuke, C; Pounder, DJ; Sadler, DW1
Löwenhielm, CG; Malmvik, J; Melander, A1
Degen, J; Fischer, W; Höxter, G; Pintar, P; Seiberling, M; Steinhauer, HB; Wölke, E1
Kumazawa, T; Lee, XP; Sato, K; Suzuki, O1
Hardens, M; Nuijten, MJ; Souêtre, E1
Djonlagic, H; Djonlagic, I; Dodt, C; Kibbel, T; Suefke, S1
Chadwick, W; Oelofsen, W; Roux, S; van de Venter, M; Wilson, G1
Ackl, N; Hatzinger, M; Held, K; Holsboer, F; Holsboer-Trachsler, E; Ising, M; Kaschka, W; Kasper, S; Konstantinidis, A; Künzel, HE; Sonntag, A; Steiger, A; Uhr, M; Yassouridis, A1
Hajak, G; Kleinjung, T; Landgrebe, M; Langguth, B; Wittmann, M1
Booth-Genthe, CL; Grimm, SW; Guo, J; Linnenbach, AJ; Zhou, D1
Clark, MS; Jamieson, B; Smith, PO1
Baldo, P; Cecco, S; Doree, C; McFerran, D; Molin, P1

Reviews

3 review(s) available for trimipramine and amitriptyline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Principles of antidepressant therapy and results obtained with Hungarian thymoleptics in hospitalized psychiatric patients.
    Therapia Hungarica (English edition), 1974, Volume: 22, Issue:3

    Topics: Amitriptyline; Antidepressive Agents; Anxiety; Depression; Electroconvulsive Therapy; Humans; Methotrimeprazine; Tachycardia; Tranquilizing Agents; Trimipramine

1974
Antidepressants for patients with tinnitus.
    The Cochrane database of systematic reviews, 2012, Sep-12, Issue:9

    Topics: Amitriptyline; Antidepressive Agents; Depression; Humans; Nortriptyline; Paroxetine; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Tinnitus; Trazodone; Trimipramine

2012

Trials

6 trial(s) available for trimipramine and amitriptyline

ArticleYear
A comparative double-blind controlled study of trimipramine and amitriptyline in major depression: lack of correlation with 5-hydroxytryptamine reuptake blockade.
    Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:6

    Topics: Adult; Aged; Amitriptyline; Blood Pressure; Clinical Trials as Topic; Depressive Disorder; Dexamethasone; Dibenzazepines; Double-Blind Method; Electrocardiography; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Random Allocation; Serotonin Antagonists; Trimipramine; Tryptophan

1987
Lithium carbonate addition in tricyclic antidepressant-resistant unipolar depression. Correlations with the neurobiologic actions of tricyclic antidepressant drugs and lithium ion on the serotonin system.
    Archives of general psychiatry, 1983, Volume: 40, Issue:12

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Desipramine; Doxepin; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Lithium; Lithium Carbonate; Male; Middle Aged; Neurons; Psychiatric Status Rating Scales; Serotonin; Trimipramine

1983
A controlled comparison of trimipramine and amitriptyline.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:3

    Topics: Adult; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Dibenzazepines; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Psychological Tests; Trimipramine

1982
Effect of tricyclic antidepressants on individual symptoms.
    The Journal of clinical psychiatry, 1980, Volume: 41, Issue:9

    Topics: Affective Disorders, Psychotic; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Humans; Imipramine; Protriptyline; Psychotropic Drugs; Trimipramine

1980
[Comparative study of the pharmacokinetics of amitriptyline oxide and trimipramine after single administration in healthy male probands and patients with renal failure].
    Medizinische Klinik (Munich, Germany : 1983), 1993, Mar-15, Volume: 88, Issue:3

    Topics: Adult; Aged; Amitriptyline; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Middle Aged; Nortriptyline; Trimipramine

1993
Outcome in delusional depression comparing trimipramine monotherapy with a combination of amitriptyline and haloperidol--a double-blind multicenter trial.
    Journal of psychiatric research, 2009, Volume: 43, Issue:7

    Topics: Adrenocorticotropic Hormone; Adult; Amitriptyline; Anti-Dyskinesia Agents; Antidepressive Agents, Tricyclic; Corticotropin-Releasing Hormone; Delusions; Depressive Disorder; Dexamethasone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Electroencephalography; Female; Haloperidol; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Middle Aged; Pituitary-Adrenal System; Psychiatric Status Rating Scales; Psychomotor Agitation; Treatment Outcome; Trimipramine

2009

Other Studies

29 other study(ies) available for trimipramine and amitriptyline

ArticleYear
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship

1999
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
    RSC medicinal chemistry, 2022, Feb-23, Volume: 13, Issue:2

    Topics:

2022
Pain infirmity and psychotropic drugs in oncology.
    Pain, 1978, Volume: 5, Issue:3

    Topics: Activities of Daily Living; Amitriptyline; Dose-Response Relationship, Drug; Humans; Methotrimeprazine; Neoplasm Metastasis; Neoplasms; Pain, Intractable; Phenothiazines; Psychotropic Drugs; Sulpiride; Trimipramine

1978
Effect of flupenthixol on depression with special reference to combination use with tricyclic antidepressants. An uncontrolled pilot study with 45 patients.
    Acta psychiatrica Scandinavica, 1976, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Clomipramine; Depression; Drug Evaluation; Drug Therapy, Combination; Female; Flupenthixol; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Pilot Projects; Thioxanthenes; Trimipramine

1976
The separation of some tricyclic antidepressants by high-performance liquid chromatography.
    Journal of chromatography, 1976, Nov-17, Volume: 128, Issue:1

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Microchemistry; Nortriptyline; Protriptyline; Trimipramine

1976
Effect of trimipramine, an atypical tricyclic antidepressant, on the activities of various enzymes involved in the metabolism of biogenic amines.
    Progress in neuro-psychopharmacology & biological psychiatry, 1990, Volume: 14, Issue:3

    Topics: Adrenal Glands; Amitriptyline; Animals; Aromatic-L-Amino-Acid Decarboxylases; Arylsulfotransferase; Biogenic Amines; Catechol O-Methyltransferase; Cattle; Dibenzazepines; Dopamine beta-Hydroxylase; Kinetics; Liver; Male; Monoamine Oxidase; Phenylalanine Hydroxylase; Phenylethanolamine N-Methyltransferase; Rats; Rats, Inbred Strains; Trimipramine; Tyrosine 3-Monooxygenase; Tyrosine Transaminase

1990
Lithium carbonate augmentation therapy in fibromyalgia.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1990, Nov-01, Volume: 143, Issue:9

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Female; Fibromyalgia; Humans; Lithium; Lithium Carbonate; Middle Aged; Trimipramine

1990
Effects of antidepressants on alcohol-induced gastric mucosal injury in rats.
    Methods and findings in experimental and clinical pharmacology, 1989, Volume: 11, Issue:10

    Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpheniramine; Cimetidine; Ethanol; Female; Gastric Mucosa; Maprotiline; Mianserin; Rats; Rats, Inbred Strains; Stomach Ulcer; Trimipramine

1989
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:2

    Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine

1988
Clinical study of Sapilent and of Teperin used alone or in combination.
    Therapia Hungarica (English edition), 1973, Volume: 21, Issue:3-4

    Topics: Adjustment Disorders; Adult; Aged; Amitriptyline; Dibenzazepines; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Trimipramine

1973
[Long-term use of 200 mg Dogmatil. Apropos of 13 cases].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1984, Mar-22, Volume: 60, Issue:13

    Topics: Adult; Amitriptyline; Antipsychotic Agents; Bipolar Disorder; Borderline Personality Disorder; Drug Evaluation; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Middle Aged; Neurotic Disorders; Paranoid Disorders; Schizophrenia; Sulpiride; Time Factors; Trifluperidol; Trimipramine

1984
Drug accumulation and elimination in Calliphora vicina larvae.
    Forensic science international, 1995, Feb-28, Volume: 71, Issue:3

    Topics: Amitriptyline; Animals; Diptera; Humans; Larva; Postmortem Changes; Temazepam; Trazodone; Trimipramine

1995
Antidepressants in suicide: differences in fatality and drug utilisation.
    European journal of clinical pharmacology, 1994, Volume: 46, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents; Autopsy; Drug Overdose; Female; Humans; Lofepramine; Male; Middle Aged; Suicide; Sweden; Trimipramine

1994
Detection of tricyclic antidepressants in whole blood by headspace solid-phase microextraction and capillary gas chromatography.
    Journal of chromatographic science, 1997, Volume: 35, Issue:7

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Humans; Imipramine; Male; Rats; Rats, Wistar; Sodium Hydroxide; Trimipramine; Water

1997
A Markov process analysis comparing the cost effectiveness of maintenance therapy with citalopram versus standard therapy in major depression.
    PharmacoEconomics, 1995, Volume: 8, Issue:2

    Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Citalopram; Cost-Benefit Analysis; Decision Support Techniques; Depressive Disorder; Doxepin; Germany; Humans; Long-Term Care; Markov Chains; Models, Economic; Recurrence; Trimipramine

1995
Heart rate variability reveals risk of arrhythmias after intoxication with antidepressants.
    Intensive care medicine, 2007, Volume: 33, Issue:1

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Heart Rate; Humans; Male; Risk Factors; Suicide, Attempted; Trimipramine

2007
Shifts in metabolic parameters surrounding glucose homoeostasis resulting from tricyclic antidepressant therapy: implications of insulin resistance?
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Blood Glucose; Cell Line; Glucose; Glyburide; Glycogen; Hindlimb; Homeostasis; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulysin; Kidney; Liver; Male; Muscle, Skeletal; Rats; Rats, Wistar; Trimipramine

2007
Persistent tinnitus induced by tricyclic antidepressants.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:8

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy; Depressive Disorder, Major; Humans; Male; Tinnitus; Trimipramine

2010
Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:5

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biocatalysis; Clomipramine; Enzyme Inhibitors; Glucuronic Acid; Glucuronides; Glucuronosyltransferase; Humans; Imipramine; Kinetics; Microsomes, Liver; Nicotine; Recombinant Proteins; Sapogenins; Trimipramine

2010
FPIN's clinical inquiries: Antidepressants for the treatment of insomnia in patients with depression.
    American family physician, 2011, Nov-01, Volume: 84, Issue:9

    Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Dose-Response Relationship, Drug; Doxepin; Evidence-Based Medicine; Humans; Mianserin; Mirtazapine; Practice Guidelines as Topic; Sleep Initiation and Maintenance Disorders; Trazodone; Trimipramine

2011