trimethyloxamine and glycerol

trimethyloxamine has been researched along with glycerol in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (24.24)18.2507
2000's15 (45.45)29.6817
2010's9 (27.27)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Daruwala, R; Meganathan, R1
Cotter, PA; Gunsalus, RP; Park, SJ1
Prusiner, SB; Tatzelt, J; Welch, WJ1
Brown, CR; Hong-Brown, LQ; Welch, WJ1
Tamarappoo, BK; Verkman, AS1
Bertram, EM; Ghumman, B; Watts, TH1
Bai, C; Biwersi, J; Matthay, MA; Verkman, AS1
Chakrabartty, A; Fraser, PE; Huang, TH; Yang, DS; Yip, CM1
Burrows, JA; Perlmutter, DH; Willis, LK1
Anderson, CF; Capp, MW; Courtenay, ES; Record, MT1
Bichet, DG; Bouvier, M; Morello, JP; Petäjä-Repo, UE1
Chebotareva, NA; Harding, SE; Winzor, DJ1
Driedzic, WR; Ewart, KV; Richards, RC; Treberg, JR; Wilson, CE1
Kanazawa, I; Shibasaki, F; Shoji, S; Yoshida, H; Yoshizawa, T1
Nihei, H; Ohashi, T; Sasaki, S; Uchida, K; Uchida, S1
Millard, CB; Newstead, S; Roth, E; Shin, I; Shnyrov, VL; Silman, I; Weiner, L1
Kumar, R; Serrette, JM; Thompson, EB1
Csermely, P; Papp, E1
Hegde, ML; Rao, KS1
Olsen, SN; Ramløv, H; Westh, P1
Rau, DC; Stanley, C1
Leandro, J; Leandro, P; Nascimento, C; Tavares de Almeida, I1
Krywka, C; Paulus, M; Royer, C; Sternemann, C; Tolan, M; Winter, R1
Agard, DA; Bolen, DW; Krukenberg, KA; Rosgen, J; Street, TO1
Braverman, N; Chen, L; Jiralerspong, S; Snowden, A; Steinberg, S; Zhang, R1
Fertala, A; Gawron, K; Jensen, DA; Steplewski, A1
Caves, MS; Derham, BK; Freedman, RB; Jezek, J1
Chakrabarti, P; Chakravarty, D; Chatterjee, T; Dey, S; Pal, A; Saha, RP1
Attri, P; Choi, EH; Kaushik, N; Kaushik, NK1
Agrawal, A; Chakraborty, K; Chakraborty, S; Ghosh, B; Krishnan, V; Mabalirajan, U; Maity, S; Makhija, L; Rehman, R1
Coughlin, DJ; Gezzi, NL; Long, GM; Modi, PM; Woluko, KN1
Chi, MC; Lan, YG; Lin, LL; Lin, MG; Lo, HF; Wang, TF1
Timson, DJ1

Reviews

2 review(s) available for trimethyloxamine and glycerol

ArticleYear
Pharmacological chaperones: a new twist on receptor folding.
    Trends in pharmacological sciences, 2000, Volume: 21, Issue:12

    Topics: Animals; Cryoprotective Agents; Cystic Fibrosis; Diabetes Insipidus, Nephrogenic; Dimethyl Sulfoxide; Endoplasmic Reticulum; Glycerol; Humans; Methylamines; Molecular Chaperones; Mutation; Oxidants; Protein Folding

2000
The roles and applications of chaotropes and kosmotropes in industrial fermentation processes.
    World journal of microbiology & biotechnology, 2020, Jun-08, Volume: 36, Issue:6

    Topics: Alcohols; Amino Acids, Diamino; Bacillus subtilis; Biofuels; Bioreactors; Butanols; Ethanol; Fermentation; Genes, Bacterial; Genes, Fungal; Glycerol; Methylamines; Protein Structure, Secondary; Saccharomyces cerevisiae; Sulfides; Urea; Water; Yeasts; Zymomonas

2020

Other Studies

31 other study(ies) available for trimethyloxamine and glycerol

ArticleYear
Dimethyl sulfoxide reductase is not required for trimethylamine N-oxide reduction in Escherichia coli.
    FEMS microbiology letters, 1991, Oct-15, Volume: 67, Issue:3

    Topics: Anaerobiosis; Culture Media; Escherichia coli; Glycerol; Iron-Sulfur Proteins; Kinetics; Methylamines; Mutation; Oxidation-Reduction; Oxidoreductases

1991
Regulation of malate dehydrogenase (mdh) gene expression in Escherichia coli in response to oxygen, carbon, and heme availability.
    Journal of bacteriology, 1995, Volume: 177, Issue:22

    Topics: 2,2'-Dipyridyl; Aerobiosis; Anaerobiosis; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carbon; Culture Media; Escherichia coli; Escherichia coli Proteins; Fumarates; Gene Expression Regulation, Bacterial; Glycerol; Heme; Iron Chelating Agents; Iron-Sulfur Proteins; Malate Dehydrogenase; Methylamines; Oxidants; Oxygen; Recombinant Fusion Proteins; Repressor Proteins

1995
Chemical chaperones interfere with the formation of scrapie prion protein.
    The EMBO journal, 1996, Dec-02, Volume: 15, Issue:23

    Topics: Animals; Brain; Cell Line; Dimethyl Sulfoxide; Glycerol; Kinetics; Methylamines; Mice; Molecular Chaperones; Neuroblastoma; Phospholipases; Protein Folding; Protein Structure, Secondary; PrPSc Proteins; Reference Values; Scrapie; Solubility; Tumor Cells, Cultured

1996
Correcting temperature-sensitive protein folding defects.
    The Journal of clinical investigation, 1997, Mar-15, Volume: 99, Issue:6

    Topics: Animals; Cell Line; Deuterium Oxide; Glycerol; Ligases; Methylamines; Mutation; Protein Folding; Proto-Oncogene Proteins pp60(c-src); Rats; Temperature; Tumor Suppressor Protein p53; Ubiquitin-Activating Enzymes; Ubiquitin-Protein Ligases

1997
Defective aquaporin-2 trafficking in nephrogenic diabetes insipidus and correction by chemical chaperones.
    The Journal of clinical investigation, 1998, May-15, Volume: 101, Issue:10

    Topics: Animals; Aquaporin 2; Aquaporin 6; Aquaporins; Cell Fractionation; Cell Membrane Permeability; CHO Cells; Cricetinae; Diabetes Insipidus, Nephrogenic; Dimethyl Sulfoxide; Glycerol; Humans; Immunohistochemistry; Ion Channels; Kidney; Methylamines; Molecular Chaperones; Oocytes; Transfection; Water; Xenopus

1998
Chemical chaperones enhance superantigen and conventional antigen presentation by HLA-DM-deficient as well as HLA-DM-sufficient antigen-presenting cells and enhance IgG2a production in vivo.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Oct-01, Volume: 161, Issue:7

    Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Antigen Presentation; Antigen-Presenting Cells; Cell Line; Dimethyl Sulfoxide; Endosomes; Enterotoxins; Female; Glycerol; Haptens; Hemocyanins; Histocompatibility Antigens Class II; HLA-D Antigens; Humans; Immunoglobulin G; Methylamines; Mice; Mice, Inbred C57BL; Protein Biosynthesis; Staphylococcus aureus; Superantigens

1998
A mouse model to test the in vivo efficacy of chemical chaperones.
    Journal of pharmacological and toxicological methods, 1998, Volume: 40, Issue:1

    Topics: Animals; Blood Chemical Analysis; Cells, Cultured; Female; Glycerol; Half-Life; Hematocrit; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Methylamines; Mice; Molecular Chaperones; Oxidants; Protein Binding; Spectrophotometry, Ultraviolet

1998
Manipulating the amyloid-beta aggregation pathway with chemical chaperones.
    The Journal of biological chemistry, 1999, Nov-12, Volume: 274, Issue:46

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Circular Dichroism; Fluorescent Dyes; Glycerol; Humans; Methylamines; Microscopy, Atomic Force; Microscopy, Electron; Molecular Chaperones; Peptide Fragments; Protein Conformation; Protein Folding; Protein Structure, Secondary; Solubility; Spectrometry, Fluorescence

1999
Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Feb-15, Volume: 97, Issue:4

    Topics: Administration, Oral; alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Animals; Cell Line; Emphysema; Glycerol; Humans; Liver; Lung; Methylamines; Mice; Mice, Transgenic; Mutation; Phenylbutyrates; Protein Folding; Temperature

2000
Vapor pressure osmometry studies of osmolyte-protein interactions: implications for the action of osmoprotectants in vivo and for the interpretation of "osmotic stress" experiments in vitro.
    Biochemistry, 2000, Apr-18, Volume: 39, Issue:15

    Topics: Animals; Betaine; Biopolymers; Cattle; Cell Division; Cytoplasm; Dialysis; Escherichia coli; Glutamates; Glycerol; Methylamines; Osmolar Concentration; Pressure; Proline; Serum Albumin; Solutions; Thermodynamics; Trehalose; Water

2000
Ultracentrifugal studies of the effect of molecular crowding by trimethylamine N-oxide on the self-association of muscle glycogen phosphorylase b.
    European journal of biochemistry, 2001, Volume: 268, Issue:3

    Topics: Animals; Cryoprotective Agents; Ethylene Glycol; Glycerol; Hydrogen-Ion Concentration; Methylamines; Models, Chemical; Models, Statistical; Muscle, Skeletal; Phosphorylases; Protein Binding; Rabbits; Sucrose; Thermodynamics; Ultracentrifugation

2001
The freeze-avoidance response of smelt Osmerus mordax: initiation and subsequent suppression of glycerol, trimethylamine oxide and urea accumulation.
    The Journal of experimental biology, 2002, Volume: 205, Issue:Pt 10

    Topics: Acclimatization; Animals; Body Temperature; Freezing; Glycerol; Liver; Methylamines; Osmolar Concentration; Salmoniformes; Seasons; Temperature; Urea

2002
Chemical chaperones reduce aggregate formation and cell death caused by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch.
    Neurobiology of disease, 2002, Volume: 10, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ataxin-3; Cell Line; Cricetinae; Dimethyl Sulfoxide; Glutathione; Glycerol; Humans; Machado-Joseph Disease; Mesocricetus; Methylamines; Nerve Tissue Proteins; Nuclear Proteins; Peptide Fragments; Peptides; Protein Conformation; Protein Folding; Recombinant Fusion Proteins; Repressor Proteins; Transfection

2002
Intracellular mislocalization of mutant podocin and correction by chemical chaperones.
    Histochemistry and cell biology, 2003, Volume: 119, Issue:3

    Topics: Cell Line, Transformed; Dimethyl Sulfoxide; Endoplasmic Reticulum; Glycerol; Humans; Intracellular Signaling Peptides and Proteins; Kidney Glomerulus; Membrane Proteins; Methylamines; Mutation, Missense; Protein Conformation; Protein Transport; Solvents; Stress Fibers; Transfection

2003
Stabilization of a metastable state of Torpedo californica acetylcholinesterase by chemical chaperones.
    Protein science : a publication of the Protein Society, 2003, Volume: 12, Issue:10

    Topics: Acetylcholinesterase; Algorithms; Anilino Naphthalenesulfonates; Animals; Anthracenes; Calorimetry, Differential Scanning; Catalysis; Circular Dichroism; Cross-Linking Reagents; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Enzyme Stability; Glutathione; Glycerol; Hot Temperature; Hydrolysis; Kinetics; Magnesium; Methylamines; Models, Theoretical; Perylene; Protein Conformation; Protein Denaturation; Spectrometry, Fluorescence; Sulfhydryl Reagents; Sulfinic Acids; Thermodynamics; Torpedo; Trypsin

2003
Osmolyte-induced folding enhances tryptic enzyme activity.
    Archives of biochemistry and biophysics, 2005, Apr-01, Volume: 436, Issue:1

    Topics: Catalysis; Chymotrypsin; Enzyme Activation; Glycerol; Kinetics; Methylamines; Osmotic Pressure; Protein Denaturation; Protein Folding; Spectrometry, Fluorescence; Time Factors; Trypsin

2005
Chemical chaperones: mechanisms of action and potential use.
    Handbook of experimental pharmacology, 2006, Issue:172

    Topics: Animals; Enzyme Inhibitors; Glycerol; Humans; Methylamines; Molecular Chaperones; Phenylbutyrates; Protein Folding

2006
DNA induces folding in alpha-synuclein: understanding the mechanism using chaperone property of osmolytes.
    Archives of biochemistry and biophysics, 2007, Aug-01, Volume: 464, Issue:1

    Topics: alpha-Synuclein; Animals; Betaine; Cattle; DNA; DNA, Circular; DNA, Single-Stranded; Glycerol; Methylamines; Models, Biological; Molecular Chaperones; Neurodegenerative Diseases; Protein Structure, Secondary; Sarcosine; Taurine

2007
Effects of osmolytes on hexokinase kinetics combined with macromolecular crowding: test of the osmolyte compatibility hypothesis towards crowded systems.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2007, Volume: 148, Issue:2

    Topics: Betaine; Buffers; Catalysis; Fungal Proteins; Glycerol; Hexokinase; Kinetics; Methylamines; Models, Chemical; Osmotic Pressure; Protein Binding; Serum Albumin, Bovine; Sodium Chloride; Urea; Water

2007
Measuring the interaction of urea and protein-stabilizing osmolytes with the nonpolar surface of hydroxypropylcellulose.
    Biochemistry, 2008, Jun-24, Volume: 47, Issue:25

    Topics: Algorithms; Betaine; Cellulose; Glycerol; Hydrophobic and Hydrophilic Interactions; Methylamines; Models, Chemical; Organic Chemicals; Osmotic Pressure; Proteins; Scattering, Radiation; Sorbitol; Temperature; Thermodynamics; Urea; X-Rays

2008
Modulation of the activity of newly synthesized human phenylalanine hydroxylase mutant proteins by low-molecular-weight compounds.
    The protein journal, 2008, Volume: 27, Issue:6

    Topics: Animals; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Enzymologic; Glycerol; Humans; Methylamines; Mutant Proteins; Phenylalanine Hydroxylase; Phenylbutyrates; Phenylketonurias; Recombinant Fusion Proteins; Temperature

2008
Effect of osmolytes on pressure-induced unfolding of proteins: a high-pressure SAXS study.
    Chemphyschem : a European journal of chemical physics and physical chemistry, 2008, Dec-22, Volume: 9, Issue:18

    Topics: Glycerol; Methylamines; Micrococcal Nuclease; Pressure; Protein Conformation; Protein Denaturation; Protein Stability; Scattering, Small Angle; Solutions; Temperature; Urea; X-Ray Diffraction

2008
Osmolyte-induced conformational changes in the Hsp90 molecular chaperone.
    Protein science : a publication of the Protein Society, 2010, Volume: 19, Issue:1

    Topics: Adenylyl Imidodiphosphate; Betaine; Escherichia coli Proteins; Glycerol; HSP90 Heat-Shock Proteins; Methylamines; Models, Molecular; Osmosis; Protein Conformation; Sarcosine; Scattering, Small Angle; Urea; X-Ray Diffraction

2010
Recovery of PEX1-Gly843Asp peroxisome dysfunction by small-molecule compounds.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Mar-23, Volume: 107, Issue:12

    Topics: Adenosine Triphosphatases; Amino Acid Substitution; ATPases Associated with Diverse Cellular Activities; Betaine; Cells, Cultured; Drug Evaluation, Preclinical; Genes, Reporter; Glycerol; Green Fluorescent Proteins; Humans; Membrane Proteins; Methylamines; Mutation, Missense; Peroxisome-Targeting Signal 1 Receptor; Peroxisomes; Protein Folding; Receptors, Cytoplasmic and Nuclear; Zellweger Syndrome

2010
Reducing the effects of intracellular accumulation of thermolabile collagen II mutants by increasing their thermostability in cell culture conditions.
    Biochemical and biophysical research communications, 2010, May-28, Volume: 396, Issue:2

    Topics: Apoptosis; Cell Culture Techniques; Collagen Type II; Glycerol; Hot Temperature; Humans; Methylamines; Mutation; Osteochondrodysplasias; Protein Folding; Protein Stability

2010
Thermal inactivation of uricase (urate oxidase): mechanism and effects of additives.
    Biochemistry, 2013, Jan-22, Volume: 52, Issue:3

    Topics: Anilino Naphthalenesulfonates; Candida; Chromatography, Gel; Circular Dichroism; Enzyme Stability; Excipients; Fluorometry; Fungal Proteins; Glycerol; Hot Temperature; Hydrophobic and Hydrophilic Interactions; Kinetics; Methylamines; Protein Binding; Protein Denaturation; Protein Structure, Secondary; Recombinant Proteins; Urate Oxidase

2013
Protein l-isoaspartyl-O-methyltransferase of Vibrio cholerae: interaction with cofactors and effect of osmolytes on unfolding.
    Biochimie, 2013, Volume: 95, Issue:4

    Topics: Coenzymes; Glycerol; Guanidine; Methylamines; Models, Molecular; Osmosis; Protein Conformation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Unfolding; S-Adenosylmethionine; Solvents; Stress, Physiological; Thermodynamics; Tryptophan; Vibrio cholerae

2013
A preliminary study of the effect of DBD plasma and osmolytes on T98G brain cancer and HEK non-malignant cells.
    Molecules (Basel, Switzerland), 2013, Apr-25, Volume: 18, Issue:5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cryoprotective Agents; Glycerol; HEK293 Cells; Humans; Methylamines; Osmosis; Sucrose; Sweetening Agents

2013
Chemical chaperones mitigate experimental asthma by attenuating endoplasmic reticulum stress.
    American journal of respiratory cell and molecular biology, 2014, Volume: 50, Issue:5

    Topics: Airway Remodeling; Animals; Asthma; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Glycerol; Inflammation; Lung; Male; Methylamines; Mice; Mice, Inbred BALB C; Molecular Chaperones; Phenylbutyrates; Protein Folding; Trehalose; Unfolded Protein Response

2014
Elevated osmolytes in rainbow smelt: the effects of urea, glycerol and trimethylamine oxide on muscle contractile properties.
    The Journal of experimental biology, 2016, Volume: 219, Issue:Pt 7

    Topics: Animals; Cold Temperature; Cryoprotective Agents; Glycerol; Methylamines; Muscle Contraction; Muscle Fibers, Fast-Twitch; Osmeriformes; Urea

2016
Protective Effect of Biological Osmolytes against Heat- and Chaotropic Agent-Induced Denaturation of
    Journal of microbiology and biotechnology, 2018, Sep-28, Volume: 28, Issue:9

    Topics: Bacillus licheniformis; Escherichia coli; gamma-Glutamyltransferase; Glycerol; Guanidine; Hot Temperature; Methylamines; Osmolar Concentration; Protein Denaturation; Protein Stability; Protein Structure, Secondary; Recombinant Proteins; Sorbitol; Spectrometry, Fluorescence; Sucrose; Urea

2018