trimethyloxamine and gamma-butyrobetaine

trimethyloxamine has been researched along with gamma-butyrobetaine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (13.33)18.2507
2000's0 (0.00)29.6817
2010's9 (60.00)24.3611
2020's4 (26.67)2.80

Authors

AuthorsStudies
Rebouche, CJ1
Chenard, CA; Rebouche, CJ1
Cirule, H; Dambrova, M; Grinberga, S; Gustina, D; Kuka, J; Liepins, J; Liepinsh, E; Loza, E; Makrecka-Kuka, M; Pugovics, O; Zharkova-Malkova, O1
Buffa, JA; Culley, MK; DiDonato, JA; Gregory, JC; Hazen, SL; Koeth, RA; Levison, BS; Li, L; Lusis, AJ; Org, E; Smith, JD; Tang, WHW; Wang, Z; Wu, Y1
Dambrova, M; Grinberga, S; Hartmane, D; Konrade, I; Latkovskis, G; Liepinsh, E; Pugovics, O; Sevostjanovs, E; Strele, I1
Abbas, A; Aukrust, P; Berge, RK; Bjerkeli, V; Gregersen, I; Halvorsen, B; Holm, S; Hov, JE; Karlsen, TH; Kummen, M; Reier-Nilsen, F; Russell, D; Skagen, K; Skjelland, M; Svardal, A; Trøseid, M; Ueland, T1
Berge, RK; Hov, JR; Lappegård, KT; Nestvold, TK; Svardal, A; Thoresen, H; Trøseid, M1
Broniowska, K; Levy, HL; Murali, SG; Nair, N; Ney, DM; Rohr, F; Stroup, BM1
Bartlett, D; Cody, DB; Copeland, MF; Culley, MK; Dai, HJ; DiDonato, JA; Fu, X; Garcia-Garcia, JC; Gu, X; Hazen, SL; Kirsop, J; Koeth, RA; Lam-Galvez, BR; Levison, BS; Li, L; Li, XS; Tang, WHW; Wang, Z; Wu, Y1
Andreassen, AK; Arora, S; Aukrust, P; Berge, RK; Broch, K; Dellgren, G; Gude, E; Gullestad, L; Hov, JR; Karason, K; Mayerhofer, CCK; Svardal, A; Trøseid, M; Ueland, T1
Acikgoz, A; Berge, RK; Bjørndal, B; Caliskan Guzelce, E; Eyupoglu, ND; Svardal, A; Uyanik, E; Yildiz, BO1
Chen, L; Chen, Y; Fan, D; Zhao, M; Zheng, L1
Bernieh, D; Cassambai, S; Heaney, LM; Israr, MZ; Jones, DJL; Ng, LL; Salzano, A; Suzuki, T; Yazaki, Y1
de Oliveira Otto, MC; Fretts, A; Hazen, SL; Lai, HTM; Lee, Y; Lemaitre, RN; Li, XS; Lopez, O; Mozaffarian, D; Nemet, I; Newman, AB; Siscovick, DS; Tang, WHW; Wang, M; Wang, Z1
Dong, E; Gao, J; Huang, M; Ji, L; Li, C; Wang, DW; Wang, Y; Wei, H; Wu, J; Zhang, Q; Zhao, C; Zhao, M; Zheng, L1

Trials

2 trial(s) available for trimethyloxamine and gamma-butyrobetaine

ArticleYear
Metabolomic Markers of Essential Fatty Acids, Carnitine, and Cholesterol Metabolism in Adults and Adolescents with Phenylketonuria.
    The Journal of nutrition, 2018, 02-01, Volume: 148, Issue:2

    Topics: Adolescent; Adult; Amino Acids; Betaine; Biomarkers; Carnitine; Caseins; Cholesterol; Cross-Over Studies; Dietary Supplements; Erythrocytes; Fasting; Fatty Acids; Fatty Acids, Essential; Female; Gastrointestinal Microbiome; Humans; Lipid Metabolism; Male; Metabolomics; Methylamines; Middle Aged; Peptide Fragments; Phenylketonurias

2018
l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans.
    The Journal of clinical investigation, 2019, 01-02, Volume: 129, Issue:1

    Topics: Animals; Atherosclerosis; Betaine; Carnitine; Clostridiales; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Mice; Pilot Projects; Vegans

2019

Other Studies

13 other study(ies) available for trimethyloxamine and gamma-butyrobetaine

ArticleYear
Quantitative estimation of absorption and degradation of a carnitine supplement by human adults.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:12

    Topics: Absorption; Administration, Oral; Adult; Betaine; Carnitine; Chromatography, Ion Exchange; Feces; Humans; Male; Methylamines; Scintillation Counting

1991
Metabolic fate of dietary carnitine in human adults: identification and quantification of urinary and fecal metabolites.
    The Journal of nutrition, 1991, Volume: 121, Issue:4

    Topics: Adult; Betaine; Biotransformation; Carnitine; Chromatography, Ion Exchange; Diet; Feces; Humans; Male; Methylamines; Scintillation Counting; Tritium

1991
Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation.
    Life sciences, 2014, Nov-11, Volume: 117, Issue:2

    Topics: Animals; Betaine; Biosynthetic Pathways; Carbon Isotopes; Carnitine; Choline; Chromatography, High Pressure Liquid; Gastrointestinal Tract; Methylamines; Methylhydrazines; Microbiota; Rats; Rats, Wistar; Statistics, Nonparametric; Tandem Mass Spectrometry

2014
γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO.
    Cell metabolism, 2014, Nov-04, Volume: 20, Issue:5

    Topics: Animals; Atherosclerosis; Betaine; Carnitine; Female; Gastrointestinal Tract; Methylamines; Mice; Mice, Inbred C57BL; Microbiota

2014
Determination of trimethylamine-N-oxide in combination with L-carnitine and γ-butyrobetaine in human plasma by UPLC/MS/MS.
    Biomedical chromatography : BMC, 2015, Volume: 29, Issue:11

    Topics: Betaine; Carnitine; Chromatography, Liquid; Humans; Limit of Detection; Methylamines; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry

2015
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis.
    Atherosclerosis, 2016, Volume: 247

    Topics: Aged; Betaine; Biomarkers; Carnitine; Carotid Stenosis; Case-Control Studies; Cause of Death; Chromatography, High Pressure Liquid; Female; Humans; Kaplan-Meier Estimate; Lysine; Male; Methylamines; Middle Aged; Myocardial Infarction; Prognosis; Proportional Hazards Models; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke; Ultrasonography, Doppler, Color

2016
Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery.
    Metabolic syndrome and related disorders, 2016, Volume: 14, Issue:4

    Topics: Adult; Atherosclerosis; Bariatric Surgery; Betaine; Body Mass Index; Cardiovascular Diseases; Carnitine; Case-Control Studies; Choline; Chromatography, High Pressure Liquid; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Life Style; Male; Methylamines; Microbiota; Middle Aged; Obesity; Postoperative Period; Time Factors

2016
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2019, Volume: 38, Issue:10

    Topics: Acute Disease; Adult; Aged; Betaine; Carnitine; Coronary Artery Disease; Cyclosporine; Everolimus; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Methylamines; Microbiota; Middle Aged; Postoperative Complications

2019
Circulating gut microbiota metabolite trimethylamine N-oxide and oral contraceptive use in polycystic ovary syndrome.
    Clinical endocrinology, 2019, Volume: 91, Issue:6

    Topics: Adolescent; Adult; Betaine; Blood Glucose; Cardiovascular Diseases; Carnitine; Choline; Female; Gastrointestinal Microbiome; Humans; Methylamines; Obesity; Polycystic Ovary Syndrome; Prospective Studies; Risk Factors; Testosterone; Young Adult

2019
Changes in the concentrations of trimethylamine N-oxide (TMAO) and its precursors in patients with amyotrophic lateral sclerosis.
    Scientific reports, 2020, 09-16, Volume: 10, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Motor Neurons; Prognosis; Signal Transduction

2020
Association of gut-related metabolites with outcome in acute heart failure.
    American heart journal, 2021, Volume: 234

    Topics: Acetylcarnitine; Acute Disease; Aged; Aged, 80 and over; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Heart Failure; Hospital Mortality; Humans; Male; Methylamines; Natriuretic Peptide, Brain; Risk Factors; Statistics, Nonparametric

2021
Longitudinal Associations of Plasma TMAO and Related Metabolites with Cognitive Impairment and Dementia in Older Adults: The Cardiovascular Health Study.
    Journal of Alzheimer's disease : JAD, 2022, Volume: 89, Issue:4

    Topics: Animals; Betaine; Carnitine; Choline; Cognitive Dysfunction; Dementia; Medicare; Methylamines; United States

2022
Association of Systemic Trimethyllysine With Heart Failure With Preserved Ejection Fraction and Cardiovascular Events.
    The Journal of clinical endocrinology and metabolism, 2022, 11-25, Volume: 107, Issue:12

    Topics: Carnitine; Cross-Sectional Studies; Heart Failure; Humans; Prospective Studies; Stroke Volume

2022