trimethyloxamine has been researched along with choline in 203 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (3.94) | 18.7374 |
| 1990's | 4 (1.97) | 18.2507 |
| 2000's | 4 (1.97) | 29.6817 |
| 2010's | 88 (43.35) | 24.3611 |
| 2020's | 99 (48.77) | 2.80 |
| Authors | Studies |
|---|---|
| Gupta, KC; Miller, RL; Williams, JR | 1 |
| daCosta, KA; Hensey, S; Youssef, M; Zeisel, SH | 1 |
| Banjac, B; Drewes, LR; Kloiber, O | 1 |
| Charest, RP; Chenoweth, M; Dunn, A | 1 |
| Hansen, RC; Rothschild, JG | 1 |
| Charest, R; Dunn, A | 1 |
| Ellory, JC; Flanagan, GJ; O'Kelly, J; Rae, C; Winearls, CG | 1 |
| Andrews, MA; Nosek, TM | 1 |
| Mitchell, SC; Smith, RL; Zhang, AQ | 2 |
| Daikoku, T; El-Shourbagy, I; Hirata, T; Niizeki, N; Sakaguchi, M; Song, X | 1 |
| ALPERS, H; GEIGER, WB | 1 |
| AMIEL, C; ARDAILLOU, R; PELE, MF; RICHET, G | 1 |
| Antti, H; Beckonert, O; Bollard, ME; Ebbels, TM; Holmes, E; Keun, H; Lindon, JC; Nicholson, JK; Tang, H; Wang, Y | 1 |
| Arêas, JA; Lanfer-Marquez, UM; Podadera, P; Sipahi, AM | 1 |
| Bell, JD; Chung, YL; Hicks, J; Miller, FW; Passo, MH; Rennebohm, RM; Rider, LG; Scott, DL; Summers, RM; Zemel, LS | 1 |
| Blachier, F; Hao, F; He, Q; Kong, X; Li, P; Ren, P; Tang, H; Wu, G; Wu, Y; Yin, Y | 1 |
| Rader, DJ; Rak, K | 1 |
| Allayee, H; Bennett, BJ; Britt, EB; Chung, YM; DiDonato, JA; Dugar, B; Feldstein, AE; Fu, X; Hazen, SL; Klipfell, E; Koeth, R; Levison, BS; Lusis, AJ; Schauer, P; Smith, JD; Tang, WH; Wang, Z; Wu, Y | 1 |
| Allayee, H; Bennett, BJ; Crooke, R; de Aguiar Vallim, TQ; Edwards, PA; Graham, M; Gregory, J; Hazen, SL; Lee, R; Lusis, AJ; Meng, Y; Shih, DM; Wang, Z | 1 |
| Britt, EB; Brown, JM; Buffa, JA; Bushman, FD; Chen, J; DiDonato, JA; Fu, X; Hazen, SL; Koeth, RA; Krauss, RM; Levison, BS; Lewis, JD; Li, H; Li, L; Lusis, AJ; Org, E; Sheehy, BT; Smith, JD; Tang, WH; Wang, Z; Warrier, M; Wu, GD; Wu, Y | 1 |
| Britt, EB; Fu, X; Hazen, SL; Koeth, RA; Levison, BS; Tang, WH; Wang, Z; Wu, Y | 1 |
| Adams, MJ; Goto, S; Hancock, T; Hassell, K; Kirwan, GM; Niere, JO; Nugegoda, D | 1 |
| Stock, J | 1 |
| Miller, MJ | 1 |
| Britt, EB; Buffa, JA; Fan, Y; Fu, X; Hazen, SL; Koeth, RA; Levison, BS; Tang, WH; Wang, Z; Wu, Y | 1 |
| Allayee, H; Bennett, BJ; Hartiala, J; Hazen, SL; Lusis, AJ; McPherson, R; Roberts, R; Stewart, AF; Tang, WH; Wang, Z | 1 |
| Bennett, BJ; Blevins, T; Corbin, KD; da Costa, KA; Galanko, JA; Miller, CA; O'Connor, A; Zeisel, SH; Zhang, S; Zhao, X | 1 |
| Brown, JM; Hazen, SL | 1 |
| Guo, J; Li, J; Li, X; Liu, Y; Wang, L; Wu, T; Yang, Y; Yuan, F; Zhang, Q; Zheng, L | 1 |
| Hazen, SL; Tang, WH | 1 |
| Cirule, H; Dambrova, M; Grinberga, S; Gustina, D; Kuka, J; Liepins, J; Liepinsh, E; Loza, E; Makrecka-Kuka, M; Pugovics, O; Zharkova-Malkova, O | 1 |
| Bae, S; Bailey, LB; Beresford, SA; Brown, EC; Caudill, MA; Cheng, TY; Cushing-Haugen, KL; Green, R; Lane, DS; Malysheva, O; Miller, JW; Neuhouser, ML; Ulrich, CM; Xiao, L; Zheng, Y | 1 |
| Aakhus, S; Aukrust, P; Berge, RK; Bjørndal, B; Dahl, CP; Gregersen, I; Gude, E; Gullestad, L; Halvorsen, B; Hov, JR; Karlsen, TH; Svardal, A; Trøseid, M; Ueland, T; Yndestad, A | 1 |
| Borowski, AG; Hazen, SL; Klein, AL; Shrestha, K; Tang, WH; Troughton, RW; Wang, Z; Wu, Y | 1 |
| Bennett, BJ; Buffa, JA; DiDonato, JA; Gregory, JC; Hazen, SL; Levison, BS; Li, L; Lusis, AJ; Org, E; Wagner, MA; Wang, Z; Zhu, W | 1 |
| Abbara, S; Boccara, F; Capeau, J; Fitch, KV; Gauguier, D; Grinspoon, SK; Kadar, H; Knight, R; Lo, J; Srinivasa, S; Wong, K | 1 |
| Drosos, I; Kolios, G; Tavridou, A | 1 |
| Nolin, TD; Ocque, AJ; Stubbs, JR | 1 |
| Amador-Noguez, D; Rey, FE; Romano, KA; Vivas, EI | 1 |
| Berger, H; Caudill, MA; Croxford, R; El-Sohemy, A; Kim, YI; Lausman, AY; Ly, A; Malysheva, O; Masih, S; Nielsen, DE; O'Connor, DL; Plumptre, L; Sohn, KJ; Visentin, CE | 1 |
| Amaral, AC; Fouque, D; Mafra, D; Moraes, C | 1 |
| Boutagy, NE; Davy, BM; Davy, KP; Englund, TR; Hulver, MW; Neilson, AP; Osterberg, KL; Smithson, AT | 2 |
| Allenspach, M; Drexel, H; Mueller, DM; Muendlein, A; Othman, A; Saely, CH; von Eckardstein, A; Vonbank, A | 1 |
| Allayee, H; Bennett, BJ; Smallwood, T | 1 |
| Berge, RK; Bjørndal, B; Bohov, P; Bruheim, I; Nordrehaug, JE; Ramsvik, MS; Rostrup, E; Svardal, A | 1 |
| Allenspach, M; Linseisen, J; Müller, D; Rohrmann, S; von Eckardstein, A | 1 |
| Bhushan, S; Bradley, J; Hazen, SL; Lefer, DJ; Organ, CL; Otsuka, H; Polhemus, DJ; Tang, WH; Trivedi, R; Wang, Z; Wu, Y | 1 |
| Chen, XL; Chen, YM; Ling, WH; Liu, Y; Tan, XY; Wang, C; Wang, LJ; Zhang, HW; Zheng, RD; Zhou, RF; Zhu, HL | 1 |
| Barany, P; Bergman, P; Hällqvist, J; Heimbürger, O; Lindholm, B; Missailidis, C; Qureshi, AR; Stenvinkel, P | 1 |
| Awwad, HM; Geisel, J; Graeber, S; Herrmann, W; Obeid, R; Rabagny, Y | 1 |
| Hazen, SL; Lusis, AJ; Meng, Y; Qi, H; Seldin, MM; Shih, DM; Wang, Z; Zhu, W | 1 |
| Brown, JM; Buffa, JA; DiDonato, JA; Fu, X; Gregory, JC; Gupta, N; Hazen, SL; Li, L; Lusis, AJ; McIntyre, TM; Mehrabian, M; Org, E; Sartor, RB; Silverstein, RL; Tang, WHW; Wang, Z; Wu, Y; Zhu, W | 1 |
| Berge, RK; Hov, JR; Lappegård, KT; Nestvold, TK; Svardal, A; Thoresen, H; Trøseid, M | 1 |
| Hennig, B; Hoffman, JB; Morris, AJ; Perkins, JT; Petriello, MC; Sunkara, M; Wahlang, B | 1 |
| Ferrucci, L; Gonzalez-Freire, M; Maleta, KM; Manary, MJ; Moaddel, R; Ordiz, MI; Semba, RD; Trehan, I; Zhang, P | 1 |
| Tilg, H | 1 |
| Johnson, T; Kaaks, R; Katzke, V; Kühn, T; Müller, D; Rohrmann, S; Sookthai, D; von Eckardstein, A | 1 |
| Awwad, HM; Geisel, J; Graeber, S; Herrmann, W; Kirsch, SH; Obeid, R; Waldura, C | 1 |
| Chmurzynska, A; Malinowska, AM; Szwengiel, A | 1 |
| Fan, Y; Hazen, SL; Li, DS; Li, XS; Tang, WH; Wang, Z; Wu, Y | 1 |
| He, Y; Lu, JQ; Sheng, HF; Wang, S; Wu, S; Yin, J; Zheng, HM; Zhou, HW | 1 |
| Hazen, SL; Tang, WHW; Wang, Z; Zhu, W | 1 |
| Chen, MX; Lu, JQ; Nie, J; Wang, S; Xia, GH; Xu, KY; Yin, J; You, C; Zhen, X; Zhou, HW | 1 |
| Esteras, R; Fernandez-Prado, R; Gonzalez-Parra, E; Gracia-Iguacel, C; Ortiz, A; Perez-Gomez, MV; Sanchez-Niño, MD; Sanz, AB | 1 |
| Berge, RK; Haissman, JM; Haugaard, AK; Hov, JR; Nielsen, SD; Ostrowski, SR; Trøseid, M | 1 |
| Arós, F; Bulló, M; Clish, CB; Corella, D; Dennis, C; Estruch, R; Fiol, M; Fitó, M; Gómez-Gracia, E; Guasch-Ferré, M; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Toledo, E; Wang, DD | 1 |
| Bray, GA; Heianza, Y; Qi, L; Sacks, FM; Smith, SR; Sun, D | 1 |
| Ferreira, LA; Uversky, VN; Zaslavsky, BY | 1 |
| Blesso, CN; Caudill, MA; DiMarco, DM; Fernandez, ML; Lemos, BS; Malysheva, OV; Medina-Vera, I; Missimer, A; Murillo, AG; Norris, GH; Vergara-Jimenez, M | 1 |
| Cai, Y; Hong, W; Huang, M; Jin, J; Li, G; Xiao, C; Xu, C; Yu, W; Zhao, Y; Zhou, Z | 1 |
| Allayee, H; Buffa, JA; Cajka, T; DiDonato, JA; Fiehn, O; Gu, X; Han, Y; Hartiala, JA; Hazen, SL; Hurd, AG; Kerby, RL; Li, L; Li, XS; Lüscher, TF; Nemet, I; Obeid, S; Rey, FE; Roberts, AB; Romano, KA; Shahen, CJ; Skye, SM; Tang, WHW; Wagner, MA; Wang, Z; Wu, Y | 1 |
| Huet, B; Jialal, I; Lent-Schochet, D; McLaughlin, M; Silva, R | 1 |
| Bray, GA; DiDonato, JA; Heianza, Y; Li, X; Qi, L; Sacks, FM; Sun, D | 1 |
| Akrami, R; Bäckhed, F; Borén, J; Caesar, R; Fåk Hållenius, F; Lindskog Jonsson, A; Reinhardt, C | 1 |
| Anastos, K; Burk, RD; Clish, CB; Haberlen, SA; Hanna, DB; Hodis, HN; Hua, S; Kaplan, RC; Landay, AL; Lazar, JM; Margolick, JB; Post, WS; Qi, Q; Scott, JM; Sears, CL; Shah, SJ; Shan, Z | 1 |
| Dhar, I; Karlsson, T; Løland, KH; Nilsen, DW; Nordrehaug, JE; Nygård, O; Olset, H; Pedersen, ER; Schartum-Hansen, H; Schuster, PM; Seifert, R; Strand, E; Svenningsson, M; Svingen, GFT; Tell, GS; Ueland, PM; Zuo, H | 1 |
| Chmurzynska, A; Malinowska, AM; Mlodzik, MA; Nowacka-Woszuk, J; Radziejewska, A; Szwengiel, A | 1 |
| Qiu, L; Tao, X; Wei, H; Xiong, H; Yu, J | 1 |
| Barlik, M; Chmurzynska, A; Drews, K; Jagodziński, PP; Kurzawińska, G; Malinowska, AM; Radziejewska, A; Różycka, A; Seremak-Mrozikiewicz, A; Szwengiel, A | 1 |
| Rey, FE; Romano, KA | 1 |
| Al Rajabi, A; Curtis, JM; Field, CJ; Jacobs, RL; Ju, T; Leonard, KA; Mi, S; Nelson, R; Thiesen, A; van der Veen, JN; Willing, BP; Zia, Y | 1 |
| Cai, Y; Guo, H; He, M; Hou, FF; Huo, Y; Li, GF; Li, Y; Liu, S; Nie, J; Qin, X; Qiu, B; Wang, B; Wang, Y; Xie, L; Xu, X; Zhang, H; Zhao, BX; Zhu, F | 1 |
| DiDonato, JA; Fischbach, MA; Guo, CJ; Haag, B; Hazen, SL; Jia, X; Kirsop, J; Lang, JM; Lusis, AJ; Rey, FE; Romano, KA; Skye, SM; Tang, WHW; Wang, Z; Zhu, W | 1 |
| Freeman, LM; Karlin, ET; Rush, JE | 1 |
| Abidin, S; Bhandari, U; Gautam, A; Paudel, YN | 1 |
| Albright, J; Bennett, BJ; Biddinger, SB; Coffey, AR; Gertz, E; Gharaibeh, RZ; Hua, K; Kanke, M; Pitman, W; Pomp, D; Sethupathy, P; Smallwood, TL; Temel, RE | 1 |
| Gloor, GB; Joris, BR | 1 |
| Li, B; Li, C; Liu, J; Liu, Z; Yang, M; Zhang, Q; Zhao, P; Zhong, W; Zhong, Z | 1 |
| Bernieh, D; Cassambai, S; Heaney, LM; Israr, MZ; Salzano, A; Suzuki, T; Wong, M; Yazaki, Y | 1 |
| Cassano, PA; Caudill, MA; Taesuwan, S; Vermeylen, F | 1 |
| Angiletta, CJ; Baugh, ME; Davy, KP; Djuric, Z; Griffin, LE; Mitchell, CM; Neilson, AP | 1 |
| Crane, H; Deeks, SG; Drozd, D; Hsue, PY; Hunt, P; Ma, Y; Martin, J; Neilan, BD; Rahalkar, S; Scherzer, R; Sinha, A | 1 |
| Allayee, H; Brown, JM; Cantor, RM; Graham, M; Hazen, SL; Jia, X; Lee, R; Lusis, AJ; Meng, Y; Miikeda, A; Mueller, C; Schugar, RC; Shih, DM; Wang, Z; Zhu, W; Zieger, M | 1 |
| Abbott, KA; Alburikan, KA; Alkofide, HA; Garg, ML; Kalagi, NA; Stojanovski, E | 1 |
| Chen, L; Wu, J; Yang, H; Zhao, X | 1 |
| Chen, C; Chen, H; Cheng, Z; Mydland, LT; Overland, M; Peng, L; Pérez de Nanclares, M; Shurson, GC; Trudeau, MP; Urriola, PE; Yao, D | 1 |
| Bray, GA; Chen, Y; DiDonato, JA; Heianza, Y; LeBoff, MS; Li, X; Pei, X; Qi, L; Sacks, FM; Sun, D; Zhou, T | 1 |
| Cao, YF; Fang, ZZ; Hu, G; Huo, X; Leng, J; Li, J; Li, SN; Li, W; Liu, J; Ma, RCW; Shao, P; Yang, K; Yang, X | 1 |
| Nowiński, A; Ufnal, M | 1 |
| Aldana-Hernández, P; Curtis, JM; Field, CJ; Jacobs, RL; Leonard, KA; Zhao, YY | 1 |
| Acikgoz, A; Berge, RK; Bjørndal, B; Caliskan Guzelce, E; Eyupoglu, ND; Svardal, A; Uyanik, E; Yildiz, BO | 1 |
| Aguesse, A; Billon-Crossouard, S; Croyal, M; Ene, L; Guebre-Egziabher, F; Juillard, L; Krempf, M; Lemoine, S; Pelletier, CC; Soulage, CO | 1 |
| Cheng, I; Franke, AA; Fu, BC; Hullar, MAJ; Lampe, JW; Le Marchand, L; Lim, U; Madeleine, MM; Monroe, KR; Randolph, TW; Shepherd, JA; Wilkens, LR | 1 |
| Ren, D; Yang, C; Yang, X; Zhao, Y | 1 |
| Buffa, JA; DiDonato, JA; Gupta, N; Hazen, SL; Ho, KJ; Li, L; Roberts, AB; Sangwan, N; Skye, SM; Tang, WHW; Varga, J | 1 |
| Butler, LM; Gao, YT; Huang, JY; Jin, A; Koh, WP; Luu, HN; Midttun, Ø; Tan, Y; Ueland, PM; Ulvik, A; Wang, R; Yuan, JM | 1 |
| Chen, YC; Doma, H; Franks, AE; Fusco-Allison, G; Habtom, HT; Holmes, A; Koay, YC; Li, M; Luk, AWS; O'Sullivan, JF; Peter, K; Reimark, R; Simpson, SJ; Wali, JA; Yang, J; Zaldivia, MTK | 1 |
| Chen, T; Dai, X; Fei, H; Jiang, H; Lin, Q; Sun, Z; Wang, F; Wang, S; Wu, K; Yu, H; Yuan, Y | 1 |
| Meyer, KA | 1 |
| Goodchild, TT; Gupta, N; Hazen, SL; Lefer, DJ; Li, Z; Organ, CL; Polhemus, DJ; Sharp, TE; Tang, WHW | 1 |
| Bardagjy, AS; Houts, H; Randolph, JM; Sacchi, R; Sawrey-Kubicek, L; Steinberg, FM; Tang, X; Zhu, C; Zivkovic, AM | 1 |
| Chi, N; Jiang, XM; Wang, YM; Xue, CH; Yu, ZL; Zhang, LY; Zhang, TT | 1 |
| García-Cañas, V; Simó, C | 1 |
| Aardema, NDJ; Aguilar, SS; Bergeson, JR; Bunnell, ML; Caudill, MA; Cho, CE; Larson, DP; Lefevre, M; Malysheva, OV | 1 |
| Hazen, SL; Weeks, TL; Witkowski, M | 1 |
| Allison, J; Arboleya, S; Arias, JL; Arias, N; Gueimonde, M; Higarza, SG; Kaliszewska, A | 1 |
| Aguilar-Salinas, C; Campos-Pérez, F; Canizales-Quinteros, S; Gómez-Pérez, F; González-González, I; Grandini-Rosales, P; Hazen, SL; Hernández-Pando, R; Huertas-Vazquez, A; Hui, ST; Larrieta-Carrasco, E; León-Mimila, P; Li, XS; López-Contreras, B; Lusis, AJ; Macías-Kauffer, L; Morán-Ramos, S; Ocampo-Medina, E; Olivares-Arevalo, M; Shih, DM; Villamil-Ramírez, H; Villarreal-Molina, T; Wang, Z | 1 |
| Hwang, KT; Lee, K; Lim, T; Park, SY; Ryu, J | 1 |
| Besli, F; Erkus, ME; Genc Tapar, G; Gonel, A; Gungoren, F; Koyuncu, I; Tanriverdi, Z; Tascanov, MB | 1 |
| Chen, L; Chen, Y; Fan, D; Zhao, M; Zheng, L | 1 |
| Dai, Q; Guo, F; Liu, Y; Ouyang, D; Tan, Z; Zeng, X; Zhang, H | 1 |
| Emoto, T; Hirata, KI; Yamashita, T; Yoshida, N | 1 |
| Arnemo, JM; Bergman, P; Bieber, C; Ebert, T; Fröbert, O; Giroud, S; Göritz, F; Johnson, RJ; Kublickiene, K; Painer, J; Qureshi, AR; Redtenbacher, I; Shiels, PG; Stalder, G; Stenvinkel, P; Vetter, S; Zedrosser, A | 1 |
| Alonso-Gómez, A; Bulló, M; Clish, C; Corella, D; Estruch, R; Fiol, M; Fitó, M; Guasch-Ferré, M; Hernández-Alonso, P; Hu, FB; Li, J; Liang, L; Martínez-González, MA; Papandreou, C; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Santos-Lozano, JM; Serra-Majem, L; Toledo, E | 1 |
| Cao, W; Gao, M; Huang, T; Liu, Z; Yang, R; Zhuang, Z | 1 |
| Charugundla, S; Guo, F; Hazen, SL; Jia, X; Kaczor-Urbanowicz, KE; Lusis, AJ; Magyar, C; Miikeda, A; Nicholas, SB; Pellegrini, M; Shih, DM; Wang, Z; Zhang, W; Zhou, Z; Zuckerman, J | 1 |
| Bernieh, D; Cassambai, S; Heaney, LM; Israr, MZ; Jones, DJL; Ng, LL; Salzano, A; Suzuki, T; Yazaki, Y | 1 |
| Bu, X; Che, B; Ju, Z; Lu, Z; Qian, S; Wang, A; Xu, T; Zhang, J; Zhang, Y; Zheng, X; Zhong, C | 1 |
| Angius, A; Baragetti, A; Caredda, G; Caruso, D; Catapano, AL; Cibella, J; Consolandi, C; Dioguardi, CC; Giavarini, F; Grigore, L; Mattavelli, E; Norata, GD; Olmastroni, E; Peano, C; Pellegatta, F; Rotta, L; Severgnini, M | 1 |
| Coutinho-Wolino, KS; de F Cardozo, LFM; de Oliveira Leal, V; Mafra, D; Stockler-Pinto, MB | 1 |
| Chen, GY; Chepyala, D; Chiu, HH; Kuo, CH; Kuo, HC; Lu, WH | 1 |
| Fernandez, ML; Thomas, MS | 1 |
| Boekholdt, SM; Hazen, SL; Khaw, KT; Li, XS; Nieuwdorp, M; Tang, WHW; Wang, Z; Wareham, NJ; Wu, Y | 1 |
| Bahnson, J; Bihlmeyer, N; Chen, H; Ilkayeva, O; Kwee, LC; Laferrère, B; Muehlbauer, MJ; Newgard, CB; Purnell, JQ; Shah, SH; Wolfe, B; Xavier Pi-Sunyer, F | 1 |
| Cai, J; Fu, Y; Jia, L; Lei, A; Lin, R; Liu, C; Wang, L; Zhang, J | 1 |
| Duan, XF; Wang, CC; Wang, YM; Xue, CH; Zhang, TT | 1 |
| Ding, YJ; Jia, QJ; Li, YY; Lv, SC; Wang, YJ; Zhang, A; Zhang, JP; Zhang, WQ; Zhang, XN; Zhu, YP | 1 |
| Du, Y; Hong, B; Jiang, J; Jiang, Z; Li, X; Su, C; Wang, L; Yang, M; Yang, Y; Zhang, J; Zhang, X; Zhang, Y | 1 |
| Fu, X; Graham, B; Hazen, SL; Li, L; Li, XS; Neale, S; O'Laughlin, C; Peterson, K; Shelkay, S; Skye, SM; Tang, WHW; Wilcox, J; Zabell, A | 1 |
| Chan, A; Franke, A; Hu, FB; Huttenhower, C; Ivey, KL; Lee, KH; Li, J; Li, Y; Rimm, EB; Sun, Q; Wang, DD; Wilkinson, JE | 1 |
| Androjna, C; Brinson, K; Buffa, JA; DiDonato, AJ; DiDonato, JA; Fischbach, MA; Fu, X; Hajjar, AM; Hazen, SL; Li, L; Li, XS; Prakash, P; Rey, FE; Romano, KA; Sangwan, N; Tittle, AN; Trapp, BD; Zhu, W | 1 |
| Dong, E; Gao, J; Huang, M; Ji, L; Li, C; Ni, L; Shen, X; Wang, DW; Wang, Z; Wei, H; Yu, T; Zhang, Q; Zhao, C; Zhao, M; Zheng, L | 1 |
| Bergström, M; Fagerström, C; Hefni, ME; Lennqvist, T; Witthöft, CM | 1 |
| Chen, N; Chen, Y; Fan, L; He, X; Hou, Y; Li, J; Li, Y; Lin, X; Liu, J; Qi, H; Wang, M; Wu, C; Xiao, X; Yang, H; Zhang, H; Zhang, Y | 1 |
| Ao, L; Lai, W; Li, J; Liu, Z; Meng, X; Ren, H; Xian, G; Xiong, Z; Xu, D; Zeng, Q; Zhan, Q | 1 |
| Buffa, JA; DiDonato, JA; Friebel, J; Haghikia, A; Hazen, SL; Kirchhofer, D; Landmesser, U; Li, L; Li, XS; Lüscher, TF; Mach, F; Matter, CM; Räber, L; Rauch, U; Sangwan, N; Tang, WHW; Tizian, C; Wang, Z; Witkowski, M | 1 |
| Bäumler, AJ; Bennett, BJ; Byndloss, AJ; Byndloss, MX; Cevallos, SA; Foegeding, NJ; Gertz, E; Litvak, Y; Major, AS; Nguyen, H; Olsan, EE; Rathmell, JC; Shealy, NG; Shelton, CD; Thomas, JD; Tiffany, CR; Torres, TP; Yoo, W; Zieba, JK | 1 |
| Du, Y; Hong, B; Li, X; Su, C; Wang, L; Yang, Y; Zhang, X | 1 |
| Cao, Z; Guo, X; Liu, L; Wang, X; Xie, C; Yang, P; Zhang, Q | 1 |
| Lv, S; Shang, H; Wang, Y; Zhang, W | 1 |
| Al-Abbasi, FA; Alshehri, S; Bin-Jumah, MN; Ghoneim, MM; Gilani, SJ; Hosawi, S; Imam, SS; Kazmi, I; Nadeem, MS; Zeyadi, M | 1 |
| Bazeley, P; Ferrell, M; Garcia-Garcia, JC; Hazen, SL; Jia, X; Knight, R; Krauss, RM; Levison, BS; Li, XS; Lusis, AJ; Tang, WHW; Wang, Z | 1 |
| Kang, JW; Zivkovic, AM | 1 |
| Buawangpong, N; Chattipakorn, N; Chattipakorn, SC; Pinyopornpanish, K; Siri-Angkul, N | 1 |
| Allen, FM; Anderson, JT; Armstrong, AR; Banerjee, R; Brown, AL; Brown, JM; Buffa, JA; Burrows, A; Cook, K; Ferguson, D; Finney, C; Fung, KK; Garcia-Garcia, JC; Gliniak, CM; Goudarzi, M; Gromovsky, AD; Hazen, SL; Helsley, RN; Horak, A; Keshavarzian, A; Lusis, AJ; Mak, TD; Massey, W; McMillan, A; Mehrabian, M; Neumann, C; Orabi, D; Osborn, LJ; Sangwan, N; Schugar, RC; Swanson, G; Wang, Z; Willard, B | 1 |
| Dey, M; Dhakal, S; Moazzami, Z; Perry, C | 1 |
| Amrein, M; Bakula, A; Ceresa, B; Glarner, N; Haaf, P; Hazen, SL; Honegger, U; Koechlin, L; Leu, K; Li, XS; Mueller, C; Nestelberger, T; Puelacher, C; Schäfer, I; Strebel, I; Twerenbold, R; Walter, J; Wang, Z; Zellweger, M; Zimmermann, T | 1 |
| Dai, Y; Fu, P; Huang, L; Jiang, C; Li, C; Li, Y; Wang, J; Wang, TJ; Zhang, Z; Zhu, L | 1 |
| Hu, X; Jiang, YZ; Jin, X; Li, DQ; Liu, Q; Ma, D; Niu, C; Qian, M; Rong, X; Shao, ZM; Wang, H; Wen, Y; Wu, Y; Xiao, Y; Yan, Y; Yang, H; Zhao, C; Zhao, G; Zhou, Y | 1 |
| Chen, W; Guo, M; Li, X; Liu, Y; Shi, L; Wang, G; Wang, Q; Xu, M; Zhang, H; Zhao, J | 1 |
| Bernieh, D; Cassambai, S; Israr, MZ; Salzano, A; Suzuki, T; Wong, M; Yazaki, Y | 1 |
| Cantero, MA; Fernandes, R; Guedes, MRA; Lollo, PCB | 1 |
| Budoff, M; de Oliveira Otto, MC; DiDonato, JA; Fretts, AM; Hazen, SL; Jensen, P; Lai, H; Lee, Y; Lemaitre, RN; Mozaffarian, D; Psaty, BM; Siscovick, DS; Sitlani, CM; Sotoodehnia, N; Tang, WHW; Wang, M | 1 |
| Chen, M; Chen, P; Guo, Z; Liu, D; Luo, T; Ou, C | 1 |
| Harrison, EE; Waters, ML | 1 |
| Chen, CY; Chen, JW; Chou, RH; Huang, PH; Kuo, CS; Leu, HB; Lin, SJ; Lu, YW; Tsai, SH; Tsai, YL; Wang, SC | 1 |
| Cong, L; Fu, J; Han, P; Jiang, JD; Li, Y; Lin, Y; Ma, SR; Pan, LB; Peng, R; Tong, Q; Wang, Y; Yu, H; Yu, JB; Zhang, XF; Zhang, ZW; Zhao, ZX | 1 |
| Chen, B; Fu, Q; Wei, S; Xiong, X; Xu, X; Yang, S; Zhou, J | 1 |
| Anand, N; Chandana, KA; Chidambaram, SB; Kalyan, M; Kanna, PV; Mahalakshmi, AM; Pandi-Perumal, SR; Praveenraj, SS; Sakharkar, MK; Shasthara, P; Sonali, S; Tousif, HA; Vichitra, C; Yang, J | 1 |
| Ceglarek, U; Emonds, JJ; Gaudl, A; Meixensberger, J; Müller, D; Reinicke, M; Ringel, C; Von Eckardstein, A | 1 |
| Hong, Y; Ji, N; Luo, X; Ma, W; Nie, Z; Shan, J; Xue, J; Zhang, T; Zhang, Y; Zhou, S; Zhu, W | 1 |
| Chang, X; Dai, Y; Duan, Z; Guo, J; Qi, X; Tan, R; Wang, Z; Wu, C; Xu, S; Zhang, J; Zhang, Q; Zhou, Z | 1 |
| Cao, Y; Chang, X; Dai, Y; Guo, J; Liang, W; Lu, D; Lv, S; Qi, X; Wang, Z; Wu, C; Zhang, J; Zhang, L; Zhou, Z | 1 |
| Abe, M; Aoki, J; Fukuda, S; Ishii, C; Ishikawa, T; Kajimura, S; Kano, K; Katsuumi, G; Kubo, M; Kubota, Y; Minamino, T; Minokoshi, Y; Nakahara, K; Oda, K; Ohta, S; Okamoto, S; Okuda, S; Ozaki, K; Sakimura, K; Sasaoka, T; Shimada, A; Shimizu, I; Soga, T; Suda, M; Walsh, K; Yamamoto, H; Yanagisawa, S; Yoshida, Y; Yoshimura, N; Zuriaga, M | 1 |
| de Oliveira Otto, MC; Fretts, A; Hazen, SL; Lai, HTM; Lee, Y; Lemaitre, RN; Li, XS; Lopez, O; Mozaffarian, D; Nemet, I; Newman, AB; Siscovick, DS; Tang, WHW; Wang, M; Wang, Z | 1 |
| Feng, YQ; He, GD; Liu, XC; Lu, AS | 1 |
| Cheng, A; Jiang, X; Jin, A; Li, H; Li, K; Lin, J; Meng, X; Wang, Y; Xu, J; Xue, J; Zhao, M; Zheng, L | 1 |
| Gu, S; Liu, D; Ma, Z; Zhou, Z; Zuo, H | 1 |
| Arabpour, Z; Hasani, M; Khodabakhshi, A; Monfared, V; Vahid, F | 1 |
| France, TL; Frost, IR; Javaid, A; McFadden, JW; Myers, WA | 1 |
| Blanco, R; Daimiel, L; Dávalos, A; Díez-Ricote, L; Micó, V; Ordovás, JM; Ruiz-Valderrey, P; Tomé-Carneiro, J | 1 |
| Boon, MR; Fan, X; Li, Z; Liu, C; Rensen, PCN; Schönke, M; Shao, H; Song, Z; Wang, Y | 1 |
| Li, R; Liu, R; Wan, Z; Wang, G; Yu, Z; Zhang, Y; Zhang, Z | 1 |
| Arnold, CD; Beckner, AG; Bennett, BJ; Bragg, MG; Caswell, BL; DeBolt, MC; George, M; Maleta, KM; Oakes, LM; Prado, EL; Stewart, CP | 1 |
| Le, G; Li, B; Lu, M; Wang, X; Xie, Y; Xu, Y; Yang, Y | 1 |
| Ge, PX; Ji, JZ; Jiang, LP; Li, YF; Mi, QY; Tai, T; Xie, HG; Zhu, T | 1 |
| Tu, R; Xia, J | 1 |
| Barbieri, M; Bruzzese, F; De Biase, D; de Nigris, F; Luciano, A; Palma, G; Tacconi, E | 1 |
| Cai, XC; Han, HX; He, M; Kang, XX; Liu, X; Lv, EH; Tian, JQ; Wang, YT; Wen, PB; Xiao, L; Zhang, MY; Zhen, J; Zhou, Z | 1 |
| Bernhard, W; Böckmann, KA; Franz, AR; Minarski, M; Poets, CF; Shunova, A; Wiechers, C | 1 |
| Guo, X; He, S; He, Y; Li, L; Liang, W; Lin, X; Wang, J; Xiao, Y; Xiong, Q; Ying, C; Zhao, J; Zuo, X | 1 |
| Lazar, M; Olma, A; Streb, W | 1 |
| Chen, WX; Dong, J; Li, HX; Li, ZY; Mu, HN; Wang, SM; Yang, RY; Zhang, RR; Zhao, XH | 1 |
| Arnindita, JN; Dyah Lamara, A; Oktaviono, YH; Pasahari, D; Saputra, ME; Saputra, PBT; Suasti, NMA | 1 |
| Chadwick-Corbin, SA; Iglesias-Carres, L; Neilson, AP; Sweet, MG | 1 |
| Ament, Z; Bevers, MB; Bhave, VM; Couch, CA; Garcia Guarniz, AL; Irvin, MR; Kijpaisalratana, N; Kimberly, WT | 1 |
| Aly, M; Diaz-Rubio, ME; Johnson, EL; Le, HH; McFadden, JW; Perry, CA; Spence, LA; Tate, BN; Van Guilder, GP | 1 |
| Liang, Y; Liu, B; Liu, Z; Luo, Q; Xiong, C; Yang, B; Yang, Y; Zeng, Q; Zhao, Z | 1 |
| Banerjee, R; Brown, AL; Brown, JM; Burrows, AC; Cao, S; Hamoudi, MK; Hazen, SL; Horak, AJ; Jaramillo, TC; Kay, KE; Lathia, JD; Massey, WJ; Mrdjen, M; Osborn, LJ; Reizes, O; Silver, DJ; Wang, Z | 1 |
| Chen, ZY; He, Z; Kwek, E; Liu, J; Ma, KY; Zhu, H | 1 |
26 review(s) available for trimethyloxamine and choline
| Article | Year |
|---|---|
The contributory role of gut microbiota in cardiovascular disease.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Choline; Diet; Female; Food; Humans; Intestines; Male; Methylamines; Microbiota; Oxygenases; Phosphatidylcholines | 2014 |
New aspects on the metabolic role of intestinal microbiota in the development of atherosclerosis.
Topics: Animals; Atherosclerosis; Betaine; Carnitine; Choline; Humans; Intestinal Mucosa; Intestines; Methylamines; Microbiota; Phosphatidylcholines | 2015 |
Trimethylamine N-Oxide From Gut Microbiota in Chronic Kidney Disease Patients: Focus on Diet.
Topics: Animals; Cardiovascular Diseases; Carnitine; Choline; Diet, Protein-Restricted; Disease Models, Animal; Eggs; Gastrointestinal Microbiome; Humans; Methylamines; Randomized Controlled Trials as Topic; Red Meat; Renal Insufficiency, Chronic | 2015 |
Choline metabolites: gene by diet interactions.
Topics: Animals; Choline; Humans; Methylamines; Methylenetetrahydrofolate Reductase (NADPH2); Phosphatidylethanolamine N-Methyltransferase | 2016 |
Nutrients Turned into Toxins: Microbiota Modulation of Nutrient Properties in Chronic Kidney Disease.
Topics: Cardiovascular Diseases; Carnitine; Choline; Diet; Gastrointestinal Microbiome; Humans; Methylamines; Micronutrients; Oxalates; Phosphates; Phosphatidylcholines; Renal Insufficiency, Chronic; Tryptophan; Tyrosine | 2017 |
Is maternal microbial metabolism an early-life determinant of health?
Topics: Bacteria; Choline; Epigenesis, Genetic; Female; Gastrointestinal Microbiome; Humans; Maternal Exposure; Methylamines; Nutrients; Oxidants | 2018 |
Unaccounted risk of cardiovascular disease: the role of the microbiome in lipid metabolism.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Carnitine; Choline; Energy Metabolism; Fatty Acids, Volatile; Gastrointestinal Microbiome; Genomics; High-Throughput Nucleotide Sequencing; Humans; Lipid Metabolism; Metabolic Syndrome; Methylamines; Phosphatidylcholines; RNA, Ribosomal, 16S; T-Lymphocytes, Helper-Inducer; Triglycerides | 2019 |
Modulation of Circulating Trimethylamine N-Oxide Concentrations by Dietary Supplements and Pharmacological Agents: A Systematic Review.
Topics: Anti-Bacterial Agents; Antioxidants; Cardiovascular Diseases; Carnitine; Choline; Dietary Supplements; Gastrointestinal Microbiome; Humans; Methylamines; Prebiotics; Probiotics; Risk Factors | 2019 |
Dietary bioactive ingredients to modulate the gut microbiota-derived metabolite TMAO. New opportunities for functional food development.
Topics: Betaine; Biological Availability; Carnitine; Choline; Diet; Food Ingredients; Functional Food; Gastrointestinal Absorption; Gastrointestinal Microbiome; Gastrointestinal Tract; Heart Disease Risk Factors; Humans; Liver; Methylamines; Oxygenases | 2020 |
Gut Microbiota and Cardiovascular Disease.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Cardiovascular Diseases; Carnitine; Choline; Disease Models, Animal; Fatty Acids, Volatile; Fecal Microbiota Transplantation; Feces; Gastrointestinal Microbiome; Glutamine; Host Microbial Interactions; Humans; Methylamines; Mice; Mice, Inbred C57BL; Signal Transduction; Thrombosis; Vasculitis | 2020 |
The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases.
Topics: Animals; Biological Availability; Cardiovascular Diseases; Choline; Diet; Dysbiosis; Gastrointestinal Microbiome; Genotype; Humans; Inflammatory Bowel Diseases; Liver; Methylamines; Non-alcoholic Fatty Liver Disease; Renal Insufficiency, Chronic | 2020 |
Can diet modulate trimethylamine N-oxide (TMAO) production? What do we know so far?
Topics: Carnitine; Choline; Diet; Gastrointestinal Microbiome; Methylamines | 2021 |
Trimethylamine N-Oxide (TMAO), Diet and Cardiovascular Disease.
Topics: Cardiovascular Diseases; Choline; Diet; Humans; Methylamines | 2021 |
TMA/TMAO in Hypertension: Novel Horizons and Potential Therapies.
Topics: Animals; Carnitine; Choline; Gastrointestinal Microbiome; Glucose; Humans; Hypertension; Inflammation; Lipid Metabolism; Methylamines | 2021 |
Trimethylamine oxide: a potential target for heart failure therapy.
Topics: Cardiotonic Agents; Carnitine; Choline; Diuretics; Gastrointestinal Microbiome; Heart Failure; Humans; Methylamines | 2022 |
Pathobiological Relationship of Excessive Dietary Intake of Choline/L-Carnitine: A TMAO Precursor-Associated Aggravation in Heart Failure in Sarcopenic Patients.
Topics: Biodiversity; Biomarkers; Carnitine; Choline; Dietary Supplements; Disease Susceptibility; Dysbiosis; Gastrointestinal Microbiome; Heart Failure; Humans; Methylamines; Sarcopenia | 2021 |
Are eggs good again? A precision nutrition perspective on the effects of eggs on cardiovascular risk, taking into account plasma lipid profiles and TMAO.
Topics: Bacteria; Biological Variation, Population; Cardiovascular Diseases; Cholesterol; Choline; Diet; Eggs; Gastrointestinal Microbiome; Heart Disease Risk Factors; Humans; Methylamines; Phosphatidylcholines | 2022 |
The role of trimethylamine-N-Oxide in the development of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Choline; Methylamines; Oxides | 2022 |
The Gut Axis Involvement in Heart Failure: Focus on Trimethylamine N-oxide.
Topics: Choline; Gastrointestinal Microbiome; Heart Failure; Humans; Methylamines | 2022 |
Trimethylamine N-oxide reduction is related to probiotic strain specificity: A systematic review.
Topics: Animals; Cardiovascular Diseases; Choline; Gastrointestinal Microbiome; Humans; Methylamines; Probiotics | 2022 |
The Role of a Gut Microbial-Derived Metabolite, Trimethylamine N-Oxide (TMAO), in Neurological Disorders.
Topics: Betaine; Carnitine; Choline; Flavins; Gastrointestinal Microbiome; Humans; Inflammasomes; Lyases; Methylamines; Mixed Function Oxygenases; Nervous System Diseases; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein | 2022 |
Association between Levels of Trimethylamine N-Oxide and Cancer: A Systematic Review and Meta-Analysis.
Topics: Betaine; Choline; Female; Humans; Neoplasms; Risk Factors | 2023 |
Stroke and Vascular Cognitive Impairment: The Role of Intestinal Microbiota Metabolite TMAO.
Topics: Choline; Cognitive Dysfunction; Gastrointestinal Microbiome; Humans; Inflammation; Stroke; Thrombosis | 2024 |
Microbiota Effect on Trimethylamine N-Oxide Production: From Cancer to Fitness-A Practical Preventing Recommendation and Therapies.
Topics: Animals; Cardiovascular Diseases; Choline; Inflammation; Methylamines; Microbiota; Neoplasms | 2023 |
The gut microbial metabolite trimethylamine N-oxide and cardiovascular diseases.
Topics: Atherosclerosis; Cardiovascular Diseases; Choline; Gastrointestinal Microbiome; Humans; Methylamines | 2023 |
The roles of trimethylamine-N-oxide in atherosclerosis and its potential therapeutic aspect: A literature review.
Topics: Atherosclerosis; Choline; Endothelial Cells; Humans; Lyases; Oxides; Plaque, Atherosclerotic | 2023 |
23 trial(s) available for trimethyloxamine and choline
| Article | Year |
|---|---|
Dietary precursors of trimethylamine in man: a pilot study.
Topics: Adult; Choline; Diet; Humans; Male; Methylamines; Oxidants; Pilot Projects; Reference Values | 1999 |
Effect of egg ingestion on trimethylamine-N-oxide production in humans: a randomized, controlled, dose-response study.
Topics: Adult; Biomarkers; C-Reactive Protein; Choline; Cross-Over Studies; Double-Blind Method; Egg Yolk; Eggs; Female; Heart Diseases; Humans; Lipoproteins, LDL; Longitudinal Studies; Male; Methylamines; Middle Aged; North Carolina; Pilot Projects; Risk Factors; Up-Regulation | 2014 |
Probiotic supplementation and trimethylamine-N-oxide production following a high-fat diet.
Topics: Adolescent; Adult; Betaine; Carnitine; Choline; Diet, High-Fat; Dietary Supplements; Fasting; Humans; Male; Methylamines; Probiotics; Tandem Mass Spectrometry; Young Adult | 2015 |
Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults - a pilot study.
Topics: Adolescent; Adult; Animals; Atherosclerosis; Betaine; Carnitine; Choline; Chylomicrons; Cytokines; Dietary Fats, Unsaturated; Docosahexaenoic Acids; Eicosapentaenoic Acid; Erythrocytes; Euphausiacea; Fatty Acids, Unsaturated; Female; Humans; Lipoproteins, VLDL; Male; Methylamines; Particle Size; Pilot Projects; Triglycerides | 2015 |
Plasma trimethylamine-N-oxide following supplementation with vitamin D or D plus B vitamins.
Topics: Aged; Calcium; Choline; Female; Humans; Male; Methylamines; Middle Aged; Vitamin B Complex; Vitamin D | 2017 |
Gut Microbe-Generated Trimethylamine
Topics: Adult; Aspirin; Choline; Dietary Fats; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Thrombosis; Vegans | 2017 |
Plasma Metabolites From Choline Pathway and Risk of Cardiovascular Disease in the PREDIMED (Prevention With Mediterranean Diet) Study.
Topics: Aged; Aged, 80 and over; Betaine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Chi-Square Distribution; Choline; Chromatography, Liquid; Diet, Mediterranean; Female; Humans; Incidence; Male; Metabolomics; Methylamines; Middle Aged; Multivariate Analysis; Phospholipid Ethers; Phosphorylcholine; Proportional Hazards Models; Prospective Studies; Risk Factors; Spain; Tandem Mass Spectrometry; Time Factors; Treatment Outcome | 2017 |
Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial.
Topics: Adipose Tissue, White; Adiposity; Adult; Body Weight; Caloric Restriction; Carnitine; Choline; Diabetes Mellitus, Type 2; Diet, Reducing; Energy Metabolism; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Obesity; Treatment Outcome; Waist Circumference; Weight Loss | 2018 |
Compared to an Oatmeal Breakfast, Two Eggs/Day Increased Plasma Carotenoids and Choline without Increasing Trimethyl Amine N-Oxide Concentrations.
Topics: Adolescent; Adult; Antioxidants; Avena; Biomarkers; Breakfast; Cardiovascular Diseases; Carotenoids; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Choline; Cross-Over Studies; Diet; Eggs; Female; Gene Expression; Humans; Leukocytes, Mononuclear; Male; Methylamines; Risk Factors | 2018 |
Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial.
Topics: Adult; Amino Acids; Carnitine; Choline; Diet, Reducing; Female; Gastrointestinal Microbiome; Glucose; Humans; Insulin Resistance; Male; Massachusetts; Methylamines; Obesity; Overweight | 2019 |
Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential.
Topics: Adult; Animals; Bacterial Proteins; Choline; Clostridium; Fecal Microbiota Transplantation; Female; Gastrointestinal Microbiome; Humans; Lyases; Male; Methylamines; Mice; Mice, Inbred C57BL; Middle Aged; Platelet Activation; Thrombosis | 2018 |
A Mediterranean diet does not alter plasma trimethylamine N-oxide concentrations in healthy adults at risk for colon cancer.
Topics: Adult; Aged; Bacteria; Betaine; Choline; Colonic Neoplasms; Diet, Mediterranean; Fasting; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged | 2019 |
Circulating Gut Microbiota Metabolite Trimethylamine N-Oxide (TMAO) and Changes in Bone Density in Response to Weight Loss Diets: The POUNDS Lost Trial.
Topics: Absorptiometry, Photon; Adult; Bone Density; Carnitine; Choline; Diabetes Mellitus, Type 2; Diet, Reducing; Dietary Fats; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Nutritional Status; Obesity; Overweight; Weight Loss | 2019 |
Whole egg consumption increases plasma choline and betaine without affecting TMAO levels or gut microbiome in overweight postmenopausal women.
Topics: Aged; Bacteria; Betaine; Choline; Cross-Over Studies; Diet; Eggs; Feces; Female; Gastrointestinal Microbiome; Humans; Methylamines; Middle Aged; Obesity; Overweight; Postmenopause | 2020 |
Effect of Choline Forms and Gut Microbiota Composition on Trimethylamine-
Topics: Adult; Biomarkers; Cardiovascular Diseases; Choline; Cross-Over Studies; Diet; Dietary Supplements; Double-Blind Method; Female; Gastrointestinal Microbiome; Healthy Volunteers; Heart Disease Risk Factors; Humans; Male; Meals; Methylamines; Middle Aged; Phosphatidylcholines | 2020 |
Choline Pathway Nutrients and Metabolites and Cognitive Impairment After Acute Ischemic Stroke.
Topics: Aged; Antihypertensive Agents; Brain Ischemia; China; Choline; Cognition; Cognition Disorders; Cognitive Dysfunction; Female; Humans; Hypertension; Ischemic Stroke; Male; Methylamines; Middle Aged; Prognosis; Single-Blind Method; Stroke; Treatment Outcome | 2021 |
Metabolites and diabetes remission after weight loss.
Topics: Amino Acids, Branched-Chain; Bariatric Surgery; Betaine; Biomarkers; Choline; Diabetes Mellitus, Type 2; Female; Humans; Male; Mass Spectrometry; Methylamines; Middle Aged; Obesity; Obesity, Morbid; Remission Induction; Treatment Outcome; Tyrosine; Weight Loss | 2021 |
Dietary Choline Supplements, but Not Eggs, Raise Fasting TMAO Levels in Participants with Normal Renal Function: A Randomized Clinical Trial.
Topics: Adult; Choline; Diet; Drug Monitoring; Egg White; Egg Yolk; Female; Healthy Volunteers; Humans; Lipotropic Agents; Male; Methylamines; Phosphatidylcholines; Platelet Function Tests; Treatment Outcome | 2021 |
Fecal Microbiome Composition Does Not Predict Diet-Induced TMAO Production in Healthy Adults.
Topics: Adult; Bacteria; Choline; Cross-Over Studies; Diet; Feces; Gastrointestinal Microbiome; Humans; Lyases; Methylamines; Microbiota | 2021 |
Effects of Lean Pork on Microbiota and Microbial-Metabolite Trimethylamine-N-Oxide: A Randomized Controlled Non-Inferiority Feeding Trial Based on the Dietary Guidelines for Americans.
Topics: Animals; Choline; Gastrointestinal Microbiome; Humans; Methylamines; Microbiota; Nutrition Policy; Oxides; Pork Meat; Poultry; Red Meat; Swine | 2022 |
Different choline supplement metabolism in adults using deuterium labelling.
Topics: Adult; Betaine; Choline; Cross-Over Studies; Deuterium; Fatty Acids; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Phosphatidylcholines; Phosphorylcholine; Prospective Studies | 2023 |
The Effect of Inulin-Type Fructans on Plasma Trimethylamine N-Oxide Levels in Peritoneal Dialysis Patients: A Randomized Crossover Trial.
Topics: Choline; Cross-Over Studies; Fructans; Humans; Inulin; Methylamines; Peritoneal Dialysis | 2023 |
Changes in Choline Metabolites and Ceramides in Response to a DASH-Style Diet in Older Adults.
Topics: Aged; Ceramides; Choline; Dietary Approaches To Stop Hypertension; Humans; Lecithins; Meat; Sphingomyelins | 2023 |
154 other study(ies) available for trimethyloxamine and choline
| Article | Year |
|---|---|
Isolation of trimethyl amine oxide and other bases from the hydroid Tubularia larynx.
Topics: Animals; Choline; Dimethylamines; Hydra; Methylamines | 1978 |
Conversion of dietary choline to trimethylamine and dimethylamine in rats: dose-response relationship.
Topics: Animals; Choline; Diet; Dimethylamines; Dose-Response Relationship, Drug; Male; Methylamines; Rats; Rats, Inbred Strains | 1989 |
Protection against acute hyperammonemia: the role of quaternary amines.
Topics: Acetates; Ammonia; Animals; Betaine; Carnitine; Choline; Glutamates; Glutamic Acid; Glutamine; Male; Methylamines; Mice | 1988 |
Metabolism of trimethylamines in kelp bass (Paralabrax clathratus) and marine and freshwater pink salmon (Oncorhynchus gorbuscha).
Topics: Animals; Bass; Betaine; Choline; Dimethylamines; Liver; Methylamines; Muscles; Perciformes; Radioactive Tracers; Salmon; Water-Electrolyte Balance | 1988 |
Fish odor syndrome: trimethylaminuria with milk as chief dietary factor.
Topics: Animals; Cattle; Child; Choline; Humans; Infant; Liver; Male; Methylamines; Milk; Syndrome | 1985 |
Chromatographic separation of choline, trimethylamine, trimethylamine oxide, and betaine from tissues of marine fish.
Topics: Animals; Betaine; Carnitine; Choline; Chromatography, Ion Exchange; Fishes; Liver; Methylamines; Muscles; Tissue Extracts | 1984 |
Human erythrocyte choline uptake in uraemia: the role of intracellular substrate and an investigation into the effects of haemodialysis.
Topics: Choline; Dimethylamines; Erythrocytes; Female; Humans; Ion Transport; Magnetic Resonance Spectroscopy; Male; Methylamines; Renal Dialysis; Uremia | 1996 |
Ion-specific protein destabilization of the contractile proteins of cardiac muscle fibers.
Topics: Animals; Calcium; Cations; Choline; Contractile Proteins; Drug Stability; Electrochemistry; Methylamines; Myocardial Contraction; Myocardium; Osmolar Concentration; Oxidants; Papillary Muscles; Potassium; Potassium Chloride; Rabbits; Sodium Lactate; Sucrose | 1998 |
Dimethylamine formation in the rat from various related amine precursors.
Topics: Administration, Oral; Animals; Choline; Diet; Dimethylamines; Ethylamines; Male; Methylamines; Oxidants; Propanols; Rats; Rats, Wistar | 1998 |
Mechanism of biosynthesis of trimethylamine oxide from choline in the teleost tilapia, Oreochromis niloticus, under freshwater conditions.
Topics: Animals; Carbon Radioisotopes; Choline; Chromatography, Gas; Diet; Fresh Water; Intestinal Mucosa; Methylamines; Oxygenases; Tilapia | 2002 |
PROPERTIES OF AN ACETYLATED DERIVATIVE OF TRIMETHYLAMINE OXIDE.
Topics: Acetylcholine; Alcohols; Alkaloids; Ammonium Compounds; Animals; Annelida; Anura; Atropine; Carbachol; Choline; Female; Guinea Pigs; Hallucinogens; Heart; Hexamethonium Compounds; Humans; Ileum; Insecta; Leeches; Methylamines; Mollusca; Muscle, Smooth; Muscles; Pharmacology; Quaternary Ammonium Compounds; Research; Tripelennamine; Urethane; Uterus; Yohimbine | 1964 |
[ACIDIFICATION OF URINE AFTER INGESTION OF CHOLINE CHLORIDE. ROLE OF TRIMETHYLAMINE OXIDE AS AN ACCEPTOR OF H+ IONS IN URINE].
Topics: Amines; Body Fluids; Chlorides; Choline; Eating; Homeostasis; Hydrogen-Ion Concentration; Methylamines; Urine | 1965 |
Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues.
Topics: Alanine; Animals; Chemical and Drug Induced Liver Injury; Choline; Glucose; Glycogen; Hydrazines; Lipids; Liver; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Methylamines; Rats; Rats, Sprague-Dawley; Taurine; Toxins, Biological | 2003 |
Diagnosis of suspected trimethylaminuria by NMR spectroscopy.
Topics: Adult; Amines; Animals; Choline; Diet; Dogfish; Humans; Magnetic Resonance Spectroscopy; Male; Metabolism, Inborn Errors; Methylamines; Odorants; Oxidation-Reduction; Reference Standards; Solutions | 2005 |
Muscle metabolites, detected in urine by proton spectroscopy, correlate with disease damage in juvenile idiopathic inflammatory myopathies.
Topics: Adolescent; Betaine; Biomarkers; Child; Child, Preschool; Choline; Creatine; Female; Glycine; Humans; Magnetic Resonance Spectroscopy; Male; Methylamines; Muscles; Myositis | 2005 |
Comparison of serum metabolite compositions between obese and lean growing pigs using an NMR-based metabonomic approach.
Topics: Animals; Blood Glucose; Body Composition; Choline; Glucagon; Insulin; Lipid Metabolism; Lipoproteins, HDL; Lipoproteins, VLDL; Magnetic Resonance Spectroscopy; Metabolomics; Methylamines; Multivariate Analysis; Obesity; Swine | 2012 |
Cardiovascular disease: the diet-microbe morbid union.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Choline; Diet; Dietary Fats; Gastrointestinal Tract; Humans; Liver; Metabolomics; Methylamines; Mice; Oxygenases; Phosphatidylcholines; Probiotics; Risk Assessment | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; Diet; Dietary Fats; Female; Gastrointestinal Tract; Gene Expression Regulation; Germ-Free Life; Humans; Liver; Macrophages; Metabolomics; Methylamines; Mice; Mice, Inbred C57BL; Oxygenases; Phenotype; Phosphatidylcholines; Receptors, Scavenger; Risk Assessment | 2011 |
Gut microbes may affect heart disease risk. But studies in rodents suggesting a link may not play out in people.
Topics: Animals; Choline; Dietary Supplements; Humans; Intestines; Lecithins; Methylamines; Mice; Prebiotics; Probiotics | 2012 |
Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation.
Topics: Androgens; Animals; Atherosclerosis; Base Sequence; Bile Acids and Salts; Choline; Diet; Down-Regulation; Female; Gene Silencing; HEK293 Cells; Humans; Male; Methylamines; Mice; Mice, Knockout; Oxygenases; Polymorphism, Single Nucleotide; Receptors, Cytoplasmic and Nuclear; Sex Factors | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; Macrophages; Mass Spectrometry; Meat; Metagenome; Methylamines; Mice; Mice, Knockout; RNA; Time Factors | 2013 |
Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk.
Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Betaine; Cardiovascular Diseases; Choline; Female; Humans; Intestinal Mucosa; Intestines; Kaplan-Meier Estimate; Male; Metagenome; Methylamines; Middle Aged; Phosphatidylcholines; Prospective Studies; Risk Factors | 2013 |
Nuclear magnetic resonance metabonomic profiling using tO2PLS.
Topics: Animals; Biomarkers; Choline; Estradiol; Magnetic Resonance Spectroscopy; Metabolome; Metabolomics; Methylamines; Models, Biological; Perciformes; Software | 2013 |
Gut microbiota: an environmental risk factor for cardiovascular disease.
Topics: Cardiovascular Diseases; Choline; Diet, Mediterranean; Environment; Environmental Pollutants; Humans; Metagenome; Methylamines; Risk Factors | 2013 |
Risk factors for cardiovascular disease: a cautionary tale of diet-microbiome interactions.
Topics: Cardiovascular Diseases; Carnitine; Choline; Diet; Gastrointestinal Tract; Humans; Methylamines; Microbiota; Risk Factors | 2013 |
Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide.
Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Female; Humans; Intestinal Mucosa; Kaplan-Meier Estimate; Male; Methylamines; Mice; Microbiota; Middle Aged; Prognosis; Prospective Studies; Risk Assessment; Risk Factors | 2014 |
Comparative genome-wide association studies in mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of choline and L-carnitine.
Topics: Aged; Animals; Carnitine; Cation Transport Proteins; Choline; Chromosomes, Human, Pair 1; Female; Genome-Wide Association Study; Humans; Male; Methylamines; Mice; Middle Aged; Multigene Family; Oxygenases; Polymorphism, Single Nucleotide | 2014 |
Eggs as a dietary source for gut microbial production of trimethylamine-N-oxide.
Topics: Choline; Eggs; Female; Heart Diseases; Humans; Male; Methylamines; Up-Regulation | 2014 |
Serum metabonomic analysis of apoE(-/-) mice reveals progression axes for atherosclerosis based on NMR spectroscopy.
Topics: Animals; Atherosclerosis; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Choline; Diet, High-Fat; Disease Models, Animal; Disease Progression; Glycine; Inositol; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methylamines; Mice; Mice, Knockout; Multivariate Analysis; Taurine | 2014 |
Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation.
Topics: Animals; Betaine; Biosynthetic Pathways; Carbon Isotopes; Carnitine; Choline; Chromatography, High Pressure Liquid; Gastrointestinal Tract; Methylamines; Methylhydrazines; Microbiota; Rats; Rats, Wistar; Statistics, Nonparametric; Tandem Mass Spectrometry | 2014 |
Plasma choline metabolites and colorectal cancer risk in the Women's Health Initiative Observational Study.
Topics: Aged; Betaine; Choline; Colorectal Neoplasms; Female; Humans; Methylamines; Middle Aged; Risk Factors; Women's Health | 2014 |
Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure.
Topics: Aged; Betaine; Biomarkers; Choline; Chronic Disease; Female; Heart Failure; Humans; Intestinal Mucosa; Intestines; Lipotropic Agents; Male; Methylamines; Microbiota; Middle Aged; Oxidants; Predictive Value of Tests; Prognosis; Prospective Studies; Risk Assessment; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Survival Analysis | 2015 |
Intestinal microbiota-dependent phosphatidylcholine metabolites, diastolic dysfunction, and adverse clinical outcomes in chronic systolic heart failure.
Topics: Adult; Aged; Betaine; Biomarkers; Blood Pressure; Choline; Chronic Disease; Cohort Studies; Female; Heart Failure, Systolic; Humans; Intestinal Mucosa; Male; Methylamines; Microbiota; Middle Aged; Phosphatidylcholines; Prospective Studies; Risk Factors; Treatment Outcome | 2015 |
Transmission of atherosclerosis susceptibility with gut microbial transplantation.
Topics: Animals; Aorta; Atherosclerosis; Cecum; Choline; Diet; Disease Susceptibility; Female; Gastrointestinal Tract; Host-Pathogen Interactions; Humans; Male; Methylamines; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred Strains; Mice, Knockout; Mice, Transgenic; Microbiota; Species Specificity | 2015 |
Plaque burden in HIV-infected patients is associated with serum intestinal microbiota-generated trimethylamine.
Topics: Choline; Coronary Artery Disease; Dysbiosis; Female; HIV Infections; Humans; Intestinal Diseases; Male; Methylamines; Middle Aged; Plaque, Atherosclerotic; Prognosis; Risk Assessment; Risk Factors | 2015 |
Development and validation of a simple UHPLC-MS/MS method for the simultaneous determination of trimethylamine N-oxide, choline, and betaine in human plasma and urine.
Topics: Betaine; Calibration; Choline; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Kidney Diseases; Mass Spectrometry; Methylamines; Pilot Projects; Quality Control; Reference Standards; Reproducibility of Results | 2015 |
Intestinal microbiota composition modulates choline bioavailability from diet and accumulation of the proatherogenic metabolite trimethylamine-N-oxide.
Topics: Animals; Choline; Diet; Gastrointestinal Microbiome; Germ-Free Life; Humans; Methylamines; Mice; Microbiota; Molecular Sequence Data; Sequence Analysis, DNA | 2015 |
Maternal Choline Status, but Not Fetal Genotype, Influences Cord Plasma Choline Metabolite Concentrations.
Topics: Adolescent; Adult; Betaine; Canada; Choline; Female; Fetal Blood; Fetus; Genotype; Healthy Volunteers; Humans; Maternal Nutritional Physiological Phenomena; Methylamines; Middle Aged; Polymorphism, Single Nucleotide; Pregnancy; Prospective Studies; Sarcosine; Surveys and Questionnaires; Young Adult | 2015 |
Short-term high-fat diet increases postprandial trimethylamine-N-oxide in humans.
Topics: Adolescent; Adult; Betaine; Carnitine; Choline; Diet, Atherogenic; Diet, High-Fat; Fasting; Gastrointestinal Microbiome; Humans; Male; Methylamines; Oxidants; Postprandial Period; Young Adult | 2015 |
Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control.
Topics: Aged; Betaine; Biomarkers; Blood Glucose; Choline; Chromatography, Liquid; Coronary Angiography; Coronary Disease; Diabetes Mellitus; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Metabolic Syndrome; Methylamines; Middle Aged; Predictive Value of Tests; Prognosis; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2015 |
Plasma Concentrations of Trimethylamine-N-oxide Are Directly Associated with Dairy Food Consumption and Low-Grade Inflammation in a German Adult Population.
Topics: Adult; Animals; Betaine; C-Reactive Protein; Choline; Dairy Products; Diet; Diet Surveys; Feeding Behavior; Female; Germany; Humans; Inflammation; Interleukin-6; Male; Methylamines; Middle Aged; Milk; Receptors, Tumor Necrosis Factor, Type I; Tumor Necrosis Factor-alpha | 2016 |
Choline Diet and Its Gut Microbe-Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload-Induced Heart Failure.
Topics: Animals; Bacteria; Cardiomegaly; Choline; Diet; Disease Models, Animal; Disease Progression; Fibrosis; Heart Failure; Intestines; Male; Methylamines; Mice, Inbred C57BL; Myocardium; Pulmonary Edema; Risk Factors; Severity of Illness Index; Stroke Volume; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left | 2016 |
Associations of gut-flora-dependent metabolite trimethylamine-N-oxide, betaine and choline with non-alcoholic fatty liver disease in adults.
Topics: Adolescent; Adult; Aged; Betaine; Biomarkers; Case-Control Studies; Choline; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Non-alcoholic Fatty Liver Disease; Severity of Illness Index; Tandem Mass Spectrometry; Ultrasonography | 2016 |
Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease.
Topics: Adult; Aged; Betaine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Choline; Female; Fibrinogen; Glomerular Filtration Rate; Humans; Inflammation; Interleukin-6; Kidney Transplantation; Longitudinal Studies; Male; Methylamines; Middle Aged; Multivariate Analysis; Prognosis; Renal Dialysis; Renal Insufficiency, Chronic; Severity of Illness Index; Survival Analysis | 2016 |
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Gastrointestinal Microbiome; Humans; Lipoproteins, HDL; Male; Methylamines; Methylation; Middle Aged; Phosphatidylcholines; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors | 2016 |
Trimethylamine N-Oxide Promotes Vascular Inflammation Through Signaling of Mitogen-Activated Protein Kinase and Nuclear Factor-κB.
Topics: Animals; Aorta; Aortitis; Atherosclerosis; Cell Adhesion; Cells, Cultured; Choline; Coculture Techniques; Disease Models, Animal; Endothelial Cells; Enzyme Activation; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Humans; Leukocytes; Methylamines; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Phenotype; Receptors, LDL; Signal Transduction | 2016 |
Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.
Topics: Animals; Blood Platelets; Calcium; Carotid Artery Injuries; Cecum; Chlorides; Choline; Diet; Female; Ferric Compounds; Gastrointestinal Microbiome; Germ-Free Life; Humans; Methylamines; Mice; Mice, Inbred C57BL; Thrombosis | 2016 |
Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery.
Topics: Adult; Atherosclerosis; Bariatric Surgery; Betaine; Body Mass Index; Cardiovascular Diseases; Carnitine; Case-Control Studies; Choline; Chromatography, High Pressure Liquid; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Life Style; Male; Methylamines; Microbiota; Middle Aged; Obesity; Postoperative Period; Time Factors | 2016 |
Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors.
Topics: Administration, Oral; Animals; Atherosclerosis; Biomarkers; Choline; Deuterium; Dietary Fats; Environmental Pollutants; Enzyme Induction; Food-Drug Interactions; Liver; Male; Methylamines; Mice, Inbred C57BL; Oxygenases; Phosphatidylcholines; Polychlorinated Biphenyls; Random Allocation; Up-Regulation | 2016 |
The association of serum choline with linear growth failure in young children from rural Malawi.
Topics: Betaine; Child, Preschool; Choline; Chromatography, Liquid; Cross-Sectional Studies; Diet; Female; Growth; Growth Disorders; Humans; Infant; Malawi; Male; Mass Spectrometry; Methylamines; Nutritional Status; Risk Factors; Rural Population | 2016 |
A Gut Feeling about Thrombosis.
Topics: Animals; Choline; Gastrointestinal Microbiome; Humans; Methylamines; Mice; Plasmalogens; Risk Factors; Thrombosis | 2016 |
Intra-individual variation of plasma trimethylamine-N-oxide (TMAO), betaine and choline over 1 year.
Topics: Aged; Aged, 80 and over; Betaine; Choline; Chromatography, Liquid; Female; Humans; Male; Mass Spectrometry; Methylamines; Middle Aged; Time Factors | 2017 |
Dietary, anthropometric, and biochemical factors influencing plasma choline, carnitine, trimethylamine, and trimethylamine-N-oxide concentrations.
Topics: Aged; Body Size; Carnitine; Choline; Diet; Female; Humans; Methylamines; Middle Aged | 2017 |
Increased Trimethylamine N-Oxide Portends High Mortality Risk Independent of Glycemic Control in Patients with Type 2 Diabetes Mellitus.
Topics: Aged; Betaine; Blood Glucose; Choline; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Methylamines; Middle Aged; Prospective Studies; Risk Factors; Survival Rate | 2017 |
[A machine learning model using gut microbiome data for predicting changes of trimethylamine-N-oxide in healthy volunteers after choline consumption].
Topics: Algorithms; Choline; Eggs; Gastrointestinal Microbiome; Healthy Volunteers; Humans; Machine Learning; Methylamines; Oxides; RNA, Ribosomal, 16S | 2017 |
Impaired renal function and dysbiosis of gut microbiota contribute to increased trimethylamine-N-oxide in chronic kidney disease patients.
Topics: Adult; Aged; Animals; Betaine; Carnitine; Case-Control Studies; Choline; Clostridiaceae; Dysbiosis; Fecal Microbiota Transplantation; Female; Gammaproteobacteria; Gastrointestinal Microbiome; High-Throughput Nucleotide Sequencing; Humans; Kidney Function Tests; Male; Methylamines; Mice; Mice, Inbred C57BL; Middle Aged; Renal Insufficiency, Chronic | 2017 |
Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection.
Topics: Adult; Betaine; Biomarkers; Blood Platelets; Cardiovascular Diseases; Carnitine; Choline; Cross-Sectional Studies; Female; HIV Infections; Humans; Lipopolysaccharide Receptors; Male; Methylamines; Microbiota; Middle Aged; Monocytes; Myocardial Infarction; Platelet Aggregation; Risk Factors | 2017 |
Phase equilibria, solvent properties, and protein partitioning in aqueous polyethylene glycol-600-trimethylamine N-oxide and polyethylene glycol-600-choline chloride two-phase systems.
Topics: Chemistry Techniques, Analytical; Choline; Dextrans; Ethers; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Methylamines; Polyethylene Glycols; Polymers; Propylene Glycols; Proteins; Solvents; Static Electricity; Water | 2018 |
Simultaneous determination of trimethylamine N-oxide, choline, betaine by UPLC-MS/MS in human plasma: An application in acute stroke patients.
Topics: Aged; Betaine; Choline; Chromatography, High Pressure Liquid; Female; Humans; Male; Methylamines; Plasma; Reproducibility of Results; Sensitivity and Specificity; Stroke; Tandem Mass Spectrometry | 2018 |
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk.
Topics: Aged; Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Cholesterol; Choline; Disease Models, Animal; Feces; Female; Gastrointestinal Microbiome; Genome-Wide Association Study; Humans; Lysine; Male; Metabolomics; Methylamines; Mice; Mice, Inbred C57BL; Middle Aged; Nutrients; Risk Factors; Thrombosis | 2018 |
Changes to trimethylamine-N-oxide and its precursors in nascent metabolic syndrome.
Topics: Adult; Aged; Biomarkers; Carnitine; Choline; Female; Humans; Inflammation; Male; Metabolic Syndrome; Methylamines; Middle Aged; Young Adult | 2018 |
Impact of Gut Microbiota and Diet on the Development of Atherosclerosis in Apoe
Topics: Animal Feed; Animals; Aortic Diseases; Atherosclerosis; Bacteria; Cholesterol; Choline; Diet, Western; Dietary Supplements; Disease Models, Animal; Gastrointestinal Microbiome; Intestines; Male; Methylamines; Mice, Inbred C57BL; Mice, Knockout, ApoE; Ribotyping | 2018 |
Gut Microbial-Related Choline Metabolite Trimethylamine-N-Oxide Is Associated With Progression of Carotid Artery Atherosclerosis in HIV Infection.
Topics: Atherosclerosis; Biomarkers; Carotid Arteries; Carotid Artery Diseases; Choline; Female; Gastrointestinal Microbiome; HIV Infections; Humans; Inflammation; Male; Methylamines; Middle Aged; Monocytes; Plaque, Atherosclerotic | 2018 |
Increased plasma trimethylamine-N-oxide is associated with incident atrial fibrillation.
Topics: Aged; Atrial Fibrillation; Choline; Female; Follow-Up Studies; Humans; Incidence; Male; Methylamines; Middle Aged; Norway; Prognosis; Risk Factors | 2018 |
Caloric restriction can affect one-carbon metabolism during pregnancy in the rat: A transgenerational model.
Topics: Animals; Betaine; Caloric Restriction; Carbon; Choline; DNA Methylation; Female; Gene Expression; Homocysteine; Hydrolases; Liver; Male; Methylamines; Models, Biological; Pregnancy; Pregnancy, Animal; Rats, Wistar; S-Adenosylmethionine | 2018 |
Lactobacillus plantarum ZDY04 exhibits a strain-specific property of lowering TMAO via the modulation of gut microbiota in mice.
Topics: Animals; Atherosclerosis; Bacteria; Choline; Female; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Lactobacillus plantarum; Liver; Male; Methylamines; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Probiotics; Species Specificity | 2018 |
PEMT rs12325817 and PCYT1A rs7639752 polymorphisms are associated with betaine but not choline concentrations in pregnant women.
Topics: Adolescent; Adult; Alleles; Betaine; Birth Weight; Carnitine; Choline; Choline-Phosphate Cytidylyltransferase; Diet; Female; Folic Acid; Genotype; Homozygote; Humans; Infant, Newborn; Methylamines; Nutritional Status; Phosphatidylethanolamine N-Methyltransferase; Poland; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications; Young Adult | 2018 |
Hepatic Expression of PEMT, but Not Dietary Choline Supplementation, Reverses the Protection against Atherosclerosis in Pemt-/-/Ldlr-/- Mice.
Topics: Animals; Aorta; Atherosclerosis; Cholesterol; Cholesterol, Dietary; Choline; Diet, Western; Dietary Supplements; Humans; Liver; Male; Methylamines; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Receptors, LDL | 2018 |
Serum Trimethylamine N-Oxide Concentration Is Positively Associated With First Stroke in Hypertensive Patients.
Topics: Aged; Carnitine; Case-Control Studies; China; Choline; Female; Folic Acid; Gastrointestinal Microbiome; Humans; Hypertension; Male; Methylamines; Middle Aged; Odds Ratio; Stroke | 2018 |
A pilot study investigating circulating trimethylamine N-oxide and its precursors in dogs with degenerative mitral valve disease with or without congestive heart failure.
Topics: Animals; Carnitine; Case-Control Studies; Choline; Cross-Sectional Studies; Dog Diseases; Dogs; Echocardiography; Female; Heart Failure; Male; Methylamines; Mitral Valve Insufficiency; Pilot Projects | 2019 |
Guggulsterone, a farnesoid X receptor antagonist lowers plasma trimethylamine-
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; Cardiotonic Agents; Choline; Clostridium; Diet; Escherichia; Hypolipidemic Agents; Kidney; Lipid Peroxidation; Liver; Methylamines; Myocardium; Pregnenediones; Rats, Wistar; Receptors, Cytoplasmic and Nuclear | 2019 |
microRNA-146a-5p association with the cardiometabolic disease risk factor TMAO.
Topics: Animals; Atherosclerosis; Chlorocebus aethiops; Choline; Cohort Studies; Collaborative Cross Mice; Diet, Atherogenic; Diet, High-Fat; Disease Models, Animal; Female; Gene Knockout Techniques; Hypercholesterolemia; Liver; Methylamines; Mice; Mice, Knockout; MicroRNAs; NF-kappa B; Receptor, Insulin; Risk Factors; RNA-Seq | 2019 |
Targeted metabolomic analysis of plasma metabolites in patients with coronary heart disease in southern China.
Topics: Aged; Angina, Stable; Angina, Unstable; Biomarkers; Carnitine; China; Choline; Chromatography, Liquid; Creatinine; Female; Humans; Male; Metabolomics; Methylamines; Middle Aged; Myocardial Infarction; Prospective Studies; Reproducibility of Results; ROC Curve; Tandem Mass Spectrometry | 2019 |
Impact of acute choline loading on circulating trimethylamine N-oxide levels.
Topics: Biomarkers; Cardiovascular Diseases; Choline; Diet; Healthy Volunteers; Humans; Lipotropic Agents; Methylamines | 2019 |
Relation of choline intake with blood pressure in the National Health and Nutrition Examination Survey 2007-2010.
Topics: Adult; Aged; Blood Pressure; Choline; Cross-Sectional Studies; Female; Humans; Hypertension; Male; Methylamines; Middle Aged; Nutrition Surveys; Sex Factors; United States; Young Adult | 2019 |
Carnitine Is Associated With Atherosclerotic Risk and Myocardial Infarction in HIV -Infected Adults.
Topics: Adult; Antiretroviral Therapy, Highly Active; Atherosclerosis; Betaine; Carnitine; Carotid Artery Diseases; Carotid Intima-Media Thickness; Choline; Female; Gastrointestinal Microbiome; HIV Infections; Humans; Male; Methylamines; Middle Aged; Myocardial Infarction; Plaque, Atherosclerotic; Sustained Virologic Response; United States | 2019 |
Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report.
Topics: Animals; Atherosclerosis; Choline; Disease Models, Animal; Lipid Metabolism; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxygenases; Polymerase Chain Reaction; Random Allocation; Reference Values; Thrombosis | 2019 |
Effect of vacuum impregnated fish gelatin and grape seed extract on metabolite profiles of tilapia (Oreochromis niloticus) fillets during storage.
Topics: Animals; Choline; Cichlids; Fish Products; Food Storage; Gelatin; Grape Seed Extract; Histidine; Magnetic Resonance Spectroscopy; Methylamines; Multivariate Analysis; Vacuum | 2019 |
Identification of Sinapine-Derived Choline from a Rapeseed Diet as a Source of Serum Trimethylamine
Topics: Animal Feed; Animals; Biological Availability; Brassica rapa; Choline; Diet; Gastrointestinal Microbiome; Hydrolysis; Liver; Male; Methylamines; Sus scrofa | 2019 |
Trimethylamine N-Oxide Metabolites in Early Pregnancy and Risk of Gestational Diabetes: A Nested Case-Control Study.
Topics: Adult; Betaine; Blood Glucose; Carnitine; Case-Control Studies; China; Choline; Diabetes, Gestational; Female; Humans; Methylamines; Pregnancy; Prenatal Care; Risk Factors | 2019 |
Is increased plasma TMAO a compensatory response to hydrostatic and osmotic stress in cardiovascular diseases?
Topics: Animals; Cardiovascular Diseases; Cardiovascular System; Carnitine; Choline; Diet; Humans; Hydrostatic Pressure; Kidney; Liver; Methylamines; Mice; Models, Theoretical; Osmotic Pressure; Rats; Risk Factors | 2019 |
Dietary Choline or Trimethylamine N-oxide Supplementation Does Not Influence Atherosclerosis Development in Ldlr-/- and Apoe-/- Male Mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Choline; Dietary Supplements; Male; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, LDL | 2020 |
Circulating gut microbiota metabolite trimethylamine N-oxide and oral contraceptive use in polycystic ovary syndrome.
Topics: Adolescent; Adult; Betaine; Blood Glucose; Cardiovascular Diseases; Carnitine; Choline; Female; Gastrointestinal Microbiome; Humans; Methylamines; Obesity; Polycystic Ovary Syndrome; Prospective Studies; Risk Factors; Testosterone; Young Adult | 2019 |
Elevation of Trimethylamine-N-Oxide in Chronic Kidney Disease: Contribution of Decreased Glomerular Filtration Rate.
Topics: Adult; Betaine; Choline; Creatinine; Female; Gastrointestinal Microbiome; Glomerular Filtration Rate; Humans; Male; Metabolic Clearance Rate; Methylamines; Middle Aged; Prospective Studies; Renal Dialysis; Renal Insufficiency, Chronic | 2019 |
Associations of plasma trimethylamine N-oxide, choline, carnitine, and betaine with inflammatory and cardiometabolic risk biomarkers and the fecal microbiome in the Multiethnic Cohort Adiposity Phenotype Study.
Topics: Adiposity; Aged; Bacteria; Betaine; Biomarkers; Cardiovascular Diseases; Carnitine; Choline; Cohort Studies; Cross-Sectional Studies; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged | 2020 |
Protective Effect of Saponins-Enriched Fraction of Gynostemma pentaphyllum against High Choline-Induced Vascular Endothelial Dysfunction and Hepatic Damage in Mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Chemical and Drug Induced Liver Injury; Cholesterol, LDL; Choline; Endothelium, Vascular; Glutathione Peroxidase; Gynostemma; Liver; Malondialdehyde; Methylamines; Mice; Nitric Oxide Synthase Type III; Oxidative Stress; Plant Extracts; Saponins; Thromboxane A2; Triglycerides | 2020 |
Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease.
Topics: Animals; Bacteria; Bacterial Proteins; Choline; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Gastrointestinal Microbiome; Kidney; Lyases; Male; Methylamines; Mice, Inbred C57BL; Renal Insufficiency, Chronic | 2020 |
A prospective evaluation of serum methionine-related metabolites in relation to pancreatic cancer risk in two prospective cohort studies.
Topics: Betaine; Case-Control Studies; Choline; Female; Humans; Male; Methionine; Methylamines; Middle Aged; Odds Ratio; Pancreatic Neoplasms; Prospective Studies; Risk Factors | 2020 |
Plasma levels of trimethylamine-N-oxide can be increased with 'healthy' and 'unhealthy' diets and do not correlate with the extent of atherosclerosis but with plaque instability.
Topics: Animal Feed; Animals; Atherosclerosis; Bacteria; Biomarkers; Carotid Artery Diseases; Choline; Coronary Artery Disease; Diet, Healthy; Dietary Fiber; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Heart Disease Risk Factors; Humans; Male; Methylamines; Mice, Inbred C57BL; Mice, Knockout, ApoE; Plaque, Atherosclerotic; Receptors, LDL; Rupture, Spontaneous; Vascular Calcification | 2021 |
The gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice.
Topics: Animals; Choline; Cytokines; Dietary Fats; Gastrointestinal Microbiome; Graft vs Host Disease; Inflammasomes; Macrophages; Methylamines; Mice; Mice, Inbred BALB C; Mice, Knockout; T-Lymphocytes, Helper-Inducer | 2020 |
Population studies of TMAO and its precursors may help elucidate mechanisms.
Topics: Adiposity; Betaine; Biomarkers; Cardiovascular Diseases; Carnitine; Choline; Humans; Methylamines; Microbiota; Phenotype | 2020 |
Nonlethal Inhibition of Gut Microbial Trimethylamine N-oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure.
Topics: Animals; Bacteria; Bacterial Proteins; Choline; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Fibrosis; Gastrointestinal Microbiome; Heart Failure; Intestines; Lyases; Male; Methylamines; Mice, Inbred C57BL; Myocardium; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Effects of dietary choline, betaine, and L-carnitine on the generation of trimethylamine-N-oxide in healthy mice.
Topics: Animals; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Intestines; Male; Methylamines; Mice; Mice, Inbred BALB C | 2020 |
Trimethylamine N-oxide levels are associated with NASH in obese subjects with type 2 diabetes.
Topics: Adult; Betaine; Bile Acids and Salts; Biomarkers; Biopsy; Choline; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Liver; Male; Methylamines; Mexican Americans; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity | 2021 |
Protective Effects of Black Raspberry (
Topics: Animals; Anthocyanins; Cecum; Choline; Cyclooxygenase 2; Diet, High-Fat; Dietary Supplements; Eating; Female; Hepatitis; Hypercholesterolemia; Interleukin-1beta; Liver; Methylamines; NF-kappa B; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Rubus | 2020 |
Comparisons of microbiota-generated metabolites in patients with young and elderly acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adult; Age Factors; Aged; Biomarkers; Choline; Female; Humans; Male; Methylamines; Microbiota; Middle Aged; Risk Factors | 2020 |
Changes in the concentrations of trimethylamine N-oxide (TMAO) and its precursors in patients with amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Motor Neurons; Prognosis; Signal Transduction | 2020 |
Renal function is associated with plasma trimethylamine-N-oxide, choline, L-carnitine and betaine: a pilot study.
Topics: Betaine; Biomarkers; Carnitine; Choline; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Methylamines; Middle Aged; Pilot Projects; Renal Insufficiency, Chronic; Retrospective Studies | 2021 |
Unraveling the Effects of Trimethylamine N-Oxide on Stroke: "The lower, the better?"
Topics: Betaine; Carnitine; Cholesterol; Choline; Diet Therapy; Gastrointestinal Microbiome; Humans; Ischemic Stroke; Lipotropic Agents; Liver; Methylamines; Oxidants; Risk Factors | 2021 |
Insights in the regulation of trimetylamine N-oxide production using a comparative biomimetic approach suggest a metabolic switch in hibernating bears.
Topics: Adult; Aged; Aged, 80 and over; Animals; Betaine; Biomimetics; Cardiovascular Diseases; Choline; Female; Gastrointestinal Microbiome; Hibernation; Humans; Lions; Male; Methylamines; Middle Aged; Myoxidae; Prospective Studies; Renal Insufficiency, Chronic; Sus scrofa; Tigers; Ursidae | 2020 |
Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study.
Topics: Aged; Atrial Fibrillation; Betaine; Carnitine; Case-Control Studies; Choline; Female; Heart Failure; Humans; Male; Methylamines; Prospective Studies; Risk Factors; Sarcosine | 2021 |
Causal relationships between gut metabolites and Alzheimer's disease: a bidirectional Mendelian randomization study.
Topics: Alzheimer Disease; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Genetic Predisposition to Disease; Humans; Male; Mendelian Randomization Analysis; Methylamines; Negative Results; Risk | 2021 |
Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice.
Topics: Adenine; Albuminuria; Animals; Cardiomegaly; Choline; Disease Models, Animal; Female; Fibroblast Growth Factor-23; Fibrosis; Gastrointestinal Microbiome; Kidney; Methylamines; Mice; Renal Insufficiency, Chronic | 2021 |
Association of gut-related metabolites with outcome in acute heart failure.
Topics: Acetylcarnitine; Acute Disease; Aged; Aged, 80 and over; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Heart Failure; Hospital Mortality; Humans; Male; Methylamines; Natriuretic Peptide, Brain; Risk Factors; Statistics, Nonparametric | 2021 |
Gut Microbiota Functional Dysbiosis Relates to Individual Diet in Subclinical Carotid Atherosclerosis.
Topics: Adult; Aged; Aged, 80 and over; Bacteria; Carnitine; Carotid Artery Diseases; Choline; Diet; Dysbiosis; Escherichia coli; Faecalibacterium prausnitzii; Feces; Feeding Behavior; Female; Gastrointestinal Microbiome; High-Throughput Nucleotide Sequencing; Humans; Life Style; Male; Metagenomics; Methylamines; Middle Aged; Palmitates | 2021 |
Using matrix-induced ion suppression combined with LC-MS/MS for quantification of trimethylamine-N-oxide, choline, carnitine and acetylcarnitine in dried blood spot samples.
Topics: Acetylcarnitine; Carnitine; Choline; Chromatography, Liquid; Dried Blood Spot Testing; Humans; Methylamines; Oxides; Reproducibility of Results; Tandem Mass Spectrometry | 2021 |
Plasma trimethylamine N-oxide (TMAO) levels predict future risk of coronary artery disease in apparently healthy individuals in the EPIC-Norfolk prospective population study.
Topics: Aged; Case-Control Studies; Choline; Coronary Artery Disease; Correlation of Data; Female; Gastrointestinal Microbiome; Healthy Volunteers; Humans; Male; Methylamines; Middle Aged; Predictive Value of Tests; Prognosis; Risk Factors; United Kingdom | 2021 |
Gut microbial metabolite TMAO portends prognosis in acute ischemic stroke.
Topics: Aged; Biomarkers; China; Choline; Cohort Studies; Female; Gastrointestinal Microbiome; Humans; Ischemic Stroke; Male; Methylamines; Middle Aged; Prognosis; Prospective Studies | 2021 |
Trimethylamine
Topics: Betaine; Choline; Methylamines; Molecular Structure | 2021 |
Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome.
Topics: Animals; Atherosclerosis; Berberine; Choline; Diet; Disease Models, Animal; Disease Susceptibility; Dysbiosis; Gastrointestinal Microbiome; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE | 2021 |
Interplay between diet and gut microbiome, and circulating concentrations of trimethylamine N-oxide: findings from a longitudinal cohort of US men.
Topics: Cardiovascular Diseases; Choline; Diet; Gastrointestinal Microbiome; Humans; Male; Methylamines | 2022 |
Gut microbes impact stroke severity via the trimethylamine N-oxide pathway.
Topics: Animals; Bacteria; Choline; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Mice; Mice, Inbred C57BL; Oxides; Severity of Illness Index; Stroke | 2021 |
FMO3-TMAO axis modulates the clinical outcome in chronic heart-failure patients with reduced ejection fraction: evidence from an Asian population.
Topics: Carnitine; Choline; Chronic Disease; Heart Failure; Humans; Methylamines; Oxygenases; Prospective Studies | 2022 |
Simultaneous quantification of trimethylamine N-oxide, trimethylamine, choline, betaine, creatinine, and propionyl-, acetyl-, and L-carnitine in clinical and food samples using HILIC-LC-MS.
Topics: Betaine; Carnitine; Choline; Chromatography, Liquid; Creatinine; Female; Food Analysis; Humans; Limit of Detection; Male; Methylamines; Middle Aged; Tandem Mass Spectrometry | 2021 |
The Choline Metabolite TMAO Inhibits NETosis and Promotes Placental Development in GDM of Humans and Mice.
Topics: Adult; Animals; Case-Control Studies; Cells, Cultured; Choline; Diabetes, Gestational; Extracellular Traps; Female; Fetal Development; Humans; Infant, Newborn; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout; Placentation; Pregnancy; Protein-Arginine Deiminase Type 4; Young Adult | 2021 |
Trimethylamine N-oxide induces osteogenic responses in human aortic valve interstitial cells in vitro and aggravates aortic valve lesions in mice.
Topics: Animals; Aortic Valve; Aortic Valve Stenosis; Calcinosis; Cells, Cultured; Choline; Humans; Methylamines; Mice; NF-kappa B; Osteogenesis | 2022 |
Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis.
Topics: Animals; Choline; Endothelial Cells; Humans; Lyases; Methylamines; Mice; Thromboplastin; Thrombosis | 2022 |
High-fat diet-induced colonocyte dysfunction escalates microbiota-derived trimethylamine
Topics: Animals; Cell Hypoxia; Choline; Colon; Diet, High-Fat; Energy Metabolism; Epithelial Cells; Escherichia coli; Feces; Gastrointestinal Microbiome; Inflammation; Intestinal Mucosa; Male; Methylamines; Mice; Mice, Inbred C57BL; Mitochondria; Nitrates; Obesity; Oxygen Consumption | 2021 |
Metformin alleviates choline diet-induced TMAO elevation in C57BL/6J mice by influencing gut-microbiota composition and functionality.
Topics: Akkermansia; Animals; Atherosclerosis; Bifidobacterium; Choline; Diabetes Mellitus, Type 2; Diet; Dysbiosis; Female; Gastrointestinal Microbiome; Humans; Metformin; Methylamines; Mice; Mice, Inbred C57BL; RNA, Ribosomal, 16S | 2021 |
Unraveling the metabolic pathway of choline-TMA-TMAO: Effects of gypenosides and implications for the therapy of TMAO related diseases.
Topics: Animals; Brain; Choline; Feces; Female; Gastrointestinal Microbiome; Gynostemma; Lipid Metabolism; Methylamines; Mice, Inbred BALB C; Microsomes, Liver; Oxygenases; Plant Extracts; RNA, Ribosomal, 16S | 2021 |
Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms.
Topics: Animals; Choline; Circadian Rhythm; Diet, High-Fat; Enzyme Inhibitors; Gastrointestinal Microbiome; Leptin; Lyases; Male; Methylamines; Mice; Mice, Inbred C57BL; Obesity | 2022 |
Gut microbiota-dependent metabolite trimethylamine N-oxide (TMAO) and cardiovascular risk in patients with suspected functionally relevant coronary artery disease (fCAD).
Topics: Betaine; Cardiovascular Diseases; Carnitine; Choline; Coronary Artery Disease; Gastrointestinal Microbiome; Heart Disease Risk Factors; Humans; Methylamines; Risk Factors | 2022 |
Diet-Induced High Serum Levels of Trimethylamine-N-oxide Enhance the Cellular Inflammatory Response without Exacerbating Acute Intracerebral Hemorrhage Injury in Mice.
Topics: Acute Disease; Animals; Astrocytes; Brain Injuries; Cerebral Hemorrhage; Choline; Diet; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Interleukin-1beta; Male; Methylamines; Mice; Mice, Inbred C57BL; Microglia; Neutrophil Infiltration; Neutrophils; p38 Mitogen-Activated Protein Kinases; Signal Transduction | 2022 |
The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer.
Topics: Choline; Humans; Methylamines; Microbiota; Triple Negative Breast Neoplasms; Tumor Microenvironment | 2022 |
Topics: Animals; Bifidobacterium breve; Bifidobacterium longum; Choline; Gastrointestinal Microbiome; Methylamines; Mice; Mice, Inbred C57BL | 2022 |
Association of Trimethylamine N-Oxide and Metabolites With Mortality in Older Adults.
Topics: Aged; Betaine; Cardiovascular Diseases; Carnitine; Choline; Cohort Studies; Female; Humans; Male; Methylamines; Prospective Studies | 2022 |
Deficiency of proline/serine-rich coiled-coil protein 1 (PSRC1) accelerates trimethylamine N-oxide-induced atherosclerosis in ApoE
Topics: Animals; Atherosclerosis; Cholesterol; Cholesterol, LDL; Choline; Inflammation; Leukocytes, Mononuclear; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Phosphoproteins; Sulfotransferases | 2022 |
Application of an Imprint-and-Report Sensor Array for Detection of the Dietary Metabolite Trimethylamine N-Oxide and Its Precursors in Complex Mixtures.
Topics: Betaine; Choline; Complex Mixtures; Humans; Methylamines | 2022 |
Inhibition of Trimethylamine N-Oxide Attenuates Neointimal Formation Through Reduction of Inflammasome and Oxidative Stress in a Mouse Model of Carotid Artery Ligation.
Topics: Animals; Atherosclerosis; Carotid Arteries; Choline; Disease Models, Animal; Humans; Inflammasomes; Mice; NF-kappa B; Oxidative Stress; Vascular Remodeling | 2023 |
Berberine treats atherosclerosis via a vitamine-like effect down-regulating Choline-TMA-TMAO production pathway in gut microbiota.
Topics: Animals; Atherosclerosis; Choline; Cricetinae; Gastrointestinal Microbiome; Methylamines; Vitamins | 2022 |
The associations between TMAO-related metabolites and blood lipids and the potential impact of rosuvastatin therapy.
Topics: Atherosclerosis; Betaine; Carnitine; Cholesterol, LDL; Choline; Humans; Lipids; Methylamines; Rosuvastatin Calcium; Tandem Mass Spectrometry | 2022 |
Influence of Trimethylamine
Topics: Choline; Chromatography, Liquid; Lipids; Methylamines; Platelet Activation; Reproducibility of Results; Tandem Mass Spectrometry | 2022 |
Gut-Flora-Dependent Metabolite Trimethylamine-N-Oxide Promotes Atherosclerosis-Associated Inflammation Responses by Indirect ROS Stimulation and Signaling Involving AMPK and SIRT1.
Topics: AMP-Activated Protein Kinases; Animals; Atherosclerosis; Choline; Gastrointestinal Microbiome; Inflammation; Methylamines; Mice; Oxides; Reactive Oxygen Species; Sirtuin 1 | 2022 |
Associations of Diet with Urinary Trimethylamine-N-Oxide (TMAO) and Its Precursors among Free-Living 10-Year-Old Children: Data from SMBCS.
Topics: Animals; Choline; Diet; Humans; Meat; Methylamines; Oxides | 2022 |
Multiple mediation effects on association between prenatal triclosan exposure and birth outcomes.
Topics: Acetylcarnitine; Bayes Theorem; Betaine; Choline; Cohort Studies; Estradiol; Female; Humans; Leptin; Maternal Exposure; Methylamines; Oxides; Pregnancy; Testosterone; Thyroid Hormones; Thyroxine; Triclosan | 2022 |
Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism.
Topics: Adipocytes, Brown; Adipose Tissue, Brown; Animals; Choline; Heart Failure; Methylamines; Mice; Myocardial Infarction; Thermogenesis | 2022 |
Longitudinal Associations of Plasma TMAO and Related Metabolites with Cognitive Impairment and Dementia in Older Adults: The Cardiovascular Health Study.
Topics: Animals; Betaine; Carnitine; Choline; Cognitive Dysfunction; Dementia; Medicare; Methylamines; United States | 2022 |
Association of Choline Intake with Blood Pressure and Effects of Its Microbiota-Dependent Metabolite Trimethylamine-N-Oxide on Hypertension.
Topics: Animals; Blood Pressure; Choline; Hypertension; Methylamines; Microbiota; Nutrition Surveys; Oxides; Rats; Rats, Inbred SHR; Water | 2022 |
Residual Risk of Trimethylamine-N-Oxide and Choline for Stroke Recurrence in Patients With Intensive Secondary Therapy.
Topics: C-Reactive Protein; Choline; Humans; Inflammation; Lipids; Methylamines; Oxides; Platelet Aggregation Inhibitors; Risk Factors; Stroke | 2022 |
Associations of plasma TMAO and its precursors with stroke risk in the general population: A nested case-control study.
Topics: Betaine; Carnitine; Case-Control Studies; Choline; Humans; Stroke | 2023 |
Changes in plasma and milk choline metabolite concentrations in response to the provision of various rumen-protected choline prototypes in lactating dairy cows.
Topics: Animal Feed; Animals; Betaine; Cattle; Choline; Diet; Dietary Supplements; Female; Lactation; Milk; Rumen | 2022 |
TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis.
Topics: Animals; Atherosclerosis; Betaine; Cardiovascular Diseases; Carnitine; Choline; Humans; Inflammation; Methylamines; Mice; MicroRNAs | 2022 |
Choline and butyrate beneficially modulate the gut microbiome without affecting atherosclerosis in APOE*3-Leiden.CETP mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Butyrates; Cholesterol Ester Transfer Proteins; Choline; Female; Gastrointestinal Microbiome; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE | 2022 |
Trimethylamine N-oxide aggravated cognitive impairment from APP/PS1 mice and protective roles of voluntary exercise.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Betaine; Brain-Derived Neurotrophic Factor; Cathepsin B; Choline; Cognitive Dysfunction; Exercise; Mice; Motor Activity; Occludin | 2023 |
The association between plasma choline, growth and neurodevelopment among Malawian children aged 6-15 months enroled in an egg intervention trial.
Topics: Betaine; Child; Choline; Cross-Sectional Studies; Humans; Infant; Methylamines | 2023 |
Dietary Methionine Restriction Alleviates Choline-Induced Tri-Methylamine-N-Oxide (TMAO) Elevation by Manipulating Gut Microbiota in Mice.
Topics: Animals; Bacteria; Choline; Gastrointestinal Microbiome; Humans; Methionine; Methylamines; Mice; Racemethionine | 2023 |
Choline and trimethylamine N-oxide impair metabolic activation of and platelet response to clopidogrel through activation of the NOX/ROS/Nrf2/CES1 pathway.
Topics: Acetylcysteine; Activation, Metabolic; Animals; Choline; Clopidogrel; Male; Mice; NF-E2-Related Factor 2; Reactive Oxygen Species | 2023 |
TRIMETHYLAMINE OXIDE - FACTOR IN THE DEVELOPMENT OF ATHEROSCLEROSIS AND A POTENTIAL TARGET FOR DIETARY AND PHARMACOLOGICAL INTERVENTIONS.
Topics: Atherosclerosis; Carnitine; Choline; Humans; Methylamines | 2023 |
Choline and trimethylamine N-oxide supplementation in normal chow diet and western diet promotes the development of atherosclerosis in Apoe -/- mice through different mechanisms.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Cardiovascular Diseases; Choline; Diet, Western; Dietary Supplements; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE | 2023 |
Dietary phenolics and their microbial metabolites are poor inhibitors of trimethylamine oxidation to trimethylamine N-oxide by hepatic flavin monooxygenase 3.
Topics: Animals; Chlorogenic Acid; Choline; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenols; Rats | 2023 |
Trimethylamine N-Oxide and White Matter Hyperintensity Volume Among Patients With Acute Ischemic Stroke.
Topics: Aged; Betaine; Carnitine; Cerebral Small Vessel Diseases; Choline; Cross-Sectional Studies; Female; Humans; Ischemic Stroke; Male; Stroke; Stroke, Lacunar; White Matter | 2023 |
Circulating choline levels are associated with prognoses in patients with pulmonary hypertension: a cohort study.
Topics: Choline; Cohort Studies; Humans; Hypertension, Pulmonary; Inpatients; Prognosis; Pulmonary Arterial Hypertension | 2023 |
Metaorganismal choline metabolism shapes olfactory perception.
Topics: Animals; Bacteria; Choline; Female; Methylamines; Mice; Mice, Inbred C57BL; Olfactory Perception | 2023 |
Mangiferin alleviates trimethylamine-
Topics: Animals; Atherosclerosis; Cholesterol; Choline; Female; Gastrointestinal Microbiome; Methylamines; Mice; Oxides; Xanthones | 2023 |