trimethyloxamine and 4-phenylbutyric acid

trimethyloxamine has been researched along with 4-phenylbutyric acid in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burrows, JA; Perlmutter, DH; Willis, LK1
Csermely, P; Papp, E1
Kador, PF; Madson, CJ; Mulhern, ML; Randazzo, J; Shinohara, T1
Leandro, J; Leandro, P; Nascimento, C; Tavares de Almeida, I1
Chamcheu, JC; Gester, T; Moustakas, A; Mouyobo, CE; Navsaria, H; Pihl-Lundin, I; Törmä, H; Vahlquist, A; Virtanen, M1
Belyaeva, OV; Kedishvili, NY; Lee, SA1
Lupachyk, S; Obrosova, IG; Shevalye, H; Stavniichuk, R; Watcho, P1
Agrawal, A; Chakraborty, K; Chakraborty, S; Ghosh, B; Krishnan, V; Mabalirajan, U; Maity, S; Makhija, L; Rehman, R1
Jahani, Y; Mohammadi, A; Najar, AG; Vahabzadeh, Z; Yaghoobi, MM1

Other Studies

9 other study(ies) available for trimethyloxamine and 4-phenylbutyric acid

ArticleYear
Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Feb-15, Volume: 97, Issue:4

    Topics: Administration, Oral; alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Animals; Cell Line; Emphysema; Glycerol; Humans; Liver; Lung; Methylamines; Mice; Mice, Transgenic; Mutation; Phenylbutyrates; Protein Folding; Temperature

2000
Chemical chaperones: mechanisms of action and potential use.
    Handbook of experimental pharmacology, 2006, Issue:172

    Topics: Animals; Enzyme Inhibitors; Glycerol; Humans; Methylamines; Molecular Chaperones; Phenylbutyrates; Protein Folding

2006
Cellular osmolytes reduce lens epithelial cell death and alleviate cataract formation in galactosemic rats.
    Molecular vision, 2007, Aug-10, Volume: 13

    Topics: Animals; Body Weight; Cataract; Cell Death; Cell Survival; Cells, Cultured; Disease Models, Animal; Endoplasmic Reticulum; Epithelial Cells; Galactose; Galactosemias; Humans; Lens, Crystalline; Methylamines; Phenylbutyrates; Protein Folding; Rats; Rats, Sprague-Dawley; Sodium Selenite; Taurochenodeoxycholic Acid; Tunicamycin; Up-Regulation

2007
Modulation of the activity of newly synthesized human phenylalanine hydroxylase mutant proteins by low-molecular-weight compounds.
    The protein journal, 2008, Volume: 27, Issue:6

    Topics: Animals; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Enzymologic; Glycerol; Humans; Methylamines; Mutant Proteins; Phenylalanine Hydroxylase; Phenylbutyrates; Phenylketonurias; Recombinant Fusion Proteins; Temperature

2008
Immortalized keratinocytes derived from patients with epidermolytic ichthyosis reproduce the disease phenotype: a useful in vitro model for testing new treatments.
    The British journal of dermatology, 2011, Volume: 164, Issue:2

    Topics: Adolescent; Adult; Cell Line; Cell Transformation, Viral; Epidermis; Hot Temperature; HSP70 Heat-Shock Proteins; Humans; Hyperkeratosis, Epidermolytic; Keratinocytes; Keratins; Male; Methylamines; Models, Biological; Phenotype; Phenylbutyrates; Stress, Physiological; Young Adult

2011
Evidence that proteosome inhibitors and chemical chaperones can rescue the activity of retinol dehydrogenase 12 mutant T49M.
    Chemico-biological interactions, 2011, May-30, Volume: 191, Issue:1-3

    Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Biocatalysis; Dimethyl Sulfoxide; HEK293 Cells; Humans; Methylamines; Molecular Sequence Data; Molecular Weight; Mutant Proteins; Mutation; Phenylbutyrates; Protease Inhibitors; Proteasome Inhibitors

2011
Endoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathy.
    Diabetes, 2013, Volume: 62, Issue:3

    Topics: Animals; CCAAT-Enhancer-Binding Proteins; Diabetic Neuropathies; Endoplasmic Reticulum Stress; Epidermis; Male; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Molecular Targeted Therapy; Nerve Tissue Proteins; Phenylbutyrates; Random Allocation; Rats; Rats, Wistar; Sciatic Nerve; Spinal Cord; Streptozocin; Unfolded Protein Response; Up-Regulation

2013
Chemical chaperones mitigate experimental asthma by attenuating endoplasmic reticulum stress.
    American journal of respiratory cell and molecular biology, 2014, Volume: 50, Issue:5

    Topics: Airway Remodeling; Animals; Asthma; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Glycerol; Inflammation; Lung; Male; Methylamines; Mice; Mice, Inbred BALB C; Molecular Chaperones; Phenylbutyrates; Protein Folding; Trehalose; Unfolded Protein Response

2014
Trimethylamine-N-Oxide Treatment Induces Changes in the ATP-Binding Cassette Transporter A1 and Scavenger Receptor A1 in Murine Macrophage J774A.1 cells.
    Inflammation, 2016, Volume: 39, Issue:1

    Topics: Animals; Atherosclerosis; ATP Binding Cassette Transporter 1; Cell Line; Endoplasmic Reticulum Stress; Foam Cells; Macrophages; Methylamines; Mice; Phenylbutyrates; RNA, Messenger; Scavenger Receptors, Class A; Tunicamycin; Up-Regulation

2016