trimethylamine and trimethyloxamine

trimethylamine has been researched along with trimethyloxamine in 235 studies

Research

Studies (235)

TimeframeStudies, this research(%)All Research%
pre-199022 (9.36)18.7374
1990's25 (10.64)18.2507
2000's17 (7.23)29.6817
2010's63 (26.81)24.3611
2020's108 (45.96)2.80

Authors

AuthorsStudies
Ho, YS; Lin, JK1
al-Waiz, M; Mikov, M; Mitchell, SC; Smith, RL1
Anthoni, U; Christophersen, C; Gram, L; Nielsen, NH; Nielsen, P1
Fennessey, P; Tjoa, S1
Gamati, S; Luong, JH; Mulchandani, A1
Arrigoni Martelli, E; Marzo, A; Monti, N; Muck, S; Ripamonti, M1
daCosta, KA; Vrbanac, JJ; Zeisel, SH1
al-Waiz, M; Ayesh, R; Idle, JR; Mitchell, SC; Smith, RL4
daCosta, KA; Hensey, S; Youssef, M; Zeisel, SH1
Hurng, DC; Lin, JK3
Charest, RP; Chenoweth, M; Dunn, A1
Al-Waiz, M; Idle, JR; Mitchell, SC; Smith, RL1
Benge, LC; Miskin, DR; Owens, JD; Wacher-Viveros, MC1
Barrett, EL; Kwan, HS1
Hansen, RC; Rothschild, JG1
Charest, R; Dunn, A1
Abeling, NG; Bakker, HD; Engelke, U; Heerschap, A; van Gennip, AH; Wevers, RA1
Atkinson, S; Cholerton, S; Hadidi, HF; Idle, JR; Irshaid, YM; Rawashdeh, NM1
Akesson, B; Nilsson, A; Paulsson, K; Svensson, BG1
Deen, WM; Smith, JL; Wishnok, JS1
Dalgaard, P; Gram, L; Huss, HH1
Ayesh, R; Mitchell, SC; Smith, RL; Zhang, A1
Guppy, M; Withers, PC1
Mitchell, S; Smith, R; Zhang, AQ1
Ellory, JC; Flanagan, GJ; O'Kelly, J; Rae, C; Winearls, CG1
Mitchell, SC; Smith, RL; Zhang, AQ3
Akyol, D; Cholerton, S; Gökmen, O; Green, RL; Mellon, T; Sardas, S1
Azaroual, N; Boulet, O; Crunelle, V; Foulard, M; Imbenotte, M; Lhermitte, M; Maschke, S; Vermeersch, G; Wahl, A1
Thithapandha, A1
Dalgaard, P; Gram, L; Huss, HH; Paludan-Müller, C1
Eugène, M1
Choinière, L; Mamer, OA; Treacy, EP1
Mayatepek, E; Zschocke, J1
Damani, LA; Lee, CW; Lin, G; Tomlinson, B; Yeung, JH1
Ashton, GH; Eldridge, P; Fraser-Andrews, EA; Manning, NJ; McGrath, J; Menagé, Hdu P1
Abugoch, L; Guarda, A; Larraín, MA; Quitral Robles, V; Santana, G; Vinagre, J1
WRANNE, L1
VAISEY, EB1
Biltz, CI; Chidsey, CA; Cohen, JJ; Krupp, MA1
BAKER, J; CHAYKIN, S1
BAKER, JR; CHAYKIN, S1
BEMM, H; ROTZSCH, W1
BAKER, JR; CHAYKIN, S; STRUEMPLER, A1
BEMM, H; ROTZSCH, W; STRACK, E1
Cashman, JR; Fujieda, M; Kamataki, T; Preti, G; Saito, T; Togashi, M; Yamazaki, H1
El Abed, A; M'Hetli, M; Sadok, S; Uglow, RF1
Bain, MA; Evans, AM; Faull, R; Fornasini, G; Milne, RW; Schumann, R1
Arêas, JA; Lanfer-Marquez, UM; Podadera, P; Sipahi, AM1
Bain, MA; Evans, AM; Faull, R; Fornasini, G; Milne, RW1
Bain, MA; Evans, AM; Milne, RW1
Bain, MA; Evans, AM; Faull, R; Milne, RW1
Bollard, ME; Mitchell, SC; Zhang, A1
Chao, MC; Hsu, WY; Lai, CC; Lin, WD; Lo, WY; Tsai, CH; Tsai, FJ; Tsai, Y1
Johnson, DW1
Chang, YG; Li, F; Liu, HY; Xin, XQ; Xu, J; Xue, CH; Xue, Y; Yin, LA1
Kozono, M; Murayama, N; Shimizu, M; Yamazaki, H1
Liffourrena, AS; Lucchesi, GI; Salvano, MA1
Choinière, L; Lesimple, A; Mamer, OA1
Huang, C; Lei, H; Nie, X; Tang, H; Wang, Y; Zhao, XJ1
Aslam, M; Felix, P; Puthi, V1
Allayee, H; Bennett, BJ; Crooke, R; de Aguiar Vallim, TQ; Edwards, PA; Graham, M; Gregory, J; Hazen, SL; Lee, R; Lusis, AJ; Meng, Y; Shih, DM; Wang, Z1
Miller, MJ1
Arduini, A; Lopaschuk, GD; Ussher, JR1
Chan, BT; Chung, SW1
Chen, Y; Lidbury, ID; Murrell, JC1
Hazen, SL; Tang, WH1
Bruschetta, D; D'Angelo, R; Esposito, T; Rinaldi, C; Ruggeri, A; Scimone, C; Sidoti, A1
Bennett, BJ; Brown, JM; Charugundla, S; Che, N; Graham, M; Hazen, SL; Lee, R; Lusis, AJ; Meng, Y; Pan, C; Qi, H; Shih, DM; Vallim, T; Wang, Z; Wu, J1
Bennett, BJ; Buffa, JA; DiDonato, JA; Gregory, JC; Hazen, SL; Levison, BS; Li, L; Lusis, AJ; Org, E; Wagner, MA; Wang, Z; Zhu, W1
Abbara, S; Boccara, F; Capeau, J; Fitch, KV; Gauguier, D; Grinspoon, SK; Kadar, H; Knight, R; Lo, J; Srinivasa, S; Wong, K1
Faria, A; Oliva, M; Oliveira, A1
Aukrust, P; Berge, RK; Haissman, JM; Hoel, H; Katzenstein, TL; Kjær, A; Knudsen, A; Kristoffersen, US; Lebech, AM; Nielsen, SD; Svardal, A; Trøseid, M; Ueland, T1
Liu, TX; Niu, HT; Zhang, SY1
Allenspach, M; Linseisen, J; Müller, D; Rohrmann, S; von Eckardstein, A1
Awwad, HM; Geisel, J; Graeber, S; Herrmann, W; Obeid, R; Rabagny, Y1
Chen, ML; Mi, MT; Ran, L; Yang, J; Yi, L; Zhang, QY; Zhang, Y; Zhou, X; Zhu, JD1
Bhargava, B; Chhibber-Goel, J; Gaur, A; Parakh, N; Sharma, A; Singhal, V1
Hennig, B; Hoffman, JB; Morris, AJ; Perkins, JT; Petriello, MC; Sunkara, M; Wahlang, B1
Spector, R1
Fennema, D; Phillips, IR; Shephard, EA1
Awwad, HM; Geisel, J; Keller, M; Obeid, R1
Ge, Y; Yang, Y; Ye, X; Zhu, J1
Awwad, HM; Geisel, J; Obeid, R1
Chmurzynska, A; Malinowska, AM; Szwengiel, A1
Curtis, JM; Jacobs, RL; Mi, S; Zhao, YY1
Chen, XL; Chen, Y; Li, CY; Li, PY; Peng, M; Qin, QL; Sheng, Q; Shi, M; Song, XY; Su, HN; Wang, P; Xie, BB; Xun, LY; Zhang, D; Zhang, XY; Zhang, YZ; Zhou, BC1
Fricker, G; Garbade, SF; Kratzer, F; Langhans, CD; Okun, JG; Schmidt, KV; Schuhmann, V; Stremmel, W1
Chen, ZY; He, Z1
Shimizu, M; Yamazaki, H1
He, H; Lian, X; Tang, Z1
Li, Q; Liu, R; Wang, R; Wu, T; Zhang, M1
Dias, CL; Mahmoudinobar, F; Su, Z1
Kellermann, G; Li, S; Li, XS1
Grinberga, S; Hartmane, D; Kalnins, G; Sevostjanovs, E; Tars, K1
Castrignanò, S; Catucci, G; Gao, C; Gilardi, G; Sadeghi, SJ1
Aadland, EK; Bertram, HC; Brejnrod, AD; Eng, Ø; Graff, IE; Holthe, A; Jacques, H; Kiilerich, P; Kristiansen, K; Lavigne, C; Liaset, B; Mellgren, G; Schmedes, M; Sundekilde, UK; Young, JF1
Allayee, H; Buffa, JA; Cajka, T; DiDonato, JA; Fiehn, O; Gu, X; Han, Y; Hartiala, JA; Hazen, SL; Hurd, AG; Kerby, RL; Li, L; Li, XS; Lüscher, TF; Nemet, I; Obeid, S; Rey, FE; Roberts, AB; Romano, KA; Shahen, CJ; Skye, SM; Tang, WHW; Wagner, MA; Wang, Z; Wu, Y1
Bergman, P; Borges, NA; Lindholm, B; Mafra, D; Moraes, C; Qureshi, AR; Stenvinkel, P; Stockler-Pinto, MB1
Kusama, T; Miura, T; Mizuno, S; Shimizu, M; Suemizu, H; Uehara, S; Yamazaki, H1
Brigidi, P; Candela, M; Fiori, J; Gotti, R; Turroni, S1
Angiletta, CJ; Baer, DJ; Davy, KP; Griffin, LE; Neilson, AP; Novotny, JA; Steele, CN1
DiDonato, JA; Fischbach, MA; Guo, CJ; Haag, B; Hazen, SL; Jia, X; Kirsop, J; Lang, JM; Lusis, AJ; Rey, FE; Romano, KA; Skye, SM; Tang, WHW; Wang, Z; Zhu, W1
Abidin, S; Bhandari, U; Gautam, A; Paudel, YN1
Bartlett, D; Cody, DB; Copeland, MF; Culley, MK; Dai, HJ; DiDonato, JA; Fu, X; Garcia-Garcia, JC; Gu, X; Hazen, SL; Kirsop, J; Koeth, RA; Lam-Galvez, BR; Levison, BS; Li, L; Li, XS; Tang, WHW; Wang, Z; Wu, Y1
Rodger, M; Versteeg, HH1
Allayee, H; Brown, JM; Cantor, RM; Graham, M; Hazen, SL; Jia, X; Lee, R; Lusis, AJ; Meng, Y; Miikeda, A; Mueller, C; Schugar, RC; Shih, DM; Wang, Z; Zhu, W; Zieger, M1
Catucci, G; Gilardi, G; Sadeghi, SJ1
Chen, L; Wu, J; Yang, H; Zhao, X1
Chen, C; Chen, Y; Gu, A; Guo, W; Hu, H; Jiang, Z; Jiao, L; Liu, Q; Lu, Q; Shao, W; Sun, H; Wang, Q; Weng, Z1
Chen, PY; Ho, CT; Koh, YC; Li, S; Pan, MH; Wu, JC; Yang, MJ1
Chang-Chien, GP; Hou, CY; Hsu, CN; Lin, S; Tain, YL2
Ge, J; Jia, D; Jiang, H; Ou, T; Qi, Z; Qian, J; Sun, A; Yang, W; Zhang, S; Zhu, J; Zou, Y1
Bielak-Zmijewska, A; Grochowska, M; Hutsch, T; Jaworska, K; Konop, M; Mosieniak, G; Perlejewski, K; Radkowski, M; Sikora, E; Ufnal, M1
Bielak-Zmijewska, A; Filipiak, K; Gasecka, A; Hering, D; Hołyst, R; Jaworska, K; Kapłon-Cieślicka, A; Konwerski, M; Mosieniak, G; Pilz, M; Sikora, E; Ufnal, M1
Bielinska, K; Gawrys-Kopczynska, M; Jaworska, K; Ufnal, M1
Wu, Q; Yang, X; Zhang, X; Zhao, Y1
Din, AU; Gregersen, H; Hassan, A; Wang, G; Yin, T; Zhu, Y1
Fudge, DS; Hoang, C; Jain, G; McCord, C; Singh, K; Starksen, M; Yancey, P1
Aguesse, A; Billon-Crossouard, S; Croyal, M; Ene, L; Guebre-Egziabher, F; Juillard, L; Krempf, M; Lemoine, S; Pelletier, CC; Soulage, CO1
Leblond, FA; Nolin, TD; Pichette, V; Prokopienko, AJ; Schrum, DP; Stubbs, JR; West, RE1
Arachchige, BJ; Aylward, J; Henderson, R; Lee, A; McCombe, PA; Reed, S1
Anderson, JLC; Hoek, A; Homminga, I; Jia, C; Liu, F; Nagy, RA; Tietge, UJF1
Dai, Q; Liu, Y; Zhang, H1
Ufnal, M1
Liu, J; Lv, Z; Si, C; Wang, RT; Wang, X; Wang, Y; Zhang, T1
Arnal, ME; Brugère, JF; Camponova, P; Fadhlaoui, K; Martineau, M; O'Toole, PW; Ollivier, B1
Chen, PY; Chen, S; Fang, AP; Jiang, PP; Li, CL; Liao, GC; Liu, ZY; Long, JA; Luo, Y; Wang, XY; Wu, SL; Yu, D; Zhang, DM; Zhong, RH; Zhu, HL1
Auger, J; Dahl, WJ; Ford, AL; Hung, WL; Nagulesapillai, V; Suh, JH; Wang, Y1
Folberth, A; Heyda, J; Polák, J; van der Vegt, NFA1
Jo, DM; Khan, F; Kim, YM; Lee, YB; Park, SK; Yu, D1
García-Cañas, V; Simó, C1
Rossing, P; Winther, SA1
Chen, C; He, Y; Huang, Z; Lei, W; Liang, Z; Luo, H; Qi, Y; Shui, X; Zhu, Y1
Han, C; Jiao, J; Li, J; Liu, X; Liu, Z; Wang, P; Yang, X; Yin, X; Zuo, K1
Allison, J; Arboleya, S; Arias, JL; Arias, N; Gueimonde, M; Higarza, SG; Kaliszewska, A1
Hwang, KT; Lee, K; Lim, T; Park, SY; Ryu, J1
Chabowski, D; Drapala, A; Jaworska, K; Kraszewska, K; Mogilnicka, I; Samborowska, E; Szudzik, M; Ufnal, M1
Dambrova, M; Grinberga, S; Kuka, J; Liepins, J; Liepinsh, E; Makrecka-Kuka, M; Sevostjanovs, E; Videja, M; Vilks, K1
Baranyi, A; Enko, D; Herrmann, M; Meinitzer, A; Zelzer, S1
Shimizu, M; Uno, Y; Utoh, M; Yamazaki, H1
Almendral, D; Barbas, C; Bjerga, GEK; Claussen, J; Ferrer, M; Garcia-Moyano, A; Goris, M; Larsen, Ø; Puntervoll, P; Rojo, D1
Aukrust, P; Berge, RK; Dahl, TB; Fevang, B; Halvorsen, B; Holm, K; Hov, JR; Jørgensen, SF; Kummen, M; Macpherson, ME; Mollnes, TE; Otterdal, K; Trøseid, M; Ueland, T1
Fink, GD; Restini, CBA; Watts, SW1
He, M; Liu, Y; Tan, CP; Xu, YJ1
Bernieh, D; Cassambai, S; Heaney, LM; Israr, MZ; Jones, DJL; Ng, LL; Salzano, A; Suzuki, T; Yazaki, Y1
Chen, GY; Chepyala, D; Chiu, HH; Kuo, CH; Kuo, HC; Lu, WH1
Chen, XL; Chen, Y; Fang, J; Li, CY; Li, PY; Lidbury, I; Miao, J; Qin, QL; Su, HN; Wang, M; Wang, XJ; Wang, ZB; Yang, GP; Zhang, W; Zhang, XH; Zhang, XY; Zhang, YZ1
Argyridou, S; Bernieh, D; Biddle, GJH; Davies, MJ; Dawkins, NP; Khunti, K; Rowlands, AV; Smith, AC; Suzuki, T; Yates, T1
Du, Y; Hong, B; Jiang, J; Jiang, Z; Li, X; Su, C; Wang, L; Yang, M; Yang, Y; Zhang, J; Zhang, X; Zhang, Y1
Mueller, NT; Tilves, C1
Aucejo, F; Brown, JM; Choucair, I; Claesen, J; DeLucia, B; Fung, K; Horak, AJ; Massey, W; Orabi, D; Osborn, LJ; Wang, Z1
Bakker, SJL; Connelly, MA; Dullaart, RPF; Flores-Guerrero, JL; Garcia, E; Navis, G; Post, A; van Dijk, PR1
He, S; Jiang, H; Jiang, W; Zhuo, C1
Chen, J; He, F; Liu, S; Pei, X; Wan, S; Xu, X; Yang, F; Zheng, T1
Bergström, M; Fagerström, C; Hefni, ME; Lennqvist, T; Witthöft, CM1
Andres, CR; Antar, C; Benz-de-Bretagne, I; Blasco, H; Bruno, C; Clavier, V; Hennart, B; Maillot, F; Nadal-Desbarats, L; Veyrat-Durebex, C1
Le, J; Li, Y; Peng, R1
Cao, Z; Guo, X; Liu, L; Wang, X; Xie, C; Yang, P; Zhang, Q1
Chang, YC; Chu, YH; Tain, YL; Wang, CC; Wang, CH; Yang, HW1
Dalal, N; Jalandra, R; Khosla, A; Kumar, A; Sharma, M; Singh, R; Solanki, PR; Verma, D; Yadav, AK1
Chang, D; Dong, J; Ma, T; Nie, J; Xu, X; Yang, Z1
Buawangpong, N; Chattipakorn, N; Chattipakorn, SC; Pinyopornpanish, K; Siri-Angkul, N1
Chen, Z; Cui, M; Fang, H; Li, Y; Liu, M; Lü, S; Qi, H; Sun, J; Wei, Q; Zhang, J; Zhao, L1
Chen, G; Dou, X; He, L; Liu, T1
Aulisa, G; Lombardo, M; Marcon, D; Rizzo, G1
Cao, P; Chen, Q; Deng, W; Gong, Z; Guo, J; Li, X; Pei, M; Shi, C; Wang, L; Wang, Y; Zhang, L1
Allen, FM; Anderson, JT; Armstrong, AR; Banerjee, R; Brown, AL; Brown, JM; Buffa, JA; Burrows, A; Cook, K; Ferguson, D; Finney, C; Fung, KK; Garcia-Garcia, JC; Gliniak, CM; Goudarzi, M; Gromovsky, AD; Hazen, SL; Helsley, RN; Horak, A; Keshavarzian, A; Lusis, AJ; Mak, TD; Massey, W; McMillan, A; Mehrabian, M; Neumann, C; Orabi, D; Osborn, LJ; Sangwan, N; Schugar, RC; Swanson, G; Wang, Z; Willard, B1
Chen, CC; Chen, PC; Chen, RA; Chong, KV; Chuang, HL; Chung, CH; Ho, CT; Hsu, CC; Huang, HS; Huang, TF; Kao, HL; Lin, AY; Liu, PY; Orekhov, AN; Panyod, S; Sheen, LY; Shen, TD; Wu, MS; Wu, WK; Yang, KC; Yang, YT1
Daschakraborty, S; Maiti, A1
Chan, Q; Holmes, E; Loo, RL; Nicholson, JK1
Dey, M; Dhakal, S; Moazzami, Z; Perry, C1
Bo, Y; Bogaert, D; Cai, X; Chen, J; Fang, A; He, D; He, Y; Larsson, SC; Li, D; Li, X; Lu, Y; Song, P; Theodoratou, E; Tsilidis, K; Wu, Q; Yu, H; Yuan, S; Zhu, H; Zhu, Y1
Abdi, M; Ghaderi, D; Moloudi, MR; Moradzad, M; Rahmani, K; Sheikh Esmaeili, F; Vahabzadeh, Z1
Yao, G; Zhang, H1
Budnik, M; Czub, P; Filipiak, KJ; Gąsecka, A; Huczek, Z; Kapłon-Cieślicka, A; Kochanowski, J; Kochman, J; Konop, M; Konwerski, M; Opolski, G; Rzepa, Ł; Scisło, P; Ufnal, M; Wilczyńska-Burlikowska, J; Wilimski, R; Wondołkowski, M; Wysocki, K; Zawadzka, M1
Bean, LD; Harris, RE; Milks, MW; Raman, SV; Smart, SM; Wing, JJ1
Chen, LP; Shi, HH; Wang, CC; Wang, YM; Xue, CH; Zhang, TT; Zhao, YC1
Alagha, EC; Anderson, KM; Ferranti, EP; French, CE; Mykityshyn, E; Reilly, CM1
Chao, CY; Chiang, EI; Chiang, ER; Chiu, SC; Hung, HC; Rodriguez, RL; Syu, JN; Tang, FY; Wang, WJ1
Huang, JL; Ma, YY; Tang, TJ; Wang, L; Wang, SS; Zhao, XN; Zhou, P1
Anand, N; Chandana, KA; Chidambaram, SB; Kalyan, M; Kanna, PV; Mahalakshmi, AM; Pandi-Perumal, SR; Praveenraj, SS; Sakharkar, MK; Shasthara, P; Sonali, S; Tousif, HA; Vichitra, C; Yang, J1
Ren, Y; Wang, Z; Xue, J1
Hong, Y; Ji, N; Luo, X; Ma, W; Nie, Z; Shan, J; Xue, J; Zhang, T; Zhang, Y; Zhou, S; Zhu, W1
Chang, X; Dai, Y; Duan, Z; Guo, J; Qi, X; Tan, R; Wang, Z; Wu, C; Xu, S; Zhang, J; Zhang, Q; Zhou, Z1
Kobayashi, T; Matsumoto, T; Osada, T; Taguchi, K; Taguchi, N; Yoshioka, M1
Cao, Y; Chang, X; Dai, Y; Guo, J; Liang, W; Lu, D; Lv, S; Qi, X; Wang, Z; Wu, C; Zhang, J; Zhang, L; Zhou, Z1
Buawangpong, N; Chattipakorn, N; Chattipakorn, SC; Chindapan, N; Devahastin, S; Phrommintikul, A; Pinyopornpanish, K1
Ding, BS; Mo, C; Xiao, C; Zhang, J; Zhou, D1
Feng, YQ; He, GD; Liu, XC; Lu, AS1
Chen, M; Ou, C; Zhang, J1
Chen, D; Hong, Q; Huang, G; Que, D; Yan, J; Yang, P; Zhai, W; Zhong, C1
Anutrakulchai, S; Cha'on, U; Hammock, BD; Kyaw, TS; Lert-Itthiporn, W; Nahok, K; Pinlaor, S; Sangkhamanon, S; Sansurin, N; Selmi, C; Senthong, V; Sharma, A; Silsirivanit, A; Sukmak, M1
Cheng, A; Jiang, X; Jin, A; Li, H; Li, K; Lin, J; Meng, X; Wang, Y; Xu, J; Xue, J; Zhao, M; Zheng, L1
Fu, L; Hao, Y; Wang, N1
Chen, C; Ding, L; Guo, J; Liu, H; Ma, Y; Qiao, X; Wang, J; Wang, M; Yang, T; Zhao, S1
Gawryś-Kopczyńska, M; Maksymiuk, KM; Mogilnicka, I; Onyszkiewicz, M; Samborowska, E; Szudzik, M; Ufnal, M1
Blanco, R; Daimiel, L; Dávalos, A; Díez-Ricote, L; Micó, V; Ordovás, JM; Ruiz-Valderrey, P; Tomé-Carneiro, J1
Boon, MR; Fan, X; Li, Z; Liu, C; Rensen, PCN; Schönke, M; Shao, H; Song, Z; Wang, Y1
He, L; Yang, P; Yang, W; Zhang, A; Zhang, X1
Wang, N; Wu, Q; Yang, X; Zhang, L; Zhao, Y1
Gui, XY; Rabkin, SW1
Huang, Y; Liu, J; Peng, L; Tang, C; Wang, H; Wei, X; Yuan, X1
Le, G; Li, B; Lu, M; Wang, X; Xie, Y; Xu, Y; Yang, Y1
Lizogub, VG; Melnychuk, I1
Gao, K; Ge, HW; Huang, GS; Sun, QM; Yong, C; Zhou, EC1
Dong, Z; Lao, Y; Li, B; Li, G; Li, R; Wang, W; Wang, Y; Zhao, C1
Jensen, PN; Lemaitre, RN; Mozaffarian, D1
Al-Arawe, N; El Hage, R; Hinterseher, I1
Bao, Y; Huang, D; Jiang, L; Qv, S; Wang, J; Wang, L; Xu, G; Yang, J; Zhan, X1
Guo, X; He, S; He, Y; Li, L; Liang, W; Lin, X; Wang, J; Xiao, Y; Xiong, Q; Ying, C; Zhao, J; Zuo, X1
Dinan, TG; DunnGalvin, G; Duss, R; Duttaroy, AK; Fehlbaum, S; Guy, B; Panagos, CG; Patel, S; Rehman, A; Steinert, RE; Tyree, SM1
Jiang, F; Ren, X; Zhang, Y; Zhou, P; Zhuang, H1
Ancuta, B; Cismaru, G; Decea, N; Filip, GA; Florea, CM; Moldovan, R; Rosu, R; Toma, V; Vlase, L1
Lazar, M; Olma, A; Streb, W1
Bariskaner, H; Celik, C; Ongun, MC; Orgul, G1
Baldea, I; Decea, N; Filip, GA; Florea, CM; Moldovan, R; Rosu, R1
Almendral, D; Bjerga, GEK; Cea-Rama, I; Ferrer, M; Goris, M; Puntervoll, P; Ree, R; Sanz-Aparicio, J1
Arnindita, JN; Dyah Lamara, A; Oktaviono, YH; Pasahari, D; Saputra, ME; Saputra, PBT; Suasti, NMA1
Chiang, EI; Huang, TY; Lee, DY; Lin, HY; Syu, JN; Tang, FY1
Aziz, F; Curcic, P; Hermann, M; Kolesnik, E; Mangge, H; Meinitzer, A; Pferschy, PN; Sourij, H; Tripolt, NJ; von Lewinski, D1
Chadwick-Corbin, SA; Iglesias-Carres, L; Neilson, AP; Sweet, MG1
Budoff, M; de Oliveira Otto, MC; Fretts, AM; Hazen, SL; Jensen, PN; Lemaitre, RN; Longstreth, WT; Mozaffarian, D; Nemet, I; Psaty, BM; Siscovick, DS; Sitlani, CM; Sotoodehnia, N; Wang, Z; Zhu, W1
Bergman, P; Craven, H; Erlandsson, H; Ijaz, UZ; Mafra, D; McGuinness, D; McGuinness, DH; Shiels, PG; Stenvinkel, P1
Chen, ZY; He, Z; Kwek, E; Liu, J; Ma, KY; Zhu, H1
An, JP; Lee, H; Liu, X; Wang, Y1
Duan, Y; Guo, Z; Hong, Y; Li, Y; Liu, N; Sun, Z; Xu, Q; Yang, K1
Bellanger, S; Cheong, KH; Chin, YL; Devasia, AG; Leo, CH; Ong, ES; Ramasamy, A; Shanmugham, M1

Reviews

31 review(s) available for trimethylamine and trimethyloxamine

ArticleYear
Bacterial reduction of trimethylamine oxide.
    Annual review of microbiology, 1985, Volume: 39

    Topics: Bacteria; Dimethyl Sulfoxide; Enterobacteriaceae; Methylamines; Mutation; Oxidation-Reduction; Oxidoreductases; Rhodopseudomonas; Vibrio

1985
Gut microbiota metabolism of L-carnitine and cardiovascular risk.
    Atherosclerosis, 2013, Volume: 231, Issue:2

    Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Diet; Dietary Supplements; Humans; Insulin Resistance; Intestines; Liver; Methylamines; Mice; Microbiota; Muscle, Skeletal; Myocardial Ischemia; Phosphatidylcholines; Risk

2013
The contributory role of gut microbiota in cardiovascular disease.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:10

    Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Choline; Diet; Female; Food; Humans; Intestines; Male; Methylamines; Microbiota; Oxygenases; Phosphatidylcholines

2014
Intestinal Microbiota Metabolism and Atherosclerosis.
    Chinese medical journal, 2015, Oct-20, Volume: 128, Issue:20

    Topics: Atherosclerosis; Gastrointestinal Microbiome; Humans; Methylamines

2015
The complex metabolism of trimethylamine in humans: endogenous and exogenous sources.
    Expert reviews in molecular medicine, 2016, Apr-29, Volume: 18

    Topics: Air Pollutants; Animals; Atherosclerosis; Diet; Humans; Metabolism, Inborn Errors; Methylamines; Neoplasms; Odorants; Renal Insufficiency; Risk Factors; Thrombosis

2016
New Insight into the Dietary Cause of Atherosclerosis: Implications for Pharmacology.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 358, Issue:1

    Topics: Animals; Cholesterol; Coronary Artery Disease; Diet; Diet, Vegetarian; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Arteriosclerosis; Meta-Analysis as Topic; Methylamines; Practice Guidelines as Topic

2016
Trimethylamine and Trimethylamine N-Oxide, a Flavin-Containing Monooxygenase 3 (FMO3)-Mediated Host-Microbiome Metabolic Axis Implicated in Health and Disease.
    Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:11

    Topics: Animals; Cardiovascular Diseases; Gastrointestinal Microbiome; Host-Pathogen Interactions; Humans; Methylamines; Oxygenases

2016
Amelioration of TMAO through probiotics and its potential role in atherosclerosis.
    Applied microbiology and biotechnology, 2019, Volume: 103, Issue:23-24

    Topics: Animals; Atherosclerosis; Humans; Metabolomics; Methylamines; Mice; Microbiota; MicroRNAs; Probiotics

2019
Archaea, specific genetic traits, and development of improved bacterial live biotherapeutic products: another face of next-generation probiotics.
    Applied microbiology and biotechnology, 2020, Volume: 104, Issue:11

    Topics: Animals; Archaea; Biological Therapy; Cardiovascular Diseases; Diet; Gastrointestinal Microbiome; Humans; Metabolism, Inborn Errors; Methylamines; Mice; Probiotics

2020
Dietary bioactive ingredients to modulate the gut microbiota-derived metabolite TMAO. New opportunities for functional food development.
    Food & function, 2020, Aug-01, Volume: 11, Issue:8

    Topics: Betaine; Biological Availability; Carnitine; Choline; Diet; Food Ingredients; Functional Food; Gastrointestinal Absorption; Gastrointestinal Microbiome; Gastrointestinal Tract; Heart Disease Risk Factors; Humans; Liver; Methylamines; Oxygenases

2020
Gut microbiota metabolites as integral mediators in cardiovascular diseases (Review).
    International journal of molecular medicine, 2020, Volume: 46, Issue:3

    Topics: Amino Acids; Animals; Bile Acids and Salts; Cardiovascular Diseases; Fatty Acids; Gastrointestinal Microbiome; Humans; Metabolic Networks and Pathways; Methylamines; Risk Factors

2020
The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases.
    Nutrients, 2020, Aug-05, Volume: 12, Issue:8

    Topics: Animals; Biological Availability; Cardiovascular Diseases; Choline; Diet; Dysbiosis; Gastrointestinal Microbiome; Genotype; Humans; Inflammatory Bowel Diseases; Liver; Methylamines; Non-alcoholic Fatty Liver Disease; Renal Insufficiency, Chronic

2020
Gut microbiota-derived trimethylamine-N-oxide: A bridge between dietary fatty acid and cardiovascular disease?
    Food research international (Ottawa, Ont.), 2020, Volume: 138, Issue:Pt B

    Topics: Cardiovascular Diseases; Fatty Acids; Gastrointestinal Microbiome; Humans; Methylamines; Oxides

2020
Trimethylamine/Trimethylamine-N-Oxide as a Key Between Diet and Cardiovascular Diseases.
    Cardiovascular toxicology, 2021, Volume: 21, Issue:8

    Topics: Animals; Bacteria; Cardiovascular Diseases; Diet; Gastrointestinal Microbiome; Heart Disease Risk Factors; Humans; Methylamines; Risk Assessment

2021
Emerging role of trimethylamine-N-oxide (TMAO) in colorectal cancer.
    Applied microbiology and biotechnology, 2021, Volume: 105, Issue:20

    Topics: Colorectal Neoplasms; Humans; Methylamines; Oxides

2021
The role of trimethylamine-N-Oxide in the development of Alzheimer's disease.
    Journal of cellular physiology, 2022, Volume: 237, Issue:3

    Topics: Alzheimer Disease; Animals; Choline; Methylamines; Oxides

2022
[Gut microbiota and its metabolite trimethylamine-N-oxide (TMAO): a novel regulator in coronary artery disease].
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2021, Nov-25, Volume: 37, Issue:11

    Topics: Coronary Artery Disease; Gastrointestinal Microbiome; Humans; Methylamines; Oxides

2021
Association of Trimethylamine-N-Oxide Levels with Risk of Cardiovascular Disease and Mortality among Elderly Subjects: A Systematic Review and Meta-Analysis.
    Cardiorenal medicine, 2022, Volume: 12, Issue:2

    Topics: Aged; Biomarkers; Cardiovascular Diseases; Heart Failure; Humans; Methylamines; Oxides; Prospective Studies; Renal Insufficiency, Chronic; Risk Factors

2022
The Influence of Animal- or Plant-Based Diets on Blood and Urine Trimethylamine-N-Oxide (TMAO) Levels in Humans.
    Current nutrition reports, 2022, Volume: 11, Issue:1

    Topics: Animals; Diet, Mediterranean; Diet, Vegan; Humans; Methylamines; Oxides

2022
Gut microbiota-derived metabolite trimethylamine-N-oxide and multiple health outcomes: an umbrella review and updated meta-analysis.
    The American journal of clinical nutrition, 2022, 07-06, Volume: 116, Issue:1

    Topics: Cardiovascular Diseases; Diabetes Mellitus; Gastrointestinal Microbiome; Humans; Hypertension; Methylamines; Neoplasms; Oxides; Risk Factors

2022
Significant correlation between the gut microbiota-derived metabolite trimethylamine-N-oxide and the risk of stroke: evidence based on 23 observational studies.
    European journal of clinical nutrition, 2023, Volume: 77, Issue:7

    Topics: Gastrointestinal Microbiome; Humans; Methylamines; Oxides; Risk Factors; Stroke

2023
The heart and gut relationship: a systematic review of the evaluation of the microbiome and trimethylamine-N-oxide (TMAO) in heart failure.
    Heart failure reviews, 2022, Volume: 27, Issue:6

    Topics: Heart Failure; Humans; Methylamines; Microbiota; Oxides; RNA, Ribosomal, 16S

2022
Virtual screening analysis of natural flavonoids as trimethylamine (TMA)-lyase inhibitors for coronary heart disease.
    Journal of food biochemistry, 2022, Volume: 46, Issue:12

    Topics: Coronary Disease; Flavonoids; Hesperidin; Humans; Lyases; Molecular Docking Simulation

2022
The Role of a Gut Microbial-Derived Metabolite, Trimethylamine N-Oxide (TMAO), in Neurological Disorders.
    Molecular neurobiology, 2022, Volume: 59, Issue:11

    Topics: Betaine; Carnitine; Choline; Flavins; Gastrointestinal Microbiome; Humans; Inflammasomes; Lyases; Methylamines; Mixed Function Oxygenases; Nervous System Diseases; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein

2022
[Gut-derived uremic toxin trimethylamine-N-oxide in cardiovascular disease under end-stage renal disease: an injury mechanism and therapeutic target].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2022, Aug-25, Volume: 39, Issue:4

    Topics: Cardiovascular Diseases; Humans; Kidney Failure, Chronic; Methylamines; Oxides; Uremic Toxins

2022
[Relationship between gut microbiota-derived substances and vascular function: focus on indoxyl sulfate and trimethylamine-N-oxide].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2022, Volume: 157, Issue:5

    Topics: Gastrointestinal Microbiome; Humans; Indican; Methylamines; Oxides

2022
C-Reactive Protein, Interleukin-6, Trimethylamine-N-Oxide, Syndecan-1, Nitric Oxide, and Tumor Necrosis Factor Receptor-1 in Heart Failure with Preserved Versus Reduced Ejection Fraction: a Meta-Analysis.
    Current heart failure reports, 2023, Volume: 20, Issue:1

    Topics: Biomarkers; C-Reactive Protein; Heart Failure; Humans; Interleukin-6; Natriuretic Peptide, Brain; Nitric Oxide; Prognosis; Proteomics; Stroke Volume; Syndecan-1

2023
[Effect of traditional Chinese medicine in attenuating chronic kidney disease and its complications by regulating gut microbiota-derived metabolite trimethylamine N-oxide: a review].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2023, Volume: 48, Issue:2

    Topics: Gastrointestinal Microbiome; Humans; Medicine, Chinese Traditional; Renal Insufficiency, Chronic

2023
The Role of the Gut Microbiome and Trimethylamine Oxide in Atherosclerosis and Age-Related Disease.
    International journal of molecular sciences, 2023, Jan-25, Volume: 24, Issue:3

    Topics: Aged; Aging; Animals; Atherosclerosis; Dysbiosis; Gastrointestinal Microbiome; Humans; Methylamines

2023
The roles of trimethylamine-N-oxide in atherosclerosis and its potential therapeutic aspect: A literature review.
    Biomolecules & biomedicine, 2023, Nov-03, Volume: 23, Issue:6

    Topics: Atherosclerosis; Choline; Endothelial Cells; Humans; Lyases; Oxides; Plaque, Atherosclerotic

2023
The relationship between trimethylamine-N-oxide and the risk of acute ischemic stroke: A dose‒response meta-analysis.
    PloS one, 2023, Volume: 18, Issue:10

    Topics: Humans; Ischemic Stroke; Methylamines; Oxides; Stroke

2023

Trials

18 trial(s) available for trimethylamine and trimethyloxamine

ArticleYear
The fish odour syndrome: biochemical, familial, and clinical aspects.
    BMJ (Clinical research ed.), 1993, Sep-11, Volume: 307, Issue:6905

    Topics: Adolescent; Adult; Animals; Female; Fishes; Humans; Infant; Male; Mental Disorders; Metabolism, Inborn Errors; Methylamines; Odorants; Pedigree; Syndrome

1993
Dietary precursors of trimethylamine in man: a pilot study.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1999, Volume: 37, Issue:5

    Topics: Adult; Choline; Diet; Humans; Male; Methylamines; Oxidants; Pilot Projects; Reference Values

1999
Effects of the dietary supplements, activated charcoal and copper chlorophyllin, on urinary excretion of trimethylamine in Japanese trimethylaminuria patients.
    Life sciences, 2004, Apr-16, Volume: 74, Issue:22

    Topics: Adult; Charcoal; Chlorophyllides; Diet; Dietary Supplements; Drug Therapy, Combination; Female; Humans; Japan; Male; Metabolism, Inborn Errors; Methylamines; Middle Aged; Treatment Outcome

2004
Disposition and metabolite kinetics of oral L-carnitine in humans.
    Journal of clinical pharmacology, 2006, Volume: 46, Issue:10

    Topics: Administration, Oral; Adult; Area Under Curve; Carnitine; Chromatography, High Pressure Liquid; Diarrhea; Dose-Response Relationship, Drug; Humans; Kidney; Male; Metabolic Clearance Rate; Methylamines; Nausea; Taste Disorders; Vitamin B Complex

2006
Oral L-carnitine: metabolite formation and hemodialysis.
    Current drug metabolism, 2006, Volume: 7, Issue:7

    Topics: Administration, Oral; Adult; Aged; Carnitine; Humans; Kidney Failure, Chronic; Male; Methylamines; Middle Aged; Renal Dialysis

2006
Trimethylamine-N-oxide and its biological variations in vegetarians.
    European journal of nutrition, 2017, Volume: 56, Issue:8

    Topics: Adult; Aged; Betaine; Biomarkers; Diet, Vegetarian; Female; Humans; Male; Methylamines; Middle Aged; Sarcosine; Single-Blind Method; Vegetarians; Vitamin B 12

2017
The Effect of Lean-Seafood and Non-Seafood Diets on Fecal Metabolites and Gut Microbiome: Results from a Randomized Crossover Intervention Study.
    Molecular nutrition & food research, 2019, Volume: 63, Issue:1

    Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Cross-Over Studies; Diet; Feces; Female; Gastrointestinal Microbiome; Humans; Male; Metabolome; Methylamines; Middle Aged; Risk Factors; Seafood

2019
Effects of Probiotic Supplementation on Trimethylamine-N-Oxide Plasma Levels in Hemodialysis Patients: a Pilot Study.
    Probiotics and antimicrobial proteins, 2019, Volume: 11, Issue:2

    Topics: Adult; Aged; Bifidobacterium longum; Dietary Supplements; Double-Blind Method; Female; Humans; Lactobacillus acidophilus; Male; Methylamines; Middle Aged; Pilot Projects; Probiotics; Renal Dialysis; Renal Insufficiency, Chronic; Streptococcus thermophilus

2019
Impact of short-term flavanol supplementation on fasting plasma trimethylamine N-oxide concentrations in obese adults.
    Food & function, 2018, Oct-17, Volume: 9, Issue:10

    Topics: Adult; Body Mass Index; Chocolate; Fasting; Female; Flavonoids; Humans; Male; Methylamines; Middle Aged; Obesity; Sex Factors; Tea; Young Adult

2018
Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential.
    Circulation research, 2018, 10-26, Volume: 123, Issue:10

    Topics: Adult; Animals; Bacterial Proteins; Choline; Clostridium; Fecal Microbiota Transplantation; Female; Gastrointestinal Microbiome; Humans; Lyases; Male; Methylamines; Mice; Mice, Inbred C57BL; Middle Aged; Platelet Activation; Thrombosis

2018
l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans.
    The Journal of clinical investigation, 2019, 01-02, Volume: 129, Issue:1

    Topics: Animals; Atherosclerosis; Betaine; Carnitine; Clostridiales; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Mice; Pilot Projects; Vegans

2019
Effects of probiotic supplementation on serum trimethylamine-N-oxide level and gut microbiota composition in young males: a double-blinded randomized controlled trial.
    European journal of nutrition, 2021, Volume: 60, Issue:2

    Topics: Adult; Chromatography, Liquid; Gastrointestinal Microbiome; Humans; Male; Methylamines; Oxides; Probiotics; RNA, Ribosomal, 16S; Tandem Mass Spectrometry; Young Adult

2021
In older women, a high-protein diet including animal-sourced foods did not impact serum levels and urinary excretion of trimethylamine-N-oxide.
    Nutrition research (New York, N.Y.), 2020, Volume: 78

    Topics: Aged; Carnitine; Clostridiales; Cresols; Cross-Over Studies; Diet, High-Protein; Feces; Female; Gastrointestinal Microbiome; Glutamine; Humans; Indican; Meat; Methylamines; Prebiotics; Probiotics; Sulfuric Acid Esters; Synbiotics

2020
Evaluation of an 8-Week Vegan Diet on Plasma Trimethylamine-N-Oxide and Postchallenge Glucose in Adults with Dysglycemia or Obesity.
    The Journal of nutrition, 2021, 07-01, Volume: 151, Issue:7

    Topics: Adult; Diet, Vegan; Female; Glucose; Humans; Male; Methylamines; Obesity; Oxides; Prospective Studies

2021
Effects of Lean Pork on Microbiota and Microbial-Metabolite Trimethylamine-N-Oxide: A Randomized Controlled Non-Inferiority Feeding Trial Based on the Dietary Guidelines for Americans.
    Molecular nutrition & food research, 2022, Volume: 66, Issue:9

    Topics: Animals; Choline; Gastrointestinal Microbiome; Humans; Methylamines; Microbiota; Nutrition Policy; Oxides; Pork Meat; Poultry; Red Meat; Swine

2022
The Effect of Inulin-Type Fructans on Plasma Trimethylamine N-Oxide Levels in Peritoneal Dialysis Patients: A Randomized Crossover Trial.
    Molecular nutrition & food research, 2023, Volume: 67, Issue:9

    Topics: Choline; Cross-Over Studies; Fructans; Humans; Inulin; Methylamines; Peritoneal Dialysis

2023
A water-soluble tomato extract rich in secondary plant metabolites lowers trimethylamine-n-oxide and modulates gut microbiota: a randomized, double-blind, placebo-controlled cross-over study in overweight and obese adults.
    The Journal of nutrition, 2023, Volume: 153, Issue:1

    Topics: Adult; Cross-Over Studies; Gastrointestinal Microbiome; Humans; Methylamines; Obesity; Overweight; Oxides; Solanum lycopersicum

2023
Plasma Trimethylamine-
    Journal of the American Heart Association, 2023, 08-15, Volume: 12, Issue:16

    Topics: Aged; Atherosclerosis; Female; Humans; Ischemic Stroke; Methylamines; Oxides; Prospective Studies; Risk Factors; Stroke; United States

2023

Other Studies

186 other study(ies) available for trimethylamine and trimethyloxamine

ArticleYear
Hepatotoxicity and hepatocarcinogenicity in rats fed squid with or without exogenous nitrite.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1992, Volume: 30, Issue:8

    Topics: Animals; Carcinoma, Hepatocellular; Decapodiformes; Diet; Dimethylamines; Liver; Liver Neoplasms, Experimental; Methylamines; Nitrites; Rats; Rats, Sprague-Dawley; Survival Rate

1992
The exogenous origin of trimethylamine in the mouse.
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:2

    Topics: Animals; Germ-Free Life; Male; Methylamines; Mice; Mice, Inbred Strains; Neomycin; Reference Values

1992
Poisonings from flesh of the Greenland shark Somniosus microcephalus may be due to trimethylamine.
    Toxicon : official journal of the International Society on Toxinology, 1991, Volume: 29, Issue:10

    Topics: Animals; Cooking; Diaphragm; Freezing; Guinea Pigs; Ileum; In Vitro Techniques; Magnetic Resonance Spectroscopy; Meat; Methylamines; Muscle Contraction; Muscle, Smooth; Neuromuscular Depolarizing Agents; Rats; Sharks

1991
The identification of trimethylamine excess in man: quantitative analysis and biochemical origins.
    Analytical biochemistry, 1991, Aug-15, Volume: 197, Issue:1

    Topics: Chromatography, Gas; Female; Humans; Male; Methylamines; Odorants; Reference Values

1991
A microbial biosensor for trimethylamine using Pseudomonas aminovorans cells.
    Biosensors & bioelectronics, 1991, Volume: 6, Issue:2

    Topics: Animals; Biosensing Techniques; Fishes; Food Analysis; Methylamines; Oxygen Consumption; Pseudomonas

1991
Determination of aliphatic amines by gas and high-performance liquid chromatography.
    Journal of chromatography, 1990, May-16, Volume: 507

    Topics: Amines; Chromatography, Gas; Chromatography, High Pressure Liquid; Methylamines

1990
The measurement of dimethylamine, trimethylamine, and trimethylamine N-oxide using capillary gas chromatography-mass spectrometry.
    Analytical biochemistry, 1990, Volume: 187, Issue:2

    Topics: Animals; Dimethylamines; Fishes; Gas Chromatography-Mass Spectrometry; Humans; Kidney; Kinetics; Liver; Male; Methylamines; Rats; Rats, Inbred Strains

1990
Trimethylaminuria: the detection of carriers using a trimethylamine load test.
    Journal of inherited metabolic disease, 1989, Volume: 12, Issue:1

    Topics: Administration, Oral; Adult; Genetic Carrier Screening; Humans; Male; Metabolism, Inborn Errors; Methylamines; Middle Aged

1989
Conversion of dietary choline to trimethylamine and dimethylamine in rats: dose-response relationship.
    The Journal of nutrition, 1989, Volume: 119, Issue:5

    Topics: Animals; Choline; Diet; Dimethylamines; Dose-Response Relationship, Drug; Male; Methylamines; Rats; Rats, Inbred Strains

1989
Potentiation of ferrous sulphate and ascorbate on the microbial transformation of endogenous trimethylamine N-oxide to trimethylamine and dimethylamine in squid extracts.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1989, Volume: 27, Issue:9

    Topics: Animals; Ascorbic Acid; Bacteria; Chloramphenicol; Decapodiformes; Dimethylamines; Drug Synergism; Ferrous Compounds; Methylamines

1989
Metabolism of trimethylamines in kelp bass (Paralabrax clathratus) and marine and freshwater pink salmon (Oncorhynchus gorbuscha).
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 1988, Volume: 158, Issue:5

    Topics: Animals; Bass; Betaine; Choline; Dimethylamines; Liver; Methylamines; Muscles; Perciformes; Radioactive Tracers; Salmon; Water-Electrolyte Balance

1988
Trimethylaminuria ('fish-odour syndrome'): a study of an affected family.
    Clinical science (London, England : 1979), 1988, Volume: 74, Issue:3

    Topics: Adult; Female; Humans; Male; Metabolism, Inborn Errors; Methylamines; Syndrome

1988
The metabolism of 14C-labelled trimethylamine and its N-oxide in man.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:5

    Topics: Biotransformation; Chromatography, Thin Layer; Humans; Kinetics; Male; Mass Spectrometry; Methylamines

1987
A genetic polymorphism of the N-oxidation of trimethylamine in humans.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:5

    Topics: Adolescent; Adult; Alleles; Chromatography, Gas; Female; Genes, Recessive; Homozygote; Humans; Male; Methylamines; Middle Aged; Odorants; Oxidation-Reduction; Pedigree; Polymorphism, Genetic

1987
Disclosure of the metabolic retroversion of trimethylamine N-oxide in humans: a pharmacogenetic approach.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:6

    Topics: Adolescent; Adult; Diet; Female; Humans; Male; Methylamines; Middle Aged; Oxidation-Reduction

1987
[Effect of heat treatment on the levels of dimethylamine trimethylamine and trimethylamine-N-oxide in squids].
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1985, Volume: 84, Issue:2

    Topics: Animals; Decapodiformes; Dimethylamines; Hot Temperature; Methylamines

1985
Sources of conductance changes during bacterial reduction of trimethylamine oxide to trimethylammonium in phosphate buffer.
    Journal of general microbiology, 1985, Volume: 131, Issue:6

    Topics: Buffers; Electric Conductivity; Escherichia coli; Hydrogen-Ion Concentration; Methylamines; Oxidation-Reduction; Phosphates

1985
Thermal conversion of trimethylamine-N-oxide to trimethylamine and dimethylamine in squids.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1985, Volume: 23, Issue:6

    Topics: Animals; Decapodiformes; Dimethylamines; Food Analysis; Food Handling; Hot Temperature; Methylamines

1985
Fish odor syndrome: trimethylaminuria with milk as chief dietary factor.
    Pediatric dermatology, 1985, Volume: 3, Issue:1

    Topics: Animals; Cattle; Child; Choline; Humans; Infant; Liver; Male; Methylamines; Milk; Syndrome

1985
Chromatographic separation of choline, trimethylamine, trimethylamine oxide, and betaine from tissues of marine fish.
    Analytical biochemistry, 1984, Volume: 136, Issue:2

    Topics: Animals; Betaine; Carnitine; Choline; Chromatography, Ion Exchange; Fishes; Liver; Methylamines; Muscles; Tissue Extracts

1984
Diagnosis of a new case of trimethylaminuria using direct proton NMR spectroscopy of urine.
    Journal of inherited metabolic disease, 1995, Volume: 18, Issue:2

    Topics: Humans; Magnetic Resonance Spectroscopy; Male; Methylamines; Odorants; Oxidants

1995
The N-oxidation of trimethylamine in a Jordanian population.
    British journal of clinical pharmacology, 1995, Volume: 39, Issue:2

    Topics: Adult; Ethnicity; Female; Humans; Jordan; Male; Metabolism, Inborn Errors; Methylamines; Middle Aged; Odorants; Oxidation-Reduction

1995
Urinary excretion of methylamines in men with varying intake of fish from the Baltic Sea.
    Journal of toxicology and environmental health, 1994, Volume: 41, Issue:4

    Topics: Adult; Animals; Creatinine; Diet; Dimethylamines; Fishes; Humans; Male; Methylamines; Middle Aged; Seawater; Sweden

1994
Metabolism and excretion of methylamines in rats.
    Toxicology and applied pharmacology, 1994, Volume: 125, Issue:2

    Topics: Animals; Carbon Radioisotopes; Dimethylamines; Dimethylnitrosamine; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Male; Methylamines; Models, Biological; Rats; Rats, Sprague-Dawley; Scintillation Counting

1994
Spoilage and shelf-life of cod fillets packed in vacuum or modified atmospheres.
    International journal of food microbiology, 1993, Volume: 19, Issue:4

    Topics: Animals; Carbon Dioxide; Dimethylamines; Fishes; Food Handling; Food Microbiology; Food Preservation; Gram-Negative Bacteria; Hypoxanthine; Hypoxanthines; Methylamines; Oxidants; Vacuum

1993
Do Australian desert frogs co-accumulate counteracting solutes with urea during aestivation?
    The Journal of experimental biology, 1996, Volume: 199, Issue:Pt 8

    Topics: Animals; Anura; Australia; Betaine; Body Fluids; Chromatography, High Pressure Liquid; Estivation; Glycerylphosphorylcholine; Inositol; Methylamines; Muscles; Osmolar Concentration; Polymers; Sarcosine; Urea

1996
Fish odour syndrome: verification of carrier detection test.
    Journal of inherited metabolic disease, 1995, Volume: 18, Issue:6

    Topics: Adult; Female; Genetic Carrier Screening; Humans; Male; Metabolism, Inborn Errors; Methylamines; Odorants; Syndrome

1995
Human erythrocyte choline uptake in uraemia: the role of intracellular substrate and an investigation into the effects of haemodialysis.
    Clinical science (London, England : 1979), 1996, Volume: 91, Issue:3

    Topics: Choline; Dimethylamines; Erythrocytes; Female; Humans; Ion Transport; Magnetic Resonance Spectroscopy; Male; Methylamines; Renal Dialysis; Uremia

1996
Discontinuous distribution of N-oxidation of dietary-derived trimethylamine in a British population.
    Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:9

    Topics: Adult; Diet; Female; Humans; Male; Metabolism, Inborn Errors; Methylamines; Middle Aged; Odorants; Oxidation-Reduction; United Kingdom

1996
Trimethylamine N-oxidation in Turkish women with bacterial vaginosis.
    Pharmacogenetics, 1996, Volume: 6, Issue:5

    Topics: Adolescent; Adult; Female; Humans; Methylamines; Middle Aged; Oxidation-Reduction; Smell; Turkey; Vaginal Discharge; Vaginosis, Bacterial

1996
1H-NMR analysis of trimethylamine in urine for the diagnosis of fish-odour syndrome.
    Clinica chimica acta; international journal of clinical chemistry, 1997, Jul-25, Volume: 263, Issue:2

    Topics: Amine Oxidase (Copper-Containing); Female; Humans; Liver; Magnetic Resonance Spectroscopy; Male; Metabolism, Inborn Errors; Methylamines; Odorants; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Protons

1997
A pharmacogenetic study of trimethylaminuria in Orientals.
    Pharmacogenetics, 1997, Volume: 7, Issue:6

    Topics: Adult; Asian People; Female; Humans; Male; Metabolism, Inborn Errors; Methylamines; Middle Aged; Odorants; Pedigree; Thailand

1997
Evaluation of the role of Carnobacterium piscicola in spoilage of vacuum- and modified-atmosphere-packed cold-smoked salmon stored at 5 degrees C.
    International journal of food microbiology, 1998, Feb-17, Volume: 39, Issue:3

    Topics: Animals; Bacterial Proteins; Carbon Dioxide; Cold Temperature; Colony Count, Microbial; Electrophoresis, Polyacrylamide Gel; Evaluation Studies as Topic; Fish Products; Food Microbiology; Food Packaging; Food Preservation; Food Preservatives; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydrogen-Ion Concentration; Methylamines; Nisin; Nitrogen; Odorants; Salmon; Sodium Chloride; Vacuum

1998
[Diagnosis of "fish odor syndrome" by urine nuclear magnetic resonance proton spectrometry].
    Annales de dermatologie et de venereologie, 1998, Volume: 125, Issue:3

    Topics: Genetic Carrier Screening; Genetic Diseases, Inborn; Humans; Magnetic Resonance Spectroscopy; Methylamines; Oxidants; Reproducibility of Results; Syndrome

1998
Dimethylamine formation in the rat from various related amine precursors.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1998, Volume: 36, Issue:11

    Topics: Administration, Oral; Animals; Choline; Diet; Dimethylamines; Ethylamines; Male; Methylamines; Oxidants; Propanols; Rats; Rats, Wistar

1998
Measurement of trimethylamine and trimethylamine N-oxide independently in urine by fast atom bombardment mass spectrometry.
    Analytical biochemistry, 1999, Dec-15, Volume: 276, Issue:2

    Topics: Case-Control Studies; Female; Humans; Male; Metabolism, Inborn Errors; Methylamines; Reference Values; Spectrometry, Mass, Fast Atom Bombardment

1999
Biochemical and molecular studies in mild flavin monooxygenase 3 deficiency.
    Journal of inherited metabolic disease, 2000, Volume: 23, Issue:4

    Topics: Alleles; Child; Child, Preschool; Heterozygote; Humans; Infant; Methylamines; Odorants; Oxygenases

2000
Distribution of the N-oxidation of dietary-derived trimethylamine in a male Chinese population.
    Pharmacogenetics, 2000, Volume: 10, Issue:9

    Topics: Adolescent; Adult; Asian People; Diet; Hong Kong; Humans; Male; Methylamines; Middle Aged; Oxygenases; Racial Groups

2000
Fish odour syndrome with features of both primary and secondary trimethylaminuria.
    Clinical and experimental dermatology, 2003, Volume: 28, Issue:2

    Topics: Biomarkers; Female; Humans; Metabolism, Inborn Errors; Methylamines; Middle Aged; Odorants

2003
[Effect of thermal treatments on the chemical characteristics of mora crab meat (Homalaspis plana)].
    Archivos latinoamericanos de nutricion, 2003, Volume: 53, Issue:1

    Topics: Amines; Animals; Brachyura; Hot Temperature; Hydrogen-Ion Concentration; Meat; Methylamines; Muscles; Nitrogen Compounds; Time Factors

2003
Urinary excretion of trimethylamine and trimethylamine oxide following trimethylamine-administration to normals and to patients with liver disease.
    Acta medica Scandinavica, 1956, Feb-29, Volume: 153, Issue:6

    Topics: Amines; Body Fluids; Humans; Liver Diseases; Liver Function Tests; Methylamines; Urine

1956
The non-enzymic reduction of trimethylamine oxide to trimethylamine, dimethylamine, and formaldehyde.
    Canadian journal of biochemistry and physiology, 1956, Volume: 34, Issue:6

    Topics: Amines; Cysteine; Dimethylamines; Formaldehyde; Humans; Iron; Methylamines

1956
Effect of trimethylamine and its homologues on renal conservation of trimethylamine oxide by the spiny dogfish, Squalus acanthias.
    The American journal of physiology, 1959, Volume: 196, Issue:1

    Topics: Amines; Animals; Kidney; Methylamines; Squalus acanthias

1959
The biosynthesis of trimethylamine-N-oxide.
    Biochimica et biophysica acta, 1960, Jul-15, Volume: 41

    Topics: Amines; Methylamines; Oxides

1960
The biosynthesis of trimethylamine-N-oxide.
    The Journal of biological chemistry, 1962, Volume: 237

    Topics: Amines; Methylamines; Oxides

1962
[Trimethylamine excretion in rabbits after the administration of N-14 and N-15-labeled-trimethylamine and trimethylamine oxide].
    Acta biologica et medica Germanica, 1962, Volume: 9

    Topics: Amines; Animals; Body Fluids; Methylamines; Rabbits

1962
A comparative study of trimethylamine-N-oxide biosynthesis.
    Biochimica et biophysica acta, 1963, Apr-02, Volume: 71

    Topics: Amines; Methylamines; Oxides

1963
[TRIMETHYLAMINE AND TRIMETHYLAMINE OXIDE IN THE URINE AFTER THE ADMINISTRATION OF N-14- AND N-15-(-) CARNITINE].
    Acta biologica et medica Germanica, 1963, Volume: 11

    Topics: Amines; Body Fluids; Carnitine; Folic Acid; Humans; Hyperthyroidism; Male; Methylamines; Nitrogen; Prostatic Neoplasms; Radioisotopes; Urine; Vitamin B Complex

1963
Changes in some nitrogenous compounds in the blood and tissues of freshwater pikeperch (Sander lucioperca) during salinity acclimation.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2004, Volume: 138, Issue:1

    Topics: Adaptation, Physiological; Animals; Fresh Water; Methylamines; Muscles; Ninhydrin; Nitrogen Compounds; Perciformes; Quaternary Ammonium Compounds; Sodium Chloride

2004
Quantifying trimethylamine and trimethylamine-N-oxide in human plasma: interference from endogenous quaternary ammonium compounds.
    Analytical biochemistry, 2004, Nov-15, Volume: 334, Issue:2

    Topics: Artifacts; Gas Chromatography-Mass Spectrometry; Humans; Hydroxides; Methylamines; Molecular Structure; Potassium Compounds; Quaternary Ammonium Compounds

2004
Diagnosis of suspected trimethylaminuria by NMR spectroscopy.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 351, Issue:1-2

    Topics: Adult; Amines; Animals; Choline; Diet; Dogfish; Humans; Magnetic Resonance Spectroscopy; Male; Metabolism, Inborn Errors; Methylamines; Odorants; Oxidation-Reduction; Reference Standards; Solutions

2005
Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:5

    Topics: Adult; Biomarkers; Case-Control Studies; Disease Progression; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic; Kidney Function Tests; Male; Methylamines; Middle Aged; Probability; Reference Values; Renal Dialysis; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index

2006
Short-chain aliphatic amines in human urine: a mathematical examination of metabolic interrelationships.
    Metabolism: clinical and experimental, 2007, Volume: 56, Issue:1

    Topics: Adult; Amines; Chromatography, Gas; Dimethylamines; Ethylamines; Female; Humans; Male; Methylamines; Middle Aged; Principal Component Analysis

2007
Rapid screening assay of trimethylaminuria in urine with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2007, Volume: 21, Issue:12

    Topics: Child, Preschool; Female; Humans; Infant; Metabolism, Inborn Errors; Methylamines; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2007
A flow injection electrospray ionization tandem mass spectrometric method for the simultaneous measurement of trimethylamine and trimethylamine N-oxide in urine.
    Journal of mass spectrometry : JMS, 2008, Volume: 43, Issue:4

    Topics: Humans; Metabolism, Inborn Errors; Methylamines; Odorants; Spectrometry, Mass, Electrospray Ionization

2008
Simultaneous determination of dimethylamine, trimethylamine and trimethylamine-n-oxide in aquatic products extracts by ion chromatography with non-suppressed conductivity detection.
    Journal of chromatography. A, 2009, Jul-31, Volume: 1216, Issue:31

    Topics: Chromatography, Ion Exchange; Dimethylamines; Electric Conductivity; Linear Models; Methylamines; Potassium; Quaternary Ammonium Compounds; Reproducibility of Results; Seafood; Sensitivity and Specificity; Sodium; Trichloroacetic Acid

2009
Bonitos with low content of malodorous trimethylamine as palliative care for self-reported Japanese trimethylaminuria subjects.
    Drug metabolism and pharmacokinetics, 2009, Volume: 24, Issue:6

    Topics: Amino Acid Metabolism, Inborn Errors; Asian People; Calcium Phosphates; Genetics, Population; Humans; Methylamines; Palliative Care; Pedigree; Silicon Dioxide; Volunteers

2009
Pseudomonas putida A ATCC 12633 oxidizes trimethylamine aerobically via two different pathways.
    Archives of microbiology, 2010, Volume: 192, Issue:6

    Topics: Aerobiosis; Dimethylamines; Kinetics; Methylamines; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Oxygenases; Pseudomonas putida; Trimethyl Ammonium Compounds

2010
Measurement of urinary trimethylamine and trimethylamime oxide by direct infusion electrospray quadrupole time-of-flight mass spectrometry.
    Analytical biochemistry, 2010, Nov-01, Volume: 406, Issue:1

    Topics: Humans; Methylamines; Spectrometry, Mass, Electrospray Ionization; Time Factors; Urinalysis

2010
Dynamic metabolic response of mice to acute mequindox exposure.
    Journal of proteome research, 2011, Nov-04, Volume: 10, Issue:11

    Topics: Amino Acids; Animals; Anti-Bacterial Agents; Blood Glucose; Citric Acid Cycle; Female; Glycine; Hippurates; Liver; Metabolome; Methylamines; Mice; Principal Component Analysis; Quinoxalines

2011
My child has smelly urine.
    Pediatric nephrology (Berlin, Germany), 2012, Volume: 27, Issue:7

    Topics: Adolescent; Age of Onset; Child; Diet Therapy; Humans; Male; Methylamines; Odorants; Urine

2012
Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation.
    Cell metabolism, 2013, Jan-08, Volume: 17, Issue:1

    Topics: Androgens; Animals; Atherosclerosis; Base Sequence; Bile Acids and Salts; Choline; Diet; Down-Regulation; Female; Gene Silencing; HEK293 Cells; Humans; Male; Methylamines; Mice; Mice, Knockout; Oxygenases; Polymorphism, Single Nucleotide; Receptors, Cytoplasmic and Nuclear; Sex Factors

2013
Risk factors for cardiovascular disease: a cautionary tale of diet-microbiome interactions.
    Journal of the American College of Nutrition, 2013, Volume: 32, Issue:2

    Topics: Cardiovascular Diseases; Carnitine; Choline; Diet; Gastrointestinal Tract; Humans; Methylamines; Microbiota; Risk Factors

2013
Trimethylamine oxide, dimethylamine, trimethylamine and formaldehyde levels in main traded fish species in Hong Kong.
    Food additives & contaminants. Part B, Surveillance, 2009, Volume: 2, Issue:1

    Topics: Animals; Carcinogens; Dimethylamines; Fishes; Food Analysis; Food Contamination; Formaldehyde; Hong Kong; Humans; Methylamines

2009
Trimethylamine and trimethylamine N-oxide are supplementary energy sources for a marine heterotrophic bacterium: implications for marine carbon and nitrogen cycling.
    The ISME journal, 2015, Volume: 9, Issue:3

    Topics: Carbon; Carbon Cycle; Glucose; Heterotrophic Processes; Methylamines; Nitrogen; Nitrogen Cycle; Oxidation-Reduction; Rhodobacteraceae; Seawater

2015
Fish odor syndrome (trimethylaminuria) supporting the possible FMO3 down expression in childhood: a case report.
    Journal of medical case reports, 2014, Oct-06, Volume: 8

    Topics: Biomarkers; Child; Down-Regulation; Female; Genetic Markers; Humans; Metabolism, Inborn Errors; Methylamines; Oxygenases; Polymorphism, Single Nucleotide

2014
Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis.
    Journal of lipid research, 2015, Volume: 56, Issue:1

    Topics: Animals; Atherosclerosis; Bile Acids and Salts; Cell Line, Tumor; Diet, Western; DNA-Binding Proteins; Feces; Female; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; Gene Knockout Techniques; Glucose; Homeostasis; Humans; Insulin; Intestinal Mucosa; Kruppel-Like Transcription Factors; Lipid Metabolism; Lipogenesis; Lipoproteins; Liver; Methylamines; Mice; Oxygenases; PPAR alpha; Receptors, LDL; Transcription Factors

2015
Transmission of atherosclerosis susceptibility with gut microbial transplantation.
    The Journal of biological chemistry, 2015, Feb-27, Volume: 290, Issue:9

    Topics: Animals; Aorta; Atherosclerosis; Cecum; Choline; Diet; Disease Susceptibility; Female; Gastrointestinal Tract; Host-Pathogen Interactions; Humans; Male; Methylamines; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred Strains; Mice, Knockout; Mice, Transgenic; Microbiota; Species Specificity

2015
Plaque burden in HIV-infected patients is associated with serum intestinal microbiota-generated trimethylamine.
    AIDS (London, England), 2015, Feb-20, Volume: 29, Issue:4

    Topics: Choline; Coronary Artery Disease; Dysbiosis; Female; HIV Infections; Humans; Intestinal Diseases; Male; Methylamines; Middle Aged; Plaque, Atherosclerotic; Prognosis; Risk Assessment; Risk Factors

2015
Fish Malodour syndrome in a child.
    BMJ case reports, 2015, Apr-13, Volume: 2015

    Topics: Child, Preschool; Diagnosis, Differential; Diet Therapy; Female; Humans; Hygiene; Metabolism, Inborn Errors; Methylamines; Mutation; Oxygenases; Polymorphism, Genetic

2015
Microbiota-Dependent Marker TMAO Is Elevated in Silent Ischemia but Is Not Associated With First-Time Myocardial Infarction in HIV Infection.
    Journal of acquired immune deficiency syndromes (1999), 2016, Feb-01, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Aged; Biomarkers; Case-Control Studies; Cohort Studies; Coronary Artery Disease; Cross-Sectional Studies; Female; HIV Infections; Humans; Ischemia; Male; Methylamines; Microbiota; Middle Aged; Myocardial Infarction; Plaque, Atherosclerotic; Risk Factors; Young Adult

2016
Plasma Concentrations of Trimethylamine-N-oxide Are Directly Associated with Dairy Food Consumption and Low-Grade Inflammation in a German Adult Population.
    The Journal of nutrition, 2016, Volume: 146, Issue:2

    Topics: Adult; Animals; Betaine; C-Reactive Protein; Choline; Dairy Products; Diet; Diet Surveys; Feeding Behavior; Female; Germany; Humans; Inflammation; Interleukin-6; Male; Methylamines; Middle Aged; Milk; Receptors, Tumor Necrosis Factor, Type I; Tumor Necrosis Factor-alpha

2016
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:3

    Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Gastrointestinal Microbiome; Humans; Lipoproteins, HDL; Male; Methylamines; Methylation; Middle Aged; Phosphatidylcholines; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors

2016
Resveratrol Attenuates Trimethylamine-N-Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota.
    mBio, 2016, Apr-05, Volume: 7, Issue:2

    Topics: Animals; Atherosclerosis; Bacteria; Bile Acids and Salts; Cholesterol 7-alpha-Hydroxylase; Female; Gastrointestinal Microbiome; Humans; Liver; Methylamines; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes

2016
Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors.
    The Journal of nutritional biochemistry, 2016, Volume: 33

    Topics: Administration, Oral; Animals; Atherosclerosis; Biomarkers; Choline; Deuterium; Dietary Fats; Environmental Pollutants; Enzyme Induction; Food-Drug Interactions; Liver; Male; Methylamines; Mice, Inbred C57BL; Oxygenases; Phosphatidylcholines; Polychlorinated Biphenyls; Random Allocation; Up-Regulation

2016
Spoilage potential characterization of Shewanella and Pseudomonas isolated from spoiled large yellow croaker (Pseudosciaena crocea).
    Letters in applied microbiology, 2017, Volume: 64, Issue:1

    Topics: Animals; DNA Gyrase; Food Contamination; Food Microbiology; Methylamines; Perciformes; Phylogeny; Pseudomonas; RNA, Ribosomal, 16S; Shewanella

2017
Determination of trimethylamine, trimethylamine N-oxide, and taurine in human plasma and urine by UHPLC-MS/MS technique.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016, Dec-01, Volume: 1038

    Topics: Aged; Chromatography, High Pressure Liquid; Humans; Limit of Detection; Methylamines; Middle Aged; Tandem Mass Spectrometry; Taurine

2016
Dietary, anthropometric, and biochemical factors influencing plasma choline, carnitine, trimethylamine, and trimethylamine-N-oxide concentrations.
    International journal of food sciences and nutrition, 2017, Volume: 68, Issue:4

    Topics: Aged; Body Size; Carnitine; Choline; Diet; Female; Humans; Methylamines; Middle Aged

2017
Simultaneous determination of trimethylamine and trimethylamine N-oxide in mouse plasma samples by hydrophilic interaction liquid chromatography coupled to tandem mass spectrometry.
    Journal of separation science, 2017, Volume: 40, Issue:3

    Topics: Animals; Blood Chemical Analysis; Chromatography, Liquid; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Methylamines; Mice; Reproducibility of Results; Tandem Mass Spectrometry

2017
Structural mechanism for bacterial oxidation of oceanic trimethylamine into trimethylamine N-oxide.
    Molecular microbiology, 2017, Volume: 103, Issue:6

    Topics: Amino Acid Sequence; Carbon Cycle; Catalysis; Cloning, Molecular; Crystallography, X-Ray; Flavins; Methylamines; NADP; Nitrogen Cycle; Oxidation-Reduction; Oxygenases; Protein Structure, Quaternary; Rhodobacteraceae; Sequence Alignment

2017
Blood Trimethylamine-N-Oxide Originates from Microbiota Mediated Breakdown of Phosphatidylcholine and Absorption from Small Intestine.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Aged; Cardiovascular Diseases; Gas Chromatography-Mass Spectrometry; Humans; Intestine, Small; Male; Methylamines; Microbiota; Mixed Function Oxygenases; Oxides; Phosphatidylcholines; Rifamycins; Rifaximin; Risk Factors; Spectrometry, Mass, Electrospray Ionization

2017
What Are Missing Parts in the Research Story of Trimethylamine-N-oxide (TMAO)?
    Journal of agricultural and food chemistry, 2017, Jul-05, Volume: 65, Issue:26

    Topics: Animals; Cardiovascular Diseases; Cattle; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Intestines; Methylamines; Red Meat

2017
Human plasma and urinary metabolic profiles of trimethylamine and trimethylamine N-oxide extrapolated using a simple physiologically based pharmacokinetic model.
    The Journal of toxicological sciences, 2017, Volume: 42, Issue:4

    Topics: Administration, Oral; Animals; Carnitine; Humans; In Vitro Techniques; Kidney; Male; Methylamines; Microsomes, Liver; Models, Biological; Rats; Rats, Sprague-Dawley; Risk Assessment

2017
[Research progress of trimethylamine-N-oxide in the pathogenesis of atherosclerosis].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2017, Aug-28, Volume: 42, Issue:8

    Topics: Atherosclerosis; Humans; Methylamines; Oxides

2017
Soluble Dietary Fiber Reduces Trimethylamine Metabolism via Gut Microbiota and Co-Regulates Host AMPK Pathways.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:12

    Topics: AMP-Activated Protein Kinases; Animals; Cholesterol; Diet; Dietary Fiber; Energy Intake; Fatty Acids, Volatile; Fermented Foods; Gastrointestinal Microbiome; Intestinal Mucosa; Lipids; Metagenome; Methylamines; Mice, Inbred C57BL; Red Meat; Solubility

2017
Effects of Trimethylamine-N-oxide on the Conformation of Peptides and its Implications for Proteins.
    Physical review letters, 2017, Sep-08, Volume: 119, Issue:10

    Topics: Hydrophobic and Hydrophilic Interactions; Methylamines; Molecular Conformation; Molecular Dynamics Simulation; Peptides; Proteins

2017
A simple dilute and shoot approach incorporated with pentafluorophenyl (PFP) column based LC-MS/MS assay for the simultaneous determination of trimethylamine N-oxide and trimethylamine in spot urine samples with high throughput.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017, Nov-01, Volume: 1067

    Topics: Adult; Chromatography, Liquid; Female; Fluorobenzenes; High-Throughput Screening Assays; Humans; Limit of Detection; Linear Models; Male; Methylamines; Middle Aged; Phenols; Reproducibility of Results; Tandem Mass Spectrometry

2017
CntA oxygenase substrate profile comparison and oxygen dependency of TMA production in Providencia rettgeri.
    Journal of basic microbiology, 2018, Volume: 58, Issue:1

    Topics: Carnitine; Humans; Methylamines; Microbiota; Oxidation-Reduction; Oxygen; Oxygenases; Providencia; Substrate Specificity

2018
Inactivation mechanism of N61S mutant of human FMO3 towards trimethylamine.
    Scientific reports, 2017, 11-07, Volume: 7, Issue:1

    Topics: Computer Simulation; Humans; In Vitro Techniques; Metabolism, Inborn Errors; Methylamines; Mutation; Oxidation-Reduction; Oxygenases

2017
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk.
    JCI insight, 2018, 03-22, Volume: 3, Issue:6

    Topics: Aged; Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Cholesterol; Choline; Disease Models, Animal; Feces; Female; Gastrointestinal Microbiome; Genome-Wide Association Study; Humans; Lysine; Male; Metabolomics; Methylamines; Mice; Mice, Inbred C57BL; Middle Aged; Nutrients; Risk Factors; Thrombosis

2018
Human plasma concentrations of trimethylamine N-oxide extrapolated using pharmacokinetic modeling based on metabolic profiles of deuterium-labeled trimethylamine in humanized-liver mice.
    The Journal of toxicological sciences, 2018, Volume: 43, Issue:6

    Topics: Administration, Oral; Animals; Atherosclerosis; Deuterium; Hepatocytes; Humans; Methylamines; Mice; Microsomes, Liver; Models, Animal; Models, Biological; Rats; Risk Assessment

2018
Simultaneous HS-SPME GC-MS determination of short chain fatty acids, trimethylamine and trimethylamine N-oxide for gut microbiota metabolic profile.
    Talanta, 2018, Nov-01, Volume: 189

    Topics: Fatty Acids, Volatile; Gas Chromatography-Mass Spectrometry; Gastrointestinal Microbiome; Humans; Metabolomics; Methylamines; Reproducibility of Results; Solid Phase Microextraction; Time Factors

2018
Guggulsterone, a farnesoid X receptor antagonist lowers plasma trimethylamine-
    Human & experimental toxicology, 2019, Volume: 38, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; Cardiotonic Agents; Choline; Clostridium; Diet; Escherichia; Hypolipidemic Agents; Kidney; Lipid Peroxidation; Liver; Methylamines; Myocardium; Pregnenediones; Rats, Wistar; Receptors, Cytoplasmic and Nuclear

2019
Bugs in the system.
    Thrombosis research, 2019, Volume: 174

    Topics: Gastrointestinal Microbiome; Humans; Methylamines; Oxides; Venous Thromboembolism

2019
Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report.
    Arteriosclerosis, thrombosis, and vascular biology, 2019, Volume: 39, Issue:6

    Topics: Animals; Atherosclerosis; Choline; Disease Models, Animal; Lipid Metabolism; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxygenases; Polymerase Chain Reaction; Random Allocation; Reference Values; Thrombosis

2019
A direct time-based ITC approach for substrate turnover measurements demonstrated on human FMO3.
    Chemical communications (Cambridge, England), 2019, May-28, Volume: 55, Issue:44

    Topics: Calorimetry; Humans; Kinetics; Methylamines; Oxygenases; Substrate Specificity

2019
Effect of vacuum impregnated fish gelatin and grape seed extract on metabolite profiles of tilapia (Oreochromis niloticus) fillets during storage.
    Food chemistry, 2019, Sep-30, Volume: 293

    Topics: Animals; Choline; Cichlids; Fish Products; Food Storage; Gelatin; Grape Seed Extract; Histidine; Magnetic Resonance Spectroscopy; Methylamines; Multivariate Analysis; Vacuum

2019
FMO3 and its metabolite TMAO contribute to the formation of gallstones.
    Biochimica et biophysica acta. Molecular basis of disease, 2019, 10-01, Volume: 1865, Issue:10

    Topics: Animals; Atherosclerosis; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Cholesterol; Diet; Disease Models, Animal; Female; Gallstones; Gastrointestinal Microbiome; Gene Expression Regulation; Humans; Lipoproteins; Liver; Male; Methylamines; Mice, Inbred AKR; Mice, Inbred C57BL; Oxygenases; RNA, Messenger

2019
Oolong Tea Extract and Citrus Peel Polymethoxyflavones Reduce Transformation of l-Carnitine to Trimethylamine-
    Journal of agricultural and food chemistry, 2019, Jul-17, Volume: 67, Issue:28

    Topics: Animals; Atherosclerosis; Bacteria; Biotransformation; Camellia sinensis; Carnitine; Citrus; Female; Flavones; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Methylamines; Mice; Mice, Inbred C57BL; Plant Extracts; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2019
Targeting on Gut Microbial Metabolite Trimethylamine-N-Oxide and Short-Chain Fatty Acid to Prevent Maternal High-Fructose-Diet-Induced Developmental Programming of Hypertension in Adult Male Offspring.
    Molecular nutrition & food research, 2019, Volume: 63, Issue:18

    Topics: Acetates; Animals; Blood Pressure; Dietary Supplements; Fatty Acids, Volatile; Female; Fructose; Gastrointestinal Microbiome; Hexanols; Hypertension; Magnesium Compounds; Male; Methylamines; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley

2019
Gut microbe-derived metabolite trimethylamine N-oxide accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis.
    Journal of molecular and cellular cardiology, 2019, Volume: 134

    Topics: Animals; Cell Differentiation; Collagen Type I; Disease Models, Animal; Fibroblasts; Fibrosis; Gastrointestinal Microbiome; Male; Methylamines; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Myofibroblasts; Smad3 Protein; Transforming Growth Factor beta1

2019
Trimethylamine But Not Trimethylamine Oxide Increases With Age in Rat Plasma and Affects Smooth Muscle Cells Viability.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2020, 06-18, Volume: 75, Issue:7

    Topics: Age Factors; Animals; Cardiovascular Diseases; Cell Culture Techniques; Cell Survival; Gastrointestinal Microbiome; Humans; Male; Methylamines; Myocytes, Smooth Muscle; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Risk Factors

2020
TMA, A Forgotten Uremic Toxin, but Not TMAO, Is Involved in Cardiovascular Pathology.
    Toxins, 2019, 08-26, Volume: 11, Issue:9

    Topics: Adult; Aged; Animals; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Cell Survival; Cells, Cultured; Female; Glomerular Filtration Rate; Healthy Volunteers; Humans; Male; Methylamines; Myocytes, Cardiac; Rats

2019
TMA (trimethylamine), but not its oxide TMAO (trimethylamine-oxide), exerts haemodynamic effects: implications for interpretation of cardiovascular actions of gut microbiome.
    Cardiovascular research, 2019, Dec-01, Volume: 115, Issue:14

    Topics: Animals; Arterial Pressure; Bacteria; Gastrointestinal Microbiome; Methylamines; Rats, Sprague-Dawley; Signal Transduction; Time Factors

2019
A faster and simpler UPLC-MS/MS method for the simultaneous determination of trimethylamine N-oxide, trimethylamine and dimethylamine in different types of biological samples.
    Food & function, 2019, Oct-16, Volume: 10, Issue:10

    Topics: Animals; Chromatography, High Pressure Liquid; Dimethylamines; Male; Methylamines; Mice; Tandem Mass Spectrometry

2019
High concentrations of trimethylamines in slime glands inhibit skein unraveling in Pacific hagfish.
    The Journal of experimental biology, 2019, 11-22, Volume: 222, Issue:Pt 22

    Topics: Adhesives; Animals; Betaine; Hagfishes; Methylamines; Mucus; Sarcosine; Seawater

2019
Elevation of Trimethylamine-N-Oxide in Chronic Kidney Disease: Contribution of Decreased Glomerular Filtration Rate.
    Toxins, 2019, 11-01, Volume: 11, Issue:11

    Topics: Adult; Betaine; Choline; Creatinine; Female; Gastrointestinal Microbiome; Glomerular Filtration Rate; Humans; Male; Metabolic Clearance Rate; Methylamines; Middle Aged; Prospective Studies; Renal Dialysis; Renal Insufficiency, Chronic

2019
Metabolic Activation of Flavin Monooxygenase-mediated Trimethylamine-N-Oxide Formation in Experimental Kidney Disease.
    Scientific reports, 2019, 11-04, Volume: 9, Issue:1

    Topics: Activation, Metabolic; Animals; Blood Urea Nitrogen; Creatinine; Cytochrome P-450 CYP1A2; Disease Models, Animal; Kinetics; Male; Methylamines; Mixed Function Oxygenases; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Substrate Specificity

2019
Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels.
    Journal of the neurological sciences, 2020, Feb-15, Volume: 409

    Topics: Aged; Amyotrophic Lateral Sclerosis; Biomarkers; Female; Formaldehyde; Humans; Male; Methylamines; Middle Aged; Queensland

2020
Trimethylamine-N-oxide is present in human follicular fluid and is a negative predictor of embryo quality.
    Human reproduction (Oxford, England), 2020, 01-01, Volume: 35, Issue:1

    Topics: Cross-Sectional Studies; Female; Fertilization in Vitro; Follicular Fluid; Humans; Methylamines; Netherlands; Oxides; Pregnancy

2020
[Trimethylamine-N-oxide and cardiovascular events in chronic kidney disease].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2019, Nov-28, Volume: 44, Issue:11

    Topics: Biomarkers; Cardiovascular Diseases; Humans; Methylamines; Oxides; Renal Insufficiency, Chronic

2019
Trimethylamine, a Toxic Precursor of Trimethylamine Oxide, Lost in Medical Databases.
    The Journal of nutrition, 2020, 02-01, Volume: 150, Issue:2

    Topics: Databases, Factual; Humans; Methylamines

2020
Baicalin ameliorates neuropathology in repeated cerebral ischemia-reperfusion injury model mice by remodeling the gut microbiota.
    Aging, 2020, 02-21, Volume: 12, Issue:4

    Topics: Animals; Brain; Clusterin; Cytokines; Disease Models, Animal; Flavonoids; Gastrointestinal Microbiome; Inflammation; Male; Methylamines; Mice; Neurons; Neuroprotective Agents; Reperfusion Injury

2020
Pressure, Peptides, and a Piezolyte: Structural Analysis of the Effects of Pressure and Trimethylamine-
    The journal of physical chemistry. B, 2020, 07-30, Volume: 124, Issue:30

    Topics: Hydrogen Bonding; Methylamines; Molecular Dynamics Simulation; Peptides; Urea; Water

2020
Reduction of Trimethylamine Off-Odor by Lactic Acid Bacteria Isolated from Korean Traditional Fermented Food and Their In Situ Application.
    Journal of microbiology and biotechnology, 2020, Oct-28, Volume: 30, Issue:10

    Topics: Animals; Fermented Foods; Fishes; Food Microbiology; Lactobacillales; Lactobacillus; Lactobacillus plantarum; Methylamines; Odorants; Pediococcus; Republic of Korea; Seafood

2020
TMAO: Trimethylamine-N-Oxide or Time to Minimize Intake of Animal Products?
    The Journal of clinical endocrinology and metabolism, 2020, 12-01, Volume: 105, Issue:12

    Topics: Animals; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Methylamines; Oxides; Plasma

2020
Metagenomic data-mining reveals enrichment of trimethylamine-N-oxide synthesis in gut microbiome in atrial fibrillation patients.
    BMC genomics, 2020, Jul-30, Volume: 21, Issue:1

    Topics: Atrial Fibrillation; Data Mining; Gastrointestinal Microbiome; Humans; Methylamines; Oxides

2020
Protective Effects of Black Raspberry (
    Nutrients, 2020, Aug-14, Volume: 12, Issue:8

    Topics: Animals; Anthocyanins; Cecum; Choline; Cyclooxygenase 2; Diet, High-Fat; Dietary Supplements; Eating; Female; Hepatitis; Hypercholesterolemia; Interleukin-1beta; Liver; Methylamines; NF-kappa B; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Rubus

2020
Heart Failure Disturbs Gut-Blood Barrier and Increases Plasma Trimethylamine, a Toxic Bacterial Metabolite.
    International journal of molecular sciences, 2020, Aug-26, Volume: 21, Issue:17

    Topics: Animals; Bacteria; Chromatography, High Pressure Liquid; Feces; Gastrointestinal Microbiome; Heart Failure; Male; Mass Spectrometry; Methylamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2020
Metformin decreases bacterial trimethylamine production and trimethylamine N-oxide levels in db/db mice.
    Scientific reports, 2020, 09-03, Volume: 10, Issue:1

    Topics: Animals; Gastrointestinal Microbiome; Klebsiella pneumoniae; Male; Metformin; Methylamines; Mice; Mice, Inbred Strains

2020
Determination of Trimethylamine-N-oxide by a Simple Isocratic High-Throughput Liquid-Chromatography Tandem Mass-Spectrometry Method.
    Clinical laboratory, 2020, Sep-01, Volume: 66, Issue:9

    Topics: Adult; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Methylamines; Oxides; Reproducibility of Results; Tandem Mass Spectrometry

2020
Trimethylamine N-oxygenation in cynomolgus macaques genotyped for flavin-containing monooxygenase 3 (FMO3).
    Drug metabolism and pharmacokinetics, 2020, Volume: 35, Issue:6

    Topics: Administration, Oral; Animals; Biotransformation; Genotype; Liver; Macaca fascicularis; Male; Methylamines; Microsomes, Liver; Oxidation-Reduction; Oxygenases; Pharmacogenomic Variants; Phenotype

2020
Use of Flavin-Containing Monooxygenases for Conversion of Trimethylamine in Salmon Protein Hydrolysates.
    Applied and environmental microbiology, 2020, 11-24, Volume: 86, Issue:24

    Topics: Amino Acid Sequence; Bacterial Proteins; Escherichia coli; Methylamines; Oxygenases; Phylogeny; Recombinant Proteins; Sequence Alignment

2020
Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Adult; Bacteria; Bacterial Proteins; Biomarkers; Carnitine; Common Variable Immunodeficiency; Diet; Feces; Female; Gastrointestinal Microbiome; Humans; Immunoglobulin A, Secretory; Inflammation; Lipopolysaccharides; Male; Metabolic Networks and Pathways; Methylamines; Middle Aged; Rifaximin

2020
Vascular reactivity stimulated by TMA and TMAO: Are perivascular adipose tissue and endothelium involved?
    Pharmacological research, 2021, Volume: 163

    Topics: Adipose Tissue; Animals; Aorta, Thoracic; Calcium; Calcium Channels, L-Type; Endothelium, Vascular; Liver; Male; Methylamines; Oxygenases; Rats, Sprague-Dawley

2021
Association of gut-related metabolites with outcome in acute heart failure.
    American heart journal, 2021, Volume: 234

    Topics: Acetylcarnitine; Acute Disease; Aged; Aged, 80 and over; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Heart Failure; Hospital Mortality; Humans; Male; Methylamines; Natriuretic Peptide, Brain; Risk Factors; Statistics, Nonparametric

2021
Using matrix-induced ion suppression combined with LC-MS/MS for quantification of trimethylamine-N-oxide, choline, carnitine and acetylcarnitine in dried blood spot samples.
    Analytica chimica acta, 2021, Mar-08, Volume: 1149

    Topics: Acetylcarnitine; Carnitine; Choline; Chromatography, Liquid; Dried Blood Spot Testing; Humans; Methylamines; Oxides; Reproducibility of Results; Tandem Mass Spectrometry

2021
Oxidation of trimethylamine to trimethylamine
    Science advances, 2021, Volume: 7, Issue:13

    Topics: Bacteria; Hydrostatic Pressure; Methylamines

2021
Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome.
    NPJ biofilms and microbiomes, 2021, 04-16, Volume: 7, Issue:1

    Topics: Animals; Atherosclerosis; Berberine; Choline; Diet; Disease Models, Animal; Disease Susceptibility; Dysbiosis; Gastrointestinal Microbiome; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE

2021
Trimethylamine N-oxide variation in humans: the product of a diet-microbiota interaction?
    The American journal of clinical nutrition, 2021, 06-01, Volume: 113, Issue:6

    Topics: Cardiovascular Diseases; Diet; Gastrointestinal Microbiome; Hispanic or Latino; Humans; Methylamines; Microbiota; Oxides; Public Health

2021
A surgical method for continuous intraportal infusion of gut microbial metabolites in mice.
    JCI insight, 2021, 05-10, Volume: 6, Issue:9

    Topics: Animals; Gastrointestinal Microbiome; Gene Expression; Infusions, Intravenous; Liver; Methylamines; Mice; Phenylacetates; Portal Vein; RNA-Seq; Transcriptome

2021
Circulating trimethylamine-N-oxide is associated with all-cause mortality in subjects with nonalcoholic fatty liver disease.
    Liver international : official journal of the International Association for the Study of the Liver, 2021, Volume: 41, Issue:10

    Topics: Biomarkers; Cohort Studies; Humans; Methylamines; Non-alcoholic Fatty Liver Disease; Oxides; Prospective Studies; Risk Factors

2021
Ligustrum robustum Alleviates Atherosclerosis by Decreasing Serum TMAO, Modulating Gut Microbiota, and Decreasing Bile Acid and Cholesterol Absorption in Mice.
    Molecular nutrition & food research, 2021, Volume: 65, Issue:14

    Topics: Animals; Atherosclerosis; Bile Acids and Salts; Cholesterol; Dietary Supplements; Female; Gastrointestinal Microbiome; Ligustrum; Liver; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Plant Extracts

2021
Simultaneous quantification of trimethylamine N-oxide, trimethylamine, choline, betaine, creatinine, and propionyl-, acetyl-, and L-carnitine in clinical and food samples using HILIC-LC-MS.
    Analytical and bioanalytical chemistry, 2021, Volume: 413, Issue:21

    Topics: Betaine; Carnitine; Choline; Chromatography, Liquid; Creatinine; Female; Food Analysis; Humans; Limit of Detection; Male; Methylamines; Middle Aged; Tandem Mass Spectrometry

2021
Quality consideration for the validation of urine TMA and TMAO measurement by nuclear magnetic resonance spectroscopy in Fish Odor Syndrome.
    Analytical biochemistry, 2021, 10-01, Volume: 630

    Topics: Calibration; Female; Humans; Magnetic Resonance Spectroscopy; Metabolism, Inborn Errors; Methylamines; Middle Aged; Quality Control

2021
Trimethylamine-N-Oxide and Precursors as Novel Potential Biomarkers for Anxiety Disorder.
    Laboratory medicine, 2022, Mar-07, Volume: 53, Issue:2

    Topics: Anxiety Disorders; Biomarkers; Chromatography, Liquid; Humans; Methylamines; Oxides; Tandem Mass Spectrometry

2022
Unraveling the metabolic pathway of choline-TMA-TMAO: Effects of gypenosides and implications for the therapy of TMAO related diseases.
    Pharmacological research, 2021, Volume: 173

    Topics: Animals; Brain; Choline; Feces; Female; Gastrointestinal Microbiome; Gynostemma; Lipid Metabolism; Methylamines; Mice, Inbred BALB C; Microsomes, Liver; Oxygenases; Plant Extracts; RNA, Ribosomal, 16S

2021
Rapid Detection of Gut Microbial Metabolite Trimethylamine N-Oxide for Chronic Kidney Disease Prevention.
    Biosensors, 2021, Sep-14, Volume: 11, Issue:9

    Topics: Atherosclerosis; Gastrointestinal Microbiome; Humans; Manganese Compounds; Methylamines; Oxides; Renal Insufficiency, Chronic

2021
Trimethylamine-N-oxide (TMAO) and clinical outcomes in patients with end-stage kidney disease receiving peritoneal dialysis.
    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 2022, Volume: 42, Issue:6

    Topics: Biomarkers; Cardiovascular Diseases; Humans; Kidney Failure, Chronic; Oxides; Peritoneal Dialysis; Peritonitis; Prospective Studies; Retrospective Studies; Risk Factors

2022
Changes of flavin-containing monooxygenases and trimethylamine-N-oxide may be involved in the promotion of non-alcoholic fatty liver disease by intestinal microbiota metabolite trimethylamine.
    Biochemical and biophysical research communications, 2022, 02-26, Volume: 594

    Topics: Animals; Cell Line; Endoplasmic Reticulum Chaperone BiP; Gastrointestinal Microbiome; Gene Silencing; Humans; Immunohistochemistry; Inflammation; Male; Membrane Proteins; Methylamines; Non-alcoholic Fatty Liver Disease; Oxygenases; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; X-Box Binding Protein 1

2022
Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms.
    eLife, 2022, 01-24, Volume: 11

    Topics: Animals; Choline; Circadian Rhythm; Diet, High-Fat; Enzyme Inhibitors; Gastrointestinal Microbiome; Leptin; Lyases; Male; Methylamines; Mice; Mice, Inbred C57BL; Obesity

2022
Atherosclerosis amelioration by allicin in raw garlic through gut microbiota and trimethylamine-N-oxide modulation.
    NPJ biofilms and microbiomes, 2022, 01-27, Volume: 8, Issue:1

    Topics: Animals; Atherosclerosis; Disulfides; Garlic; Gastrointestinal Microbiome; Humans; Methylamines; Mice; Mice, Inbred C57BL; Oxides; Sulfinic Acids

2022
Can Urea and Trimethylamine-
    The journal of physical chemistry. B, 2022, 02-24, Volume: 126, Issue:7

    Topics: Lipids; Methylamines; Solutions; Urea; Water

2022
Balancing the Equation: A Natural History of Trimethylamine and Trimethylamine-
    Journal of proteome research, 2022, 03-04, Volume: 21, Issue:3

    Topics: Animals; Bacteria; Methylamines; Oxides

2022
Possible correlation between high circulatory levels of trimethylamine-N-oxide and 2177G>C polymorphisms of hepatic flavin containing monooxygenase 3 in Kurdish Population with non-alcoholic fatty liver disease.
    Molecular biology reports, 2022, Volume: 49, Issue:7

    Topics: Case-Control Studies; Chromatography, Liquid; Flavins; Humans; Methylamines; Mixed Function Oxygenases; Non-alcoholic Fatty Liver Disease; Oxides; Oxygenases; Tandem Mass Spectrometry

2022
Trimethylamine-N-oxide (TMAO) versus echocardiographic, biochemical and histopathological indices of heart failure in patients with severe aortic stenosis: Rationale and design of the prospective, observational TASTE study.
    Cardiology journal, 2022, Volume: 29, Issue:4

    Topics: Aortic Valve Stenosis; Echocardiography; Heart Failure; Humans; Methylamines; Oxides; Prospective Studies; Taste

2022
Transferrin predicts trimethylamine-N-oxide levels and is a potential biomarker of cardiovascular disease.
    BMC cardiovascular disorders, 2022, 05-10, Volume: 22, Issue:1

    Topics: Biomarkers; Cardiovascular Diseases; Humans; Methylamines; Oxides; Transferrin

2022
Docosahexaenoic acid-acylated curcumin diester alleviates cisplatin-induced acute kidney injury by regulating the effect of gut microbiota on the lipopolysaccharide- and trimethylamine-
    Food & function, 2022, Jun-06, Volume: 13, Issue:11

    Topics: Acute Kidney Injury; Animals; Cisplatin; Curcumin; Docosahexaenoic Acids; Gastrointestinal Microbiome; Kidney; Lipopolysaccharides; Methylamines; Mice; NF-kappa B; Oxidative Stress; Oxides; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction

2022
N-3 polyunsaturated fatty acids block the trimethylamine-N-oxide- ACE2- TMPRSS2 cascade to inhibit the infection of human endothelial progenitor cells by SARS-CoV-2.
    The Journal of nutritional biochemistry, 2022, Volume: 109

    Topics: Angiotensin-Converting Enzyme 2; COVID-19; Docosahexaenoic Acids; Eicosapentaenoic Acid; Endothelial Progenitor Cells; Fatty Acids, Omega-3; Humans; Interleukin-6; Methylamines; MicroRNAs; NF-kappa B; Oxides; Peptidyl-Dipeptidase A; SARS-CoV-2; Serine Endopeptidases

2022
Gut-Flora-Dependent Metabolite Trimethylamine-N-Oxide Promotes Atherosclerosis-Associated Inflammation Responses by Indirect ROS Stimulation and Signaling Involving AMPK and SIRT1.
    Nutrients, 2022, Aug-15, Volume: 14, Issue:16

    Topics: AMP-Activated Protein Kinases; Animals; Atherosclerosis; Choline; Gastrointestinal Microbiome; Inflammation; Methylamines; Mice; Oxides; Reactive Oxygen Species; Sirtuin 1

2022
Associations of Diet with Urinary Trimethylamine-N-Oxide (TMAO) and Its Precursors among Free-Living 10-Year-Old Children: Data from SMBCS.
    Nutrients, 2022, Aug-19, Volume: 14, Issue:16

    Topics: Animals; Choline; Diet; Humans; Meat; Methylamines; Oxides

2022
Multiple mediation effects on association between prenatal triclosan exposure and birth outcomes.
    Environmental research, 2022, Volume: 215, Issue:Pt 1

    Topics: Acetylcarnitine; Bayes Theorem; Betaine; Choline; Cohort Studies; Estradiol; Female; Humans; Leptin; Maternal Exposure; Methylamines; Oxides; Pregnancy; Testosterone; Thyroid Hormones; Thyroxine; Triclosan

2022
Increased plasma trimethylamine-
    Food & function, 2022, Oct-03, Volume: 13, Issue:19

    Topics: Aged; Biomarkers; Blood Glucose; Cardiovascular Diseases; Cognitive Dysfunction; Heart Disease Risk Factors; Humans; Lipids; Methylamines; Middle Aged; Oxides; Risk Factors

2022
Trimethylamine-N-oxide (TMAO) mediates the crosstalk between the gut microbiota and hepatic vascular niche to alleviate liver fibrosis in nonalcoholic steatohepatitis.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Animals; Disease Models, Animal; Gastrointestinal Microbiome; Liver Cirrhosis; Methylamines; Mice; Non-alcoholic Fatty Liver Disease; Oxides

2022
Association of Choline Intake with Blood Pressure and Effects of Its Microbiota-Dependent Metabolite Trimethylamine-N-Oxide on Hypertension.
    Cardiovascular therapeutics, 2022, Volume: 2022

    Topics: Animals; Blood Pressure; Choline; Hypertension; Methylamines; Microbiota; Nutrition Surveys; Oxides; Rats; Rats, Inbred SHR; Water

2022
Curcumin attenuates cadmium-induced atherosclerosis by regulating trimethylamine-N-oxide synthesis and macrophage polarization through remodeling the gut microbiota.
    Ecotoxicology and environmental safety, 2022, Oct-01, Volume: 244

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Cadmium; Curcumin; Gastrointestinal Microbiome; Macrophages; Methylamines; Mice; Oxides; Water

2022
Trimethylamine-N-oxide (TMAO) promotes balloon injury-induced neointimal hyperplasia via upregulating Beclin1 and impairing autophagic flux.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 155

    Topics: Animals; Anti-Bacterial Agents; Beclin-1; Carotid Artery Injuries; Cell Proliferation; Endothelial Cells; Eosine Yellowish-(YS); Hematoxylin; Hyperplasia; Muscle, Smooth, Vascular; Neointima; Oxides; Rats; Rats, Sprague-Dawley

2022
Monosodium glutamate consumption reduces the renal excretion of trimethylamine N-oxide and the abundance of Akkermansia muciniphila in the gut.
    Biochemical and biophysical research communications, 2022, 11-19, Volume: 630

    Topics: Akkermansia; Animals; Dimethylamines; Drinking Water; Intestines; Lipocalin-2; Male; Methylamines; Mucins; Rats; Rats, Wistar; Renal Elimination; Sodium Glutamate; Verrucomicrobia

2022
Residual Risk of Trimethylamine-N-Oxide and Choline for Stroke Recurrence in Patients With Intensive Secondary Therapy.
    Journal of the American Heart Association, 2022, 10-04, Volume: 11, Issue:19

    Topics: C-Reactive Protein; Choline; Humans; Inflammation; Lipids; Methylamines; Oxides; Platelet Aggregation Inhibitors; Risk Factors; Stroke

2022
Trimethylamine-N-Oxide Promotes Osteoclast Differentiation and Bone Loss via Activating ROS-Dependent NF-κB Signaling Pathway.
    Nutrients, 2022, Sep-23, Volume: 14, Issue:19

    Topics: Acetylcysteine; Actins; Animals; Bone Resorption; Cattle; Cell Differentiation; Methylamines; Mice; Mice, Inbred C57BL; NF-kappa B; NFATC Transcription Factors; Nitriles; Osteoclasts; Osteogenesis; Osteoporosis; Oxides; Proto-Oncogene Proteins c-fos; RANK Ligand; Reactive Oxygen Species; Signal Transduction; Sulfones; TNF Receptor-Associated Factor 6

2022
Related factors based on non-targeted metabolomics methods in minor ischaemic stroke.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Biomarkers; Blood Glucose; Brain Ischemia; C-Reactive Protein; Homocysteine; Humans; Hypertension; Ischemic Stroke; Lactic Acid; Methylamines; Oxides; Pyruvic Acid; Stroke

2022
Trimethylamine, a gut bacteria metabolite and air pollutant, increases blood pressure and markers of kidney damage including proteinuria and KIM-1 in rats.
    Journal of translational medicine, 2022, 10-15, Volume: 20, Issue:1

    Topics: Air Pollutants; Animals; Bacteria; Biomarkers; Blood Pressure; Creatinine; Flavins; Kidney; Kidney Diseases; Male; Methylamines; Mixed Function Oxygenases; Proteinuria; Rats; Water

2022
TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis.
    International journal of molecular sciences, 2022, Oct-11, Volume: 23, Issue:20

    Topics: Animals; Atherosclerosis; Betaine; Cardiovascular Diseases; Carnitine; Choline; Humans; Inflammation; Methylamines; Mice; MicroRNAs

2022
Choline and butyrate beneficially modulate the gut microbiome without affecting atherosclerosis in APOE*3-Leiden.CETP mice.
    Atherosclerosis, 2022, Volume: 362

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Butyrates; Cholesterol Ester Transfer Proteins; Choline; Female; Gastrointestinal Microbiome; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE

2022
Higher serum trimethylamine-N-oxide levels are associated with increased abdominal aortic calcification in hemodialysis patients.
    Renal failure, 2022, Volume: 44, Issue:1

    Topics: Cross-Sectional Studies; Humans; Oxides; Parathyroid Hormone; Renal Dialysis; Vascular Calcification

2022
Quercetin inhibits hepatotoxic effects by reducing trimethylamine-
    Food & function, 2023, Jan-03, Volume: 14, Issue:1

    Topics: Animals; Carnitine; Diet; Methylamines; Mice; Mice, Inbred C57BL; Oxides; Quercetin

2023
Association of Circulating Trimethylamine-N Oxide With Malnutrition and the Risk of Coronary Artery Disease in Patients With Maintenance Hemodialysis.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2023, Volume: 33, Issue:3

    Topics: Cardiovascular Diseases; Coronary Artery Disease; Humans; Malnutrition; Oxides; Renal Dialysis

2023
Dietary Methionine Restriction Alleviates Choline-Induced Tri-Methylamine-N-Oxide (TMAO) Elevation by Manipulating Gut Microbiota in Mice.
    Nutrients, 2023, Jan-01, Volume: 15, Issue:1

    Topics: Animals; Bacteria; Choline; Gastrointestinal Microbiome; Humans; Methionine; Methylamines; Mice; Racemethionine

2023
Iodomethylcholine Inhibits Trimethylamine-N-Oxide Production and Averts Maternal Chronic Kidney Disease-Programmed Offspring Hypertension.
    International journal of molecular sciences, 2023, Jan-09, Volume: 24, Issue:2

    Topics: Animals; Female; Humans; Hypertension; Hypertrophy; Methylamines; Oxides; Pregnancy; Rats; Renal Insufficiency, Chronic

2023
GUT MICROBIOTA COMPOSITION AND ITS METABOLITES CHANGES IN PATIENTS WITH ATHEROSCLEROSIS AND ATRIAL FIBRILLATION.
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2022, Volume: 75, Issue:12

    Topics: Atherosclerosis; Atrial Fibrillation; Bacteria; Gastrointestinal Microbiome; Humans

2022
Serum trimethylamine-
    Renal failure, 2023, Volume: 45, Issue:1

    Topics: Methylamines; Oxides

2023
Letter to the editor about published meta-analysis of TMAO and stroke.
    European journal of clinical nutrition, 2023, Volume: 77, Issue:7

    Topics: Gastrointestinal Microbiome; Humans; Oxides; Stroke

2023
Association between plasma trimethylamine-N-oxide and cognitive impairment in patients with transient ischemic attack.
    Neurological research, 2023, Volume: 45, Issue:7

    Topics: Aged; Cognitive Dysfunction; Humans; Ischemic Attack, Transient; Male; Oxides; Retrospective Studies; Stroke

2023
Trimethylamine-N-oxide sensitizes chondrocytes to mechanical loading through the upregulation of Piezo1.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2023, Volume: 175

    Topics: Animals; Apoptosis; Calcium; Chondrocytes; Mechanotransduction, Cellular; Osteoarthritis; Oxides; Rats; Up-Regulation

2023
Chronic oral trimethylamine-N-oxide administration induces experimental incipient atherosclerosis in non-genetically modified mice.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2022, Volume: 73, Issue:5

    Topics: Animals; Atherosclerosis; C-Reactive Protein; Cholesterol; Inflammation; Male; Mice; Oxides; Rats; Rats, Wistar; Triglycerides; Tumor Necrosis Factor-alpha

2022
TRIMETHYLAMINE OXIDE - FACTOR IN THE DEVELOPMENT OF ATHEROSCLEROSIS AND A POTENTIAL TARGET FOR DIETARY AND PHARMACOLOGICAL INTERVENTIONS.
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2023, Volume: 51, Issue:1

    Topics: Atherosclerosis; Carnitine; Choline; Humans; Methylamines

2023
Contractile effect of trimethylamine and trimethylamine-n-oxide on isolated human umbilical arteries.
    The journal of obstetrics and gynaecology research, 2023, Volume: 49, Issue:7

    Topics: Humans; Methylamines; Oxides; Umbilical Arteries

2023
The Acute Effect of Trimethylamine-N-Oxide on Vascular Function, Oxidative Stress, and Inflammation in Rat Aortic Rings.
    Cardiovascular toxicology, 2023, Volume: 23, Issue:5-6

    Topics: Animals; Inflammation; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Oxides; Rats; Superoxide Dismutase-1; Vasodilator Agents

2023
Increased Thermostability of an Engineered Flavin-Containing Monooxygenase to Remediate Trimethylamine in Fish Protein Hydrolysates.
    Applied and environmental microbiology, 2023, 06-28, Volume: 89, Issue:6

    Topics: Animals; Methylamines; Protein Hydrolysates

2023
Docosahexaenoic Acid Alleviates Trimethylamine-
    Nutrients, 2023, May-04, Volume: 15, Issue:9

    Topics: Docosahexaenoic Acids; Endothelial Progenitor Cells; Glutathione Disulfide; Humans; MicroRNAs; Neovascularization, Pathologic; Oxides; Proto-Oncogene Proteins c-akt

2023
Alterations in trimethylamine-N-oxide in response to Empagliflozin therapy: a secondary analysis of the EMMY trial.
    Cardiovascular diabetology, 2023, 07-20, Volume: 22, Issue:1

    Topics: Aged; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Myocardial Infarction; Oxides; Sodium-Glucose Transporter 2 Inhibitors

2023
Dietary phenolics and their microbial metabolites are poor inhibitors of trimethylamine oxidation to trimethylamine N-oxide by hepatic flavin monooxygenase 3.
    The Journal of nutritional biochemistry, 2023, Volume: 120

    Topics: Animals; Chlorogenic Acid; Choline; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenols; Rats

2023
A normative microbiome is not restored following kidney transplantation.
    Clinical science (London, England : 1979), 2023, 10-31, Volume: 137, Issue:20

    Topics: Dysbiosis; Gastrointestinal Microbiome; Humans; Kidney Transplantation; Microbiota; Renal Insufficiency, Chronic

2023
Mangiferin alleviates trimethylamine-
    Food & function, 2023, Oct-16, Volume: 14, Issue:20

    Topics: Animals; Atherosclerosis; Cholesterol; Choline; Female; Gastrointestinal Microbiome; Methylamines; Mice; Oxides; Xanthones

2023
Identification of Polymethoxyflavones (PMFs) from Orange Peel and Their Inhibitory Effects on the Formation of Trimethylamine (TMA) and Trimethylamine-N-oxide (TMAO) Using cntA/B and cutC/D Enzymes and Molecular Docking.
    Journal of agricultural and food chemistry, 2023, Nov-01, Volume: 71, Issue:43

    Topics: Cardiovascular Diseases; Citrus sinensis; Methylamines; Molecular Docking Simulation; Oxides

2023
Time-dependent specific molecular signatures of inflammation and remodelling are associated with trimethylamine-N-oxide (TMAO)-induced endothelial cell dysfunction.
    Scientific reports, 2023, Nov-20, Volume: 13, Issue:1

    Topics: Endothelial Cells; Humans; Inflammation; Methylamines; Oxides; Vascular Diseases

2023