trimethylamine and choline

trimethylamine has been researched along with choline in 110 studies

Research

Studies (110)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (13.64)	18.7374
1990's	10 (9.09)	18.2507
2000's	10 (9.09)	29.6817
2010's	40 (36.36)	24.3611
2020's	35 (31.82)	2.80

Authors

Authors	Studies
Dudley, F; Marks, R; Wan, A	1
Pauszek, ME	1
Balaban, RS; Berkowitz, BA; Eng, J	1
Gettner, S; Youssef, M; Zeisel, SH	1
daCosta, KA; Hensey, S; Youssef, M; Zeisel, SH	1
Charest, RP; Chenoweth, M; Dunn, A	1
Chase, T; Sandhu, SS	1
Brydon, WG; Eastwood, MA; Lowis, S	1
Hansen, RC; Rothschild, JG	1
Goldstein, L; King, PA	1
Charest, R; Dunn, A	1
Goolamali, SK; Spellacy, E; Watts, RW	1
Blusztajn, JK; Wishnok, JS; Zeisel, SH	1
Alexander, M; Thomas, JM	1
Butler, EJ; Fenwick, GR; Pearson, AW	1
Aiello, F; Chen, H	1
Felipo, V; Grisolía, S; Hermenegildo, C; Llsansola, M; Miñana, MD; Montoliu, C	1
Ellory, JC; Flanagan, GJ; O'Kelly, J; Rae, C; Winearls, CG	1
Bain, MD; Burns, SP; Chalmers, RA; Holmes, HC; Iles, RA; Kordoni, V; Michelakakis, H; Rafter, JE	1
Brewster, M; McConnell, HW; Mitchell, SC; Smith, RL	1
Albuquerque, EX; Alkondon, M; Cortes, WS; Maelicke, A; Pereira, EF	1
Mitchell, SC; Smith, RL; Zhang, AQ	2
Buist, R; Dawood, MR; Hiebert, T; Johnston, JB; Peeling, J; Power, C; Silva, C	1
Pardini, RS; Sapien, RE	1
ACKERMANN, D; LIST, PH	1
DE LA HUERGA, J; POPPER, H; STEIGMANN, F	1
Arêas, JA; Lanfer-Marquez, UM; Podadera, P; Sipahi, AM	1
Busby, MG; da Costa, KA; Fischer, L; Mar, MH; Thompson, D; Zeisel, SH	1
Ding, Y; Mou, S	1
Dänicke, S; Reese, K; Ueberschär, KH; Weigend, S	1
Ferrari, ND; Nield, LS	1
Zhang, J; Zhu, Y	1
Arima, J; Ichiyanagi, T; Mohamed Ahmed, IA; Mori, N; Sakuno, E	1
Gadda, G; Gannavaram, S; Nguyen, T; Pennati, A; Quaye, O	1
Bhatnagar, D; Chaturvedi, S; Devi, MM; Khan, AR; Khushu, S; Rana, P; Tripathi, RP; Tyagi, R	1
Ji, F; Qi, GH; Wang, J; Wu, SG; Xia, ZQ; Xu, L; Yue, HY; Zhang, HJ	1
Baek, HH; Shim, JE	1
Balskus, EP; Craciun, S	1
Thibodeaux, CJ; van der Donk, WA	1
Allayee, H; Bennett, BJ; Crooke, R; de Aguiar Vallim, TQ; Edwards, PA; Graham, M; Gregory, J; Hazen, SL; Lee, R; Lusis, AJ; Meng, Y; Shih, DM; Wang, Z	1
Ji, F; Qi, GH; Wang, J; Wu, SG; Xu, L; Yue, HY; Zhang, HJ	1
Miller, MJ	1
Balskus, EP; Craciun, S; Marks, JA	1
Chambers, ST; Elmslie, JL; Florkowski, CM; George, PM; Krebs, JD; Lever, M; Lunt, H; McEntyre, CJ; Slow, S	1
Hazen, SL; Tang, WH	1
Bennett, BJ; Buffa, JA; DiDonato, JA; Gregory, JC; Hazen, SL; Levison, BS; Li, L; Lusis, AJ; Org, E; Wagner, MA; Wang, Z; Zhu, W	1
Abbara, S; Boccara, F; Capeau, J; Fitch, KV; Gauguier, D; Grinspoon, SK; Kadar, H; Knight, R; Lo, J; Srinivasa, S; Wong, K	1
Allenspach, M; Linseisen, J; Müller, D; Rohrmann, S; von Eckardstein, A	1
Buffa, JA; Culley, MK; DiDonato, AJ; DiDonato, JA; Fu, X; Gu, X; Hazen, JE; Hazen, SL; Huang, Y; Krajcik, D; Levison, BS; Lusis, AJ; Org, E; Roberts, AB; Wang, Z; Zamanian-Daryoush, M; Zhu, W	1
Awwad, HM; Geisel, J; Graeber, S; Herrmann, W; Obeid, R; Rabagny, Y	1
Hennig, B; Hoffman, JB; Morris, AJ; Perkins, JT; Petriello, MC; Sunkara, M; Wahlang, B	1
Balskus, EP; Bodea, S; Drennan, CL; Funk, MA	1
Liu, C; Liu, J; Yin, Y; Zhao, M; Zheng, L; Zhou, J	1
Broderick, JB; Moody, JD	1
Chmurzynska, A; Malinowska, AM; Szwengiel, A	1
Blesso, CN; Caudill, MA; DiMarco, DM; Fernandez, ML; Lemos, BS; Malysheva, OV; Missimer, A; Murillo, AG	1
Burdick-Will, A; Chang, X; Chen, Y; Duke, FF; Eades, J; Fakharzadeh, S; Fennessey, P; Guo, Y; Hakonarson, H; Hwang, LD; Jiang, H; Keating, BJ; Li, J; Mansfield, C; Preti, G; Reed, DR; Yu, CW; Zhang, J	1
Shen, TD	1
Chen, X; Guo, Y; Li, X; Pi, J; Yang, N; Yuan, G; Zhang, H; Zheng, J	1
Allayee, H; Buffa, JA; Cajka, T; DiDonato, JA; Fiehn, O; Gu, X; Han, Y; Hartiala, JA; Hazen, SL; Hurd, AG; Kerby, RL; Li, L; Li, XS; Lüscher, TF; Nemet, I; Obeid, S; Rey, FE; Roberts, AB; Romano, KA; Shahen, CJ; Skye, SM; Tang, WHW; Wagner, MA; Wang, Z; Wu, Y	1
Chen, Y; Jameson, E; Quareshy, M	1
Balskus, EP; Bodea, S	1
Airs, R; Chen, Y; Jameson, E; Jones, H; Kaster, AK; Millard, A; Murrell, JC; Purdy, KJ; Stephenson, J	1
Balskus, EP; Levin, BJ	1
Bry, L; Crothers, J	1
DiDonato, JA; Fischbach, MA; Guo, CJ; Haag, B; Hazen, SL; Jia, X; Kirsop, J; Lang, JM; Lusis, AJ; Rey, FE; Romano, KA; Skye, SM; Tang, WHW; Wang, Z; Zhu, W	1
Balskus, EP; Chittim, CL; Martínez Del Campo, A	1
Bresciani, L; Brighenti, F; Calani, L; Dall'Asta, M; Del Rio, D; Favari, C	1
Abidin, S; Bhandari, U; Gautam, A; Paudel, YN	1
Allayee, H; Brown, JM; Cantor, RM; Graham, M; Hazen, SL; Jia, X; Lee, R; Lusis, AJ; Meng, Y; Miikeda, A; Mueller, C; Schugar, RC; Shih, DM; Wang, Z; Zhu, W; Zieger, M	1
Chen, L; Wu, J; Yang, H; Zhao, X	1
Aguesse, A; Billon-Crossouard, S; Croyal, M; Ene, L; Guebre-Egziabher, F; Juillard, L; Krempf, M; Lemoine, S; Pelletier, CC; Soulage, CO	1
Chen, H; Li, Q; Liu, R; Wu, T; Zhang, M; Zhang, Z	1
García-Cañas, V; Simó, C	1
Allison, J; Arboleya, S; Arias, JL; Arias, N; Gueimonde, M; Higarza, SG; Kaliszewska, A	1
Hwang, KT; Lee, K; Lim, T; Park, SY; Ryu, J	1
Gabr, M; Świderek, K	1
Chu, W; Heng, X; Liu, W	1
Bernieh, D; Cassambai, S; Heaney, LM; Israr, MZ; Jones, DJL; Ng, LL; Salzano, A; Suzuki, T; Yazaki, Y	1
Chen, GY; Chepyala, D; Chiu, HH; Kuo, CH; Kuo, HC; Lu, WH	1
Du, Y; Hong, B; Jiang, J; Jiang, Z; Li, X; Su, C; Wang, L; Yang, M; Yang, Y; Zhang, J; Zhang, X; Zhang, Y	1
Essenmacher, LA; Iglesias-Carres, L; Neilson, AP; Racine, KC	1
Day-Walsh, P; Kellingray, L; Kroon, PA; Narbad, A; Nemeckova, B; Saha, S; Savva, GM; Shehata, E; Speranza, J	1
Emoto, T; Gotoh, Y; Hayashi, T; Hirata, KI; Kami, K; Matsumoto, K; Saito, Y; Tabata, T; Takahashi, T; Tanaka, H; Watanabe, H; Yamada, T; Yamashita, T; Yoshida, N	1
Bergström, M; Fagerström, C; Hefni, ME; Lennqvist, T; Witthöft, CM	1
Cao, Z; Guo, X; Liu, L; Wang, X; Xie, C; Yang, P; Zhang, Q	1
Chen, H; Li, Q; Liu, R; Wu, T; Zhang, M	1
Buawangpong, N; Chattipakorn, N; Chattipakorn, SC; Pinyopornpanish, K; Siri-Angkul, N	1
Allen, FM; Anderson, JT; Armstrong, AR; Banerjee, R; Brown, AL; Brown, JM; Buffa, JA; Burrows, A; Cook, K; Ferguson, D; Finney, C; Fung, KK; Garcia-Garcia, JC; Gliniak, CM; Goudarzi, M; Gromovsky, AD; Hazen, SL; Helsley, RN; Horak, A; Keshavarzian, A; Lusis, AJ; Mak, TD; Massey, W; McMillan, A; Mehrabian, M; Neumann, C; Orabi, D; Osborn, LJ; Sangwan, N; Schugar, RC; Swanson, G; Wang, Z; Willard, B	1
Dey, M; Dhakal, S; Moazzami, Z; Perry, C	1
Herring, JA; Iglesias-Carres, L; Krueger, ES; Neilson, AP; Tessem, JS	1
Alolga, RN; Cai, YY; Gao, X; Huang, FQ; Lao, X; Li, J; Liu, B; Lu, Y; Qi, LW; Shang, J; Wang, Y; Yin, K; Zhou, X	1
Iglesias-Carres, L; Neilson, AP; Racine, KC	1
Anand, N; Chandana, KA; Chidambaram, SB; Kalyan, M; Kanna, PV; Mahalakshmi, AM; Pandi-Perumal, SR; Praveenraj, SS; Sakharkar, MK; Shasthara, P; Sonali, S; Tousif, HA; Vichitra, C; Yang, J	1
Hong, Y; Ji, N; Luo, X; Ma, W; Nie, Z; Shan, J; Xue, J; Zhang, T; Zhang, Y; Zhou, S; Zhu, W	1
Chang, X; Dai, Y; Duan, Z; Guo, J; Qi, X; Tan, R; Wang, Z; Wu, C; Xu, S; Zhang, J; Zhang, Q; Zhou, Z	1
Cao, Y; Chang, X; Dai, Y; Guo, J; Liang, W; Lu, D; Lv, S; Qi, X; Wang, Z; Wu, C; Zhang, J; Zhang, L; Zhou, Z	1
Feng, YQ; He, GD; Liu, XC; Lu, AS	1
Cheng, A; Jiang, X; Jin, A; Li, H; Li, K; Lin, J; Meng, X; Wang, Y; Xu, J; Xue, J; Zhao, M; Zheng, L	1
Blanco, R; Daimiel, L; Dávalos, A; Díez-Ricote, L; Micó, V; Ordovás, JM; Ruiz-Valderrey, P; Tomé-Carneiro, J	1
Boon, MR; Fan, X; Li, Z; Liu, C; Rensen, PCN; Schönke, M; Shao, H; Song, Z; Wang, Y	1
Le, G; Li, B; Lu, M; Wang, X; Xie, Y; Xu, Y; Yang, Y	1
Abe, T; Bhuiya, J; Isomura, M; Kobayashi, H; Nabika, T; Nagai, A; Notsu, Y; Okazaki, R; Sheikh, AM; Shibly, AZ; Yamaguchi, K; Yamasaki, M; Yano, S	1
Guo, X; He, S; He, Y; Li, L; Liang, W; Lin, X; Wang, J; Xiao, Y; Xiong, Q; Ying, C; Zhao, J; Zuo, X	1
Lazar, M; Olma, A; Streb, W	1
Arnindita, JN; Dyah Lamara, A; Oktaviono, YH; Pasahari, D; Saputra, ME; Saputra, PBT; Suasti, NMA	1
Chadwick-Corbin, SA; Iglesias-Carres, L; Neilson, AP; Sweet, MG	1
Chen, ZY; He, Z; Kwek, E; Liu, J; Ma, KY; Zhu, H	1

Reviews

10 review(s) available for trimethylamine and choline

Article	Year
Trimethylaminuria in a girl with Prader-Willi syndrome and del(15)(q11q13). American journal of medical genetics, 1993, Feb-01, Volume: 45, Issue:3 Topics: Animals; Child; Choline; Chromosome Deletion; Chromosomes, Human, Pair 15; Diet; Female; Fishes; Humans; Metabolism, Inborn Errors; Methylamines; Odorants; Oxidoreductases, N-Demethylating; Prader-Willi Syndrome; Syndrome	1993
The contributory role of gut microbiota in cardiovascular disease. The Journal of clinical investigation, 2014, Volume: 124, Issue:10 Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Choline; Diet; Female; Food; Humans; Intestines; Male; Methylamines; Microbiota; Oxygenases; Phosphatidylcholines	2014
Diet and Gut Microbiota in Health and Disease. Nestle Nutrition Institute workshop series, 2017, Volume: 88 Topics: Animals; Bacteria; Choline; Diet; Dietary Carbohydrates; Dysbiosis; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Health Status; Humans; Inflammatory Bowel Diseases; Methylamines; Renal Insufficiency, Chronic	2017
Methodological considerations for the identification of choline and carnitine-degrading bacteria in the gut. Methods (San Diego, Calif.), 2018, 10-01, Volume: 149 Topics: Amino Acid Sequence; Cardiovascular Diseases; Carnitine; Choline; Computational Biology; Diet; Gastrointestinal Microbiome; Humans; Klebsiella pneumoniae; Methylamines; Proteus mirabilis	2018
Discovering radical-dependent enzymes in the human gut microbiota. Current opinion in chemical biology, 2018, Volume: 47 Topics: Choline; Enzymes; Gastrointestinal Microbiome; Humans; Lyases; Metagenome; Methylamines; Propanediol Dehydratase; Proteome	2018
Dietary bioactive ingredients to modulate the gut microbiota-derived metabolite TMAO. New opportunities for functional food development. Food & function, 2020, Aug-01, Volume: 11, Issue:8 Topics: Betaine; Biological Availability; Carnitine; Choline; Diet; Food Ingredients; Functional Food; Gastrointestinal Absorption; Gastrointestinal Microbiome; Gastrointestinal Tract; Heart Disease Risk Factors; Humans; Liver; Methylamines; Oxygenases	2020
The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases. Nutrients, 2020, Aug-05, Volume: 12, Issue:8 Topics: Animals; Biological Availability; Cardiovascular Diseases; Choline; Diet; Dysbiosis; Gastrointestinal Microbiome; Genotype; Humans; Inflammatory Bowel Diseases; Liver; Methylamines; Non-alcoholic Fatty Liver Disease; Renal Insufficiency, Chronic	2020
The role of trimethylamine-N-Oxide in the development of Alzheimer's disease. Journal of cellular physiology, 2022, Volume: 237, Issue:3 Topics: Alzheimer Disease; Animals; Choline; Methylamines; Oxides	2022
The Role of a Gut Microbial-Derived Metabolite, Trimethylamine N-Oxide (TMAO), in Neurological Disorders. Molecular neurobiology, 2022, Volume: 59, Issue:11 Topics: Betaine; Carnitine; Choline; Flavins; Gastrointestinal Microbiome; Humans; Inflammasomes; Lyases; Methylamines; Mixed Function Oxygenases; Nervous System Diseases; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein	2022
The roles of trimethylamine-N-oxide in atherosclerosis and its potential therapeutic aspect: A literature review. Biomolecules & biomedicine, 2023, Nov-03, Volume: 23, Issue:6 Topics: Atherosclerosis; Choline; Endothelial Cells; Humans; Lyases; Oxides; Plaque, Atherosclerotic	2023

Trials

6 trial(s) available for trimethylamine and choline

Article	Year
Dietary precursors of trimethylamine in man: a pilot study. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1999, Volume: 37, Issue:5 Topics: Adult; Choline; Diet; Humans; Male; Methylamines; Oxidants; Pilot Projects; Reference Values	1999
Effect of dietary choline supplementation under different flavin-containing monooxygenase 3 genotypes on trimethylamine metabolism in laying hens. Poultry science, 2012, Volume: 91, Issue:9 Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cecum; Chickens; Choline; Diet; Dietary Supplements; Egg Yolk; Female; Gastrointestinal Contents; Gene Expression Regulation; Genotype; Methylamines; Oviposition; Oxygenases; RNA, Messenger	2012
Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period. Annals of clinical biochemistry, 2015, Volume: 52, Issue:Pt 3 Topics: Aged; Betaine; Choline; Diabetes Mellitus, Type 2; Female; Glycerylphosphorylcholine; Humans; Male; Methylamines; Middle Aged; Overweight; Sarcosine; Taurine; Time Factors	2015
Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential. Circulation research, 2018, 10-26, Volume: 123, Issue:10 Topics: Adult; Animals; Bacterial Proteins; Choline; Clostridium; Fecal Microbiota Transplantation; Female; Gastrointestinal Microbiome; Humans; Lyases; Male; Methylamines; Mice; Mice, Inbred C57BL; Middle Aged; Platelet Activation; Thrombosis	2018
Effects of Lean Pork on Microbiota and Microbial-Metabolite Trimethylamine-N-Oxide: A Randomized Controlled Non-Inferiority Feeding Trial Based on the Dietary Guidelines for Americans. Molecular nutrition & food research, 2022, Volume: 66, Issue:9 Topics: Animals; Choline; Gastrointestinal Microbiome; Humans; Methylamines; Microbiota; Nutrition Policy; Oxides; Pork Meat; Poultry; Red Meat; Swine	2022
The Effect of Inulin-Type Fructans on Plasma Trimethylamine N-Oxide Levels in Peritoneal Dialysis Patients: A Randomized Crossover Trial. Molecular nutrition & food research, 2023, Volume: 67, Issue:9 Topics: Choline; Cross-Over Studies; Fructans; Humans; Inulin; Methylamines; Peritoneal Dialysis	2023

Other Studies

94 other study(ies) available for trimethylamine and choline

Article	Year
Trimethylamine metabolism in liver disease. Lancet (London, England), 1978, May-20, Volume: 1, Issue:8073 Topics: Choline; Chronic Disease; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Methylamines	1978
Fishing for a diagnosis. Indiana medicine : the journal of the Indiana State Medical Association, 1991, Volume: 84, Issue:2 Topics: Adolescent; Choline; Humans; Male; Metabolism, Inborn Errors; Methylamines; Odorants	1991
Renal distribution and metabolism of [2H9]choline. A 2H NMR and MRI study. NMR in biomedicine, 1990, Volume: 3, Issue:4 Topics: Animals; Choline; Deuterium; Furosemide; Infusions, Intravenous; Kidney; Kidney Cortex; Kidney Medulla; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Methylamines; Rabbits; Tissue Distribution	1990
Formation of aliphatic amine precursors of N-nitrosodimethylamine after oral administration of choline and choline analogues in the rat. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1989, Volume: 27, Issue:1 Topics: Administration, Oral; Animals; Choline; Dimethylamines; Dimethylnitrosamine; Intestinal Mucosa; Intestines; Male; Methylamines; Rats; Rats, Inbred Strains	1989
Conversion of dietary choline to trimethylamine and dimethylamine in rats: dose-response relationship. The Journal of nutrition, 1989, Volume: 119, Issue:5 Topics: Animals; Choline; Diet; Dimethylamines; Dose-Response Relationship, Drug; Male; Methylamines; Rats; Rats, Inbred Strains	1989
Metabolism of trimethylamines in kelp bass (Paralabrax clathratus) and marine and freshwater pink salmon (Oncorhynchus gorbuscha). Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 1988, Volume: 158, Issue:5 Topics: Animals; Bass; Betaine; Choline; Dimethylamines; Liver; Methylamines; Muscles; Perciformes; Radioactive Tracers; Salmon; Water-Electrolyte Balance	1988
Aerobic degradation of choline by Proteus mirabilis: enzymatic requirements and pathway. Canadian journal of microbiology, 1986, Volume: 32, Issue:9 Topics: Acetaldehyde; Aerobiosis; Cell-Free System; Choline; Kinetics; Methylamines; Proteus mirabilis	1986
The influence of creatinine, lecithin and choline feeding on aliphatic amine production and excretion in the rat. The British journal of nutrition, 1985, Volume: 54, Issue:1 Topics: Animals; Choline; Creatinine; Diet; Dimethylamines; Male; Methylamines; Phosphatidylcholines; Rats	1985
Fish odor syndrome: trimethylaminuria with milk as chief dietary factor. Pediatric dermatology, 1985, Volume: 3, Issue:1 Topics: Animals; Cattle; Child; Choline; Humans; Infant; Liver; Male; Methylamines; Milk; Syndrome	1985
Renal ammoniagenesis and acid excretion in the dogfish, Squalus acanthias. The American journal of physiology, 1983, Volume: 245, Issue:4 Topics: Amino Acids; Ammonia; Animals; Choline; Dogfish; Female; Fishes; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutaminase; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Kinetics; Methionine; Methylamines; Species Specificity; Urine	1983
Chromatographic separation of choline, trimethylamine, trimethylamine oxide, and betaine from tissues of marine fish. Analytical biochemistry, 1984, Volume: 136, Issue:2 Topics: Animals; Betaine; Carnitine; Choline; Chromatography, Ion Exchange; Fishes; Liver; Methylamines; Muscles; Tissue Extracts	1984
Trimethylaminuria. Journal of inherited metabolic disease, 1980, Volume: 2, Issue:4 Topics: Animals; Child; Choline; Creatinine; Diet; Female; Fishes; Humans; Meat; Metabolism, Inborn Errors; Methylamines; Odorants	1980
Formation of methylamines from ingested choline and lecithin. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:2 Topics: Administration, Oral; Animals; Choline; Chromatography, Gas; Dimethylamines; Drug Contamination; Humans; Methylamines; Phosphatidylcholines; Rats; Rats, Inbred Strains	1983
Microbial formation of secondary and tertiary amines in municipal sewage. Applied and environmental microbiology, 1981, Volume: 42, Issue:3 Topics: Anaerobiosis; Bacteria; Choline; Creatinine; Dimethylamines; Methylamines; Phosphatidylcholines; Sewage	1981
Rapeseed meal and egg taint: the role of sinapine. Journal of the science of food and agriculture, 1980, Volume: 31, Issue:9 Topics: Animals; Brassica; Chickens; Choline; Eggs; Female; Male; Methylamines; Microsomes, Liver; Odorants; Oviposition; Oxidation-Reduction; Oxidoreductases, N-Demethylating	1980
Carnitine and choline derivatives containing a trimethylamine group prevent ammonia toxicity in mice and glutamate toxicity in primary cultures of neurons. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:1 Topics: Ammonia; Animals; Carnitine; Cells, Cultured; Choline; Cycloleucine; Glutamic Acid; Male; Methylamines; Mice; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	1996
Human erythrocyte choline uptake in uraemia: the role of intracellular substrate and an investigation into the effects of haemodialysis. Clinical science (London, England : 1979), 1996, Volume: 91, Issue:3 Topics: Choline; Dimethylamines; Erythrocytes; Female; Humans; Ion Transport; Magnetic Resonance Spectroscopy; Male; Methylamines; Renal Dialysis; Uremia	1996
Choline and L-carnitine as precursors of trimethylamine. Biochemical Society transactions, 1997, Volume: 25, Issue:1 Topics: Animals; Carnitine; Child, Preschool; Choline; Female; Fishes; Humans; Magnetic Resonance Spectroscopy; Meat; Metabolism, Inborn Errors; Methylamines; Reference Values	1997
Trimethylaminuria associated with seizures and behavioural disturbance: a case report. Seizure, 1997, Volume: 6, Issue:4 Topics: Adolescent; Child; Child Behavior Disorders; Choline; Diagnosis, Differential; Epilepsy, Complex Partial; Humans; Male; Metabolism, Inborn Errors; Methylamines; Neurocognitive Disorders; Neuropsychological Tests; Odorants	1997
Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons. The European journal of neuroscience, 1997, Volume: 9, Issue:12 Topics: Acetylcholine; Animals; Bungarotoxins; Choline; Dimethylphenylpiperazinium Iodide; Excitatory Amino Acid Agonists; Hippocampus; Mecamylamine; Methylamines; N-Methylaspartate; Neurons; Nicotinic Agonists; Nicotinic Antagonists; Nootropic Agents; Olfactory Bulb; Patch-Clamp Techniques; PC12 Cells; Rats; Rats, Sprague-Dawley; Thalamus	1997
Dimethylamine formation in the rat from various related amine precursors. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1998, Volume: 36, Issue:11 Topics: Administration, Oral; Animals; Choline; Diet; Dimethylamines; Ethylamines; Male; Methylamines; Oxidants; Propanols; Rats; Rats, Wistar	1998
Neurovirulence depends on virus input titer in brain in feline immunodeficiency virus infection: evidence for activation of innate immunity and neuronal injury. Journal of neurovirology, 2002, Volume: 8, Issue:5 Topics: Animals; Animals, Newborn; Aspartic Acid; Brain; Cats; CD4-Positive T-Lymphocytes; Cells, Cultured; Choline; Culture Media, Conditioned; Disease Models, Animal; Feline Acquired Immunodeficiency Syndrome; Gliosis; Immunity, Innate; Immunodeficiency Virus, Feline; Macrophages; Magnetic Resonance Spectroscopy; Methylamines; Neurons; Virulence	2002
Trimethylaminuria (fish odor syndrome) related to the choline concentration of infant formula. Pediatric emergency care, 2003, Volume: 19, Issue:2 Topics: Choline; Halitosis; Humans; Infant; Infant Food; Male; Metabolism, Inborn Errors; Methylamines; Odorants; Oxygenases	2003
[Incidence of herzynine, ergothioneine, homarine, trigonelline, glycocoll betaine, choline, trimethylamine, adenine and almost all amino acids of proteins in Limulus polyphemus L]. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1958, Volume: 313 Topics: Adenine; Alkaloids; Amines; Amino Acids; Animals; Betaine; Choline; Crustacea; Ergothioneine; Glycine; Histidine; Horseshoe Crabs; Incidence; Methylamines; Niacin; Nicotinic Acids; Picolines; Picolinic Acids	1958
Urinary excretion of choline and trimethylamines after intravenous administration of choline in liver diseases. The Journal of laboratory and clinical medicine, 1951, Volume: 38, Issue:6 Topics: Administration, Intravenous; Choline; Humans; Liver Diseases; Liver Function Tests; Methylamines	1951
Choline: there's something fishy about this vitamin. Harvard health letter, 2004, Volume: 30, Issue:1 Topics: Animals; Choline; Female; Fishes; Humans; Male; Methylamines; Nutrition Policy; Odorants	2004
Diagnosis of suspected trimethylaminuria by NMR spectroscopy. Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 351, Issue:1-2 Topics: Adult; Amines; Animals; Choline; Diet; Dogfish; Humans; Magnetic Resonance Spectroscopy; Male; Metabolism, Inborn Errors; Methylamines; Odorants; Oxidation-Reduction; Reference Standards; Solutions	2005
Choline- and betaine-defined diets for use in clinical research and for the management of trimethylaminuria. Journal of the American Dietetic Association, 2004, Volume: 104, Issue:12 Topics: Betaine; Choline; Dietary Supplements; Dietetics; Dose-Response Relationship, Drug; Food Analysis; Humans; Metabolism, Inborn Errors; Methylamines; Methylation; Nutrition Policy; Nutritional Requirements; Practice Guidelines as Topic	2004
[Determination of choline chloride and trimethylamine in feedstuff by ion chromatography]. Se pu = Chinese journal of chromatography, 2004, Volume: 22, Issue:2 Topics: Animal Feed; Animals; Choline; Chromatography, Ion Exchange; Methylamines	2004
Investigations on the effects of rape oil quality, choline and methionine concentration in diets for laying hens on the trimethylamine content of the eggs, on trimethylamine metabolism and on laying performance. Archives of animal nutrition, 2006, Volume: 60, Issue:1 Topics: Analysis of Variance; Animal Feed; Animals; Chickens; Choline; Dose-Response Relationship, Drug; Eggs; Fatty Acids, Monounsaturated; Female; Methionine; Methylamines; Oviposition; Plant Oils; Random Allocation; Rapeseed Oil	2006
Smelling like dead fish: a case of trimethylaminuria in an adolescent. Clinical pediatrics, 2006, Volume: 45, Issue:9 Topics: Adolescent; Anti-Infective Agents; Biomarkers; Carnitine; Choline; Creatinine; Humans; Male; Metabolism, Inborn Errors; Methylamines; Nootropic Agents	2006
Determination of betaine, choline and trimethylamine in feed additive by ion-exchange liquid chromatography/non-suppressed conductivity detection. Journal of chromatography. A, 2007, Nov-02, Volume: 1170, Issue:1-2 Topics: Animal Feed; Betaine; Cation Exchange Resins; Cations; Choline; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Electric Conductivity; Methylamines; Reference Standards; Reproducibility of Results	2007
Isolation and characterization of 3-N-trimethylamino-1-propanol-degrading Rhodococcus sp. strain A2. FEMS microbiology letters, 2009, Volume: 296, Issue:2 Topics: Aerobiosis; beta-Alanine; Choline; Cluster Analysis; DNA, Bacterial; DNA, Ribosomal; Metabolic Networks and Pathways; Methylamines; Molecular Sequence Data; Phylogeny; Rhodococcus; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Soil Microbiology	2009
Rescuing of the hydride transfer reaction in the Glu312Asp variant of choline oxidase by a substrate analogue. Archives of biochemistry and biophysics, 2010, Volume: 499, Issue:1-2 Topics: Alcohol Oxidoreductases; Amino Acid Substitution; Arthrobacter; Catalytic Domain; Choline; Genetic Variation; Hydrogen-Ion Concentration; Kinetics; Methylamines; Substrate Specificity	2010
Study of acute biochemical effects of thallium toxicity in mouse urine by NMR spectroscopy. Journal of applied toxicology : JAT, 2011, Volume: 31, Issue:7 Topics: 3-Hydroxybutyric Acid; Animals; Choline; Creatinine; Heavy Metal Poisoning; Hippurates; Magnetic Resonance Spectroscopy; Male; Metabolomics; Metals, Heavy; Methylamines; Mice; Mice, Inbred A; Poisoning; Principal Component Analysis; Taurine; Thallium	2011
Determination of trimethylamine in spinach, cabbage, and lettuce at alkaline pH by headspace solid-phase microextraction. Journal of food science, 2012, Volume: 77, Issue:10 Topics: Adsorption; Betaine; Brassica; Carnitine; Choline; Dimethylpolysiloxanes; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Lactuca; Methylamines; Polyvinyls; Reproducibility of Results; Solid Phase Microextraction; Spinacia oleracea; Taste; Temperature	2012
Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme. Proceedings of the National Academy of Sciences of the United States of America, 2012, Dec-26, Volume: 109, Issue:52 Topics: Anaerobiosis; Choline; Computational Biology; Desulfovibrio desulfuricans; Electron Spin Resonance Spectroscopy; Free Radicals; Genes, Bacterial; Genetic Association Studies; Glycine; Humans; Lyases; Methylamines; Multigene Family; Mutation	2012
Converging on a mechanism for choline degradation. Proceedings of the National Academy of Sciences of the United States of America, 2012, Dec-26, Volume: 109, Issue:52 Topics: Choline; Desulfovibrio desulfuricans; Free Radicals; Glycine; Humans; Lyases; Methylamines	2012
Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. Cell metabolism, 2013, Jan-08, Volume: 17, Issue:1 Topics: Androgens; Animals; Atherosclerosis; Base Sequence; Bile Acids and Salts; Choline; Diet; Down-Regulation; Female; Gene Silencing; HEK293 Cells; Humans; Male; Methylamines; Mice; Mice, Knockout; Oxygenases; Polymorphism, Single Nucleotide; Receptors, Cytoplasmic and Nuclear; Sex Factors	2013
Trimethylamine deposition in the egg yolk from laying hens with different FMO3 genotypes. Poultry science, 2013, Volume: 92, Issue:3 Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Choline; Diet; Dose-Response Relationship, Drug; Egg Yolk; Eggs; Female; Gene Expression Regulation, Enzymologic; Genotype; Methylamines; Oviposition; Oxygenases	2013
Risk factors for cardiovascular disease: a cautionary tale of diet-microbiome interactions. Journal of the American College of Nutrition, 2013, Volume: 32, Issue:2 Topics: Cardiovascular Diseases; Carnitine; Choline; Diet; Gastrointestinal Tract; Humans; Methylamines; Microbiota; Risk Factors	2013
Characterization of choline trimethylamine-lyase expands the chemistry of glycyl radical enzymes. ACS chemical biology, 2014, Jul-18, Volume: 9, Issue:7 Topics: Bacterial Proteins; Choline; Cloning, Molecular; Desulfovibrio; Electron Spin Resonance Spectroscopy; Enzyme Activation; Escherichia coli; Glycine; Humans; Lyases; Methylamines; Models, Molecular; Substrate Specificity	2014
Transmission of atherosclerosis susceptibility with gut microbial transplantation. The Journal of biological chemistry, 2015, Feb-27, Volume: 290, Issue:9 Topics: Animals; Aorta; Atherosclerosis; Cecum; Choline; Diet; Disease Susceptibility; Female; Gastrointestinal Tract; Host-Pathogen Interactions; Humans; Male; Methylamines; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred Strains; Mice, Knockout; Mice, Transgenic; Microbiota; Species Specificity	2015
Plaque burden in HIV-infected patients is associated with serum intestinal microbiota-generated trimethylamine. AIDS (London, England), 2015, Feb-20, Volume: 29, Issue:4 Topics: Choline; Coronary Artery Disease; Dysbiosis; Female; HIV Infections; Humans; Intestinal Diseases; Male; Methylamines; Middle Aged; Plaque, Atherosclerotic; Prognosis; Risk Assessment; Risk Factors	2015
Plasma Concentrations of Trimethylamine-N-oxide Are Directly Associated with Dairy Food Consumption and Low-Grade Inflammation in a German Adult Population. The Journal of nutrition, 2016, Volume: 146, Issue:2 Topics: Adult; Animals; Betaine; C-Reactive Protein; Choline; Dairy Products; Diet; Diet Surveys; Feeding Behavior; Female; Germany; Humans; Inflammation; Interleukin-6; Male; Methylamines; Middle Aged; Milk; Receptors, Tumor Necrosis Factor, Type I; Tumor Necrosis Factor-alpha	2016
Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis. Cell, 2015, Dec-17, Volume: 163, Issue:7 Topics: Animals; Apolipoproteins E; Atherosclerosis; Cholesterol; Choline; Diet; Feces; Foam Cells; Gastrointestinal Tract; Hexanols; Humans; Lyases; Methylamines; Mice; Mice, Inbred C57BL; Microbiota	2015
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism. The American journal of clinical nutrition, 2016, Volume: 103, Issue:3 Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Gastrointestinal Microbiome; Humans; Lipoproteins, HDL; Male; Methylamines; Methylation; Middle Aged; Phosphatidylcholines; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors	2016
Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors. The Journal of nutritional biochemistry, 2016, Volume: 33 Topics: Administration, Oral; Animals; Atherosclerosis; Biomarkers; Choline; Deuterium; Dietary Fats; Environmental Pollutants; Enzyme Induction; Food-Drug Interactions; Liver; Male; Methylamines; Mice, Inbred C57BL; Oxygenases; Phosphatidylcholines; Polychlorinated Biphenyls; Random Allocation; Up-Regulation	2016
Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase. Cell chemical biology, 2016, Oct-20, Volume: 23, Issue:10 Topics: Bacterial Proteins; Catalytic Domain; Choline; Crystallography, X-Ray; Desulfovibrio; Hydrogen Bonding; Lyases; Methylamines; Models, Molecular; Protein Conformation; Substrate Specificity	2016
Simultaneous targeted analysis of trimethylamine-N-oxide, choline, betaine, and carnitine by high performance liquid chromatography tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016, Nov-01, Volume: 1035 Topics: Animals; Betaine; Carnitine; Choline; Chromatography, High Pressure Liquid; Male; Methylamines; Mice; Mice, Inbred C57BL; Tandem Mass Spectrometry	2016
Cutting Choline with Radical Scissors. Cell chemical biology, 2016, 10-20, Volume: 23, Issue:10 Topics: Choline; Gastrointestinal Microbiome; Humans; Lyases; Methylamines	2016
Dietary, anthropometric, and biochemical factors influencing plasma choline, carnitine, trimethylamine, and trimethylamine-N-oxide concentrations. International journal of food sciences and nutrition, 2017, Volume: 68, Issue:4 Topics: Aged; Body Size; Carnitine; Choline; Diet; Female; Humans; Methylamines; Middle Aged	2017
Intake of up to 3 Eggs/Day Increases HDL Cholesterol and Plasma Choline While Plasma Trimethylamine-N-oxide is Unchanged in a Healthy Population. Lipids, 2017, Volume: 52, Issue:3 Topics: Adult; Anthropometry; Blood Pressure; Cholesterol, HDL; Cholesterol, LDL; Choline; Eggs; Female; Healthy Volunteers; Humans; Male; Methylamines; Waist Circumference; Young Adult	2017
Genetic analysis of impaired trimethylamine metabolism using whole exome sequencing. BMC medical genetics, 2017, Feb-15, Volume: 18, Issue:1 Topics: Adolescent; Adult; Aged; Choline; DNA; Female; Genetic Testing; Genotype; Humans; INDEL Mutation; Male; Metabolism, Inborn Errors; Methylamines; Middle Aged; Oxygenases; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Smell	2017
Fishy Odor and TMA Content Levels in Duck Egg Yolks. Journal of food science, 2018, Volume: 83, Issue:1 Topics: Animals; China; Choline; Diet; Ducks; Egg Yolk; Female; Gene Expression; Methylamines; Odorants; Oxygenases; Phenotype; Polymorphism, Single Nucleotide	2018
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk. JCI insight, 2018, 03-22, Volume: 3, Issue:6 Topics: Aged; Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Cholesterol; Choline; Disease Models, Animal; Feces; Female; Gastrointestinal Microbiome; Genome-Wide Association Study; Humans; Lysine; Male; Metabolomics; Methylamines; Mice; Mice, Inbred C57BL; Middle Aged; Nutrients; Risk Factors; Thrombosis	2018
Purification and Characterization of the Choline Trimethylamine-Lyase (CutC)-Activating Protein CutD. Methods in enzymology, 2018, Volume: 606 Topics: Adaptor Proteins, Signal Transducing; Bacterial Proteins; Choline; Cloning, Molecular; Desulfovibrio; Electron Spin Resonance Spectroscopy; Enzyme Assays; Lyases; Methylamines; Protein Processing, Post-Translational; Recombinant Proteins; S-Adenosylmethionine	2018
Deltaproteobacteria (Pelobacter) and Methanococcoides are responsible for choline-dependent methanogenesis in a coastal saltmarsh sediment. The ISME journal, 2019, Volume: 13, Issue:2 Topics: Choline; Deltaproteobacteria; Geologic Sediments; High-Throughput Nucleotide Sequencing; Metagenome; Metagenomics; Methane; Methanosarcinaceae; Methylamines; RNA, Ribosomal, 16S; Wetlands	2019
Gutting TMA to Save the Heart. Cell host & microbe, 2018, 10-10, Volume: 24, Issue:4 Topics: Animals; Cardiovascular Diseases; Choline; Diet; Gastrointestinal Microbiome; Gastrointestinal Tract; Host Microbial Interactions; Humans; Methylamines; Mice; Mice, Knockout	2018
Gut bacterial phospholipase Ds support disease-associated metabolism by generating choline. Nature microbiology, 2019, Volume: 4, Issue:1 Topics: Choline; Escherichia coli; Gastrointestinal Microbiome; Humans; Methylamines; Phosphatidylcholines; Phospholipase D	2019
An in vitro exploratory study of dietary strategies based on polyphenol-rich beverages, fruit juices and oils to control trimethylamine production in the colon. Food & function, 2018, Dec-13, Volume: 9, Issue:12 Topics: Adult; Bacteria; Biotransformation; Carnitine; Choline; Colon; Diet; Feces; Female; Fruit and Vegetable Juices; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Oils; Polyphenols; Young Adult	2018
Guggulsterone, a farnesoid X receptor antagonist lowers plasma trimethylamine- Human & experimental toxicology, 2019, Volume: 38, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; Cardiotonic Agents; Choline; Clostridium; Diet; Escherichia; Hypolipidemic Agents; Kidney; Lipid Peroxidation; Liver; Methylamines; Myocardium; Pregnenediones; Rats, Wistar; Receptors, Cytoplasmic and Nuclear	2019
Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report. Arteriosclerosis, thrombosis, and vascular biology, 2019, Volume: 39, Issue:6 Topics: Animals; Atherosclerosis; Choline; Disease Models, Animal; Lipid Metabolism; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxygenases; Polymerase Chain Reaction; Random Allocation; Reference Values; Thrombosis	2019
Effect of vacuum impregnated fish gelatin and grape seed extract on metabolite profiles of tilapia (Oreochromis niloticus) fillets during storage. Food chemistry, 2019, Sep-30, Volume: 293 Topics: Animals; Choline; Cichlids; Fish Products; Food Storage; Gelatin; Grape Seed Extract; Histidine; Magnetic Resonance Spectroscopy; Methylamines; Multivariate Analysis; Vacuum	2019
Elevation of Trimethylamine-N-Oxide in Chronic Kidney Disease: Contribution of Decreased Glomerular Filtration Rate. Toxins, 2019, 11-01, Volume: 11, Issue:11 Topics: Adult; Betaine; Choline; Creatinine; Female; Gastrointestinal Microbiome; Glomerular Filtration Rate; Humans; Male; Metabolic Clearance Rate; Methylamines; Middle Aged; Prospective Studies; Renal Dialysis; Renal Insufficiency, Chronic	2019
Potential Correlation between Dietary Fiber-Suppressed Microbial Conversion of Choline to Trimethylamine and Formation of Methylglyoxal. Journal of agricultural and food chemistry, 2019, Dec-04, Volume: 67, Issue:48 Topics: Animal Feed; Animals; Bacteria; Choline; Dietary Fiber; Gastrointestinal Microbiome; Gastrointestinal Tract; Glycine; Methylamines; Mice; Mice, Inbred C57BL; Pyruvaldehyde; Red Meat	2019
Protective Effects of Black Raspberry ( Nutrients, 2020, Aug-14, Volume: 12, Issue:8 Topics: Animals; Anthocyanins; Cecum; Choline; Cyclooxygenase 2; Diet, High-Fat; Dietary Supplements; Eating; Female; Hepatitis; Hypercholesterolemia; Interleukin-1beta; Liver; Methylamines; NF-kappa B; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Rubus	2020
Discovery of a Histidine-Based Scaffold as an Inhibitor of Gut Microbial Choline Trimethylamine-Lyase. ChemMedChem, 2020, 12-03, Volume: 15, Issue:23 Topics: Choline; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Gastrointestinal Microbiome; Histidine; Humans; Lyases; Methylamines; Molecular Docking Simulation; Molecular Structure	2020
Identification of choline-degrading bacteria from healthy human feces and used for screening of trimethylamine (TMA)-lyase inhibitors. Microbial pathogenesis, 2021, Volume: 152 Topics: Bacteria; Choline; Feces; Humans; Lyases; Methylamines; RNA, Ribosomal, 16S	2021
Association of gut-related metabolites with outcome in acute heart failure. American heart journal, 2021, Volume: 234 Topics: Acetylcarnitine; Acute Disease; Aged; Aged, 80 and over; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Heart Failure; Hospital Mortality; Humans; Male; Methylamines; Natriuretic Peptide, Brain; Risk Factors; Statistics, Nonparametric	2021
Using matrix-induced ion suppression combined with LC-MS/MS for quantification of trimethylamine-N-oxide, choline, carnitine and acetylcarnitine in dried blood spot samples. Analytica chimica acta, 2021, Mar-08, Volume: 1149 Topics: Acetylcarnitine; Carnitine; Choline; Chromatography, Liquid; Dried Blood Spot Testing; Humans; Methylamines; Oxides; Reproducibility of Results; Tandem Mass Spectrometry	2021
Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome. NPJ biofilms and microbiomes, 2021, 04-16, Volume: 7, Issue:1 Topics: Animals; Atherosclerosis; Berberine; Choline; Diet; Disease Models, Animal; Disease Susceptibility; Dysbiosis; Gastrointestinal Microbiome; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE	2021
Development of a High-Throughput Method to Study the Inhibitory Effect of Phytochemicals on Trimethylamine Formation. Nutrients, 2021, Apr-26, Volume: 13, Issue:5 Topics: Chlorogenic Acid; Choline; Feces; Fermentation; Gallic Acid; High-Throughput Screening Assays; Humans; Methylamines; Phenylenediamines; Phytochemicals	2021
The use of an in-vitro batch fermentation (human colon) model for investigating mechanisms of TMA production from choline, L-carnitine and related precursors by the human gut microbiota. European journal of nutrition, 2021, Volume: 60, Issue:7 Topics: Animals; Carnitine; Choline; Colon; Fermentation; Gastrointestinal Microbiome; Humans; Methylamines	2021
Metagenomic analysis of gut microbiota reveals its role in trimethylamine metabolism in heart failure. International journal of cardiology, 2021, 09-01, Volume: 338 Topics: Choline; Gastrointestinal Microbiome; Heart Failure; Humans; Metagenome; Methylamines; RNA, Ribosomal, 16S	2021
Simultaneous quantification of trimethylamine N-oxide, trimethylamine, choline, betaine, creatinine, and propionyl-, acetyl-, and L-carnitine in clinical and food samples using HILIC-LC-MS. Analytical and bioanalytical chemistry, 2021, Volume: 413, Issue:21 Topics: Betaine; Carnitine; Choline; Chromatography, Liquid; Creatinine; Female; Food Analysis; Humans; Limit of Detection; Male; Methylamines; Middle Aged; Tandem Mass Spectrometry	2021
Unraveling the metabolic pathway of choline-TMA-TMAO: Effects of gypenosides and implications for the therapy of TMAO related diseases. Pharmacological research, 2021, Volume: 173 Topics: Animals; Brain; Choline; Feces; Female; Gastrointestinal Microbiome; Gynostemma; Lipid Metabolism; Methylamines; Mice, Inbred BALB C; Microsomes, Liver; Oxygenases; Plant Extracts; RNA, Ribosomal, 16S	2021
Induction of the glycolysis product methylglyoxal on trimethylamine lyase synthesis in the intestinal microbiota from mice fed with choline and dietary fiber. Food & function, 2021, Oct-19, Volume: 12, Issue:20 Topics: Animals; Choline; Diet; Dietary Fiber; Feces; Female; Gastrointestinal Microbiome; Glycine; Glycolysis; Lyases; Metabolomics; Metagenomics; Methylamines; Mice; Mice, Inbred C57BL; Pyruvaldehyde; RNA, Ribosomal, 16S	2021
Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms. eLife, 2022, 01-24, Volume: 11 Topics: Animals; Choline; Circadian Rhythm; Diet, High-Fat; Enzyme Inhibitors; Gastrointestinal Microbiome; Leptin; Lyases; Male; Methylamines; Mice; Mice, Inbred C57BL; Obesity	2022
Potential of Phenolic Compounds and Their Gut Microbiota-Derived Metabolites to Reduce TMA Formation: Application of an Journal of agricultural and food chemistry, 2022, Mar-16, Volume: 70, Issue:10 Topics: Choline; Fermentation; Gastrointestinal Microbiome; High-Throughput Screening Assays; Humans; Methylamines	2022
Integrated metagenomics identifies a crucial role for trimethylamine-producing Lachnoclostridium in promoting atherosclerosis. NPJ biofilms and microbiomes, 2022, 03-10, Volume: 8, Issue:1 Topics: Animals; Atherosclerosis; Choline; Gastrointestinal Microbiome; Humans; Metagenomics; Methylamines; Mice	2022
Phenolic-rich beverages reduce bacterial TMA formation in an Food & function, 2022, Aug-01, Volume: 13, Issue:15 Topics: Atherosclerosis; Bacteria; Beverages; Chlorogenic Acid; Choline; Coffee; Fermentation; Humans; Methylamines	2022
Gut-Flora-Dependent Metabolite Trimethylamine-N-Oxide Promotes Atherosclerosis-Associated Inflammation Responses by Indirect ROS Stimulation and Signaling Involving AMPK and SIRT1. Nutrients, 2022, Aug-15, Volume: 14, Issue:16 Topics: AMP-Activated Protein Kinases; Animals; Atherosclerosis; Choline; Gastrointestinal Microbiome; Inflammation; Methylamines; Mice; Oxides; Reactive Oxygen Species; Sirtuin 1	2022
Associations of Diet with Urinary Trimethylamine-N-Oxide (TMAO) and Its Precursors among Free-Living 10-Year-Old Children: Data from SMBCS. Nutrients, 2022, Aug-19, Volume: 14, Issue:16 Topics: Animals; Choline; Diet; Humans; Meat; Methylamines; Oxides	2022
Multiple mediation effects on association between prenatal triclosan exposure and birth outcomes. Environmental research, 2022, Volume: 215, Issue:Pt 1 Topics: Acetylcarnitine; Bayes Theorem; Betaine; Choline; Cohort Studies; Estradiol; Female; Humans; Leptin; Maternal Exposure; Methylamines; Oxides; Pregnancy; Testosterone; Thyroid Hormones; Thyroxine; Triclosan	2022
Association of Choline Intake with Blood Pressure and Effects of Its Microbiota-Dependent Metabolite Trimethylamine-N-Oxide on Hypertension. Cardiovascular therapeutics, 2022, Volume: 2022 Topics: Animals; Blood Pressure; Choline; Hypertension; Methylamines; Microbiota; Nutrition Surveys; Oxides; Rats; Rats, Inbred SHR; Water	2022
Residual Risk of Trimethylamine-N-Oxide and Choline for Stroke Recurrence in Patients With Intensive Secondary Therapy. Journal of the American Heart Association, 2022, 10-04, Volume: 11, Issue:19 Topics: C-Reactive Protein; Choline; Humans; Inflammation; Lipids; Methylamines; Oxides; Platelet Aggregation Inhibitors; Risk Factors; Stroke	2022
TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis. International journal of molecular sciences, 2022, Oct-11, Volume: 23, Issue:20 Topics: Animals; Atherosclerosis; Betaine; Cardiovascular Diseases; Carnitine; Choline; Humans; Inflammation; Methylamines; Mice; MicroRNAs	2022
Choline and butyrate beneficially modulate the gut microbiome without affecting atherosclerosis in APOE3-Leiden.CETP mice. Atherosclerosis, 2022, Volume: 362* Topics: Animals; Apolipoproteins E; Atherosclerosis; Butyrates; Cholesterol Ester Transfer Proteins; Choline; Female; Gastrointestinal Microbiome; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE	2022
Dietary Methionine Restriction Alleviates Choline-Induced Tri-Methylamine-N-Oxide (TMAO) Elevation by Manipulating Gut Microbiota in Mice. Nutrients, 2023, Jan-01, Volume: 15, Issue:1 Topics: Animals; Bacteria; Choline; Gastrointestinal Microbiome; Humans; Methionine; Methylamines; Mice; Racemethionine	2023
Neither Trimethylamine-N-Oxide nor Trimethyllysine Is Associated with Atherosclerosis: A Cross-Sectional Study in Older Japanese Adults. Nutrients, 2023, Feb-02, Volume: 15, Issue:3 Topics: Animals; Atherosclerosis; Carnitine; Carotid Intima-Media Thickness; Choline; Cross-Sectional Studies; East Asian People; Female; Humans; Methylamines; Oxides	2023
TRIMETHYLAMINE OXIDE - FACTOR IN THE DEVELOPMENT OF ATHEROSCLEROSIS AND A POTENTIAL TARGET FOR DIETARY AND PHARMACOLOGICAL INTERVENTIONS. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2023, Volume: 51, Issue:1 Topics: Atherosclerosis; Carnitine; Choline; Humans; Methylamines	2023
Dietary phenolics and their microbial metabolites are poor inhibitors of trimethylamine oxidation to trimethylamine N-oxide by hepatic flavin monooxygenase 3. The Journal of nutritional biochemistry, 2023, Volume: 120 Topics: Animals; Chlorogenic Acid; Choline; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenols; Rats	2023
Mangiferin alleviates trimethylamine- Food & function, 2023, Oct-16, Volume: 14, Issue:20 Topics: Animals; Atherosclerosis; Cholesterol; Choline; Female; Gastrointestinal Microbiome; Methylamines; Mice; Oxides; Xanthones	2023