Page last updated: 2024-08-16

trimethoprim and warfarin

trimethoprim has been researched along with warfarin in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (40.00)	18.7374
1990's	1 (2.50)	18.2507
2000's	8 (20.00)	29.6817
2010's	13 (32.50)	24.3611
2020's	2 (5.00)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Avdeef, A; Tam, KY	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bajusz, D; Balogh, GT; Dargó, G; Müller, J; Simon, K	1
Kashihara, M; Mizuguchi, M; Yokoyama, T	1
Feetam, CL; Hassall, C; Leach, RH; Meynell, MJ	1
Motley, CH; O'Reilly, RA	1
Greenlaw, CW	1
Serlin, MJ	1
Fries, AS; Ladefoged, O	1
Errick, JK; Keys, PW	1
Gray, JM; Lawson, DH; Nimmo-Smith, RH; Tilstone, WJ	1
De Swiet, J	1
Raasch, RH	1
Chandrasekar, PH; DeLorenzo, W; Levine, DP; Unowsky, J	1
Perkash, A	1
Brooks, BJ; Mocklin, KE	1
O'Reilly, RA	1
Fauver, HE; Kaufman, JM	1
Blaauboer, BJ; Noordhoek, J; van 't Klooster, GA; van Miert, AS; Woutersen-van Nijnanten, FM	1
Cornish, VW; Gallagher, SS; Jing, C; Kaufman, LJ; Konate, M; Peterka, DS; Wombacher, R; Yuste, R	1
Aonbangkhen, C; Chenoweth, DM; Lampson, MA; Wu, DZ; Zhang, H	1

Reviews

1 review(s) available for trimethoprim and warfarin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

39 other study(ies) available for trimethoprim and warfarin

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design. Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4 Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Pharmaceutical Preparations; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Titrimetry	2020
Repositioning of the Anthelmintic Drugs Bithionol and Triclabendazole as Transthyretin Amyloidogenesis Inhibitors. Journal of medicinal chemistry, 2021, 10-14, Volume: 64, Issue:19 Topics: Amyloid Neuropathies, Familial; Anthelmintics; Bithionol; Crystallography, X-Ray; Drug Repositioning; Humans; Prealbumin; Thermodynamics; Triclabendazole	2021
Letter: Potentiation of warfarin by co-trimoxazole. Lancet (London, England), 1975, Dec-06, Volume: 2, Issue:7945 Topics: Adult; Aged; Drug Combinations; Drug Synergism; Humans; Middle Aged; Prothrombin; Sulfamethoxazole; Trimethoprim; Warfarin	1975
Racemic warfarin and trimethoprim-sulfamethoxazole interaction in humans. Annals of internal medicine, 1979, Volume: 91, Issue:1 Topics: Adult; Drug Combinations; Drug Interactions; Humans; Male; Prospective Studies; Prothrombin Time; Sulfamethoxazole; Trimethoprim; Warfarin	1979
Drug interaction between co-trimoxazole and warfarin. American journal of hospital pharmacy, 1979, Volume: 36, Issue:9 Topics: Aged; Drug Combinations; Drug Interactions; Female; Humans; Prothrombin Time; Sulfamethoxazole; Trimethoprim; Warfarin	1979
Antimicrobial drug interactions with oral anticoagulants. The Journal of antimicrobial chemotherapy, 1979, Volume: 5, Issue:6 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Anticoagulants; Coumarins; Drug Interactions; Drug Synergism; Humans; Sulfamethoxazole; Trimethoprim	1979
The influence of Bacillus piliformis (Tyzzer) infections on the reliability of pharmacokinetic experiments in mice. Laboratory animals, 1979, Volume: 13, Issue:3 Topics: Animals; Bacillus; Bacterial Infections; Liver; Male; Mice; Rodent Diseases; Trimethoprim; Warfarin	1979
Co-trimoxazole and warfarin: case report of an interaction. American journal of hospital pharmacy, 1978, Volume: 35, Issue:11 Topics: Aged; Drug Combinations; Drug Synergism; Female; Humans; Sulfamethoxazole; Trimethoprim; Warfarin	1978
Interaction between warfarin and sulphamethoxazole. Postgraduate medical journal, 1977, Volume: 53, Issue:621 Topics: Adult; Binding Sites; Drug Combinations; Drug Interactions; Female; Humans; In Vitro Techniques; Protein Binding; Prothrombin Time; Serum Albumin; Sulfamethoxazole; Trimethoprim; Warfarin	1977
Letter: Potentiations of warfarin by co-trimoxazole. British medical journal, 1975, Jun-21, Volume: 2, Issue:5972 Topics: Drug Synergism; Humans; Phenytoin; Prothrombin Time; Sulfamethoxazole; Trimethoprim; Warfarin	1975
Letter: Potentiation of warfarin by co-trimoxazole. British medical journal, 1975, Aug-23, Volume: 3, Issue:5981 Topics: Drug Combinations; Drug Synergism; Humans; Hypoprothrombinemias; Phenindione; Sulfamethoxazole; Trimethoprim; Warfarin	1975
Interactions of oral antibiotics and common chronic medications. Geriatrics, 1987, Volume: 42, Issue:1 Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Allopurinol; Ampicillin; Antacids; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Digoxin; Drug Combinations; Drug Interactions; Erythromycin; Humans; Sulfamethoxazole; Sulfonamides; Sulfonylurea Compounds; Tetracycline; Theophylline; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Warfarin	1987
In vitro and in vivo activity of coumermycin and other antibacterial agents against methicillin-resistant strains of Staphylococcus aureus. Chemotherapy, 1986, Volume: 32, Issue:6 Topics: Aminocoumarins; Animals; Anti-Bacterial Agents; Coumarins; Drug Combinations; Female; Fusidic Acid; Methicillin; Mice; Microbial Sensitivity Tests; Neutropenia; Penicillin Resistance; Staphylococcal Infections; Staphylococcus aureus; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin	1986
Experience with the management of deep vein thrombosis in patients with spinal cord injury. Part II: a critical evaluation of the anticoagulant therapy. Paraplegia, 1980, Volume: 18, Issue:1 Topics: Administration, Oral; Adult; Anticoagulants; Drug Combinations; Drug Interactions; Hematuria; Heparin; Humans; Injections, Subcutaneous; Male; Middle Aged; Pulmonary Embolism; Spinal Cord Injuries; Sulfamethoxazole; Thrombophlebitis; Time Factors; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Warfarin	1980
Retropharyngeal hematoma as a complication of warfarin therapy. The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1981, Volume: 133, Issue:10 Topics: Aged; Atrial Fibrillation; Drug Interactions; Female; Hematoma; Humans; Pharyngeal Diseases; Pharynx; Radiography; Sulfamethoxazole; Trimethoprim; Urinary Tract Infections; Warfarin; Whole Blood Coagulation Time	1981
Stereoselective interaction of trimethoprim-sulfamethoxazole with the separated enantiomorphs of racemic warfarin in man. The New England journal of medicine, 1980, Jan-03, Volume: 302, Issue:1 Topics: Adult; Drug Interactions; Humans; Male; Prothrombin Time; Stereoisomerism; Structure-Activity Relationship; Sulfamethoxazole; Trimethoprim; Warfarin	1980
Potentiation of warfarin by trimethoprim-sulfamethoxazole. Urology, 1980, Volume: 16, Issue:6 Topics: Aged; Drug Synergism; Epistaxis; Female; Hematuria; Humans; Male; Middle Aged; Sulfamethoxazole; Trimethoprim; Warfarin	1980
Applicability of cultured hepatocytes derived from goat, sheep and cattle in comparative drug metabolism studies. Xenobiotica; the fate of foreign compounds in biological systems, 1994, Volume: 24, Issue:5 Topics: Animals; Biotransformation; Cattle; Cell Differentiation; Cells, Cultured; Coumarins; Cytochrome P-450 Enzyme System; Ethylmorphine; Female; Glucuronates; Goats; Liver; Male; Naphthols; Oxidation-Reduction; Phenolsulfonphthalein; Rats; Rats, Wistar; Sex Factors; Sheep; Species Specificity; Sulfates; Trimethoprim; Xenobiotics	1994
A trimethoprim-based chemical tag for live cell two-photon imaging. Chembiochem : a European journal of chemical biology, 2010, Apr-12, Volume: 11, Issue:6 Topics: Cell Line; Coumarins; Escherichia coli; Fluorescent Dyes; Humans; Microscopy, Fluorescence; Pyrimidines; Rhodamines; Tetrahydrofolate Dehydrogenase; Trimethoprim	2010
Reversible Control of Protein Localization in Living Cells Using a Photocaged-Photocleavable Chemical Dimerizer. Journal of the American Chemical Society, 2018, 09-26, Volume: 140, Issue:38 Topics: Bacterial Proteins; Coumarins; Drug Design; Escherichia coli; HeLa Cells; Humans; Indicators and Reagents; Kinetochores; Listeria monocytogenes; Mitochondria; Peroxisomes; Protein Multimerization; Rhodococcus; Trimethoprim; Ultraviolet Rays	2018