Page last updated: 2024-08-16

trimethoprim and triamterene

trimethoprim has been researched along with triamterene in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19904 (17.39)18.7374
1990's1 (4.35)18.2507
2000's11 (47.83)29.6817
2010's6 (26.09)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Heilmann, E1
Gauldie, J; Hiebert, M; Hillcoat, BL; Marshall, L1
Scott, JM; Weir, DG1
Anguita, T1
Cabot, JL; Evans, AM; Hsyu, PH; Nation, RL; Shanahan, KM1
Amitai, Y; Leventhal, A1
Dong, Q; Huang, YP; Liu, ZS; Peng, C; Wang, XH; Zhang, J1
Dong, Q; Huang, YP; Liu, HL; Liu, ZS; Wang, XH; Xie, LF1

Reviews

3 review(s) available for trimethoprim and triamterene

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Drug-induced megaloblastic anemia].
    Medizinische Klinik, 1979, Aug-24, Volume: 74, Issue:34

    Topics: Alcoholism; Anemia, Macrocytic; Anemia, Megaloblastic; Anti-Bacterial Agents; Anticonvulsants; Antimetabolites, Antineoplastic; Contraceptives, Oral; Drug-Related Side Effects and Adverse Reactions; Folic Acid Antagonists; Humans; Malabsorption Syndromes; Pyrimethamine; Triamterene; Trimethoprim; Vitamin B 12

1979
Drug-induced megaloblastic change.
    Clinics in haematology, 1980, Volume: 9, Issue:3

    Topics: Cyclophosphamide; Cytarabine; DNA; Erythrocytes, Abnormal; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Hydroxyurea; Megaloblasts; Methotrexate; Phenytoin; Pyrimethamine; Ribonucleotides; Thymidine Monophosphate; Thymidylate Synthase; Triamterene; Trimethoprim

1980

Other Studies

20 other study(ies) available for trimethoprim and triamterene

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship

2003
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Stabilization of dihydrofolate reductase by inhibitors in vivo and in vitro.
    Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186

    Topics: Animals; Biodegradation, Environmental; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chromatography, Gel; Cycloheximide; Drug Stability; Electrophoresis; Enzyme Activation; Folic Acid Antagonists; Humans; Leucovorin; Leukemia L1210; Liver Neoplasms; Methotrexate; Mice; Rats; Tetrahydrofolate Dehydrogenase; Triamterene; Trimethoprim

1971
[Bone marrow megaloblastosis associated with the use of pyrimethamine, triamterene and trimethoprim-sulfamethoxazole].
    Revista medica de Chile, 1982, Volume: 110, Issue:6

    Topics: Adult; Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Drug Combinations; Female; Folic Acid Antagonists; Humans; Male; Megaloblasts; Middle Aged; Pyrimethamine; Sulfamethoxazole; Triamterene; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1982
Effect of cationic drugs on the renal secretion of ranitidine in the rat isolated perfused kidney.
    Clinical and experimental pharmacology & physiology, 1998, Volume: 25, Issue:1

    Topics: Amantadine; Animals; Cations; Ephedrine; In Vitro Techniques; Kidney; Male; Perfusion; Protein Binding; Ranitidine; Rats; Rats, Sprague-Dawley; Triamterene; Trimethoprim

1998
Folic acid antagonists during pregnancy and risk of birth defects.
    The New England journal of medicine, 2001, Mar-22, Volume: 344, Issue:12

    Topics: Abnormalities, Drug-Induced; Cleft Lip; Female; Folic Acid Antagonists; Heart Defects, Congenital; Humans; Pregnancy; Sulfasalazine; Triamterene; Trimethoprim; Urinary Tract

2001
Comparison of multi-recognition molecularly imprinted polymers for recognition of melamine, cyromazine, triamterene, and trimethoprim.
    Analytical and bioanalytical chemistry, 2015, Volume: 407, Issue:23

    Topics: Chromatography, High Pressure Liquid; Complex Mixtures; Ionic Liquids; Molecular Imprinting; Polymers; Triamterene; Triazines; Trimethoprim

2015
Synthesis of monodisperse molecularly imprinted microspheres with multi-recognition ability via precipitation polymerization for the selective extraction of cyromazine, melamine, triamterene and trimethoprim.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015, Dec-15, Volume: 1007

    Topics: Humans; Limit of Detection; Microscopy, Electron, Scanning; Microspheres; Polymerization; Triamterene; Triazines; Trimethoprim

2015