trimethoprim has been researched along with primaquine in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (30.77) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 8 (30.77) | 29.6817 |
| 2010's | 6 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Genther, CS; Smith, CS | 1 |
| Queener, SF | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Davidson, DE; Hickman, RL; Johnsen, DO; Kinnamon, KE; Tanticharoenyos, P | 1 |
| Costantino, M | 1 |
| Zhang, ZH | 1 |
| Laakso, T; Sjöholm, I; Stjärnkvist, P | 1 |
| Botelho, A | 1 |
| Botha, D | 1 |
| Bruce-Chwatt, LJ | 1 |
| Dubin, NH; Ghodgaonkar, RB; King, TM; Parmley, TH | 1 |
| Lizasoain, M; Lumbreras, C; Pastor, C | 1 |
| Korraa, H; Saadeh, C | 1 |
| Lewis, BD; López-Rebollar, LM; Penzhorn, BL; Swan, GE | 1 |
| Nishikawa, M; Ogino, T; Ohta, T; Ono-Ogata, T; Yamagata, H | 1 |
| Binh, TQ; de Vries, PJ; Giao, PT; Hung, le Q; Kager, PA; Nam, NV | 1 |
| Ashton, M; Friberg Hietala, S; Hai, TN; Röshammar, D; Van Huong, N | 1 |
| Bellamy, R | 1 |
5 review(s) available for trimethoprim and primaquine
| Article | Year |
|---|---|
New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.
Topics: Animals; Drug Design; Humans; Immunosuppression Therapy; Molecular Structure; Opportunistic Infections; Pneumonia, Pneumocystis; Structure-Activity Relationship | 1995 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Current alternatives in the treatment of Pneumocystis carinii pneumonia in patients with AIDS].
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Atovaquone; Clindamycin; Dapsone; Eflornithine; Humans; Naphthoquinones; Pneumonia, Pneumocystis; Primaquine; Trimethoprim; Trimetrexate | 1994 |
Options in the management of pneumonia caused by Pneumocystis carinii in patients with acquired immune deficiency syndrome and intolerance to trimethoprim/sulfamethoxazole.
Topics: Adrenal Cortex Hormones; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Agents; Atovaquone; Clindamycin; Dapsone; Drug Combinations; Drug Hypersensitivity; Drug Resistance, Microbial; Humans; Leucovorin; Naphthoquinones; Pentamidine; Pneumonia, Pneumocystis; Primaquine; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate | 1996 |
Pneumocystis pneumonia in people with HIV.
Topics: Anti-Infective Agents; Antiprotozoal Agents; Atovaquone; Clindamycin; Dapsone; Drug Therapy, Combination; HIV Infections; Humans; Pentamidine; Pneumonia, Pneumocystis; Primaquine; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 2006 |
2 trial(s) available for trimethoprim and primaquine
| Article | Year |
|---|---|
CV8, a new combination of dihydroartemisinin, piperaquine, trimethoprim and primaquine, compared with atovaquone-proguanil against falciparum malaria in Vietnam.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Atovaquone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Parasitemia; Plasmodium falciparum; Primaquine; Proguanil; Quinolines; Sesquiterpenes; Treatment Outcome; Trimethoprim; Vietnam | 2004 |
Pharmacokinetics of piperaquine after repeated oral administration of the antimalarial combination CV8 in 12 healthy male subjects.
Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Chromatography, High Pressure Liquid; Drug Combinations; Fasting; Half-Life; Humans; Male; Middle Aged; Pilot Projects; Primaquine; Quinolines; Sesquiterpenes; Trimethoprim | 2006 |
19 other study(ies) available for trimethoprim and primaquine
| Article | Year |
|---|---|
Antifolate studies. Activities of 40 potential antimalarial compounds against sensitive and chlorguanide triazine resistant strains of folate-requiring bacteria and Escherichia coli.
Topics: Animals; Antimalarials; Bacteria; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Folic Acid Antagonists; Malaria; Mice; Plasmodium berghei; Triazines | 1977 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Evaluating new antimalarial drugs against trophozoite induced Plasmodium cynomolgi malaria in rhesus monkeys.
Topics: Amodiaquine; Animals; Antimalarials; Dapsone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Tolerance; Haplorhini; Macaca mulatta; Malaria; Phenanthrenes; Primaquine; Prodigiosin; Pyrimethamine; Quinine; Sulfadiazine; Sulfadimethoxine; Sulfalene; Trimethoprim | 1976 |
[Some aspects of the treatment of HIV infection].
Topics: Acquired Immunodeficiency Syndrome; Clindamycin; Dapsone; HIV Infections; Humans; Primaquine; Trimethoprim; Trimetrexate; Zidovudine | 1991 |
Elimination of the gametocytes of Theileria annulata of cattle by primaquin phosphate.
Topics: Animals; Antiprotozoal Agents; Apicomplexa; Cattle; Erythrocytes; Primaquine; Quinolinium Compounds; Sulfamethoxypyridazine; Suramin; Theileriasis; Trimethoprim; Urea | 1987 |
Biodegradable microspheres. VI: Lysosomal release of covalently bound antiparasitic drugs from starch microparticles.
Topics: Animals; Biodegradation, Environmental; Chemical Phenomena; Chemistry; Drug Compounding; Humans; Imidazoles; Kinetics; Lysosomes; Mice; Microspheres; Peptides; Primaquine; Solubility; Starch; Trimethoprim | 1987 |
Considerations on the use of sulphones and sulphonamides with a pyrimidine derivative.
Topics: Adult; Amodiaquine; Child; Dapsone; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Mozambique; Plasmodium falciparum; Plasmodium malariae; Primaquine; Pyrimethamine; Sulfonamides; Trimethoprim | 1974 |
Some pharmacological aspects of antimalarial drugs.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Sulfonamides; Trimethoprim | 1974 |
The role of drugs in a malaria program.
Topics: Amodiaquine; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Humans; Malaria; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Recurrence; Sulfonamides; Sulfones; Trimethoprim | 1972 |
Comparative effects of intrauterine instillation of analogues of quinacrine and tetracycline on uterine morphology in the rat.
Topics: Animals; Chloroquine; Demeclocycline; Doxycycline; Female; Primaquine; Quinacrine; Rats; Rats, Inbred Strains; Sodium Chloride; Tetracycline; Tetracyclines; Trimethoprim; Uterus | 1984 |
Screening of five drugs for efficacy against Babesia felis in experimentally infected cats.
Topics: Animals; Anti-Infective Agents; Antiprotozoal Agents; Babesiosis; Cat Diseases; Cats; Drug Combinations; Enrofloxacin; Fluoroquinolones; Hematocrit; Naphthoquinones; Parasitemia; Primaquine; Quinolones; Rifampin; Sulfadiazine; Trimethoprim | 2000 |
Mutagenic activity and mutational specificity of antiprotozoal drugs with and without nitrite treatment.
Topics: Aminoquinolines; Animals; Antiprotozoal Agents; Drug Therapy, Combination; Escherichia coli; Mutagenicity Tests; Mutagens; Mutation; Nitrites; Primaquine; Pyrimethamine; Pyrimidines; Rats; Salmonella typhimurium; Trimethoprim | 2002 |