Page last updated: 2024-08-16

trimethoprim and prednisolone

trimethoprim has been researched along with prednisolone in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199013 (30.23)18.7374
1990's6 (13.95)18.2507
2000's12 (27.91)29.6817
2010's12 (27.91)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Crippen, GM1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Akamatsu, M1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kochhar, RC; Seth, HN; Singh, D1
Aderele, WI; Johnson, A; Seriki, O; Smith, JA1
Gallasch, G; Holz, FG; Tetz, M; Völcker, HE1
Anandi, V; Balraj, A; Raman, R1
Kondo, H1
Koike, T; Kurasawa, K; Matsumura, R; Ohshima, H; Sugiyama, T; Takabayashi, K; Tomioka, H; Yamazaki, S; Yoshida, H; Yoshida, S1
Hellyar, A; Leaker, B; Mansell, M; Neild, GH; Rudge, C; Thompson, FD1
Lindström, FD; Locht, H1
Fukuda, K; Matsuyama, H; Ohyama, M; Shimada, K; Uchizono, A; Yuasa, K1
Gross, WL; Steppat, D1
Himmunknan, P; Piamphongsant, T; Sirimachan, S1
Eskola, J; Haapaniemi, J; Puhakka, H; Ruuskanen, O; Tuohimaa, P1
Hirose, S; Noto, N; Sugaya, N; Wakabayashi, Y1
Flavell Matts, SG1
Floersheim, GL1
Koppenaal, A; Muntendam, H1
Naspitz, CK; Oliveira, CA; Rachelefsky, GS; Solé, D1
Chandra, R; Majd, M; Park, JS; Pohl, HG; Rushton, HG1
Kato, M; Matsuo, T1
Klein, I; Steenbergen, E; Vervoort, G; Wetzels, J1
Gach, JE; Kaur, MR; Suortamo, S; Wong, L1
Debroy Kidambi, A; Ramsay, HM; Tiffin, NJ1

Reviews

1 review(s) available for trimethoprim and prednisolone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for trimethoprim and prednisolone

ArticleYear
Peroral prednisolone in the treatment of middle-ear effusion in children: a double-blind study.
    Auris, nasus, larynx, 1985, Volume: 12 Suppl 1

    Topics: Administration, Oral; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Infant; Male; Otitis Media with Effusion; Prednisolone; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1985

Other Studies

41 other study(ies) available for trimethoprim and prednisolone

ArticleYear
Validation of EGSITE2, a mixed integer program for deducing objective site models for experimental binding data.
    Journal of medicinal chemistry, 1997, Sep-26, Volume: 40, Issue:20

    Topics: Algorithms; Animals; Binding Sites; Computer Simulation; Folic Acid Antagonists; Models, Molecular; Peptidyl-Dipeptidase A; Protein Binding; Receptors, Cell Surface; Sex Hormone-Binding Globulin; Steroids; Testosterone; Tetrahydrofolate Dehydrogenase; Transcortin

1997
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Rhinoentomophthoromycosis.
    The Journal of laryngology and otology, 1976, Volume: 90, Issue:9

    Topics: Adult; Entomophthora; Fungi; Humans; Male; Mycoses; Nose Diseases; Potassium Iodide; Prednisolone; Sulfamethoxazole; Trimethoprim

1976
Disseminated histoplasmosis due to histoplasma capsulatum in two Nigerian children.
    The Journal of tropical medicine and hygiene, 1975, Volume: 78, Issue:12

    Topics: Amphotericin B; Child; Child, Preschool; Histoplasma; Histoplasmosis; Humans; Male; Nigeria; Prednisolone; Sulfamethoxazole; Trimethoprim

1975
[Segmental retinal arteritis and retinochorioiditis].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1992, Volume: 89, Issue:1

    Topics: Adult; Arteritis; Chorioretinitis; Drug Therapy, Combination; Fluorescein Angiography; Humans; Male; Prednisolone; Pyrimethamine; Retinal Diseases; Sulfamethoxazole; Toxoplasmosis, Ocular; Trimethoprim; Visual Acuity; Visual Field Tests

1992
Nasofacial conidiobolomycosis.
    Ear, nose, & throat journal, 1991, Volume: 70, Issue:10

    Topics: Adolescent; Dermatomycoses; Face; Humans; Male; Mucormycosis; Potassium Iodide; Prednisolone; Sulfamethoxazole; Trimethoprim

1991
[Progress on diagnosis of Wegener's granulomatosis].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991, Nov-10, Volume: 80, Issue:11

    Topics: Adult; Anti-Bacterial Agents; Antibodies, Antineutrophil Cytoplasmic; Autoantibodies; Cyclophosphamide; Drug Therapy, Combination; Female; Granulomatosis with Polyangiitis; Humans; Male; Myeloblastin; Prednisolone; Serine Endopeptidases; Sulfamethoxazole; Trimethoprim

1991
[Pulmonary opportunistic infections in patients with autoimmune diseases].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1989, Volume: 78, Issue:9

    Topics: Adult; Aged; Autoimmune Diseases; Female; Humans; Isoniazid; Lung Diseases, Fungal; Male; Middle Aged; Mycoses; Opportunistic Infections; Pneumonia, Pneumocystis; Prednisolone; Sulfamethoxazole; Trimethoprim; Tuberculosis, Pulmonary

1989
Nocardia infection in a renal transplant unit.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 2

    Topics: Adult; Anti-Infective Agents; Azathioprine; Cross Infection; Cyclosporins; Drug Combinations; Drug Therapy, Combination; Female; Graft Rejection; Hospital Units; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Nocardia Infections; Prednisolone; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1989
Wegener's granulomatosis: treatment failure on conventional therapy.
    The Journal of rheumatology, 1989, Volume: 16, Issue:4

    Topics: Adult; Cyclophosphamide; Granulomatosis with Polyangiitis; Humans; Infusions, Intravenous; Male; Plasmapheresis; Prednisolone; Sulfamethoxazole; Trimethoprim

1989
Three cases of Wegener's granulomatosis treated with an antimicrobial agent.
    Archives of otolaryngology--head & neck surgery, 1989, Volume: 115, Issue:4

    Topics: Adult; Anti-Infective Agents; Azathioprine; Drug Combinations; Drug Therapy, Combination; Female; Granulomatosis with Polyangiitis; Humans; Male; Middle Aged; Prednisolone; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1989
Stage-adapted treatment of Wegener's granulomatosis. First results of a prospective study.
    Klinische Wochenschrift, 1989, Jul-03, Volume: 67, Issue:13

    Topics: Anti-Infective Agents; Cyclophosphamide; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Follow-Up Studies; Granulomatosis with Polyangiitis; Humans; Prednisolone; Prospective Studies; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1989
Juvenile blistering diseases: the problems of diagnosis and treatment.
    Asian Pacific journal of allergy and immunology, 1986, Volume: 4, Issue:2

    Topics: Autoantibodies; Child; Child, Preschool; Complement C3; Dapsone; Dermatitis Herpetiformis; Diagnosis, Differential; Drug Combinations; Female; Fluorescent Antibody Technique; Humans; Immunoglobulin A; Immunoglobulin G; Infant; Male; Prednisolone; Skin Diseases, Vesiculobullous; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1986
[A case of pulmonary nocardiosis in malignant lymphoma under VEMP therapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1985, Volume: 26, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Therapy, Combination; Humans; Lung Diseases; Lymphoma; Male; Mercaptopurine; Nocardia Infections; Prednisolone; Sulfamethoxazole; Trimethoprim; Vincristine

1985
Ulcerative colitis, diverticulitis and the irritable colon syndrome.
    The British journal of clinical practice, 1972, Volume: 26, Issue:2

    Topics: Colitis, Ulcerative; Colonic Diseases, Functional; Diverticulitis, Colonic; Humans; Parasympatholytics; Pentazocine; Prednisolone; Steroids; Sulfamethoxazole; Sulfasalazine; Tetracycline; Trimethoprim

1972
Antagonistic effects to phalloidin, alpha-amanitin and extracts of Amanita phalloides.
    Agents and actions, 1971, Volume: 2, Issue:3

    Topics: Animals; Basidiomycota; Chloramphenicol; Estradiol; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Mycotoxins; Oligopeptides; Penicillin G; Peptides, Cyclic; Phenylbutazone; Plant Extracts; Prednisolone; Rifampin; Sulfadimethoxine; Sulfamethoxazole; Testosterone; Thioctic Acid; Time Factors; Trimethoprim

1971
[Paraplegia syndrome following the use of co-trimoxazole].
    Nederlands tijdschrift voor geneeskunde, 1984, Apr-07, Volume: 128, Issue:14

    Topics: Aged; Anti-Infective Agents, Urinary; Cystitis; Drug Combinations; Female; Humans; Methylprednisolone Hemisuccinate; Paraplegia; Prednisolone; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1984
Improvement of bronchial hyperresponsiveness in asthmatic children treated for concomitant sinusitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1997, Volume: 79, Issue:1

    Topics: Administration, Intranasal; Adolescent; Anti-Infective Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Prednisolone; Sinusitis; Sodium Chloride; Sulfamethoxazole; Trimethoprim

1997
Adjunctive oral corticosteroids reduce renal scarring: the piglet model of reflux and acute experimental pyelonephritis.
    The Journal of urology, 1999, Volume: 162, Issue:3 Pt 1

    Topics: Acute Disease; Animals; Anti-Infective Agents, Urinary; Cicatrix; Drug Therapy, Combination; Glucocorticoids; Male; Prednisolone; Pyelonephritis; Random Allocation; Severity of Illness Index; Sulfamethoxazole; Swine; Trimethoprim; Urinary Tract Infections; Vesico-Ureteral Reflux

1999
Submacular exudates with serous retinal detachment caused by cat scratch disease.
    Ocular immunology and inflammation, 2002, Volume: 10, Issue:2

    Topics: Adult; Bartonella henselae; Cat-Scratch Disease; Drug Therapy, Combination; Exudates and Transudates; Female; Fluorescein Angiography; Humans; Immunoglobulin G; Macula Lutea; Male; Prednisolone; Retinal Detachment; Sulfamethoxazole; Trimethoprim; Visual Acuity

2002
Progressive renal disease despite immunosuppressive therapy in a patient with Wegener s granulomatosis.
    The Netherlands journal of medicine, 2008, Volume: 66, Issue:3

    Topics: Aged; Cyclophosphamide; Disease Progression; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Prednisolone; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

2008
An unusual adverse effect of long-term corticosteroid use.
    Clinical and experimental dermatology, 2011, Volume: 36, Issue:4

    Topics: Adrenal Cortex Hormones; Aged; Anti-Infective Agents; Ciprofloxacin; Female; Groin; Humans; Malacoplakia; Prednisolone; Skin Diseases; Time Factors; Treatment Outcome; Trimethoprim

2011
Atypical rosacea in a male patient: case study.
    Dermatology online journal, 2016, Feb-17, Volume: 22, Issue:2

    Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Dermatologic Agents; Drug Therapy, Combination; Facial Dermatoses; Humans; Isotretinoin; Male; Nose; Prednisolone; Rosacea; Trimethoprim

2016