Page last updated: 2024-08-16

trimethoprim and phenytoin

trimethoprim has been researched along with phenytoin in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (31.58)	18.7374
1990's	0 (0.00)	18.2507
2000's	10 (26.32)	29.6817
2010's	15 (39.47)	24.3611
2020's	1 (2.63)	2.80

Authors

Authors	Studies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Andrews, PR; Craik, DJ; Martin, JL	1
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Akamatsu, M	1
Sen, S; Sinha, N	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Boëthius, G; Sjöqvist, F	1
Moult, PJ; Sherlock, S	1
Debreczeni, LA; Herjavecz, I; Szeitz, A	1
Baird, BJ; De Villez, RL	1
Gillman, MA; Sandyk, R	1
Robenberg, IH	1
Schulz, KH	1
Lalla, M; Virolainen, M	1
Scott, JM; Weir, DG	1
Wilcox, JB	1
Malkiewicz, IM; Neuman, MG; Shear, NH	1
Aga, DS; Ernstoff, AS; Love, NG; Moline, CJ; Stadler, LB; Su, L	1
Brandão, MAF; Ferreira, AO; Patrício, FB; Polonini, HC; Raposo, NRB; Silva, SL	1

Reviews

2 review(s) available for trimethoprim and phenytoin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug-induced megaloblastic change. Clinics in haematology, 1980, Volume: 9, Issue:3 Topics: Cyclophosphamide; Cytarabine; DNA; Erythrocytes, Abnormal; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Hydroxyurea; Megaloblasts; Methotrexate; Phenytoin; Pyrimethamine; Ribonucleotides; Thymidine Monophosphate; Thymidylate Synthase; Triamterene; Trimethoprim	1980

Other Studies

36 other study(ies) available for trimethoprim and phenytoin

Article	Year
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11 Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Importance of physicochemical properties for the design of new pesticides. Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7 Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic	2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Doses and dosage intervals of drugs--clinical practice and pharmacokinetic principles. Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:3 Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Antidepressive Agents, Tricyclic; Child; Digoxin; Drug Administration Schedule; Drug Prescriptions; Humans; Kidney; Kinetics; Middle Aged; Nitrofurantoin; Pharmaceutical Preparations; Phenytoin; Sulfamethoxazole; Sulfonamides; Sweden; Tetracyclines; Trimethoprim	1978
Letter: Potentiations of warfarin by co-trimoxazole. British medical journal, 1975, Jun-21, Volume: 2, Issue:5972 Topics: Drug Synergism; Humans; Phenytoin; Prothrombin Time; Sulfamethoxazole; Trimethoprim; Warfarin	1975
Halothane-related hepatitis. A clinical study of twenty-six cases. The Quarterly journal of medicine, 1975, Volume: 44, Issue:173 Topics: Adult; Aged; Anesthesia, General; Bilirubin; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Glucose; Halothane; Humans; Jaundice; Male; Middle Aged; Neomycin; Penicillins; Phenothiazines; Phenytoin; Postoperative Complications; Sulfonamides; Tetracycline; Trimethoprim	1975
Effects of drugs on aminophylline elimination in rats. Arzneimittel-Forschung, 1988, Volume: 38, Issue:12 Topics: Aminophylline; Animals; Behavior, Animal; Carbamazepine; Cimetidine; Drug Combinations; Drug Interactions; Erythromycin; Female; Half-Life; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Rifampin; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1988
Widespread bullous fixed drug eruption mimicking toxic epidermal necrolysis. International journal of dermatology, 1988, Volume: 27, Issue:3 Topics: Adult; Anti-Infective Agents; Diagnosis, Differential; Drug Combinations; Female; Humans; Male; Phenytoin; Skin Diseases, Vesiculobullous; Stevens-Johnson Syndrome; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1988
Phenytoin toxicity and co-trimoxazole. Annals of internal medicine, 1985, Volume: 102, Issue:4 Topics: Child, Preschool; Drug Combinations; Drug Interactions; Female; Humans; Phenytoin; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1985
Drugs and folic acid absorption. Gastroenterology, 1972, Volume: 63, Issue:2 Topics: Animals; Contraceptives, Oral; Folic Acid; Folic Acid Deficiency; Intestinal Absorption; Methotrexate; Phenytoin; Pyrimethamine; Sulfasalazine; Trimethoprim	1972
[Lymphocyte transformation test in drug hypersensitivity]. Archiv fur dermatologische Forschung, 1972, Volume: 244 Topics: Ampicillin; Drug Hypersensitivity; Exanthema; Humans; Immunologic Techniques; Lymphocyte Activation; Penicillin G; Penicillins; Phenylbutazone; Phenytoin; Stevens-Johnson Syndrome; Sulfanilamides; Trimethoprim	1972
Blood lymphoblast proliferation in vivo in cutaneous drug hypersensitivity reactions. International archives of allergy and applied immunology, 1974, Volume: 46, Issue:2 Topics: Blood Cell Count; Carbamazepine; Chlorpromazine; Drug Hypersensitivity; Exanthema; Humans; Lymphocytes; Nitrofurantoin; Phenytoin; Prednisone; Stevens-Johnson Syndrome; Sulfonamides; Thymidine; Trimethoprim; Tritium; Urticaria	1974
Phenytoin intoxication and cotrimoxazole. The New Zealand medical journal, 1981, Sep-23, Volume: 94, Issue:692 Topics: Adult; Drug Combinations; Drug Interactions; Epilepsy; Humans; Male; Phenytoin; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1981
A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes. Clinical biochemistry, 2000, Volume: 33, Issue:7 Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Case-Control Studies; Cell Survival; Chemistry, Clinical; Child; Cohort Studies; Coloring Agents; Drug Hypersensitivity; Family Health; Female; HIV Seropositivity; Humans; Lamotrigine; Lymphocytes; Male; Mice; Microsomes, Liver; Middle Aged; Mitochondria; Phenobarbital; Phenytoin; Sensitivity and Specificity; Succinate Dehydrogenase; Sulfadiazine; Sulfamethoxazole; Sulfonamides; Tetrazolium Salts; Thiazoles; Time Factors; Triazines; Trimethoprim; Trypan Blue	2000
Effect of redox conditions on pharmaceutical loss during biological wastewater treatment using sequencing batch reactors. Journal of hazardous materials, 2015, Jan-23, Volume: 282 Topics: Aerobiosis; Anaerobiosis; Atenolol; Biological Oxygen Demand Analysis; Bioreactors; Chromatography, High Pressure Liquid; Cyclohexanols; Desvenlafaxine Succinate; Nitrogen; Oxidation-Reduction; Oxygen; Pharmaceutical Preparations; Phenytoin; Sewage; Solid Phase Extraction; Sulfamethoxazole; Tandem Mass Spectrometry; Trimethoprim; Waste Disposal, Fluid; Water Pollutants, Chemical	2015
Feasibility of amlodipine besylate, chloroquine phosphate, dapsone, phenytoin, pyridoxine hydrochloride, sulfadiazine, sulfasalazine, tetracycline hydrochloride, trimethoprim and zonisamide in SyrSpend(®) SF PH4 oral suspensions. Journal of pharmaceutical and biomedical analysis, 2016, Jan-25, Volume: 118 Topics: Administration, Oral; Amlodipine; Chloroquine; Chromatography, High Pressure Liquid; Dapsone; Drug Stability; Drug Storage; Feasibility Studies; Hydrogen-Ion Concentration; Isoxazoles; Phenytoin; Pyridoxine; Sulfadiazine; Sulfasalazine; Suspensions; Tetracycline; Trimethoprim; Zonisamide	2016