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trimethoprim and pefloxacin

trimethoprim has been researched along with pefloxacin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's1 (7.14)18.2507
2000's3 (21.43)29.6817
2010's5 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Cattoir, V; Nordmann, P; Poirel, L1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Gao, F; Huang, G; Xiao, J1
Boerema, JB1
de Micco, P; Gevaudan, MJ; Gulian, C; Lagier, P; Mallet, MN; Terriou, P1
Benbachir, M; el Filali, KM; el Mdaghri, N; Hajji, M; Himmich, H1
Dournon, E; Rajagopalan, P; Vildé, JL1
Hoogkamp-Korstanje, JA1
Abate, F; Balsotti, G; Cantini, L; Carlomagno, G; Cirese, E; Cosmi, EV; Di Renzo, GC; Indraccolo, R; La Sala, GB; Mearini, L; Minozzi, M; Monici Preti, PA; Scarpello, F1

Reviews

1 review(s) available for trimethoprim and pefloxacin

ArticleYear
Current scenario of tetrazole hybrids for antibacterial activity.
    European journal of medicinal chemistry, 2019, Dec-15, Volume: 184

    Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles

2019

Trials

2 trial(s) available for trimethoprim and pefloxacin

ArticleYear
Prospective randomized comparative trial of pefloxacin versus cotrimoxazole in the treatment of typhoid fever in adults.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1988, Volume: 7, Issue:3

    Topics: Adult; Drug Combinations; Female; Humans; Male; Norfloxacin; Paratyphoid Fever; Pefloxacin; Prospective Studies; Random Allocation; Salmonella paratyphi A; Salmonella paratyphi B; Salmonella typhi; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Typhoid Fever

1988
Efficacy and tolerability of brodimoprim at two different dosage schedules in the treatment of acute uncomplicated bacterial cystitis: comparative study vs. pefloxacin.
    European journal of obstetrics, gynecology, and reproductive biology, 1996, Volume: 64, Issue:2

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cystitis; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Pefloxacin; Treatment Outcome; Trimethoprim

1996

Other Studies

11 other study(ies) available for trimethoprim and pefloxacin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
New 4-quinolones in the treatment of urinary tract infections.
    Pharmaceutisch weekblad. Scientific edition, 1986, Feb-21, Volume: 8, Issue:1

    Topics: Anti-Infective Agents, Urinary; Ciprofloxacin; Drug Combinations; Humans; Male; Norfloxacin; Pefloxacin; Prostatitis; Pseudomonas Infections; Quinolines; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Bladder, Neurogenic; Urinary Tract Infections

1986
[Sensitivity of 7 mycobacterial species to new quinolones].
    Pathologie-biologie, 1988, Volume: 36, Issue:5

    Topics: Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Drug Combinations; Drug Synergism; Erythromycin; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Sulfamethoxazole; Thienamycins; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1988
Inhibition of Legionella pneumophila multiplication within human macrophages by antimicrobial agents.
    Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:5

    Topics: Anti-Bacterial Agents; Doxycycline; Drug Combinations; Erythromycin; Humans; Legionella; Macrophages; Microbial Sensitivity Tests; Netilmicin; Norfloxacin; Pefloxacin; Rifampin; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1986
Comparative in vitro activity of five quinoline derivatives and five other antimicrobial agents used in oral therapy.
    European journal of clinical microbiology, 1984, Volume: 3, Issue:4

    Topics: Administration, Oral; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Dose-Response Relationship, Drug; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Pefloxacin; Pseudomonas; Quinolines; Respiratory Tract Infections; Trimethoprim; Urinary Tract Infections

1984