Page last updated: 2024-08-16

trimethoprim and linezolid

trimethoprim has been researched along with linezolid in 27 studies

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	14 (51.85)	29.6817
2010's	11 (40.74)	24.3611
2020's	2 (7.41)	2.80

Authors

Authors	Studies
Hawser, S; Islam, K; Schneider, P	1
Frank, KL; Patel, R; Piper, KE; Reichert, EJ	1
Fiett, J; Gniadkowski, M; Grzesiowski, P; Hryniewicz, W; Izdebski, R; Sadowy, E	1
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S	1
Cheung, A; Götz, F; Herbert, S; Meehl, M	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Gentry, DR; Gwynn, MN; Holmes, DJ; McCloskey, L; Rittenhouse, SF; Scangarella, N; Shawar, R	1
Appelbaum, PC; Beachel, L; Caspers, P; Clark, C; Dewasse, B; Ednie, LM; Gaucher, B; Kosowska-Shick, K; Lin, G; McGhee, P; Mert, G; Shapiro, S; Smith, K	1
Fritsche, TR; Jones, RN; Sader, HS	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Bowker, KE; Caspers, P; Gaucher, B; MacGowan, AP	1
Kadlec, K; Schwarz, S	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Barrow, EW; Barrow, WW; Berlin, KD; Bourne, CR; Bourne, PC; Bunce, RA	1
Chan, JL; Cheung, GY; Joo, HS; Otto, M	1
Floyd, JL; Floyd, JT; Kumar, SH; Smith, KP; Varela, MF	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Koksch, B; Mikolajczak, DJ; Roth, C; Thota, CK	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Cavazos-Rocha, N; de la Luz Salazar-Cavazos, M; Vera-Cabrera, L; Waksman-de-Torres, N; Welsh-Lozano, O	1
Loffler, CA; Macdougall, C	1
Ariza, J; Cabellos, C; El Haj, C; Fontova, P; Gómez-Junyent, J; Lloberas, N; Murillo, O; Ribera, A; Tubau, F	1
Becker, K; Idelevich, EA; Kriegeskorte, A; Peters, G; Schleimer, N; von Eiff, C	1
Asari, S; Fukuyama, M; Hata, A; Hata, D; Iki, Y; Watanabe, K; Yoshioka, T	1

Reviews

1 review(s) available for trimethoprim and linezolid

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

26 other study(ies) available for trimethoprim and linezolid

Article	Year
Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria. Bioorganic & medicinal chemistry letters, 2003, Dec-01, Volume: 13, Issue:23 Topics: Animals; Drug Resistance, Bacterial; Folic Acid Antagonists; Lung; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Pyrimidines; Sepsis; Staphylococcus aureus; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Trimethoprim Resistance; Vancomycin	2003
In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3 Topics: Acetamides; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Biofilms; DNA, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Nafcillin; Oxazolidinones; Penicillin-Binding Proteins; Penicillins; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcal Infections; Staphylococcus; Tetracycline	2007
Clonal diversity and resistance mechanisms in tetracycline-nonsusceptible Streptococcus pneumoniae isolates in Poland. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Bacterial Proteins; Cell Lineage; DNA Transposable Elements; Genetic Variation; Poland; Streptococcus pneumoniae; Tetracycline; Tetracycline Resistance	2007
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen	2007
Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8 Topics: Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Bacterial Proteins; Gene Expression Regulation, Bacterial; Humans; Microbial Sensitivity Tests; Polymyxin B; Signal Transduction; Staphylococcal Infections; Staphylococcus aureus; Vancomycin; Vancomycin Resistance	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:12 Topics: Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Bacterial Proteins; Bridged Bicyclo Compounds, Heterocyclic; Diterpenes; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Pleuromutilins; Polycyclic Compounds; Sequence Analysis, DNA; Staphylococcus aureus	2008
Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Folic Acid Antagonists; Microbial Sensitivity Tests; Phthalazines; Staphylococcus aureus; Staphylococcus epidermidis; Tetrahydrofolate Dehydrogenase	2009
Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5 Topics: Anti-Bacterial Agents; Enterococcus faecalis; Europe; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Hospitalization; Humans; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pyrimidines; Staphylococcus aureus; Streptococcus; United States	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
In vitro activities of three new dihydrofolate reductase inhibitors against clinical isolates of gram-positive bacteria. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11 Topics: Folic Acid Antagonists; Gram-Positive Bacteria; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Phthalazines; Staphylococcus aureus; Streptococcus	2009
Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2 Topics: Animals; Anti-Bacterial Agents; Lincosamides; Macrolides; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Sequence Data; Multigene Family; Plasmids; Streptogramin B; Swine; Tetracycline Resistance; Trimethoprim	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9 Topics: Anti-Bacterial Agents; Enzyme Inhibitors; Inhibitory Concentration 50; Microbial Sensitivity Tests; Protein Structure, Secondary; Protein Structure, Tertiary; Staphylococcus aureus; Tetrahydrofolate Dehydrogenase	2010
Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11 Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Cytotoxins; Methicillin-Resistant Staphylococcus aureus; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Trans-Activators; Virulence	2010
LmrS is a multidrug efflux pump of the major facilitator superfamily from Staphylococcus aureus. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12 Topics: Amino Acid Sequence; Bacterial Proteins; Chloramphenicol; Drug Resistance, Multiple, Bacterial; Ethidium; Membrane Transport Proteins; Microbial Sensitivity Tests; Molecular Sequence Data; Onium Compounds; Organophosphorus Compounds; Phylogeny; Sequence Homology, Amino Acid; Sodium Dodecyl Sulfate; Staphylococcus aureus; Trimethoprim; Vancomycin	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Enhancing Antimicrobial Peptide Potency through Multivalent Presentation on Coiled-Coil Nanofibrils. ACS medicinal chemistry letters, 2021, Jan-14, Volume: 12, Issue:1 Topics:	2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Simultaneous determination and validation of antimicrobials in plasma and tissue of actinomycetoma by high-performance liquid chromatography with diode array and fluorescence detection. Journal of pharmaceutical and biomedical analysis, 2007, Apr-11, Volume: 43, Issue:5 Topics: Acetamides; Acetonitriles; Amoxicillin; Animals; Anti-Bacterial Agents; Buffers; Chemical Precipitation; Chromatography, High Pressure Liquid; Drug Stability; Fluoroquinolones; Freezing; Hydrogen-Ion Concentration; Linezolid; Mice; Mycetoma; Oxazolidinones; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Sulfamethoxazole; Time Factors; Trimethoprim; Water	2007
Update on prevalence and treatment of methicillin-resistant Staphylococcus aureus infections. Expert review of anti-infective therapy, 2007, Volume: 5, Issue:6 Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Cephalosporins; Clindamycin; Daptomycin; Doxycycline; Folic Acid Antagonists; Global Health; Glycopeptides; Humans; Linezolid; Lipoglycopeptides; Methicillin; Methicillin Resistance; Minocycline; Oxazolidinones; Prevalence; Staphylococcal Infections; Staphylococcus aureus; Sulfamethoxazole; Teicoplanin; Tigecycline; Trimethoprim; Vancomycin	2007
Evaluation of linezolid or trimethoprim/sulfamethoxazole in combination with rifampicin as alternative oral treatments based on an in vitro pharmacodynamic model of staphylococcal biofilm. International journal of antimicrobial agents, 2018, Volume: 51, Issue:6 Topics: Anti-Bacterial Agents; Biofilms; Drug Combinations; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Prosthesis-Related Infections; Rifampin; Sulfamethizole; Trimethoprim	2018
Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactams; Daptomycin; Lincosamides; Linezolid; Microbial Sensitivity Tests; Staphylococcus aureus; Trimethoprim	2018
Successful Conservative Treatment of Mycotic Pulmonary Artery Aneurysms Caused by MRSA Bacteremia. Pediatrics, 2019, Volume: 144, Issue:5 Topics: Aneurysm, Infected; Anti-Bacterial Agents; Bacteremia; Clindamycin; Conservative Treatment; Drug Combinations; Drug Therapy, Combination; Echocardiography; Female; Heart Septal Defects, Ventricular; Humans; Infant; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pulmonary Artery; Radiography; Rifampin; Staphylococcal Infections; Sulfamethizole; Trimethoprim	2019