Page last updated: 2024-08-16

trimethoprim and levoleucovorin

trimethoprim has been researched along with levoleucovorin in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199023 (76.67)18.7374
1990's6 (20.00)18.2507
2000's1 (3.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lietman, PS; Rogers, HJ1
Bersch, N; Golde, DW; Quan, SG1
Rollo, IM1
O'Grady, F1
Richards, RM; Taylor, RB; Xing, DK1
Laizure, SC; Lancaster, DJ; Palte, S; Stein, DS; Stevens, RC; Terry, D; Weems, JJ; Williams, CL1
Crosby, WH1
Bygbjerg, IC; Hørding, M; Lund, JT1
Davis, M; Gall, EP; Maricic, M1
D'Antonio, RG; Evans, ME; Johnson, DB; van Dellen, AF; Winn, RE1
Bjornson, BH; Harvey, JM; McIntyre, AP; Tauber, AI1
Morrison, JF; Stone, SR1
Hollander, H1
Heidt, PJ; Kieskamp, MJ; Timmermans, CP1
Schaberg, DR; Zervos, MJ1
Grunberg, E1
Navarro, J1
Gauldie, J; Hiebert, M; Hillcoat, BL; Marshall, L1
Clark, JM; Klein, WH; Lazar, JM; Lundquist, RE1
Pavillard, ER1
Kinzie, BJ; Taylor, JW1
Allistone, JC; Nunn, PP1
Campbell, CL; Hillman, RS; Rabinovitch, PS; Steinberg, SE1
Momparler, LF; Momparler, RL; Rivard, GE1
Kobrinsky, NL; Ramsay, NK1
Akil, B; Baughman, R; Boylen, CT; Davis, R; Frame, P; Hughlett, C; Nichols, L; Sattler, FR; Shelton, B; Weiss, W1
Assaraf, YG; Slotky, JI1
Korraa, H; Saadeh, C1
Asencio Marchante, R; Lissen Otero, E1

Reviews

2 review(s) available for trimethoprim and levoleucovorin

ArticleYear
The effect of trimethoprim on the activity of sulfonamides and antibiotics in experimental infections.
    The Journal of infectious diseases, 1973, Volume: 128

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Bacterial Infections; Drug Synergism; Escherichia coli Infections; Haemophilus Infections; Klebsiella Infections; Leucovorin; Mice; Microbial Sensitivity Tests; Pneumococcal Infections; Proteus Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Salmonella Infections; Staphylococcal Infections; Sulfonamides; Thymidine; Trimethoprim

1973
Options in the management of pneumonia caused by Pneumocystis carinii in patients with acquired immune deficiency syndrome and intolerance to trimethoprim/sulfamethoxazole.
    Southern medical journal, 1996, Volume: 89, Issue:3

    Topics: Adrenal Cortex Hormones; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Agents; Atovaquone; Clindamycin; Dapsone; Drug Combinations; Drug Hypersensitivity; Drug Resistance, Microbial; Humans; Leucovorin; Naphthoquinones; Pentamidine; Pneumonia, Pneumocystis; Primaquine; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate

1996

Trials

2 trial(s) available for trimethoprim and levoleucovorin

ArticleYear
Use of low-dose trimethoprim-sulfamethoxazole thrice weekly for primary and secondary prophylaxis of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected patients.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:9

    Topics: Adult; Chromatography, High Pressure Liquid; Complement C4; Drug Administration Schedule; Female; HIV Infections; Humans; Leucovorin; Male; Pneumonia, Pneumocystis; Prospective Studies; Sulfamethoxazole; Trimethoprim; Zidovudine

1991
Trimetrexate with leucovorin versus trimethoprim-sulfamethoxazole for moderate to severe episodes of Pneumocystis carinii pneumonia in patients with AIDS: a prospective, controlled multicenter investigation of the AIDS Clinical Trials Group Protocol 029/0
    The Journal of infectious diseases, 1994, Volume: 170, Issue:1

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Child; Clinical Protocols; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Middle Aged; Multicenter Studies as Topic; Pneumonia, Pneumocystis; Prospective Studies; Sulfamethoxazole; Treatment Outcome; Trimethoprim; Trimetrexate

1994

Other Studies

26 other study(ies) available for trimethoprim and levoleucovorin

ArticleYear
The in vitro effect of trimethoprim on blastogenic transformation of human peripheral blood lymphocytes.
    Biochemical pharmacology, 1977, Sep-01, Volume: 26, Issue:17

    Topics: Autoradiography; Cells, Cultured; Concanavalin A; Deoxyuridine; Folic Acid; Formates; Humans; In Vitro Techniques; Leucine; Leucovorin; Lymphocyte Activation; Lymphocytes; Thymidine; Time Factors; Trimethoprim; Uridine

1977
Trimethoprim and sulphamethoxazole inhibition of haematopoiesis in vitro.
    British journal of haematology, 1978, Volume: 40, Issue:3

    Topics: Adult; Animals; Colony-Forming Units Assay; Depression, Chemical; Dose-Response Relationship, Drug; Erythropoiesis; Granulocytes; Hematopoiesis; Humans; Leucovorin; Mice; Sulfamethoxazole; Trimethoprim

1978
Antiplasmodial efficacy of 2,4--diaminopyrimidine0sylfonamide combinations, especially against chloroquine-resistant malaria.
    Canadian Medical Association journal, 1975, Jun-14, Volume: 112, Issue:13 Spec No

    Topics: Antimalarials; Chloroquine; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Enterococcus faecalis; Folic Acid; Folic Acid Antagonists; History, 20th Century; Humans; Lacticaseibacillus casei; Leucovorin; Malaria; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Pyrimidines; Sulfalene; Sulfonamides; Trimethoprim

1975
Trimethoprim-sulfamethoxazole: A reappraisal.
    Canadian Medical Association journal, 1975, Jun-14, Volume: 112, Issue:13 Spec No

    Topics: Bacteria; Bacterial Infections; Drug Combinations; Drug Resistance, Microbial; Drug Synergism; Folic Acid; Folic Acid Deficiency; Humans; Leucovorin; Sulfamethoxazole; Trimethoprim

1975
An evaluation of the antibacterial activities of combinations of sulfonamides, trimethoprim, dibromopropamidine, and silver nitrate compared with their uptakes by selected bacteria.
    Journal of pharmaceutical sciences, 1991, Volume: 80, Issue:9

    Topics: Bacteria; Benzamidines; Drug Combinations; Drug Synergism; Enterobacter cloacae; Leucovorin; Pseudomonas aeruginosa; Silver Nitrate; Staphylococcus aureus; Sulfonamides; Trimethoprim

1991
Megaloblastic pancytopenia associated with dapsone and trimethoprim treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome.
    Archives of internal medicine, 1990, Volume: 150, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Anemia, Macrocytic; Anemia, Megaloblastic; Dapsone; Humans; Leucovorin; Pneumonia, Pneumocystis; Trimethoprim; Vitamin B 12 Deficiency

1990
Effect of folic and folinic acid on cytopenia occurring during co-trimoxazole treatment of Pneumocystis carinii pneumonia.
    Scandinavian journal of infectious diseases, 1988, Volume: 20, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Anemia; Drug Combinations; Folic Acid; Hematologic Diseases; Humans; Leucovorin; Leukopenia; Pneumonia, Pneumocystis; Prospective Studies; Sulfamethoxazole; Thrombocytopenia; Time Factors; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1988
Megaloblastic pancytopenia in a patient receiving concurrent methotrexate and trimethoprim-sulfamethoxazole treatment.
    Arthritis and rheumatism, 1986, Volume: 29, Issue:1

    Topics: Abscess; Breast Diseases; Cough; Drug Combinations; Erythrocytes; Erythrocytes, Abnormal; Female; Folic Acid; Folic Acid Antagonists; Humans; Leucovorin; Megaloblasts; Methotrexate; Middle Aged; Neutrophils; Pancytopenia; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1986
Effect of folinic acid on the capacity of trimethoprim-sulfamethoxazole to prevent and treat Pneumocystis carinii pneumonia in rats.
    Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:2

    Topics: Animals; Dexamethasone; Drug Combinations; Drug Interactions; Immunosuppression Therapy; Leucovorin; Leukopenia; Male; Pneumocystis; Pneumonia, Pneumocystis; Random Allocation; Rats; Rats, Inbred Strains; Sulfamethoxazole; Tetracycline; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1986
Studies of the effects of trimethoprim and sulfamethoxazole on human granulopoiesis.
    American journal of hematology, 1986, Volume: 23, Issue:1

    Topics: Adult; Colony-Forming Units Assay; Depression, Chemical; Drug Combinations; Female; Granulocytes; Hematopoiesis; Humans; Leucovorin; Leukocyte Count; Male; Neutrophils; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1986
Mechanism of inhibition of dihydrofolate reductases from bacterial and vertebrate sources by various classes of folate analogues.
    Biochimica et biophysica acta, 1986, Feb-14, Volume: 869, Issue:3

    Topics: Animals; Binding, Competitive; Chickens; Escherichia coli; Folic Acid; Folic Acid Antagonists; Leucovorin; Liver; Methotrexate; NADP; Pteridines; Pyrimethamine; Tetrahydrofolate Dehydrogenase; Triazines; Trimethoprim

1986
Leukopenia, trimethoprim-sulfamethoxazole, and folinic acid.
    Annals of internal medicine, 1985, Volume: 102, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Drug Combinations; Humans; Leucovorin; Leukopenia; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1985
Trimethoprim-sulfamethoxazole and folinic acid.
    Annals of internal medicine, 1985, Volume: 102, Issue:2

    Topics: Drug Combinations; Hematologic Diseases; Humans; Leucovorin; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1985
The influence of calcium leucovorin on the co-trimoxazole induced inhibition of leukocyte regeneration after bone marrow transplantation in mice.
    Progress in clinical and biological research, 1985, Volume: 181

    Topics: Animals; Anti-Bacterial Agents; Bone Marrow Transplantation; Calcium; Drug Combinations; Leucovorin; Leukocytes; Male; Mice; Mice, Inbred Strains; Regeneration; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1985
Reversal of the in vitro susceptibility of enterococci to trimethoprim-sulfamethoxazole by folinic acid.
    Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:3

    Topics: Drug Combinations; Enterococcus faecalis; In Vitro Techniques; Leucovorin; Microbial Sensitivity Tests; Sulfamethoxazole; Trimethoprim

1985
[Biological tolerance of the trimethoprim-sulfamethoxazole combination in pediatrics. Its influence on serum folic and folinic acid levels].
    Therapeutique (La Semaine des hopitaux), 1972, Volume: 48, Issue:10

    Topics: Adolescent; Age Factors; Anti-Infective Agents; Bacterial Infections; Child; Child, Preschool; Drug Eruptions; Drug Tolerance; Evaluation Studies as Topic; Female; Folic Acid; Folic Acid Antagonists; Humans; Infant; Infant, Newborn; Leucovorin; Male; Pyrimidines; Sulfamethoxazole; Trimethoprim; Vomiting

1972
Stabilization of dihydrofolate reductase by inhibitors in vivo and in vitro.
    Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186

    Topics: Animals; Biodegradation, Environmental; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chromatography, Gel; Cycloheximide; Drug Stability; Electrophoresis; Enzyme Activation; Folic Acid Antagonists; Humans; Leucovorin; Leukemia L1210; Liver Neoplasms; Methotrexate; Mice; Rats; Tetrahydrofolate Dehydrogenase; Triamterene; Trimethoprim

1971
Translation of satellite tobacco necrosis virus ribonucleic acid. II. Initiation of in vitro translation in procaryotic and eucaryotic systems.
    Biochemistry, 1972, May-23, Volume: 11, Issue:11

    Topics: Alanine; Amino Acids; Bacterial Proteins; Carbon Isotopes; Cell Nucleus; Cell-Free System; Escherichia coli; Formates; Leucovorin; Methionine; NAD; Nicotiana; Peptide Biosynthesis; Peptide Chain Initiation, Translational; Peptide Hydrolases; Plant Proteins; Plant Viruses; Plants; Plants, Toxic; RNA, Messenger; RNA, Transfer; RNA, Viral; Trimethoprim; Triticum; Tritium

1972
Treatment of nocardial infection with trimethoprim-sulphamethoxazole.
    The Medical journal of Australia, 1973, Jun-30, Volume: 1, Issue:2

    Topics: Adult; Aged; Anti-Bacterial Agents; Drug Combinations; Drug Synergism; Female; Folic Acid Antagonists; Humans; Leucovorin; Male; Microbial Sensitivity Tests; Middle Aged; Nocardia asteroides; Nocardia Infections; Pyrimidines; Sulfamethoxazole; Trimethoprim

1973
Trimethoprim and folinic acid.
    Annals of internal medicine, 1984, Volume: 101, Issue:4

    Topics: Drug Therapy, Combination; Hematologic Diseases; Humans; Leucovorin; Trimethoprim

1984
Resistance to trimethoprim-sulfamethoxazole in the treatment of Pneumocystis carinii pneumonia. Implication of folinic acid.
    Chest, 1984, Volume: 86, Issue:1

    Topics: Drug Combinations; Drug Resistance; Humans; Leucovorin; Male; Middle Aged; Pneumonia, Pneumocystis; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1984
The effect of trimethoprim/sulfamethoxazole on Friend erythroleukemia cells.
    Blood, 1980, Volume: 55, Issue:3

    Topics: Cell Transformation, Neoplastic; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Erythrocyte Volume; Friend murine leukemia virus; Leucovorin; Leukemia, Erythroblastic, Acute; Megaloblasts; Sulfamethoxazole; Trimethoprim

1980
Effects of trimethoprim on leukaemic cells in vitro.
    British journal of haematology, 1981, Volume: 47, Issue:2

    Topics: Animals; Cell Survival; Cells, Cultured; Child; Deoxyuridine; Dose-Response Relationship, Drug; Humans; Leucovorin; Leukemia L1210; Leukemia, Lymphoid; Mice; Sulfamethoxazole; Trimethoprim

1981
Acute megaloblastic anemia induced by high-dose trimethoprim-sulfamethoxazole.
    Annals of internal medicine, 1981, Volume: 94, Issue:6

    Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Drug Combinations; Female; Humans; Leucovorin; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1981
Characterization of a lipophilic antifolate resistance provoked by treatment of mammalian cells with the antiparasitic agent pyrimethamine.
    The Journal of biological chemistry, 1993, Feb-25, Volume: 268, Issue:6

    Topics: Animals; Cell Survival; CHO Cells; Cricetinae; Drug Resistance; Flow Cytometry; Folic Acid Antagonists; Leucovorin; Pyrimethamine; RNA, Messenger; Tetrahydrofolate Dehydrogenase; Trimethoprim

1993
[Secondary prevention of opportunistic infections in HIV-infected patients].
    Revista clinica espanola, 2001, Volume: 201, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antiprotozoal Agents; Antitubercular Agents; Antiviral Agents; Clarithromycin; Cytomegalovirus Infections; Drug Therapy, Combination; Ethambutol; Ganciclovir; Humans; Leucovorin; Mycobacterium avium-intracellulare Infection; Pneumonia, Pneumocystis; Pyrimethamine; Recurrence; Rifabutin; Sulfadiazine; Sulfamethoxazole; Toxoplasmosis; Trimethoprim

2001