trimethoprim has been researched along with dactinomycin in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dias, CB; Hansch, C; Khwaja, TA; Pentecost, S; Selassie, CD | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bavari, S; Bowlin, TL; Houseweart, C; Moir, DT; Opperman, TJ; Panchal, RG; Peet, NP; Williams, JD | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Lindner, A; Rudas, B; Selzer, H | 1 |
| Schulz, R | 1 |
| Jones, EE; Weyter, FW; Wozny, ME | 1 |
1 review(s) available for trimethoprim and dactinomycin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
11 other study(ies) available for trimethoprim and dactinomycin
| Article | Year |
|---|---|
Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chickens; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia L5178; Leukemia, Experimental; Mathematics; Methotrexate; Mice; Structure-Activity Relationship; Triazines | 1984 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR.
Topics: Bacterial Proteins; Drug Resistance, Bacterial; Indoles; Microbial Sensitivity Tests; Mutation; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcus aureus; Structure-Activity Relationship; Substrate Specificity | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
[Comparative studies on the effect of antibacterial substances on inflammation and wound healing in rats].
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Carrageenan; Dactinomycin; Disease Models, Animal; Edema; Folic Acid Antagonists; Granulation Tissue; Leucomycins; Neomycin; Pyrimidines; Rats; Trimethoprim; Wound Healing | 1972 |
Rat folic acid reductase activity during the perinatal period, in newborns, and after trimethoprim administration.
Topics: Administration, Oral; Animals; Animals, Newborn; Anti-Infective Agents; Dactinomycin; Female; Fetus; Folic Acid Antagonists; Kidney; Liver; Male; Pregnancy; Pregnancy, Animal; Puromycin; Pyrimidines; Rats; Spectrophotometry; Tetrahydrofolate Dehydrogenase; Trimethoprim | 1972 |
Inhibition of transcription and translation of an arginine-induced and rifampin-induced acetylornithine delta-transaminase of Escherichia coli.
Topics: Acetamides; Amidohydrolases; Arginine; Carbon Radioisotopes; Cell-Free System; Chloramphenicol; Dactinomycin; Enzyme Induction; Enzyme Repression; Escherichia coli; Kinetics; Leucine; Methionine; Ornithine; Peptide Chain Elongation, Translational; Phenylalanine; Protein Biosynthesis; Rifampin; Time Factors; Transaminases; Transcription, Genetic; Trimethoprim; Tritium; Uridine | 1973 |