Compounds > trimethoprim
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trimethoprim and clavulanic acid

trimethoprim has been researched along with clavulanic acid in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's1 (5.56)18.2507
2000's7 (38.89)29.6817
2010's5 (27.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Bonnet, R; Caniça, M; Ferreira, E; Manageiro, V; Mendonça, N; Robin, F; Salgado, MJ1
Lombardo, F; Obach, RS; Waters, NJ1
Evenhuis, J; Griffin, M; Harbottle, H; McDermott, PF; Miller, RA; Welch, TJ; White, DG; Wise, D1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Bonnet, R; Casin, I; Doublet, B; Fabre, L; Le Fleche, A; Robin, F; Weill, FX1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chapin, KC; Doern, GV1
Shurin, PA; Van Hare, GF1
Lapointe, JR; Lavallée, C1
Schmid, GP1
Karachalios, GN1
Wortman, PD1
Babić-Erceg, A; Barisić, Z; Borzić, E; Carev, M; Kaliterna, V; Zoranić, V1
Dance, D1

Reviews

2 review(s) available for trimethoprim and clavulanic acid

ArticleYear
The treatment of chancroid.
    JAMA, 1986, Apr-04, Volume: 255, Issue:13

    Topics: Amoxicillin; Anti-Bacterial Agents; Ceftriaxone; Chancroid; Clavulanic Acid; Clavulanic Acids; Clinical Trials as Topic; Drug Combinations; Erythromycin; Haemophilus ducreyi; Humans; Penicillin Resistance; Rifampin; Sulfonamides; Trimethoprim

1986
Treatment and prophylaxis of melioidosis.
    International journal of antimicrobial agents, 2014, Volume: 43, Issue:4

    Topics: Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Burkholderia pseudomallei; Carbapenems; Ceftazidime; Clavulanic Acid; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Infusions, Parenteral; Melioidosis; Sulfamethoxazole; Trimethoprim

2014

Trials

2 trial(s) available for trimethoprim and clavulanic acid

ArticleYear
The treatment of chancroid.
    JAMA, 1986, Apr-04, Volume: 255, Issue:13

    Topics: Amoxicillin; Anti-Bacterial Agents; Ceftriaxone; Chancroid; Clavulanic Acid; Clavulanic Acids; Clinical Trials as Topic; Drug Combinations; Erythromycin; Haemophilus ducreyi; Humans; Penicillin Resistance; Rifampin; Sulfonamides; Trimethoprim

1986
Randomized comparative study of amoxicillin-clavulanic acid and co-trimoxazole in the treatment of acute urinary tract infections in adults.
    Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Amoxicillin; Anti-Infective Agents, Urinary; Clavulanic Acid; Clavulanic Acids; Clinical Trials as Topic; Drug Combinations; Female; Humans; Male; Middle Aged; Random Allocation; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections

1985

Other Studies

15 other study(ies) available for trimethoprim and clavulanic acid

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5

    Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Arginine; Aztreonam; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Computer Simulation; Imipenem; Isoelectric Focusing; Kinetics; Klebsiella pneumoniae; Lysine; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Penicillins; Protein Conformation; Protein Structure, Tertiary

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
IncA/C plasmid-mediated florfenicol resistance in the catfish pathogen Edwardsiella ictaluri.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Catfishes; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Edwardsiella ictaluri; Enterobacteriaceae Infections; Fish Diseases; Molecular Sequence Data; Plasmids; Thiamphenicol

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Molecular and biochemical characterization of the natural chromosome-encoded class A beta-lactamase from Pseudomonas luteola.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Catheters, Indwelling; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Genetic Variation; Isoelectric Focusing; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Pseudomonas; Pseudomonas Infections; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Susceptibility of Haemophilus influenzae to amoxicillin/clavulanic acid, erythromycin, cefaclor, and trimethoprim/sulfamethoxazole.
    Diagnostic microbiology and infectious disease, 1986, Volume: 4, Issue:1

    Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Erythromycin; Haemophilus influenzae; Humans; Infant; Microbial Sensitivity Tests; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1986
Therapy of acute otitis media caused by Branhamella catarrhalis. Preliminary report.
    Drugs, 1986, Volume: 31 Suppl 3

    Topics: Amoxicillin; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Humans; Neisseriaceae; Otitis Media; Penicillin Resistance; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1986
Antibiotic interaction of amoxycillin and clavulanic acid against 132 beta-lactamase positive Haemophilus isolates: a comparison with some other oral agents.
    The Journal of antimicrobial chemotherapy, 1987, Volume: 19, Issue:1

    Topics: Amoxicillin; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Synergism; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1987
Treatment of a Nocardia brasiliensis mycetoma with sulfamethoxazole and trimethoprim, amikacin, and amoxicillin and clavulanate.
    Archives of dermatology, 1993, Volume: 129, Issue:5

    Topics: Adult; Amikacin; Amoxicillin; Anti-Bacterial Agents; Clavulanic Acid; Clavulanic Acids; Humans; Male; Mycetoma; Nocardia Infections; Sulfamethoxazole; Trimethoprim

1993
Urinary tract infections in South Croatia: aetiology and antimicrobial resistance.
    International journal of antimicrobial agents, 2003, Volume: 22 Suppl 2

    Topics: Amoxicillin; Anti-Bacterial Agents; Bacterial Infections; Ceftibuten; Cephalosporins; Clavulanic Acid; Croatia; Drug Resistance, Bacterial; Escherichia coli; Gram-Negative Bacteria; Humans; Nitrofurantoin; Norfloxacin; Sulfamethoxazole; Trimethoprim; Urinary Tract Infections

2003