Page last updated: 2024-08-16

trimethoprim and cb 3717

trimethoprim has been researched along with cb 3717 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elzein, E; Gangjee, A; Kisliuk, RL; McGuire, JJ; Queener, SF; Vidwans, A1
Gangjee, A; Haile, WH; Kisliuk, RL; McGuire, JJ; Sobrero, G; Yu, J1
Gangjee, A; Kisliuk, RL; Li, W; Yang, J1
Cody, V; Gangjee, A; Kisliuk, RL; Li, W; Makin, J; Pace, J; Piraino, J1
Boesche, M; Crowther, GJ; Dasari, KS; Drewes, G; El Bakkouri, M; Fox, AM; Ghidelli-Disse, S; He, P; Hillesland, HK; Hui, R; Jones, JC; Keyloun, KR; Krahn, MM; Lafuente-Monasterio, MJ; Leonard, SE; Leroy, D; Maly, DJ; Mo, JS; Ojo, KK; Reid, MC; Rivas, KL; Van Voorhis, WC1

Other Studies

5 other study(ies) available for trimethoprim and cb 3717

ArticleYear
Synthesis, antifolate, and antitumor activities of classical and nonclassical 2-amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines.
    Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Survival; Drug Design; Folic Acid Antagonists; Glutamates; Guanine; Humans; Liver; Models, Molecular; Molecular Conformation; Pemetrexed; Pneumocystis; Pyrimidines; Pyrroles; Rats; Recombinant Proteins; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Toxoplasma; Tumor Cells, Cultured

2001
Design, synthesis, and biological activities of classical N-[4-[2-(2-amino-4-ethylpyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid and its 6-methyl derivative as potential dual inhibitors of thymidylate synthase and dihydrofolate reductase and
    Journal of medicinal chemistry, 2003, Feb-13, Volume: 46, Issue:4

    Topics: Antineoplastic Agents; Cell Division; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Escherichia coli; Folic Acid Antagonists; Glutamic Acid; Humans; Lacticaseibacillus casei; Peptide Synthases; Pyrimidines; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tumor Cells, Cultured

2003
Design, synthesis, and biological evaluation of classical and nonclassical 2-amino-4-oxo-5-substituted-6-methylpyrrolo[3,2-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors.
    Journal of medicinal chemistry, 2008, Jan-10, Volume: 51, Issue:1

    Topics: Animals; Antineoplastic Agents; Drug Design; Escherichia coli; Folic Acid Antagonists; Humans; Models, Molecular; Pyrimidines; Pyrroles; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Toxoplasma

2008
Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Folic Acid Antagonists; Humans; Pyrimidines; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Toxoplasma

2009
Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Antimalarials; Calcium; Cell Line, Tumor; Hep G2 Cells; Humans; Malaria, Falciparum; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Plasmodium falciparum; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protozoan Proteins

2016