trimethoprim has been researched along with aditoprim in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (25.00) | 18.7374 |
| 1990's | 12 (42.86) | 18.2507 |
| 2000's | 1 (3.57) | 29.6817 |
| 2010's | 7 (25.00) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Richards, WG; So, SS | 1 |
| Debnath, G; Fang, ZX; Hansch, C; Kaufman, BT; Klein, TE; Langridge, R; Li, RL; Selassie, CD | 1 |
| Fang, ZX; Hansch, C; Kaufman, BT; Klein, T; Langridge, R; Li, RL; Selassie, CD | 1 |
| Loukas, YL | 1 |
| Graser, T; Lohuis, JA; Ludwig, B; Rehm, WF; Rohde, E; Schneider, B; Sutter, HM; van Miert, AS; van Werven, T; Wanner, M | 1 |
| Müller, P; Riond, JL; Wanner, M | 1 |
| Jordan, JC; Ludwig, B; Rehm, WF; von Fellenberg, RL | 1 |
| Mengelers, MJ; van Klingeren, B; van Miert, AS | 1 |
| Jordan, JC; Klatt, P; Ludwig, B | 1 |
| Knoppert, NW; Korstanje, C; Nijmeijer, SM; van Duin, CT; van Gogh, H; van Miert, AS | 1 |
| Keller, M; Then, RL | 1 |
| Haenni, K; Jordan, JC; Ludwig, B; Rehm, WF | 1 |
| Ascalone, V; Jordan, JC; Ludwig, BM | 1 |
| Ashfaq, MK; Iqbal, MP; Mahboobali, N; Niazi, SK | 1 |
| Ashfaq, MK; Iqbal, MP; Khawaja, KN; Mahboobali, M; Niazi, SK | 1 |
| Riond, JL; Sutter, HM; Wanner, M | 1 |
| Alvinerie, M; Eeckhoutte, C; Galtier, P; Sutra, JF; van 't Klooster, GA; van Miert, AS | 1 |
| Engeli, J; Riond, JL; Wanner, M | 1 |
| Iqbal, MP; Mehboobali, N; Niazi, SK; Zaidi, AA | 1 |
| Hoogenboom, LA; Kleter, GA; Kuiper, HA; Mengelers, MJ; Van Miert, AS | 1 |
| Chen, D; Cheng, G; Huang, L; Ihsan, A; Liu, Q; Liu, Z; Pan, Y; Tan, Z; Tao, Y; Wang, X; Yuan, Z | 1 |
| Awais, I; Chen, D; Cheng, G; Huang, L; Liu, Z; Pan, Y; Tan, Z; Wang, X; Yuan, Z | 1 |
| Ahmad, I; Chen, D; Huang, L; Klímová, B; Kuča, K; Liu, Z; Pan, Y; Tao, Y; Wan, D; Wang, L; Wu, Q; Xie, S; Yuan, Z | 1 |
| Huang, L; Pan, Y; Wang, L; Wu, Q; Xie, S; Yuan, Z | 1 |
| Chen, D; Cheng, G; Hao, H; Huang, L; Liu, Z; Pan, Y; Wang, L; Wang, Y; Xie, S; Xu, Y; Yuan, Z; Zhu, X | 1 |
| Ahmed, S; Chen, M; Han, X; Kong, D; Liu, Z; Pan, Y; Peng, D; Sheng, F; Tao, Y; Wang, Y; Yuan, Z | 1 |
| He, Z; Hu, M; Peng, W; Wang, L; Wei, D; Wu, C; Xie, M; Zhang, M; Zhang, Q | 1 |
| Huang, L; Pan, Y; Tao, Y; Wang, L; Wang, X; Wang, Y; Zhai, Q; Zhang, Y; Zheng, Y | 1 |
28 other study(ies) available for trimethoprim and aditoprim
| Article | Year |
|---|---|
Application of neural networks: quantitative structure-activity relationships of the derivatives of 2,4-diamino-5-(substituted-benzyl)pyrimidines as DHFR inhibitors.
Topics: Drug Design; Folic Acid Antagonists; Neural Networks, Computer; Pyrimidines; Regression Analysis; Structure-Activity Relationship | 1992 |
On the structure selectivity problem in drug design. A comparative study of benzylpyrimidine inhibition of vertebrate and bacterial dihydrofolate reductase via molecular graphics and quantitative structure-activity relationships.
Topics: Animals; Chemical Phenomena; Chemistry; Chickens; Drug Design; Folic Acid Antagonists; Lacticaseibacillus casei; Liver; Pyrimidines; Structure-Activity Relationship; X-Ray Diffraction | 1989 |
Inhibition of chicken liver dihydrofolate reductase by 5-(substituted benzyl)-2,4-diaminopyrimidines. A quantitative structure-activity relationship and graphics analysis.
Topics: Animals; Chickens; Crystallography; Enzyme Inhibitors; Folic Acid Antagonists; Liver; Mathematics; Models, Molecular; Pyrimidines; Structure-Activity Relationship; Trimethoprim; X-Ray Diffraction | 1986 |
Adaptive neuro-fuzzy inference system: an instant and architecture-free predictor for improved QSAR studies.
Topics: Algorithms; Folic Acid Antagonists; Multivariate Analysis; Pyrimidines; Quantitative Structure-Activity Relationship; Regression Analysis; Tetrahydrofolate Dehydrogenase | 2001 |
Effects of endotoxin-induced mastitis on the pharmacokinetic properties of aditoprim in dairy cows.
Topics: Animals; Cattle; Endotoxins; Female; Iron; Leukocyte Count; Mastitis, Bovine; Trimethoprim; Zinc | 1992 |
The influence of age on the pharmacokinetics of aditoprim in pigs after intravenous and oral administration.
Topics: Administration, Oral; Aging; Animals; Injections, Intravenous; Male; Swine; Trimethoprim | 1992 |
Plasma disposition and tolerance of aditoprim in horses after single intravenous injection.
Topics: Animals; Drug Tolerance; Female; Folic Acid Antagonists; Horses; Male; Trimethoprim | 1990 |
In vitro susceptibility of some porcine respiratory tract pathogens to aditoprim, trimethoprim, sulfadimethoxine, sulfamethoxazole, and combinations of these agents.
Topics: Actinobacillus; Animals; Anti-Bacterial Agents; Bordetella; Drug Resistance, Microbial; Drug Therapy, Combination; Microbial Sensitivity Tests; Pasteurella; Sulfadimethoxine; Sulfamethoxazole; Swine; Trimethoprim; Trimethoprim Resistance | 1990 |
Pharmacokinetics of aditoprim, a new long-acting dihydrofolate reductase inhibitor, in heifers.
Topics: Animals; Cattle; Drug Combinations; Female; Folic Acid Antagonists; Kinetics; Sulfamerazine; Sulfamethazine; Trimethoprim | 1987 |
Some pharmacokinetic data of aditoprim and trimethoprim in healthy and tick-borne fever infected dwarf goats.
Topics: Administration, Oral; Animals; Ehrlichia; Goats; Injections, Intravenous; Rickettsiaceae Infections; Trimethoprim | 1988 |
Properties of aditoprim, a new antibacterial dihydrofolate reductase inhibitor.
Topics: Animals; Bacteria; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Humans; Trimethoprim | 1988 |
Pharmacokinetics of aditoprim, a dihydrofolate reductase inhibitor, in sheep.
Topics: Animals; Folic Acid Antagonists; Half-Life; Kinetics; Male; Regression Analysis; Sheep; Trimethoprim | 1987 |
Determination of aditoprim, a new dihydrofolate reductase inhibitor, in the plasma of cows and pigs.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Drug Stability; Folic Acid Antagonists; Quality Control; Species Specificity; Spectrophotometry, Ultraviolet; Swine; Trimethoprim | 1986 |
Pharmacokinetics of aditoprim in normal and febrile sheep.
Topics: Animals; Bacterial Infections; Disease Models, Animal; Enzyme Inhibitors; Fever; Rectum; Sheep; Time Factors; Trimethoprim | 1995 |
Pharmacokinetics of aditoprim and trimethoprim in buffalo calves.
Topics: Animals; Cattle; Female; Metabolic Clearance Rate; Models, Biological; Trimethoprim | 1994 |
Comparative pharmacokinetics of aditoprim in milk-fed and conventionally fed calves of different ages.
Topics: Administration, Oral; Aging; Animal Feed; Animals; Cattle; Injections, Intravenous; Male; Milk; Trimethoprim | 1993 |
Determination of aditoprim and its oxidative metabolites in plasma and microsomal incubation mixtures by high-performance liquid chromatography.
Topics: Animals; Biotransformation; Cattle; Chromatography, High Pressure Liquid; Dogs; Folic Acid Antagonists; Horses; Indicators and Reagents; Microsomes, Liver; Oxidation-Reduction; Quality Control; Rabbits; Rats; Reference Standards; Sheep; Spectrophotometry, Ultraviolet; Swine; Trimethoprim | 1993 |
Research note: pharmacokinetics of aditoprim in turkeys after intravenous and oral administration.
Topics: Administration, Oral; Animals; Female; Folic Acid Antagonists; Injections, Intravenous; Trimethoprim; Turkeys | 1993 |
Disposition kinetics of aditoprim in two monkeys in comparison to other mammalian species.
Topics: Animals; Computer Simulation; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Positive Bacteria; Half-Life; Injections, Intravenous; Macaca mulatta; Male; Species Specificity; Tetrahydrofolate Dehydrogenase; Trimethoprim | 1995 |
The biotransformation of sulfadimethoxine, sulfadimidine, sulfamethoxazole, trimethoprim and aditoprim by primary cultures of pig hepatocytes.
Topics: Acetylation; Animals; Anti-Infective Agents; Biotransformation; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Folic Acid Antagonists; Liver; Methylation; Pregnancy; Structure-Activity Relationship; Sulfadimethoxine; Sulfamethazine; Sulfamethoxazole; Swine; Trimethoprim | 1997 |
Safety assessment of aditoprim acute, subchronic toxicity and mutagenicity studies.
Topics: Animals; Body Weight; CHO Cells; Cricetulus; Diet; Dose-Response Relationship, Drug; Female; Kidney; Liver; Male; Mice; Micronucleus Tests; Mutagenicity Tests; No-Observed-Adverse-Effect Level; Organ Size; Rats; Rats, Wistar; Risk Assessment; Toxicity Tests, Acute; Toxicity Tests, Subchronic; Trimethoprim | 2015 |
Two-generation reproduction and teratology studies of feeding aditoprim in Wistar rats.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Female; Fetal Development; Male; Molecular Structure; No-Observed-Adverse-Effect Level; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Trimethoprim | 2015 |
Metabolism and Disposition of Aditoprim in Swine, Broilers, Carp and Rats.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Carps; Chickens; Chromatography, Liquid; Liver; Mass Spectrometry; Rats; Swine; Tissue Distribution; Trimethoprim | 2016 |
Simultaneous determination of aditoprim and its three major metabolites in pigs, broilers and carp tissues, and its application in tissue distribution and depletion studies.
Topics: Animals; Carps; Chickens; Chromatography, High Pressure Liquid; Molecular Structure; Swine; Tissue Distribution; Trimethoprim; Ultraviolet Rays | 2016 |
The antibacterial activities of aditoprim and its efficacy in the treatment of swine streptococcosis.
Topics: Animals; Anti-Bacterial Agents; Microbial Sensitivity Tests; Streptococcal Infections; Swine; Swine Diseases; Treatment Outcome; Trimethoprim | 2017 |
Broad-spectrum monoclonal antibody and a sensitive multi-residue indirect competitive enzyme-linked immunosorbent assay for the antibacterial synergists in samples of animal origin.
Topics: Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Enzyme-Linked Immunosorbent Assay; Haptens; Honey; Limit of Detection; Meat; Milk; Pyrimidines; Trimethoprim | 2019 |
Hydroxy-α-sanshool isolated from Zanthoxylum bungeanum attenuates learning and memory impairments in scopolamine-treated mice.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Fatty Acids, Unsaturated; Female; Gene Expression Regulation; Hippocampus; Humans; Learning; Magnetic Resonance Imaging; Male; Memory Disorders; Mice; Neurons; Polyunsaturated Alkamides; RNA, Messenger; Scopolamine; Trimethoprim; Zanthoxylum | 2019 |
Magnetic solid-phase extraction based on carbon nanotubes for determination of sulfamethoxazole, acetyl sulfamethoxazole and aditoprim residues in edible swine tissues with liquid chromatography tandem mass spectrometry.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Residues; Food Contamination; Humans; Limit of Detection; Magnetic Phenomena; Nanotubes, Carbon; Solid Phase Extraction; Sulfamethoxazole; Swine; Tandem Mass Spectrometry; Tissue Extracts; Trimethoprim; Veterinary Drugs | 2021 |