trimethoprim has been researched along with 2,4-diaminopyrimidine in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barrow, EW; Barrow, WW; Berlin, KD; Bourne, CR; Bourne, PC; Bunce, RA | 1 |
| Birdsall, B; Bowden, K; Feeney, J; Hall, AD; Roberts, GC | 1 |
| Padeĭskaia, EN | 1 |
| Ball, P | 1 |
| Gorrod, JW; Watkins, PJ | 1 |
| Chandrasekhar, J; Giacomini, MM; Hao, J; Lepist, EI; Liang, X; Ray, AS; Twelves, J; Whitney, JA | 1 |
| Chau, VQ; Daniel, S; Douglas, PM; Hulleman, JD; Mallipeddi, PL; Mihelakis, M; Niederstrasser, H; Peng, H; Posner, BA; Ramadurgum, P; Woodard, DR | 1 |
| Baptista, JA; Canotilho, J; Castro, RAE; Eusébio, MES; Évora, AOL; Maria, TMR; Ramos Silva, M; Rosado, MTS | 1 |
1 trial(s) available for trimethoprim and 2,4-diaminopyrimidine
| Article | Year |
|---|---|
[A new drug sulfaton in the combined treatment of infections with sulfanilamide derivatives and diaminopyrimidine].
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Drug Combinations; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Mice; Pyrimidines; Sulfamonomethoxine; Sulfanilamide; Sulfanilamides; Trimethoprim | 1989 |
7 other study(ies) available for trimethoprim and 2,4-diaminopyrimidine
| Article | Year |
|---|---|
Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1.
Topics: Anti-Bacterial Agents; Enzyme Inhibitors; Inhibitory Concentration 50; Microbial Sensitivity Tests; Protein Structure, Secondary; Protein Structure, Tertiary; Staphylococcus aureus; Tetrahydrofolate Dehydrogenase | 2010 |
Interactions between inhibitors of dihydrofolate reductase.
Topics: Benzenesulfonates; Binding Sites; Escherichia coli; Folic Acid Antagonists; Histidine; Hydrogen-Ion Concentration; Kinetics; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Methotrexate; Pyrimidines; Sulfonamides; Trimethoprim | 1989 |
Toxicity of sulphonamide-diaminopyrimidine combinations: implications for future use.
Topics: Anti-Infective Agents; Drug Combinations; Hematopoiesis; Humans; Pyrimidines; Sulfamethoxazole; Sulfonamides; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1986 |
Determination of isomeric N-oxide metabolites of some substituted 2,4-diaminopyrimidines by reversed-phase ion-pair high-performance liquid chromatography.
Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Cricetinae; Dioctyl Sulfosuccinic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Indicators and Reagents; Isomerism; Microsomes, Liver; Oxides; Pyrimethamine; Pyrimidines; Surface-Active Agents; Trimethoprim | 1993 |
Interaction of 2,4-Diaminopyrimidine-Containing Drugs Including Fedratinib and Trimethoprim with Thiamine Transporters.
Topics: Caco-2 Cells; Drug Interactions; HEK293 Cells; Humans; Janus Kinase Inhibitors; Membrane Transport Proteins; Molecular Structure; Pyrimidines; Pyrrolidines; Substrate Specificity; Sulfonamides; Thiamine; Trimethoprim | 2017 |
Simultaneous Control of Endogenous and User-Defined Genetic Pathways Using Unique ecDHFR Pharmacological Chaperones.
Topics: Animals; Anti-Bacterial Agents; Enzyme Inhibitors; Enzyme Stability; Escherichia coli; Female; Folic Acid Antagonists; HeLa Cells; Humans; Male; Mice; Mice, Inbred BALB C; Pyrimidines; Tetrahydrofolate Dehydrogenase; Triazines; Trimethoprim | 2020 |
Dihydrofolate Reductase Inhibitors: The Pharmacophore as a Guide for Co-Crystal Screening.
Topics: Crystallography, X-Ray; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Pyrimethamine; Pyrimidines; Tetrahydrofolate Dehydrogenase; Trimethoprim | 2021 |